The Molecular Signatures Database Hallmark Gene Set Collection

Cited by (1,112)

Items 601–700 of 1,112

1. Single-cell analysis of the aging female mouse hypothalamus
   Kaitlyn H. Hajdarovic, Doudou Yu, Lexi-Amber Hassell, Shane A. Evans, Sarah Packer, Nicola Neretti, Ashley E. Webb · 2022 · Nature Aging
2. Changes in Bone Marrow Tumor and Immune Cells Correlate with Durability of Remissions Following BCMA CAR T Therapy in Myeloma
   Kavita M. Dhodapkar, Adam D. Cohen, Akhilesh Kaushal, Alfred L. Garfall, Renee Julia Manalo, Allison R. Carr, Samuel Spence McCachren, Edward Allen Stadtmauer, Simon Francis Lacey, Jan Joseph Melenhorst et al. · 2022 · Blood Cancer Discovery
3. Evolutionary characterization of lung adenocarcinoma morphology in TRACERx
   Takahiro Karasaki, David Allan Moore, Selvaraju Veeriah, Cristina Naceur‐Lombardelli, Antonia Toncheva, Neil Magno, Sophia Ward, Maise Al Bakir, Thomas B.K. Watkins, Kristiana Grigoriadis et al. · 2023 · Nature Medicine
4. Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function
   Bin Gui, Fu Gui, Tomoaki Takai, Chao Feng, Xiao Bai, Ladan Fazli, Xuesen Dong, Shuai Liu, Xiaofeng Zhang, Wei Zhang et al. · 2019 · Proceedings of the National Academy of Sciences
5. Microglial microRNAs mediate sex-specific responses to tau pathology
   Kodama, Lay, Guzman, Elmer, Etchegaray, Jon I., Li, Yaqiao, Sayed, Faten A., Zhou, Lu, Zhou, Yungui, Zhan, Lihong, Le, David, Udeochu, Joe C. et al. · 2020 · Nature Neuroscience
6. Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms
   Janne Lehtiö, Taner Arslan, Ioannis Siavelis, Yanbo Pan, Fabio Socciarelli, Olena Berkovska, Husen Muhammad Umer, Georgios Mermelekas, Mohammad Pirmoradian, Mats Jönsson et al. · 2021 · Nature Cancer
7. Oxylipins and metabolites from pyroptotic cells act as promoters of tissue repair
   Parul Mehrotra, Sophia Maschalidi, Laura Boeckaerts, Christian Maueröder, Rochelle Tixeira, Jonathan J. Pinney, Javier Burgoa Cardás, Vladimir Sukhov, Yunus Incik, Christopher J. Anderson et al. · 2024 · Nature
8. Chimeric antigen receptor-modified macrophages ameliorate liver fibrosis in preclinical models
   Dai, Hanren, Zhu, Cheng, Huai, Qian, Xu, Wentao, Zhu, Jiejie, Zhang, Xu, Zhang, Xianzheng, Sun, Beicheng, Xu, Honghai, Zheng, Minghua et al. · 2024 · Journal of Hepatology
9. Complete regression of advanced pancreatic ductal adenocarcinomas upon combined inhibition of EGFR and C-RAF
   Blasco, María Teresa, Navas, Carolina, Martín-Serrano, Guillermo, Graña-Castro, Osvaldo, Lechuga, Carmen G., Martín-Díaz, Laura, Djurec, Magdolna, Li, Jing, Morales-Cacho, Lucia, Esteban-Burgos, Laura et al. · 2019 · Cancer Cell
10. Gene signatures of quiescent glioblastoma cells reveal mesenchymal shift and interactions with niche microenvironment
    Rut Tejero, Yong Huang, Igor Katsyv, Michael Kluge, Jung‐Yi Lin, Jessica Tomé-García, Nicolas Daviaud, Yuanshuo Wang, Bin Zhang, Nadejda M. Tsankova et al. · 2019 · EBioMedicine
11. TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases
    Bi-Huei Yang, Ke Wang, Shuo Wan, Yan Liang, Xiaomei Yuan, Yi Wei Dong, Sunglim Cho, Wanqing Xu, Kristen Jepsen, Gen‐Sheng Feng et al. · 2019 · Cell Reports
12. TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
    Jason Wayne Miklas, Elisa C. Clark, Shiri Levy, Damien Detraux, Andrea Leonard, Kevin M. Beussman, Megan Reed Showalter, Alec S.T. Smith, Peter Hofsteen, Xiulan Yang et al. · 2019 · Nature Communications
13. Significance of BRCA2 and RB1 Co-loss in Aggressive Prostate Cancer Progression
    Goutam Chakraborty, Joshua Armenia, Ying Zhang Mazzu, Subhiksha Nandakumar, Konrad Hermann Stopsack, Mohammad Omar Atiq, Kazumasa Komura, Lina E. Jehane, Rahim Hirani, Kalyani Chadalavada et al. · 2019 · Clinical Cancer Research
14. PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment
    Natalie Bucheimer Collins, Rose Al Abosy, Brian C. Miller, Kevin Bi, Qihong Zhao, Michael M. Quigley, Jeffrey Joseph Ishizuka, Kathleen B. Yates, Hans W. Pope, Robert T. Manguso et al. · 2022 · Journal for ImmunoTherapy of Cancer
15. Spatial mapping of transcriptomic plasticity in metastatic pancreatic cancer
    Guangsheng Pei, Jimin Min, Kimal Rajapakshe, Vittorio Branchi, Yunhe Liu, Benson Chellakkan Selvanesan, Fredrik I. Thege, Dorsay Sadeghian, Daiwei Zhang, Kyung Serk Cho et al. · 2025 · Nature
16. Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy
    David Martino, Melanie R. Neeland, Thanh D. Dang, Joanna E. Cobb, Justine A. Ellis, Alice Barnett, Mimi L.K. Tang, Peter Vuillermin, Katrina Jane Allen, Richard Saffery · 2018 · Nature Communications
17. Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden
    Tao Qing, Hussein Mohsen, Michał Marczyk, Yixuan Ye, Tess A. O’Meara, Hongyu Zhao, Jeffrey P. Townsend, Mark Gerstein, Christos Hatzis, Yuval Kluger et al. · 2020 · Nature Communications
18. Plant Adaptation and Tolerance to Environmental Stresses: Mechanisms and Perspectives
    Ali Raza, Farwa Ashraf, Xiling Zou, Xuekun Zhang, Hassan Tosif · 2020 · Springer eBooks
19. Pre-conditioning modifies the TME to enhance solid tumor CAR T cell efficacy and endogenous protective immunity
    John Paul Murad, Dileshni Tilakawardane, Anthony K. Park, Lupita S. Lopez, Cari A. Young, Jackson Gibson, Yukiko Yamaguchi, Hee Jun Lee, Kelly T. Kennewick, Brenna J. Gittins et al. · 2021 · Molecular Therapy
20. Spatial Transcriptomic Analysis of a Diverse Patient Cohort Reveals a Conserved Architecture in Triple-Negative Breast Cancer
    Rania Bassiouni, Michael O. Idowu, Lee D. Gibbs, Valentina Robila, Pamela J. Grizzard, Michelle G. Webb, Jiarong Song, Ashley Noriega, David Wesley Craig, John David Carpten · 2022 · Cancer Research
21. Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase
    Steffi Herold, Jacqueline Kalb, Gabriele Büchel, Carsten Patrick Ade, Apoorva Baluapuri, Jiajia Xu, Jan Köster, Daniel Solvie, Anne Carstensen, Christina Klotz et al. · 2019 · Nature
22. DNA hypermethylation during tuberculosis dampens host immune responsiveness
    Andrew R. DiNardo, Kimal Rajapakshe, Tomoki Nishiguchi, Godwin Mtetwa, Qiniso Dlamini, Jaqueline Kahari, Sanjana Mahapatra, Alexander Kay, Maphalala Gugu, Emily Mace et al. · 2020 · Journal of Clinical Investigation
23. The aging-related risk signature in colorectal cancer
    Taohua Yue, Shanwen Chen, Jing Zhu, Shihao Guo, Zhihao Huang, Pengyuan Wang, Shuai Zuo, Yucun Liu · 2021 · Aging
24. Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis
    Brian Yong Lee, Elizabeth K. J. Hogg, Christopher Below, Alexander Kononov, Adrián Blanco‐Gómez, Felix Heider, Jingshu Xu, Colin Hutton, Xiaohong Mary Zhang, Tamara Scheidt et al. · 2021 · Nature Communications
25. The cuproptosis-related signature associated with the tumor environment and prognosis of patients with glioma
    Weichen Wang, Zhichao Lu, Maoyu Wang, Zongheng Liu, Bing Wu, Chengkai Yang, Huan He, Peipei Gong · 2022 · Frontiers in Immunology
26. Cell cycle checkpoints cooperate to suppress DNA- and RNA-associated molecular pattern recognition and anti-tumor immune responses
    Chen, Jie, Harding, Shane M., Natesan, Ramakrishnan, Tian, Lei, Benci, Joseph L., Li, Weihua, Minn, Andy J., Asangani, Irfan A., Greenberg, Roger A. · 2020 · Cell Reports
27. CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity
    Sabine D. Jordan, Anna Kriebs, Megan E. Vaughan, Drew Duglan, Weiwei Fan, Emma Henriksson, Anne‐Laure Huber, Stephanie J. Papp, Madelena Nguyen, Megan E. Afetian et al. · 2017 · Cell Metabolism
28. Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
    Jason Yongsheng Chan, Jing Quan Lim, Joe Poh-Sheng Yeong, Vinod Ravi, Peiyong Guan, Arnoud Boot, Timothy Kwang Yong Tay, Sathiyamoorthy Selvarajan, Nur Diyana Md Nasir, Jie Hua Loh et al. · 2020 · Journal of Clinical Investigation
29. An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy
    Bassem D. Khalil, Roberto Sánchez, Tasrina Rahman, Carolina Rodríguez-Tirado, Stefan Moritsch, Alba Rodríguez Martínez, Brett A. Miles, Eduardo Farias, Mihaly Mezei, Ana Rita Nobre et al. · 2021 · The Journal of Experimental Medicine
30. The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses
    Melissa Erin Cook, Tara R. Bradstreet, Ashlee M. Webber, Jongshin Kim, Andrea C. Santeford, Kevin M. Harris, Maegan K Murphy, Jennifer Tran, Nada M. Abdalla, Elizabeth A. Schwarzkopf et al. · 2022 · Science Immunology
31. Systemic immune dysregulation in severe tuberculosis patients revealed by a single-cell transcriptome atlas
    Yi Wang, Qing Sun, Yun Zhang, Xuelian Li, Qingtao Liang, Ru Guo, Li‐Qun Zhang, Xiqin Han, Jing Wang, Lingling Shao et al. · 2023 · Journal of Infection
32. Polygenic regression uncovers trait-relevant cellular contexts through pathway activation transformation of single-cell RNA sequencing data
    Yunlong Ma, Chunyu Deng, Yijun Zhou, Yaru Zhang, Fei Qiu, Dingping Jiang, Gongwei Zheng, Jingjing Li, Jianwei Shuai, Yan Zhang et al. · 2023 · Cell Genomics
33. A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability
    Sirois, Isabelle, Aguilar-Mahecha, Adriana, Lafleur, Josiane, Fowler, Emma, Vu, Viet, Scriver, Michelle, Buchanan, Marguerite, Chabot, Catherine, Ramanathan, Aparna, Balachandran, Banujan et al. · 2019 · Molecular Cancer Research
34. Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells
    Anna Julie Peired, Giulia Antonelli, Maria Lucia Angelotti, Marco Allinovi, Francesco Guzzi, Alessandro Sisti, Roberto Semeraro, Carolina Conte, Benedetta Mazzinghi, Sara Nardi et al. · 2020 · Science Translational Medicine
35. Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer
    Artem Babaian, Katharina Rothe, Dylan J. Girodat, Igor Minia, Sara Djondovic, Miha Milek, Sandra E. Spencer Miko, Hans‐Joachim Wieden, Markus Landthaler, Gregg B. Morin et al. · 2020 · Cell Reports
36. Integrated proteogenomic characterization of urothelial carcinoma of the bladder
    Ning Xu, Zhenmei Yao, Guoguo Shang, Dingwei Ye, Haixing Wang, Hailiang Zhang, Yuanyuan Qu, Fujiang Xu, Yunzhi Wang, Zhaoyu Qin et al. · 2022 · Journal of Hematology & Oncology
37. Distinct transcriptome architectures underlying lupus establishment and exacerbation
    Masahiro Nakano, Mineto Ota, Yusuke Takeshima, Yukiko Iwasaki, Hiroaki Hatano, Yasuo Nagafuchi, Takahiro Itamiya, Junko Maeda, Ryochi Yoshida, Saeko Yamada et al. · 2022 · Cell
38. Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer
    Mary L. Stackpole, Weihua Zeng, Shuo Li, Chun-Chi Liu, Yonggang Zhou, Shanshan He, Angela Yeh, Ziye Wang, Fengzhu Sun, Qingjiao Li et al. · 2022 · Nature Communications
39. Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types
    Vitor Onuchic, Ryan James Hartmaier, David N. Boone, Michael L. Samuels, Ronak Y. Patel, Wendy White, Vesna D. Garovic, Steffi Oesterreich, Matt E. Roth, Adrian V. Lee et al. · 2016 · Cell Reports
40. Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma
    Mal Irvine, Ashleigh Stewart, Bernadette Pedersen, Suzanah C. Boyd, Richard F. Kefford, Helen Rizos · 2018 · Oncogenesis
41. Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus–Infected Cells and Liver to Identify Pathways Associated With Disease Development
    Joachim Lupberger, Tom Croonenborghs, Armando Andres Roca Suarez, Nicolaas Van Renne, Frank Jühling, Marine A. Oudot, Alessia Virzì, Simonetta Bandiera, Carole Jamey, Gergő Mészáros et al. · 2019 · Gastroenterology
42. Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data
    Ke Liu, Patrick A. Newbury, Benjamin Scott Glicksberg, Billy Zeng, Shreya Paithankar, Eran R. Andrechek, Bin Chen · 2019 · Nature Communications
43. A perturbed gene network containing PI3K–AKT, RAS–ERK and WNT–β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity
    Vahid Gazestani, Tiziano Pramparo, Srinivasa R. Nalabolu, Benjamin P. Kellman, Sarah Shaw Murray, Linda Lopez, Karen Pierce, Eric Courchesne, Nathan E. Lewis · 2019 · Nature Neuroscience
44. Evaluation of cisplatin-induced injury in human kidney organoids
    Jenny L. M. Digby, Thitinee Vanichapol, Aneta J. Przepiorski, Alan James Davidson, Veronika Sander · 2020 · American Journal of Physiology-Renal Physiology
45. FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease
    Susana García‐Recio, Aatish Thennavan, Michael P. East, Joel S. Parker, Juan Miguel Cejalvo, Joseph P. Garay, Daniel P. Hollern, Xiaping He, Kevin Raynard Mott, Patricia Galván et al. · 2020 · Journal of Clinical Investigation
46. The genomic and immune landscape of long-term survivors of high-grade serous ovarian cancer
    Dale W. Garsed, Ahwan Pandey, Sián Fereday, Catherine J. Kennedy, Kazuaki Takahashi, Kathryn Alsop, Phineas T. Hamilton, Joy Hendley, Yoke-Eng Chiew, Nadia Traficante et al. · 2022 · Nature Genetics
47. Innovative breakthroughs facilitated by single-cell multi-omics: manipulating natural killer cell functionality correlates with a novel subcategory of melanoma cells
    Zhijie Zhao, Yantao Ding, Lisa Jia Tran, Gang Chai, Lin Li · 2023 · Frontiers in Immunology
48. JAK-STAT signaling maintains homeostasis in T cells and macrophages
    Nikolaus Fortelny, Matthias Farlik, Victoria Elisabeth Richardsdot Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha et al. · 2024 · Nature Immunology
49. PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression
    Lee, Keun-Woo, Yeo, So-Young, Gong, Jeong-Ryeol, Koo, Ok-Jae, Sohn, Insuk, Lee, Woo Yong, Kim, Hee Cheol, Yun, Seong Hyeon, Cho, Yong Beom, Choi, Mi-Ae et al. · 2022 · Nature Communications
50. Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition
    Stopfer, Lauren E., Mesfin, Joshua M., Joughin, Brian A., Lauffenburger, Douglas A., White, Forest M. · 2020 · Nature Communications
51. NAD+ Regeneration Rescues Lifespan But Not Ataxia in a Mouse Model of Brain Mitochondrial Complex I Dysfunction
    Gregory Scott McElroy, Colleen R. Reczek, Paul A. Reyfman, Divakar S. Mithal, Craig Horbinski, Navdeep S. Chandel · 2019 · Cell Metabolism
52. Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity
    Samuel Martins Gonçalves, Cláudio Duarte‐Oliveira, Cláudia F. Campos, Vishukumar Aimanianda, Rob ter Horst, Luis Leite, Toine Mercier, Paulo N. G. Pereira, Miguel Fernández-García, Daniela Antunes et al. · 2020 · Nature Communications
53. Single-Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell
    Minzhe Guo, Jane J. Yu, Anne‐Karina T. Perl, Kathryn A. Wikenheiser‐Brokamp, Matthew Riccetti, Erik Y. Zhang, Parvathi Sudha, Mike Adam, Andrew Potter, Elizabeth J. Kopras et al. · 2020 · American Journal of Respiratory and Critical Care Medicine
54. Single-Cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning
    Jason S. Hong, Douglas V. Arneson, Soban Umar, Grégoire Ruffenach, Christine Marie Cunningham, In Sook Ahn, Graciel Diamante, May Bhetraratana, John F. Park, Emma Said et al. · 2020 · American Journal of Respiratory and Critical Care Medicine
55. Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
    Paola Brandi, Laura Conejero, Francisco J. Cueto, Sarai Martínez-Cano, Gillian Dunphy, Manuel J. Gómez, Carlos Relaño‐Rupérez, Paula Saz-Leal, Michel Enamorado, Ana Quintas et al. · 2022 · Cell Reports
56. Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo
    Luis Francisco Lorenzo‐Martín, Tania Hübscher, Amber D. Bowler, Nicolas Broguière, Jakob Langer, Lucie Tillard, Mikhail Nikolaev, Freddy Radtke, Matthias P. Lütolf · 2024 · Nature
57. Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
    Jelena Petrovic, Yeqiao Zhou, Maria Fasolino, Naomi Goldman, Gregory W. Schwartz, Maxwell R. Mumbach, Son C. Nguyen, Kelly Rome, Yogev Sela, Zachary Zapataro et al. · 2019 · Molecular Cell
58. RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas
    Manfred Kunz, Henry Loeffler‐Wirth, Michael Dannemann, Edith Willscher, Gero Doose, Janet F. Kelso, Tina Kottek, Birgit Nickel, Lydia Hopp, Jenny Landsberg et al. · 2018 · Oncogene
59. Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker
    Guido Baselli, Paola Dongiovanni, Raffaela Rametta, Marica Meroni, Serena Pelusi, Marco Maggioni, Sara Badiali, Piero Pingitore, Samantha Maurotti, Tiziana Montalcini et al. · 2020 · Gut
60. Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
    Irem Ozkan‐Dagliyan, J. Nathaniel Diehl, Samuel D. George, Antje Schaefer, Bjoern Papke, Kathleen Klotz‐Noack, Andrew M. Waters, Craig M. Goodwin, Prson Gautam, Mariaelena Pierobon et al. · 2020 · Cell Reports
61. A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia
    Roderick Docking, Jeremy Parker, Martin Jädersten, Gerben Duns, Linda Chang, Jihong Jiang, Jessica A. Pilsworth, Lucas Swanson, Simon K. Chan, Readman Chiu et al. · 2021 · Nature Communications
62. Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth
    Adi Laurentiu Tarca, Bálint Pataki, Roberto J. Romero, Marina Sirota, Yuanfang Guan, Rintu Kutum, Nardhy Gomez‐Lopez, Bogdan Done, Gaurav Bhatti, Thomas Von Yu et al. · 2021 · Cell Reports Medicine
63. Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection
    Xuanyu Liu, Wen Chen, Guoyan Zhu, Hang Yang, Wenke Li, Mingyao Luo, Chang Shu, Zhou Zhou · 2022 · Cell Discovery
64. C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection
    Jigar V. Desai, Dhaneshwar Kumar, Tilo Freiwald, Daniel Chauss, Melissa D. Johnson, Michael S. Abers, Julie M. Steinbrink, John R. Perfect, Barbara Dudley Alexander, Vasiliki Matzaraki et al. · 2023 · Cell
65. SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
    Giuseppe Leuzzi, Alessandro Vasciaveo, Angelo Taglialatela, Xiao Chen, Tessa M. Firestone, Allison R. Hickman, Wendy Mao, Tanay Thakar, Alina Vaitsiankova, Jen‐Wei Huang et al. · 2024 · Cell
66. DrugMap: A quantitative pan-cancer analysis of cysteine ligandability
    Mariko Takahashi, Harrison Byron Chong, Siwen Zhang, Tzu-yi Yang, Matthew J. Lazarov, Stefan Andrew Harry, Michelle Maynard, Brendan J. Hilbert, Ryan D. White, Heather E. Murrey et al. · 2024 · Cell
67. Abundance of Regulatory T Cell (Treg) as a Predictive Biomarker for Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer
    Masanori Oshi, Mariko Asaoka, Yoshihisa Tokumaru, Fernando A. Angarita, Li Yan, Ryusei Matsuyama, Emese Zsíros, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe · 2020 · Cancers
68. Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes
    Adam Benjamin Weiner, Thiago Vidotto, Yang Liu, Adrianna Amaral de Aragao Mendes, Daniela Correia Salles, Farzana A. Faisal, Sanjana Murali, Matthew McFarlane, Eddie L. Imada, Xin Zhao et al. · 2021 · Nature Communications
69. A pan-cancer organoid platform for precision medicine
    Larsen, Brian M., Kannan, Madhavi, Langer, Lee F., Leibowitz, Benjamin D., Bentaieb, Aicha, Cancino, Andrea, Dolgalev, Igor, Drummond, Bridgette E., Dry, Jonathan R., Ho, Chi-Sing et al. · 2021 · Cell Reports
70. Genome-wide analysis of somatic noncoding mutation patterns in cancer
    Felix Dietlein, Alex B. Wang, Christian R. Fagre, Anran Tang, Nicolle J.M. Besselink, Edwin P. J. G. Cuppen, Chunliang Li, Shamil R. Sunyaev, James T. Neal, Eliezer M. Van Allen · 2022 · Science
71. Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection
    Aaqib Sohail, Azeem Iqbal, Nishika Sahini, Fangfang Chen, Mohamed A. Tantawy, Syed Fakhar‐ul‐Hassnain Waqas, Moritz Winterhoff, Thomas Ebensen, Kristin Schultz, Robert Geffers et al. · 2022 · PLoS Pathogens
72. Immune infiltration and clinical significance analyses of the coagulation-related genes in hepatocellular carcinoma
    Qifan He, Jian Yang, Yonghai Jin · 2022 · Briefings in Bioinformatics
73. Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues
    Margaret M. Lowe, Ian C. Boothby, Sean Clancy, Richard S. Ahn, Wilson J. Liao, David N. Nguyen, Kathrin Schumann, Alexander Marson, Kelly M. Mahuron, Gillian A. Kingsbury et al. · 2019 · JCI Insight
74. The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization
    Naoya Takayama, Alex Murison, Shin‐ichiro Takayanagi, Christopher Arlidge, Stanley Zhou, Laura García‐Prat, Michelle Chan‐Seng‐Yue, Sasan Zandi, Olga I. Gan, Héléna Boutzen et al. · 2020 · Cell stem cell
75. HIF1A signaling selectively supports proliferation of breast cancer in the brain
    Richard Y. Ebright, Marcus A. Zachariah, Douglas Scott Micalizzi, Ben S. Wittner, Kira Niederhoffer, Linda T. Nieman, Brian Chirn, Devon F. Wiley, Benjamin Wesley, Brian L. Shaw et al. · 2020 · Nature Communications
76. CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells
    Sushil Kumar, Zexian Zeng, Archis Bagati, Rong En Tay, Lionel A. Sanz, Stella R. Hartono, Yoshinaga Ito, Fieda O. Abderazzaq, Elodie Hatchi, Peng Jiang et al. · 2021 · Cancer Discovery
77. Urea cycle activation triggered by host-microbiota maladaptation driving colorectal tumorigenesis
    Haoyan Chen, Tianying Tong, Shiyuan Lu, Linhua Ji, Baoqin Xuan, Gang Zhao, Yuqing Yan, Linhong Song, Licong Zhao, Yile Xie et al. · 2023 · Cell Metabolism
78. Multimodal deep learning to predict prognosis in adult and pediatric brain tumors
    Sandra Steyaert, Yeping Lina Qiu, Yuanning Zheng, Pritam Mukherjee, Hannes S. Vogel, Olivier Gevaert · 2023 · Communications Medicine
79. A pairwise cytokine code explains the organism-wide response to sepsis
    Michihiro Takahama, Ashwini Patil, Katherine Johnson, Denis Cipurko, Yoshimi Miki, Yoshitaka Taketomi, Peter S. Carbonetto, Madison Plaster, Gabriella Richey, Surya Pandey et al. · 2024 · Nature Immunology
80. Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition
    Tsai, Yihsuan S., Woodcock, Mark G., Azam, Salma H., Thorne, Leigh B., Kanchi, Krishna L., Parker, Joel S., Vincent, Benjamin G., Pecot, Chad V. · 2022 · Journal of Clinical Investigation
81. Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren's syndrome
    Shinya Tasaki, Katsuya Suzuki, Ayumi Nishikawa, Yoshiaki Kassai, Maiko Takiguchi, Rina Kurisu, Yuumi Okuzono, Takahiro Miyazaki, Masaru Takeshita, Keiko Yoshimoto et al. · 2017 · Annals of the Rheumatic Diseases
82. Pluripotency Surveillance by Myc-Driven Competitive Elimination of Differentiating Cells
    Covadonga Díaz-Díaz, Laura Fernández de Manuel, Daniel Jiménez‐Carretero, Marı́a C. Montoya, Cristina Claverı́a, Miguel Torres · 2017 · Developmental Cell
83. Efficient prediction of a spatial transcriptomics profile better characterizes breast cancer tissue sections without costly experimentation
    Taku Monjo, Masaru Koido, Satoi Nagasawa, Yutaka Suzuki, Yoichiro Kamatani · 2022 · Scientific Reports
84. Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis
    Xuanzhang Huang, Min-Jiao Pang, Jia-Yi Li, Hanyu Chen, Jingxu Sun, Yongxi Song, Hong-Jie Ni, Shi-Yu Ye, Shi Bai, Tenghui Li et al. · 2023 · Nature Communications
85. Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression
    Kie Kyon Huang, Haoran Ma, Roxanne Hui Heng Chong, Tomoyuki Uchihara, Benedict Shi Xiang Lian, Feng Zhu, Taotao Sheng, Supriya Srivastava, Su Ting Tay, Raghav Sundar et al. · 2023 · Cancer Cell
86. Reconstructing growth and dynamic trajectories from single-cell transcriptomics data
    Yutong Sha, Yuchi Qiu, Peijie Zhou, Qing Hua Nie · 2023 · Nature Machine Intelligence
87. Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results
    Sergio Crespo‐Garcia, Frédérik Fournier, Roberto Diaz-Marin, Sharon M. Klier, Derek Ragusa, Lauren Masaki, Gaël Cagnone, Guillaume Blot, Ikhlas Hafiane, Agnieszka Dejda et al. · 2024 · Nature Medicine
88. Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma
    Gullà, A, Hideshima, T, Bianchi, G, Fulciniti, M, Kemal Samur, M, Qi, J, Tai, Y-T, Harada, T, Morelli, E, Amodio, N et al. · 2018 · Leukemia
89. Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer
    Qian Du, Saul A. Bert, Nicola J. Armstrong, Catherine Elizabeth Caldon, Jenny Z. Song, Shalima S. Nair, Cathryn M. Gould, Phuc‐Loi Luu, Timothy J. Peters, Amanda Khoury et al. · 2019 · Nature Communications
90. LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial–Mesenchymal Transition
    Hongshi Cai, Jiaxin Li, Yadong Zhang, Yan Liao, Yue Zhu, Cheng Wang, Jinsong Hou · 2019 · Frontiers in Oncology
91. Transcriptional effects of copy number alterations in a large set of human cancers
    Arkajyoti Bhattacharya, Rico D. Bense, Carlos G. Urzúa-Traslaviña, Elisabeth G.E. de Vries, Marcel A.T.M. van Vugt, Rudolf S.N. Fehrmann · 2020 · Nature Communications
92. Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor
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