The Molecular Signatures Database Hallmark Gene Set Collection

Cited by (1,112)

Items 801–900 of 1,112

1. Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition
   Yi‐Hsuan Tsai, Mark G. Woodcock, Salma H. Azam, Leigh B. Thorne, Krishna Kanchi, Joel S. Parker, Benjamin Garrett Vincent, Chad Victor Pecot · 2022 · DOAJ (DOAJ: Directory of Open Access Journals)
2. Survival Genie, a web platform for survival analysis across pediatric and adult cancers
   Bhakti Dwivedi, Hope Mumme, Sarthak Satpathy, Swati Sharma Bhasin, Manoj Bhasin · 2022 · Scientific Reports
3. Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer
   Uta Margareta Demel, Marlitt Böger, Schayan Yousefian, Corinna Grunert, Le Zhang, Paul W. Hotz, Adrian Gottschlich, Hazal Köse, Konstandina Isaakidis, Dominik Vonficht et al. · 2022 · Journal of Clinical Investigation
4. Consensus molecular subtype classification of colorectal adenomas
   Komor, Malgorzata A, Bosch, Linda JW, Bounova, Gergana, Bolijn, Anne S, Delis‐van Diemen, Pien M, Rausch, Christian, Hoogstrate, Youri, Stubbs, Andrew P, de Jong, Mark, Jenster, Guido et al. · 2018 · The Journal of Pathology
5. The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers
   Elisa Monzón‐Casanova, Michael Screen, Manuel D. Díaz‐Muñoz, Richard Coulson, Sarah E. Bell, Greta Lamers, Michele Solimena, Christopher W. J. Smith, Martin Turner · 2018 · Nature Immunology
6. A survey and systematic assessment of computational methods for drug response prediction
   Jinyu Chen, Louxin Zhang · 2019 · Briefings in Bioinformatics
7. Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal
   Takeshi Inoue, Ryo Shinnakasu, Kawai Chie, Wataru Ise, Eiryo Kawakami, Nicolas Sax, Toshihiko Oki, Toshio Kitamura, Kazuo Yamashita, Hidehiro Fukuyama et al. · 2020 · The Journal of Experimental Medicine
8. Comparative Genomics Reveals Distinct Immune-oncologic Pathways in African American Men with Prostate Cancer
   Shivanshu Awasthi, Anders Berglund, Julieta Abraham-Miranda, Robert J. Rounbehler, Kevin H. Kensler, Amparo N. Serna, Adriana C. Vidal, Sungyong You, Michael R. Freeman, Elai Davicioni et al. · 2020 · Clinical Cancer Research
9. Diverse Routes toward Early Somites in the Mouse Embryo
   Carolina Guibentif, Jonathan A. Griffiths, Iván Imaz-Rosshandler, Shila Ghazanfar, Jennifer Nichols, Valerie A. Wilson, Berthold Göttgens, John C. Marioni · 2020 · Developmental Cell
10. Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy
    Christina E. DeStefano Shields, James Robert White, Liam Chung, Alyssa N. Wenzel, Jessica L Hicks, Ada J Tam, June L. Chan, Christine M. Dejea, Hongni Fan, John H. Michel et al. · 2021 · Cancer Discovery
11. Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank
    Keira J.A. Johnston, Joey Ward, Pradipta R. Ray, Mark J. Adams, Andrew Mark McIntosh, Blair H. Smith, Rona J. Strawbridge, Theodore John Price, Daniel J. Smıth, Barbara I. Nicholl et al. · 2021 · PLoS Genetics
12. Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
    Benjamin D. Gastfriend, Hideaki Nishihara, Scott Glen Canfield, Koji L Foreman, Britta Engelhardt, Sean P. Palecek, Eric V Shusta · 2021 · eLife
13. Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities
    Jian Lin, Yuting Dai, Chen Sang, Guohe Song, Bin Xiang, Mao Zhang, Liangqing Dong, Xiaoli Xia, Jiaqiang Ma, Xia Shen et al. · 2022 · Journal for ImmunoTherapy of Cancer
14. Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer
    Nikki L. Burdett, Madelynne O. Willis, Kathryn Alsop, Allison L. Hunt, Ahwan Pandey, Phineas T. Hamilton, Tamara S. Abulez, Xuan Liu, Therese Hoang, Stuart Craig et al. · 2023 · Nature Genetics
15. Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma
    Katie Marie Campbell, Meelad Amouzgar, Shannon M. Pfeiffer, Timothy R. Howes, Egmidio Medina, Michael Travers, Gabriela Steiner, Jeffrey S. Weber, Jedd D. Wolchok, James Larkin et al. · 2023 · Cancer Cell
16. Human and mouse neutrophils share core transcriptional programs in both homeostatic and inflamed contexts
    Nicolaj S. Hackert, Felix A. Radtke, Tarik Exner, Hanns‐Martin Lorenz, Carsten Müller‐Tidow, Peter Andrija Nigrovic, Guido H. Wabnitz, Ricardo Grieshaber‐Bouyer · 2023 · Nature Communications
17. Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatohepatitis
    Chittampalli N. Yashaswini, Tianyue Qin, Dipankar Bhattacharya, Corina Amor, Scott W. Lowe, Amaia Lujambio, Shuang Wang, Scott L. Friedman · 2024 · Journal of Hepatology
18. Nanoceria-Mediated Cyclosporin A Delivery for Dry Eye Disease Management through Modulating Immune–Epithelial Crosstalk
    Wenyu Cui, Sheng Chen, Tianyi Hu, Tinglian Zhou, Chen Qiu, Luyang Jiang, Xiaoyu Cheng, Jian Ji, Ke Yao, Haijie Han · 2024 · ACS Nano
19. Proteomic changes upon treatment with semaglutide in individuals with obesity
    Maretty, Lasse, Gill, Dipender, Simonsen, Lotte, Soh, Keng, Zagkos, Loukas, Galanakis, Michael, Sibbesen, Jonas, Iglesias, Miquel Triana, Secher, Anna, Valkenborg, Dirk et al. · 2025 · Nature Medicine
20. Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design
    Yushen Du, Xin Li, Yuan Shi, Tian-hao Zhang, Nicholas C. Wu, Lei Dai, Danyang Gong, Gurpreet Brar, Sara Shu, Jiadi Luo et al. · 2018 · Science
21. Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut Microbiota in Mice
    Naoki Sasaki, Sayaka Katagiri, Rina Komazaki, Kazuki Watanabe, Shogo Maekawa, Takahiko Shiba, Sayuri Udagawa, Yasuo Takeuchi, Anri Ohtsu, Takashi Kohda et al. · 2018 · Frontiers in Microbiology
22. RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution
    Qi Liu, Tanya Shvarts, Piotr Sliz A, Richard I. Gregory · 2020 · Nucleic Acids Research
23. Lineage Reversion Drives WNT Independence in Intestinal Cancer
    Teng Han, Sukanya Goswami, Yang Hu, Fanying Tang, María Paz Zafra, Charles J. Murphy, Zhen Cao, John Thomas Poirier, Ekta Khurana, Olivier Elemento et al. · 2020 · Cancer Discovery
24. Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours
    Lars Custers, Eleonora Khabirova, Tim H. H. Coorens, Thomas R. W. Oliver, Camilla Calandrini, Matthew D. Young, Felipe A. Vieira Braga, Peter Ellis, Lira Mamanova, Heidi Segers et al. · 2021 · Nature Communications
25. Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences
    Walter Rayford, Alp Tuna Beksac, Jordan Alger, Mohammed Alshalalfa, Mohsen Ahmed, Irtaza Khan, Ugo Giovanni Falagario, Yang Liu, Elai Davicioni, Daniel Eidelberg Spratt et al. · 2021 · Communications Biology
26. Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells
    Ruoxi W. Wang, Sonia Viganò, Uri Ben‐David, Angelika Amon, Stefano Santaguida · 2021 · EMBO Reports
27. Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response, and worse survival in breast cancer
    Masanori Oshi, Shipra Gandhi, Li Yan, Yoshihisa Tokumaru, Rongrong Wu, Akimitsu Yamada, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe · 2022 · Breast Cancer Research and Treatment
28. Single-cell transcriptome profiling and chromatin accessibility reveal an exhausted regulatory CD4+ T cell subset in systemic lupus erythematosus
    Chuang Guo, Qian Liu, Dandan Zong, Wen Zhang, Zu-Qi Zuo, Qiaoni Yu, Qing Sha, Lin Zhu, Xuyuan Gao, Jingwen Fang et al. · 2022 · Cell Reports
29. A single-cell transcriptomic landscape of mouse testicular aging
    Wei Zhang, Siyu Xia, Wei Lie Xiao, Yali Song, Li Tang, Min Cao, Jing Yang, Shuang Wang, Zhijie Li, Chengchao Xu et al. · 2022 · Journal of Advanced Research
30. CROST: a comprehensive repository of spatial transcriptomics
    Guoliang Wang, Song Wu, Zhuang Xiong, Hongzhu Qu, Xiangdong Fang, Yīmíng Bào · 2023 · Nucleic Acids Research
31. Molecular pathological classification of colorectal cancer—an update
    Philip D. Dunne, Mark Johan Arends · 2024 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
32. Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19
    Aimee Hanson, Matthew P. Mulè, Hélène Ruffieux, Federica Mescia, Laura Bergamaschi, Victoria S. Pelly, Lorinda Turner, Prasanti Kotagiri, Berthold Göttgens, Christoph Hess et al. · 2024 · Nature Immunology
33. Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease
    Kimura, Kimitoshi, Subramanian, Ayshwarya, Yin, Zhuoran, Khalilnezhad, Ahad, Wu, Yufan, He, Danyang, Dixon, Karen O., Chitta, Udbhav Kasyap, Ding, Xiaokai, Adhikari, Niraj et al. · 2025 · Nature
34. Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer
    Cowman, Sophie J., Fuja, Daniel G., Liu, Xian-De, Tidwell, Rebecca S. Slack, Kandula, Neelima, Sirohi, Deepika, Agarwal, Archana M., Emerson, Lyska L., Tripp, Sheryl R., Mohlman, Jeffrey S. et al. · 2020 · Clinical Cancer Research
35. PD-L1 and tumor-associated macrophages in de novo DLBCL
    Ronald McCord, Christopher R. Bolen, Hartmut Koeppen, Edward Ernest Kadel, Mikkel Z. Oestergaard, Tina G. Nielsen, Laurie Helen Sehn, Jeffrey Michael Venstrom · 2019 · Blood Advances
36. ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells
    Ana Jimenez‐Pascual, James S. Hale, Anja Kordowski, Jamie Pugh, Daniel J. Silver, Defne Bayık, Gustavo A. Roversi, Tyler Joseph Alban, Shilpa C. Rao, Rui Chen et al. · 2019 · Cancer Discovery
37. Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+T Cells
    Deanna A. Kulpa, Aarthi Talla, Jessica H. Brehm, Susan Pereira Ribeiro, Sally Yuan, Anne-Gaelle Bebin-Blackwell, Michael D. Miller, Richard Barnard, Steven G. Deeks, Daria J. Hazuda et al. · 2019 · Journal of Virology
38. Analysis of gene expression signatures identifies prognostic and functionally distinct ovarian clear cell carcinoma subtypes
    Tuan Zea Tan, Jieru Ye, Chung Vin Yee, Diana Gkeok Stzuan Lim, Natalie Y.L. Ngoi, David S.P. Tan, Ruby Yun‐Ju Huang · 2019 · EBioMedicine
39. Expression of T-Cell Exhaustion Molecules and Human Endogenous Retroviruses as Predictive Biomarkers for Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma
    Miriam Ficial, Opeyemi A. Jegede, Miriam Sant’Angelo, Yue Hou, Abdallah Flaifel, Jean‐Christophe Pignon, David A. Braun, Megan Wind‐Rotolo, Maura Aliezah Sticco-Ivins, Paul J. Catalano et al. · 2020 · Clinical Cancer Research
40. ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation
    Sun, Tianliang, Annunziato, Stefano, Bergling, Sebastian, Sheng, Caibin, Orsini, Vanessa, Forcella, Pascal, Pikiolek, Monika, Kancherla, Venkatesh, Holwerda, Sjoerd, Imanci, Dilek et al. · 2021 · Cell Stem Cell
41. Predicting Molecular Phenotypes from Histopathology Images: A Transcriptome-Wide Expression–Morphology Analysis in Breast Cancer
    Yinxi Wang, Kimmo Kartasalo, Philippe Weitz, Balázs Ács, Masi Valkonen, Christer Larsson, Pekka Ruusuvuori, Johan Hartman, Mattias Rantalainen · 2021 · Cancer Research
42. A Phase I, Open-Label, Dose-Escalation Study of the OX40 Agonist Ivuxolimab in Patients with Locally Advanced or Metastatic Cancers
    Adi Diab, Omid Hamid, John A. Thompson, Willeke Ros, Ferry A.L.M. Eskens, Toshihiko Doi, Siwen Hu-Lieskovan, Samuel J. Klempner, Bishu Ganguly, Catherine Fleener et al. · 2021 · Clinical Cancer Research
43. Single-cell transcriptome analysis reveals three sequential phases of gene expression during zebrafish sensory hair cell regeneration
    Sungmin Baek, Nhung T. T. Tran, Daniel C. Diaz, Ya-Yin Tsai, Joaquín Navajas Acedo, Mark E. Lush, Tatjana Piotrowski · 2022 · Developmental Cell
44. Generation of human islet cell type-specific identity genesets
    Léon van Gurp, Leon Fodoulian, Daniel Oropeza, Kenichiro Furuyama, Eva Bru-Tarí, Anh Nguyet Vu, John S. Kaddis, Iván Rodríguez, Fabrizio Thorel, Pedro Luis Herrera · 2022 · Nature Communications
45. Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity
    Roux, Antoine E., Zhang, Chunlian, Paw, Jonathan, Zavala-Solorio, José, Malahias, Evangelia, Vijay, Twaritha, Kolumam, Ganesh, Kenyon, Cynthia, Kimmel, Jacob C. · 2022 · Cell Systems
46. Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers
    Meenakshi Anurag, Nindo B. Punturi, Jeremy Hoog, Matthew Neil Bainbridge, Matthew J. Ellis, Svasti Haricharan · 2018 · Clinical Cancer Research
47. A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer
    Singhal, Anupriya, Styers, Hannah C., Rub, Jonathan, Li, Zhuxuan, Torborg, Stefan R., Kim, Jung Yun, Grbovic-Huezo, Olivera, Feng, Huijin, Tarcan, Zeynep Cagla, Sahin Ozkan, Hulya et al. · 2024 · Cancer Discovery
48. Personalization of Logical Models With Multi-Omics Data Allows Clinical Stratification of Patients
    Jonas Béal, Arnau Montagud, Pauline Traynard, Emmanuel Barillot, Laurence Calzone · 2019 · Frontiers in Physiology
49. Omics Playground: a comprehensive self-service platform for visualization, analytics and exploration of Big Omics Data
    Murodzhon Akhmedov, Axel Martinelli, Roger Geiger, Ivo Kwee · 2019 · NAR Genomics and Bioinformatics
50. Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate
    Hideo Takahashi, Mariko Asaoka, Li Yan, Omar Maen Rashid, Masanori Oshi, Takashi Ishikawa, Masayuki Nagahashi, Kazuaki Takabe · 2020 · Scientific Reports
51. CCND1 Amplification Contributes to Immunosuppression and Is Associated With a Poor Prognosis to Immune Checkpoint Inhibitors in Solid Tumors
    Yu Chen, Yingying Huang, Xuan Gao, Yi Li, Jing Lin, Lizhu Chen, Lianpeng Chang, Gang Chen, Yanfang Guan, Leong Kin Pan et al. · 2020 · Frontiers in Immunology
52. Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development
    Edie I. Crosse, Sabrina A.M. Gordon-Keylock, Рыбцов Станислав Александрович, Anahí Binagui-Casas, Hannah Felchle, Nneka C. Nnadi, Kristina Kirschner, Tamir Chandra, Sara Tamagno, David John Webb et al. · 2020 · Cell stem cell
53. Single-cell RNA sequencing reveals the sustained immune cell dysfunction in the pathogenesis of sepsis secondary to bacterial pneumonia
    Teng Wang, Xianglong Zhang, Zhanguo Liu, Tong Yao, Dongying Zheng, Jianwei Gan, Shuang Yu, Lin Li, Peng Chen, Jian Sun · 2021 · Genomics
54. Cellular stress promotes NOD1/2‐dependent inflammation via the endogenous metabolite sphingosine‐1‐phosphate
    Gang Pei, Joanna Żyła, Lichun He, Pedro Moura‐Alves, Heidrun Steinle, Philippe Saikali, Laura Lozza, Natalie Eva Nieuwenhuizen, January Mikolaj Weiner, Hans‐Joachim Mollenkopf et al. · 2021 · The EMBO Journal
55. Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
    Joshua D.G. Leach, Nikola Vlahov, Petros K. Tsantoulis, Rachel A. Ridgway, Dustin James Flanagan, Kathryn L. Gilroy, Nathalie Sphyris, Ester Gil Vázquez, David F. Vincent, William J. Faller et al. · 2021 · Nature Communications
56. DPP inhibition alters the CXCR3 axis and enhances NK and CD8+ T cell infiltration to improve anti-PD1 efficacy in murine models of pancreatic ductal adenocarcinoma
    Allison A. Fitzgerald, Shangzi Wang, Veena R. Agarwal, Emily F. Davis-Marcisak, Annie Zuo, Sandra A. Jablonski, Melanie Loth, Elana Judith Fertig, John R. MacDougall, Eugene A. Zhukovsky et al. · 2021 · Journal for ImmunoTherapy of Cancer
57. Construction of a Lactate-Related Prognostic Signature for Predicting Prognosis, Tumor Microenvironment, and Immune Response in Kidney Renal Clear Cell Carcinoma
    Zhuolun Sun, Wen Tao, Xudong Guo, Changying Jing, Mingxiao Zhang, Zhenqing Wang, Feng Kong, Ning Suo, Shaobo Jiang, Hanbo Wang · 2022 · Frontiers in Immunology
58. Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity
    Longchao Liu, Jiahui Chen, Hongyi Zhang, Jianfeng Ye, Casey Moore, Changzheng Lu, Yan Fang, Yang‐Xin Fu, Bo Li · 2022 · Nature Cancer
59. Geospatial Immune Heterogeneity Reflects the Diverse Tumor–Immune Interactions in Intrahepatic Cholangiocarcinoma
    Youpei Lin, Lihua Peng, Liangqing Dong, Dongbing Liu, Jiaqiang Ma, Jian Lin, Xiaofang Chen, Penghui Lin, Guohe Song, Mao Zhang et al. · 2022 · Cancer Discovery
60. Single cell deciphering of progression trajectories of the tumor ecosystem in head and neck cancer
    Z. L. Liu, Xiangyan Meng, Rujuan Bao, M. Y. Shen, J. J. Sun, W. D. Chen, Fei‐Fei Liu, Yue He · 2024 · Nature Communications
61. Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer
    Klomp, Jennifer E., Diehl, J. Nathaniel, Klomp, Jeffrey A., Edwards, A. Cole, Yang, Runying, Morales, Alexis J., Taylor, Khalilah E., Drizyte-Miller, Kristina, Bryant, Kirsten L., Schaefer, Antje et al. · 2024 · Science
62. Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
    Ietswaart, Robert, Smalec, Brendan M., Xu, Albert, Choquet, Karine, McShane, Erik, Jowhar, Ziad Mohamoud, Guegler, Chantal K., Baxter-Koenigs, Autum R., West, Emma R., Fu, Becky Xu Hua et al. · 2024 · Molecular Cell
63. A pan-cancer single-cell RNA-seq atlas of intratumoral B cells
    Evelyn Fitzsimons, Danwen Qian, Andrei Enica, Krupa Thakkar, Marcellus Augustine, Samuel Gamble, James L. Reading, Kevin Litchfield · 2024 · Cancer Cell
64. Optimized Dynamic Network Biomarker Deciphers a High‐Resolution Heterogeneity Within Thyroid Cancer Molecular Subtypes
    Haonan Zhang, Ge Zhang, Pengyuan Xu, Fengyi Yu, Liwen Li, Runzhi Huang, Zhenfa Zhang, Kaisaierjiang Kadier, Yuanyuan Wang, Qiqi Gu et al. · 2025 · Med Research
65. A JAK1 Selective Kinase Inhibitor and Tofacitinib Affect Macrophage Activation and Function
    Leonie C.S. De Vries, J M Duarte, Manon de Krijger, Olaf Welting, Patricia H. P. van Hamersveld, F W M Van Leeuwen-Hilbers, Perry D. Moerland, Aldo Jongejan, Geert D’Haens, Wouter J. de Jonge et al. · 2019 · Inflammatory Bowel Diseases
66. A cross-species proteomic map reveals neoteny of human synapse development
    Wang, Li, Pang, Kaifang, Zhou, Li, Cebrián-Silla, Arantxa, González-Granero, Susana, Wang, Shaohui, Bi, Qiuli, White, Matthew L., Ho, Brandon, Li, Jiani et al. · 2023 · Nature
67. Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity
    Nicholas N. Jarjour, Elizabeth A. Schwarzkopf, Tara R. Bradstreet, Irina Shchukina, Chih‐Chung Lin, Stanley Ching‐Cheng Huang, Chin‐Wen Lai, Melissa Erin Cook, Reshma Taneja, Thaddeus S. Stappenbeck et al. · 2019 · Nature Immunology
68. ALS blood expression profiling identifies new biomarkers, patient subgroups, and evidence for neutrophilia and hypoxia
    William R. Swindell, Colin P. S. Kruse, Edward Owen List, Darlene E. Berryman, John Joseph Kopchick · 2019 · Journal of Translational Medicine
69. Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions
    Anne Richelle, Austin W.T. Chiang, Chih‐Chung Kuo, Nathan E. Lewis · 2019 · PLoS Computational Biology
70. A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
    Zhi‐Feng Miao, Mark A. Lewis, Charles J. Cho, Mahliyah Adkins-Threats, Dongkook Park, Jeffrey Wade Brown, Jing-Xu Sun, Joseph Burclaff, Susan Kennedy, Jianyun Lu et al. · 2020 · Developmental Cell
71. Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles
    Nadim Tawil, Rayhaan Bassawon, Brian Meehan, Ali Nehme, Laura Montermini, Tenzin Gayden, Nicolas De Jay, Cristiana Spinelli, Shilpa Chennakrishnaiah, Dongsic Choi et al. · 2021 · Blood Advances
72. Inhibition of UBA6 by inosine augments tumour immunogenicity and responses
    2022
73. Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses
    Meixue Duan, Doan C. Nguyen, Chester J. Joyner, Celia L. Saney, Christopher M. Tipton, Joel Andrews, Sagar Lonial, Caroline M. Kim, Ian Hentenaar, Astrid Kosters et al. · 2023 · Cell Reports
74. Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain
    Siting Gan, Danilo G. Macalinao, Sayyed Hamed Shahoei, Lin Hai Tian, Xin Jin, Harihar Basnet, Catherine Bibby, James Muller, Pranita Atri, Evan Seffar et al. · 2024 · Cancer Cell
75. Prostaglandin E2-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells
    Siwakorn Punyawatthananukool, Ryuma Matsuura, Thamrong Wongchang, Nao Katsurada, Tatsuaki Tsuruyama, Masaki Tajima, Yutaka Enomoto, Toshio Kitamura, Masahiro Kawashima, Masakazu Toi et al. · 2024 · Nature Communications
76. A cross-species proteomic map reveals neoteny of human synapse development
    Wang, Li, Pang, Kaifang, Zhou, Li, Cebrián-Silla, Arantxa, González-Granero, Susana, Wang, Shaohui, Bi, Qiuli, White, Matthew L., Ho, Brandon, Li, Jiani et al. · 2022
77. Interpretation of cancer mutations using a multiscale map of protein systems
    Zheng, Fan, Kelly, Marcus R., Ramms, Dana J., Heintschel, Marissa L., Tao, Kai, Tutuncuoglu, Beril, Lee, John J., Ono, Keiichiro, Foussard, Helene, Chen, Michael et al. · 2021 · Science
78. PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia
    Lorenz Bastian, Michael P. Schroeder, Cornelia Eckert, Cornelia Schlee, Jutta Ortiz Tanchez, Sebastian Kämpf, Dimitrios L. Wagner, Veronika Schulze, Konstandina Isaakidis, Juan José Lázaro et al. · 2019 · Leukemia
79. Polygenic architecture informs potential vulnerability to drug-induced liver injury
    Masaru Koido, Eri Kawakami, Junko Fukumura, Yui Noguchi, Momoko Ohori, Yasunori Nio, Paola Nicoletti, Guruprasad Padur Aithal, Ann K. Daly, Paul Brent Watkins et al. · 2020 · Nature Medicine
80. Longitudinal transcriptomics define the stages of myeloid activation in the living human brain after intracerebral hemorrhage
    Michael H. Askenase, Brittany A. Goods, Hannah E. Beatty, Arthur F. Steinschneider, Sofia E. Velazquez, Artem Osherov, Margaret J. Landreneau, Shaina L. Carroll, Tho B. Tran, Victor Avram et al. · 2021 · Science Immunology
81. Venn diagram analysis overestimates the extent of circadian rhythm reprogramming
    Anne Pelikan, Hanspeter Herzel, Achim Kramer, Bharath Ananthasubramaniam · 2021 · FEBS Journal
82. Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing–Assisted Multiomics Analysis
    Xuanwen Bao, Qiong Li, Jinzhang Chen, Diyu Chen, Chanqi Ye, Xiaomeng Dai, Yanfang Wang, Xin Li, Xiaoxiang Rong, Fei Cheng et al. · 2022 · Cancer Immunology Research
83. GREM1 is required to maintain cellular heterogeneity in pancreatic cancer
    Linxiang Lan, Theodore Evan, Huafu Li, Aasia Hussain, E. Josue Ruiz, May Zaw Thin, Rute M. M. Ferreira, Hari PS, Eva Madi Riising, Yoh Zen et al. · 2022 · Nature
84. Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma
    Philip Schmassmann, Julien Roux, Alicia Buck, Nazanin Tatari, Sabrina A. Hogan, Jinyu Wang, Natália Rodrigues Mantuano, Ronja Wieboldt, Sohyon Lee, Berend Snijder et al. · 2023 · Science Translational Medicine
85. Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
    Shikhar Sharma, Chi‐Yeh Chung, Sean A. Uryu, Jelena Petrovic, Joan Q. Cao, Amanda J. Rickard, Nataliya Nady, Samantha E. Greasley, Eric Johnson, Oleg Brodsky et al. · 2023 · Cell chemical biology
86. Exploring background mutational processes to decipher cancer genetic heterogeneity
    Alexander Goncearenco, Stephanie L. Rager, Minghui Li, Qing‐Xiang Amy Sang, Igor B. Rogozin, Anna R. Panchenko · 2017 · Nucleic Acids Research
87. Association between fetal exposure to phthalate endocrine disruptor and genome-wide DNA methylation at birth
    Chung–Hsing Chen, Shih Sheng Jiang, I‐Shou Chang, Hui‐Ju Wen, Chien-Wen Sun, Shu‐Li Wang · 2018 · Environmental Research
88. Rational optimization of a transcription factor activation domain inhibitor
    Basu, Shaon, Martínez-Cristóbal, Paula, Frigolé-Vivas, Marta, Pesarrodona, Mireia, Lewis, Michael, Szulc, Elzbieta, Bañuelos, C. Adriana, Sánchez-Zarzalejo, Carolina, Bielskutė, Stasė, Zhu, Jiaqi et al. · 2023 · Nature Structural & Molecular Biology
89. Alveolar Macrophage Transcriptional Programs Are Associated with Outcomes in Acute Respiratory Distress Syndrome
    Eric D. Morrell, Pavan K. Bhatraju, Carmen R. Mikacenic, Frank Radella, Anne M. Manicone, Renee D. Stapleton, Mark M. Wurfel, Sina A. Gharib · 2019 · American Journal of Respiratory and Critical Care Medicine
90. Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration
    Das, Sudeshna, Li, Zhaozhi, Noori, Ayush, Hyman, Bradley T., Serrano-Pozo, Alberto · 2020 · Journal of Neuroinflammation
91. CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model
    I‐Li Tan, Raquel Duque do Nascimento Arifa, Harikrishna Rallapalli, Veronika Kana, Zhimin Lao, Reeti Mayur Sanghrajka, Nermin Sumru Bayin, Antoine J. Tanne, Alexandre Wojcinski, Andrey Korshunov et al. · 2020 · Oncogene
92. Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation
    Zeyu Wang, Guan-Hua Su, Ziyu Dai, Ming Meng, Hao Zhang, Fan Fan, Zhengzheng Liu, Longbo Zhang, Nathaniel Weygant, Fengqiong He et al. · 2021 · Cell Proliferation
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