Prediction equations for body composition of children and adolescents aged 8-19 years in Uganda using deuterium dilution as the reference technique.

Ndagire, Catherine T.; Muyonga, John H.; Odur, Benard; Nakimbugwe, Dorothy

doi:10.1016/j.clnesp.2018.09.004

Cited by 11Body Composition Measurement TechniquesObesity, Physical Activity, DietHuman Health and Disease

Prediction equations for body composition of children and adolescents aged 8-19 years in Uganda using deuterium dilution as the reference technique.

Ndagire, Catherine T., Muyonga, John H., Odur, Benard, Nakimbugwe, Dorothy·2018·Clinical Nutrition ESPEN

DOI 10.1016/j.clnesp.2018.09.004

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Abstract

Background and aims Body composition is important as a marker of both current and future health status. Bioelectrical impedance analysis (BIA) is a simple and accurate method for estimating body composition in field, clinical and research settings, if standard protocol procedures are followed. However, BIA requires population-specific equations since applicability of existing equations to diverse populations has been questioned. This study aimed to derive predictive equations for Total Body Water (TBW), Fat Free Mass (FFM) and Fat Mass (FM) determinations with BIA and anthropometric measurements in a population of children and adolescents aged 8-19 years in Uganda.Methods A cross-sectional study was conducted among 203 children and adolescents aged 8-19 years attending schools in Kampala district (also referred to as Kampala city since the city is conterminous with the district), Uganda through a two-stage cluster sample design. Deuterium dilution method (DDM) was used as the reference measure while BIA and anthropometric measures were used to create the new body composition prediction equations through multivariate regression.Results The new prediction equations explained 88%, 87% and 71% of the variance in TBW, FFM % and of FM respectively with no statistical shrinkage upon cross-validation. The linear regression models proposed in this study were well adjusted with respect to TBW, FFM and FM. Log of TBW obtained by DDM = 0.0129 × Impedance index + 0.0055 × Age + 0.0049 Waist Circumference + 0.1219Ht 2 + 2.0388. Log of FFM obtained by DDM = 0.0197 × FFM obtained by BIA - 0.0181 sex code - 0.00055 × Impedance + 3.1761. Log of FM obtained by DDM = 0.0634 × FM obtained by BIA - 0.1881 sex code + 0.0252 × Weight + 0.5273.Conclusion The use of these equations for more accurate body composition assessment may facilitate identification of effective intervention strategies to prevent or combat overweight and obesity among children and adolescents. They may also assist in treatment of conditions where more accurate information on body composition measures is required.

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Multicollinearity was assessed using VIF and tolerance, with VIF < 10 or tolerance > 0.1 considered appropriate.
“If more than one variable remained in the model, and to assess multicollinearity, a variance inflation factor (VIF) and the tolerance (reciprocal of VIF) were calculated for each independent variable, and a VIF < 10 or tolerance higher than 0.1 was considered appropriate (36, 37).”
From Development and Cross-Validation of a Predictive Equation for Fat-Free Mass in Brazilian Adolescents by Bioelectrical Impedance (2022) · cites this paper as [37]
All parameters used for the proposition and cross-validation of the model confirmed their validity for the studied population.
“and all parameters used for the proposition and cross-validation of the model confirmed their validity for the studied population (15, 37–39, 57)”
From Development and Cross-Validation of a Predictive Equation for Fat-Free Mass in Brazilian Adolescents by Bioelectrical Impedance (2022) · cites this paper as [37]

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Authors: Ndagire, C. T., Muyonga, J. H., Odur, B., & Nakimbugwe, D.
Affiliations: Makerere University (UG)
Corresponding author: Ndagire, Catherine T.
ORCID: Ndagire, Catherine T.
Muyonga, John H.
Nakimbugwe, Dorothy
Venue: Clinical Nutrition ESPEN
Publisher: Elsevier BV
Published: 2018-12
Volume: 28
Pages: 103-109
ISSN: 2405-4577 (ISSN-L)
DOI: 10.1016/j.clnesp.2018.09.004
OpenAlex: W2895040266
Cited by: 11
References: 26
Citations by year: 2026: 1 · 2025: 2 · 2024: 2 · 2022: 4 · 2021: 1 · 2020: 1
FWCI: 0.34
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Clinical Nutrition ESPEN (publishedVersion)
PubMed (publishedVersion)
Funders: International Atomic Energy Agency (UGA6017)
Topics: Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Human Health and Disease
Keywords: body composition, bioelectrical impedance analysis, prediction equations, deuterium dilution, total body water, fat-free mass, fat mass, children and adolescents, anthropometry, Uganda, Kampala, obesity prevention
MeSH terms: Adolescent, Body Composition, Child, Cross-Sectional Studies, Deuterium, Female, Humans, Indicator Dilution Techniques, Male, Predictive Value of Tests, Reference Values, Uganda, Young Adult, Pediatric Obesity

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Prediction equations for body composition of children and adolescents aged 8-19 years in Uganda using deuterium dilution as the reference technique.

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