Development and cross-validation of predictive equations for fat-free mass and lean soft tissue mass by bioelectrical impedance in Brazilian women.
Abstract
Background/objectives Bioelectrical impedance is one of the most used clinical techniques to assess body composition; however, it is necessary that the available predictive equations are valid for the evaluated subjects. This study aimed to develop and cross-validate equations for fat-free mass (FFM) and lean soft tissue mass (LSTM) by bioelectrical impedance for Brazilian women, in addition to test the validity of other available equations.Subjects/methods Cross-sectional study with 222 women aged 20-59 years, randomly divided into two groups: development and cross-validation. The standard technique for assessing fat mass, FFM and LSTM was dual energy X-ray absorptiometry. Paired t test, multiple regression, and Bland-Altman plots were used to test the validity of the proposed models, as well as to perform cross-validation of the models.Results The equations derived in this study were: FFM = 16.284 + 0.442 × (Height 2/Resistance) - 0.13 × age + 0.302 × Weight - 0.121 × Waist Circumference; r 2 = 0.86; SEE = 2.32 kg; and LSTM = 14.732 + 0.427 × (Height 2/Resistance) - 0.125 × age + 0.291 × Weight - 0.115 × Waist Circumference; r 2 = 0.92; SEE = 2.29 kg. In addition, the new equation for FFM showed better agreement when compared to another equation developed for a Brazilian population.Conclusions The newly developed equations provide a valid FFM and LSTM estimation and are recommended for Brazilian women with similar characteristics.
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In Brazil, two previous studies have developed equations to estimate FFM of men and women aged 20-59 years with high validity using DXA as a reference technique.
“In addition, in Brazil, two previous studies have developed equations to estimate the FFM of men (16) and women (17) aged 20–59 years, with high validity, using DXA as a reference technique.”
From Development and Cross-Validation of a Predictive Equation for Fat-Free Mass in Brazilian Adolescents by Bioelectrical Impedance (2022) · cites this paper as [17]
Reproducibility of BIA measurements was calculated in a previous study with 46 women, yielding CV of 0.17% and 0.72% for R and Xc, and TEM of 0.76 Ω (0.22%) and 0.35 Ω (0.92%) for R and Xc.
“To verify the quality of the measurements obtained by the equipment, reproducibility was calculated in a previous study with 46 women from the northeast region of Brazil. The results obtained were a coefficient of variation (CV) of 0.17 and 0.72% for R and Xc, respectively, and a technical error of measurement (TEM) of 0.76 Ω (0.22%) and 0.35 Ω (0.92%) for R and Xc, respectively (17).”
From Development and Cross-Validation of a Predictive Equation for Fat-Free Mass in Brazilian Adolescents by Bioelectrical Impedance (2022) · cites this paper as [17]
Many BIA devices do not refer to the predictive equations available in their software.
“In addition, many BIA devices do not refer to the predictive equations available in their software (17).”
From Development and Cross-Validation of a Predictive Equation for Fat-Free Mass in Brazilian Adolescents by Bioelectrical Impedance (2022) · cites this paper as [17]
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- Authors
- Costa, R. F. D., Masset, K. V. D. S. B., Silva, A. M., Cabral, B. G. D. A. T., & Dantas, P. M. S.
- Affiliations
- Universidade Federal do Rio Grande do Norte (BR)
- University of Lisbon (PT)
- Corresponding author
- Costa, Roberto Fernandes da
- Venue
- European Journal of Clinical Nutrition
- Published
- 2021-07-06
- Volume
- 76
- Issue
- 2
- Pages
- 288-296
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W3181199369
- Cited by
- 16
- References
- 50
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 1
- FWCI
- 1.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrical and Bioimpedance Tomography
- Keywords
- bioimpedance, fat-free mass, lean soft tissue mass, prediction equations, body composition, women, Brazilian women, equation validation, dual-energy X-ray absorptiometry
- MeSH terms
- Adult, Body Composition, Brazil, Cross-Sectional Studies, Female, Humans, Middle Aged, Reproducibility of Results, Absorptiometry, Photon, Body Mass Index, Electric Impedance, Young Adult
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