Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates

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Small Molecule Modulators of AMP-Activated Protein Kinase (AMPK) Activity and Their Potential in Cancer Therapy

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Adaptation of rat fast‐twitch muscle to endurance activity is underpinned by changes to protein degradation as well as protein synthesis

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VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney

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Mechanisms Behind Pyrroloquinoline Quinone Supplementation on Skeletal Muscle Mitochondrial Biogenesis: Possible Synergistic Effects with Exercise

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Mass Spectrometry-Based Proteomic Technology and Its Application to Study Skeletal Muscle Cell Biology

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It's well and truly time to stop stating that AMPK regulates glucose uptake and fat oxidation during exercise

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Trans-omic Analysis Reveals ROS-Dependent Pentose Phosphate Pathway Activation after High-Frequency Electrical Stimulation in C2C12 Myotubes

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β‐Catenin is required for optimal exercise‐ and contraction‐stimulated skeletal muscle glucose uptake

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A deep analysis of the proteomic and phosphoproteomic alterations that occur in skeletal muscle after the onset of immobilization

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Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise

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A primer on global molecular responses to exercise in skeletal muscle: Omics in focus

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Improving Phosphoproteomics Profiling Using Data-Independent Mass Spectrometry

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AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

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Profiling of human lymphocytes reveals a specific network of protein kinases modulated by endurance training status

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Temporal dynamics of the multi-omic response to endurance exercise training across tissuesPreprint

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Diurnal Differences in Human Muscle Isometric Force In Vivo Are Associated with Differential Phosphorylation of Sarcomeric M-Band Proteins

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Protocol for the processing and downstream analysis of phosphoproteomic data with PhosR

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Transient changes to metabolic homeostasis initiate mitochondrial adaptation to endurance exercise

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From workout to molecular switches: How does skeletal muscle produce, sense, and transduce subcellular redox signals?

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Exercise Improves Heart Function after Myocardial Infarction: The Merits of AMPK

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The Mitochondrial Proteomic Signatures of Human Skeletal Muscle Linked to Insulin Resistance

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Kinome Profiling Reveals Abnormal Activity of Kinases in Skeletal Muscle From Adults With Obesity and Insulin Resistance

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Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats

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The Role of Myokines in Liver Diseases

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Autophagy and Exercise: Current Insights and Future Research Directions

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Single-Cell Transcriptomics Identifies Pituitary Gland Changes in Diet-Induced Obesity in Male Mice

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Functional phosphorylation sites in cardiac myofilament proteins are evolutionarily conserved in skeletal myofilament proteins

Gross, S. M., & Lehman, S. L. (2016) · Physiological Genomics · doi:10.1152/physiolgenomics.00112.2015 · Cited by 10

Alterations of Lysine Acetylation Profile in Murine Skeletal Muscles Upon Exercise

Liang, D., Chen, C., Huang, S. M., Liu, S., Fu, L., & Niu, Y. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.859313 · Cited by 10

A modular mathematical model of exercise-induced changes in metabolism, signaling, and gene expression in human skeletal musclePreprint

Akberdin, I. R., Kiselev, I. N., Pintus, S. S., Sharipov, R. N., Vertyshev, A. Y., Vinogradova, O. L., Popov, D. V., & Kolpakov, F. A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.05.31.446385 · Cited by 9

The mitochondrial multi-omic response to exercise training across tissuesPreprint

Amar, D., Gay, N. R., Jimenez‐Morales, D., Beltran, P. M. J., Ramaker, M. E., Raja, A. N., Zhao, B., Sun, Y., Marwaha, S., Gaul, D. A., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.13.523698 · Cited by 10

Metabolic Flexibility and Mechanical Efficiency in Women Over-60

Blasco-Lafarga, C., Monferrer-Marín, J., Roldán, A., Monteagudo, P., & Chulvi‐Medrano, I. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.869534 · Cited by 9

In-depth phosphoproteomic profiling of the insulin signaling response in heart tissue and cardiomyocytes unveils canonical and specialized regulation

Achter, J. S., Torres-Vega, E., Sorrentino, A., Kahnert, K., Galsgaard, K. D., Hernández-Varas, P., Wierer, M., Holst, J. J., Wojtaszewski, J. F. P., Mills, R. W., et al. (2024) · Cardiovascular Diabetology · doi:10.1186/s12933-024-02338-4 · Cited by 9

Prospective Intervention Strategies Between Skeletal Muscle Health and Mitochondrial Changes During Aging

Zhang, X., Liao, S., Huang, L., & Wang, J. (2024) · Advanced Biology · doi:10.1002/adbi.202400235 · Cited by 11

Measurement of skeletal muscle glucose uptake in mice in response to acute treadmill running

Møller, L. L. V., Raun, S. H., Fritzen, A. M., & Sylow, L. (2022) · Journal of Biological Methods · doi:10.14440/jbm.2022.385 · Cited by 9

Affinity Purification-Mass Spectrometry and Single Fiber Physiology/Proteomics Reveals Mechanistic Insights of C18ORF25

Ng, Y., Blazev, R., McNamara, J. W., Dutt, M., Molendijk, J., Porrello, E. R., Elliott, D. A., & Parker, B. L. (2024) · Journal of Proteome Research · doi:10.1021/acs.jproteome.3c00716 · Cited by 9

Identifying Novel Signaling Pathways: An Exercise Scientists Guide to Phosphoproteomics

Wilson, G. M., Blanco, R., Coon, J. J., & Hornberger, T. A. (2018) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000146 · Cited by 9

Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle

Knudsen, J. R., Persson, K. W., Meister, J., Carl, C. S., Raun, S. H., Andersen, N. R., Sylow, L., Kiens, B., Jensen, T. E., Richter, E. A., et al. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00389.2021 · Cited by 9

Greater Phosphorylation of AMPK and Multiple AMPK Substrates in the Skeletal Muscle of 24-Month-Old Calorie Restricted Compared to Ad-Libitum Fed Male Rats

Zheng, A., Kwak, S. E., Birk, J. B., Arias, E. B., Thorley, D., Wojtaszewski, J. F. P., & Cartee, G. D. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac218 · Cited by 9

A link between mitochondrial damage and the immune microenvironment of delayed onset muscle soreness

Li, Z., Peng, L., Sun, L., & Si, J. (2023) · BMC Medical Genomics · doi:10.1186/s12920-023-01621-9 · Cited by 8

Association between “cluster of differentiation 36 (CD36)” and adipose tissue lipolysis during exercise training: a systematic review

Ouali, E. M. E., Bosquet, L., Elgharbaoui, B., Laziri, F., Laher, I., Hackney, A. C., Ibrahimi, A., Taïb, B., Harane, S. E., Weiss, K., et al. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1256440 · Cited by 9

Global scientific trends in research of epigenetic response to exercise: A bibliometric analysis

Wu, H., Hu, Y., Jiang, C. H., & Chen, C. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e25644 · Cited by 8

Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions

Loro, E., Jang, C., Quinn, W. J., Baur, J. A., Arany, Z. P., & Khurana, T. S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01439 · Cited by 8

Multiomics Approach Reveals an Important Role of BNIP3 in Myocardial Remodeling and the Pathogenesis of Heart Failure with Reduced Ejection Fraction

Chaanine, A. H., Higgins, L., Lauterboeck, L., Markowski, T. W., Yang, Q., & Delafontaine, P. (2022) · Cells · doi:10.3390/cells11091572 · Cited by 9

Phosphoproteomics Profiling Defines a Target Landscape of the Basophilic Protein Kinases AKT, S6K, and RSK in Skeletal Myotubes

Fricke, A. L., Mühlhäuser, W. W. D., Reimann, L., Zimmermann, J. P., Reichenbach, C., Knapp, B. L., Peikert, C. D., Heberle, A. M., Faessler, E., Schäuble, S., et al. (2023) · Journal of Proteome Research · doi:10.1021/acs.jproteome.2c00505 · Cited by 8

Physical Activity, Cardiorespiratory Fitness, and the Diabetes Spectrum

Nylén, E., & Kokkinos, P. F. (2019) · Springer eBooks · doi:10.1007/978-3-030-04816-7_11 · Cited by 8

Proteomic Analysis of the Functional Inward Rectifier Potassium Channel (Kir) 2.1 Reveals Several Novel Phosphorylation Sites

Brown, K. A., Anderson, C. L., Reilly, L., Sondhi, K., Ge, Y., & Eckhardt, L. L. (2021) · Biochemistry · doi:10.1021/acs.biochem.1c00555 · Cited by 7

CD47-blocking antibody confers metabolic benefits against obesity

Su, Y., Sun, J., Li, X., Huang, F., Kong, Y., Chen, Z., Zhang, J., Qin, D., Chen, X., Wang, Z., et al. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102089 · Cited by 7

Emerging roles for estrogen in regulating skeletal muscle physiology

Coyle‐Asbil, B., Ogilvie, L. M., & Simpson, J. A. (2023) · Physiological Genomics · doi:10.1152/physiolgenomics.00158.2022 · Cited by 7

Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry

Nelson, M. E., Parker, B. L., Burchfield, J. G., Hoffman, N. J., Needham, E. J., Cooke, K. C., Naim, T., Sylow, L., Ling, N. X. Y., Francis, D., et al. (2019) · The EMBO Journal · doi:10.15252/embj.2019102578 · Cited by 81

Exercise-Regulated Mitochondrial and Nuclear Signalling Networks in Skeletal Muscle

Reisman, E. G., Hawley, J. A., & Hoffman, N. J. (2024) · Sports Medicine · doi:10.1007/s40279-024-02007-2 · Cited by 57

Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function

Blazev, R., Carl, C. S., Ng, Y., Molendijk, J., Voldstedlund, C. T., Zhao, Y., Xiao, D., Kueh, A. J., Miotto, P. M., Haynes, V. R., et al. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.07.003 · Cited by 113

Shared and unique phosphoproteomics responses in skeletal muscle from exercise models and in hyperammonemic myotubes

Welch, N., Singh, S. S., Musich, R. J., Mansuri, M. S., Bellar, A., Mishra, S., Chelluboyina, A. K., Sekar, J., Attaway, A. H., Li, L., et al. (2022) · iScience · doi:10.1016/j.isci.2022.105325 · Cited by 6

Metabolism: One step forward for exercise

Hawley, J. A., & Krook, A. (2016) · Research Bank (Australian Catholic University)