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Autophagy and Tumor Metabolism
Open accessAbstract
Autophagy is a critical cellular process that generally protects cells and organisms from stressors such as nutrient deprivation. In addition to its role in normal physiology, autophagy plays a role in pathological processes such as cancer. Indeed, there has been substantial work exploring the complex and context-dependent role of autophagy in cancer. One of the emerging themes is that in certain cancer types, autophagy is important to support tumor growth; therefore, inhibiting autophagy as a therapeutic approach is actively being tested in clinical trials. A key mechanism of how autophagy promotes the growth and survival of various cancers is its ability to support cellular metabolism. The diverse metabolic fuel sources that can be produced by autophagy provide tumors with metabolic plasticity and can allow them to thrive in what can be an austere microenvironment. Therefore, understanding how autophagy can fuel cellular metabolism will enable more effective combinatorial therapeutic strategies.
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“Autophagy is upregulated in KRAS mutant cancer cells and it serves as a cell survival mechanism when cancer cells experience metabolic stress (97).”
From KRAS mutation in pancreatic cancer (2021) · cites this paper as [97]
In the citing paper
“Autophagy is upregulated in KRAS mutant cancer cells and it serves as a cell survival mechanism when cancer cells experience metabolic stress (97).”
From KRAS mutation in pancreatic cancer (2021) · cites this paper as [97]
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“According to a recurrent scenario, once a potentially tumorigenic clone has emerged, autophagy must be (re)activated to improve cellular fitness and to facilitate the transition to full-blown malignancy.164”
From Meta-hallmarks of aging and cancer (2023) · cites this paper as [164]
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Cites
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009) · Science · doi:10.1126/science.1160809 · Cited by 16,197
The emerging hallmarks of cancer metabolism
Pavlova, N. N., & Thompson, C. B. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2015.12.006 · Cited by 5,926 · cited 1×
“…A uthor M anuscript A uthor M anuscript A uthor M anuscript Metabolism and Cancer It has long been known that cancers have altered metabolism to help meet the needs of cells that have the potential for unconstrained proliferation (Pavlova and Thompson, 2016; Vander Heiden and DeBerardinis, 2017).”
BackgroundAutophagy: process and functionPreprint
Mizushima, N. (2007) · Genes & Development · doi:10.1101/gad.1599207 · Cited by 4,104
Levine, B., & Klionsky, D. J. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00099-1 · Cited by 3,728
Induction of autophagy and inhibition of tumorigenesis by beclin 1
Liang, X. H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H., & Levine, B. (1999) · Nature · doi:10.1038/45257 · Cited by 3,347
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
Mihaylova, M. M., & Shaw, R. J. (2011) · Nature Cell Biology · doi:10.1038/ncb2329 · Cited by 2,923
Understanding the Intersections between Metabolism and Cancer Biology
Heiden, M. G. V., & DeBerardinis, R. J. (2017) · Cell · doi:10.1016/j.cell.2016.12.039 · Cited by 2,369
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
Qu, X., Yu, J., Bhagat, G., Furuya, N., Hibshoosh, H., Troxel, A., Rosen, J., Eskelinen, E.-L., Mizushima, N., Ohsumi, Y., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci20039 · Cited by 2,311
MTOR: a pharmacologic target for autophagy regulation
Kim, Y. C., & Guan, K.-L. (2015) · Journal of Clinical Investigation · doi:10.1172/jci73939 · Cited by 2,126
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Zhang, M. Y., Călin, G. A., Yuen, K., Jin, D., & Chim, C. S. (2020) · Clinical Epigenetics · doi:10.1186/s13148-020-00926-1 · Cited by 21
Wang, G., Wang, Y.-Z., Yu, Y., Yin, P., Xu, K., & Zhang, H. (2021) · Integrative Cancer Therapies · doi:10.1177/15347354211017219 · Cited by 22
Yang, Q., Qiu, X., Zhang, X., Yu, Y., Li, N., Wei, X., Feng, G., Li, Y., Zhao, Y., & Wang, R. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c00870 · Cited by 21
Zhang, N., Xue, M., Sun, T., Yang, J., Pei, Z., & Qin, K. (2021) · Nutrition and Cancer · doi:10.1080/01635581.2021.1973045 · Cited by 21
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García-Miranda, A., Montes-Alvarado, J. B., Sarmiento-Salinas, F. L., Vallejo‐Ruiz, V., Castañeda-Saucedo, E., Navarro‐Tito, N., & Maycotte, P. (2024) · Scientific Reports · doi:10.1038/s41598-024-51406-y · Cited by 22
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Lu, X., Xue, C., Dong, J., Zhang, Y., & Gao, F. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb00008k · Cited by 22
Song, L., Niu, Y., Chen, R., Ju, H., Liu, Z., Zhang, B., Xie, W., & Gao, Y. (2024) · Marine Drugs · doi:10.3390/md22070316 · Cited by 20
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Schläfli, A. M., Isakson, P., Garattini, E., Simonsen, A., & Tschan, M. P. (2017) · Scientific Reports · doi:10.1038/s41598-017-12734-4 · Cited by 21
Qu, Y. Q., Gordillo-Martínez, F., Law, B. Y. K., Han, Y. K., Wu, A., Wu, J., Lam, W. K., Ho, C., Mok, S. W. F., He, H. Q., et al. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0397-0 · Cited by 21
Cervantes-Gomez, F., Stellrecht, C. M., Ayres, M., Keating, M. J., Wierda, W. G., & Gandhi, V. V. (2019) · Oncotarget · doi:10.18632/oncotarget.26876 · Cited by 20
Ammanathan, V., Vats, S., Abraham, I. M., & Manjithaya, R. R. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.02.015 · Cited by 21
Wang, N., Muhetaer, G., Zhang, X., Yang, B., Wang, C., Zhang, Y., Wang, X., Zhang, J., Wang, S., Zheng, Y., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.591400 · Cited by 20
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Qi, Y., Chen, L., Guo, L., Cao, Y., Wang, H., Yang, Y., Lu, Y., & Zhu, H. (2020) · Applied Materials Today · doi:10.1016/j.apmt.2020.100877 · Cited by 20
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Yang, H., Han, M., & Li, H. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00707 · Cited by 18
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Chen, W., Huang, F., Huang, J., Li, Y., Peng, J., Zhuang, Y., Huang, X., Lu, L., Zhu, Z., & Zhang, S. (2021) · The Journal of Gene Medicine · doi:10.1002/jgm.3364 · Cited by 19
Yin, X., Li, W., Zhang, J., Zhao, W., Cai, H., Zhang, C., Liu, Z., Guo, Y. P., & Wang, J. (2021) · Metabolites · doi:10.3390/metabo11120811 · Cited by 18
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Yang, Y., Gomez-Jenkins, M., Marsh, T., Poillet-Perez, L., Sawant, A., Chen, L., Park, N. R., Jackson, S. R., Hu, Z. S., Alon, N., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2202016119 · Cited by 21
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Raee, P., Tan, S. C., Najafi, S., Zandsalimi, F., Low, T. Y., Aghamiri, S., Fazeli, E., Aghapour, M., Mofarahe, Z. S., Heidari, M. H., et al. (2023) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-023-01134-1 · Cited by 18
Pan, Y., Suzuki, T., Sakai, K., Hirano, Y., Ikeda, H., Hattori, A., Dohmae, N., Nishio, K., & Kakeya, H. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176156 · Cited by 18
Hwang, J., Park, A., Kim, C., Kim, C. G., Kwak, J., Kim, B., Shin, H., Ku, M., Yang, J., Baek, A., et al. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-024-01769-6 · Cited by 19
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Yan, C., Zhao, J., Yu, Q., Zhao, F., Ji, L., & Zhang, J. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11205 · Cited by 18
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Zhang, Q., Song, Q., Liu, S., Xu, Y., Gao, D., Lu, P., Liu, Y.-T., Zhao, G., Wu, L., Zhao, C., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1230772 · Cited by 18
Fontes, M. G., Silva, C., Roldán, W. H., & Monteiro, G. (2024) · Medical Oncology · doi:10.1007/s12032-024-02424-3 · Cited by 18
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Yang, D., Zhang, Y., Lei, J., Li, S., He, L., Tang, D., Xu, C. S., Zhang, L., Wen, J., Lin, H., et al. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114565 · Cited by 16
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Kim, D.-M., Shim, Y., Kwon, H., Kim, J., Park, J.-I., Kim, D.-H., Kim, J. H., Kim, J. H., & Jeong, Y. (2019) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2019.07.024 · Cited by 15
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Yang, C., Cui, X., Ding, Z., Jiang, T., Feng, X., Pan, Y., Lin, Y., Shang, T., Wang, Q., Pan, J., et al. (2022) · Cancer Science · doi:10.1111/cas.15593 · Cited by 14
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Metadata
- Authors
- Kimmelman, A. C., & White, E.
- Affiliations
- NYU Langone Health (US)
- Rutgers, The State University of New Jersey (US)
- Corresponding author
- Kimmelman, Alec C.
- White, Eileen
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 25
- Issue
- 5
- Pages
- 1037-1043
- ISSN
- 1550-4131 (ISSN-L)
- PMC
- PMC5604466
- OpenAlex
- W2611224317
- Cited by
- 826
- References
- 80
- Citations by year
- 2026: 37 · 2025: 58 · 2024: 99 · 2023: 88 · 2022: 109 · 2021: 150 · 2020: 112 · 2019: 95 · 2018: 61 · 2017: 17
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (R01CA157490, R01CA188048, P01CA117969)
- ACS (RSG-13-298-01-TBG)
- NIH (R01GM095567, R01CA163591, R01CA130893, R01CA188096, R01CA193970)
- Robert Wood Johnson Foundation (P30CA72720)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Autophagy in Disease and Therapy
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Hypoxia, and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- autophagy, cancer metabolism, cancer, metabolic plasticity, nutrient deprivation, autophagy inhibition, cancer therapy, tumor microenvironment, tumor growth
- MeSH terms
- Animals, Autophagy, Cell Survival, Humans, Neoplasms, Cell Proliferation, Metabolic Networks and Pathways, Tumor Microenvironment
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