A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

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Items 301–400 of 515

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    Keila N. Miles, Matthew R. Skelton · 2020 · Brain Research
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    Zeyu Zhou, Jocelyn Vidales, José Antonio González-Reyes, Bradley Shibata, Keith Baar, Jennifer M. Rutkowsky, Jon Jay Ramsey · 2021 · Nutrients
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    Rio Barrere‐Cain, Patrick Allard · 2020 · Epigenetics Insights
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  16. Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer
    Chase Garcia, Ariana Banerjee, Claire B. Montgomery, Lauren Adcock, Izumi Maezawa, Jon Jay Ramsey, Ana Cristina Grodzki, Kyoungmi Kim, Gino A. Cortopassi · 2025 · Frontiers in Aging
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    Ke Li, Lian Y. Wang, Danlin Zhu, Wenhong Wang, Yifan Guo, Haoyang Gao, Muge Zhou, Weihua Xiao · 2025 · Aging Cell
  18. Effect of Caloric Restriction on Aging: Fixing the Problems of Nutrient Sensing in Postmitotic Cells?
    Моргунова Галина Васильевна, Gregory A. Shilovsky, Alexander N. Khokhlov · 2021 · Biochemistry (Moscow)
  19. The ketogenic diet: history, mechanism of action, indications and contraindications
    Е. В. Иванникова, Marina V. Altashina, Ekaterina Anatol'evna Troshina · 2021 · Problems of Endocrinology
  20. Systemic Ketone Replacement Does Not Improve Survival or Cancer Cachexia in Mice With Lung Cancer
    Henning T. Langer, Shakti Ramsamooj, Roger J. Liang, Rahul Grover, Seo‐Kyoung Hwang, Marcus DaSilva Goncalves · 2022 · Frontiers in Oncology
  21. A ketogenic diet alters mTOR activity, systemic metabolism and potentially prevents collagen degradation associated with chronic alcohol consumption in mice
    Luciano Willemse, Karin Terburgh, Roan Louw · 2023 · Metabolomics
  22. [Inhibitory effect of ketogenic diet on neuroblastoma in BALB/c-nu mouse models].
    He Jiaojiao, Linya Lü, Peng Junwei, Changchun Li, Xiangru Kong, Jun Zhang, Liang Peng · 2020 · PubMed Central
  23. Using Dictyostelium to Advance Our Understanding of the Role of Medium Chain Fatty Acids in Health and Disease
    Erwann Pain, Sonia Shinhmar, Robin S. B. Williams · 2021 · Frontiers in Cell and Developmental Biology
  24. Disentangling High Fat, Low Carb, and Healthy Aging
    Holly M. Brown‐Borg · 2017 · Cell Metabolism
  25. Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study
    Brianna J. Stubbs, Elizabeth B Stephens, Chatura Senadheera, Sawyer Peralta, Stephanie Roa Diaz, Laura E. Crotty Alexander, Wendie Silverman-Martin, Thelma Y. Garcia, Michi Yukawa, Jenifer Morris et al. · 2024 · The journal of nutrition health & aging
  26. Generalized Ketogenic Diet Induced Liver Impairment and Reduced Probiotics Abundance of Gut Microbiota in Rat
    Ge Song, Dan Song, Yongwei Wang, Li Wang, Weiwei Wang · 2024 · Biology
  27. Sex Differences in Ketogenic Diet Response Reveal Gonadal Hormone Interaction With FGF21 in Mice
    Yuan Zhang, Jesse D. Cochran, Rhonda Souvenir, Warren C. Tai, Ruiyou Xia, Brendan S Gladwin, Natalie B Barton, Renata Oliveira Pereira, E. Dale Abel · 2025 · Journal of the Endocrine Society
  28. Obesity as a Systems‐Level Driver of Cancer: Mechanisms and Nutritional Reprogramming
    Camelia Munteanu, Danny N. Dhanasekaran · 2025 · Obesity Reviews
  29. Insights into the therapeutic strategies for aging and aging-associated diseases
    Ruifang Dong, Qiming Wu, Juntao Kan, Caili Fu, Vincenzo Sorrentino, Ashley Chow, Yanan Lei, Di Wu, Zhenzhen Xu, Jun Du et al. · 2026 · Signal Transduction and Targeted Therapy
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  32. Effect of ketogenic diets on insulin-like growth factor (IGF)-1 in humans: A systematic review and meta-analysis
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  33. The anti-senescence effect of D-β-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway
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  60. Exploring the Impact of Ketogenic Diet and Intermittent Fasting on Male Rats’ Testicular Health: An Analysis of Hormonal Regulation, Oxidative Stress, and Spermatogenesis
    Hilal Üstündağ, Songül Doğanay, Büşra Öztürk, Fadime Köse, Nezahat Kurt, Nevra Aydemi̇r Celep, Mehmet Tahir Huyut, Fatma Betül Özgeriş · 2023 · Journal of Food Biochemistry
  61. In silico clinical trials for anti-aging therapies
    Javier Abel Menéndez, Elisabet Cuyàs, Núria Folguera-Blasco, Sara Verdura, Begoña Martı́n-Castillo, Jorge Joven, Tomás Alarcón · 2019 · Aging
  62. Dietary restriction in senolysis and prevention and treatment of disease
    Sepideh Aminzadeh-Gohari, Barbara Kofler, Chiara Maria Stella Herzog · 2022 · Critical Reviews in Food Science and Nutrition
  63. Nutritional Regulation of Mitochondrial Function
    Goutham Vasam, Kimberly Reid, Yan Burelle, Keir J. Menzies · 2019 · Elsevier eBooks
  64. Anti-ageing effects of protein restriction unpacked
    Cristal M. Hill, Matt R. Kaeberlein · 2021 · Nature
  65. Ketosis versus carbotoxicity – metabolism determines the outcome of cancer immunotherapy
    Aitziber Buqué, Lorenzo Galluzzi, Guido Kroemer · 2021 · Molecular & Cellular Oncology
  66. Overcome Prostate Cancer Resistance to Immune Checkpoint Therapy with Ketogenic Diet-Induced Epigenetic Reprogramming
    Sean Patrick Murphy, Sharif Rahmy, Dailin Gan, Yini Zhu, Maxim Manyak, Jun Li, Xuemin Lu, Xin Lü · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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    José Augusto Nogueira-Machado, Fabiana Rocha-Silva, Nathália Augusta Gomes · 2025 · Biomedicines
  68. Exercise-induced β-hydroxybutyrate contributes to cognitive improvement in aging mice
    Lian Wang, Liwei Mao, Danlin Zhu, Ke Li, Haoyang Gao, Muge Zhou, Jiabin Wu, Dan Yang, Ze Wang, Wenhong Wang et al. · 2025 · Journal of sport and health science/Journal of Sport and Health Science
  69. Regulation of autophagy‐mediated pathways by diet, physical activity, and sleep in Alzheimer's disease
    Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M. A. D. Binosha Fernando, Belinda M. Brown, Samantha L. Gardener, Stephanie Ruth Rainey‐Smith, Ralph Nigel Martins, Prashant Bharadwaj · 2026 · Alzheimer s & Dementia
  70. Mechanisms and interventions of epigenetic aging
    Qingqing Chu, Yihang Li, Zeming Wu, Jing Tao Qu, Guang‐Hui Liu · 2026 · Cell chemical biology
  71. Nicotinamide riboside functions during development while beta-hydroxybutyrate functions during adulthood to extend C. elegans lifespan
    Jeffery Dylan Peters, McKenzie P Peters, Patrick C. Bradshaw · 2023 · PubMed Central
  72. [Ketone Body Metabolism and Renal Diseases].
    Ying Liu, Liang Ma, Ping Fu · 2023 · 四川大学学报:医学版
  73. Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesity
    Sarah E. Deemer, Brandon M. Roberts, Daniel L. Smith, Eric P. Plaisance, Andrew Philp · 2024 · American Journal of Physiology-Cell Physiology
  74. Low‐Carbohydrate Diet Exacerbates Denervation‐Induced Atrophy of Rat Skeletal Muscle Under the Condition of Identical Protein Intake
    Aki Yokogawa, Kohei Kido, Ikuru Miura, Eisuke Oyama, Daisuke Takakura, Keigo Tanaka, Daniel James Wilkinson, Kenneth Smith, Philip James Atherton, Kentaro Kawanaka · 2025 · Journal of Cachexia Sarcopenia and Muscle
  75. Improvement in age-related cognitive functions and life expectancy by ketogenic diets
    Arne Vernon Astrup, Mads F. Hjorth · 2017 · Nature Reviews Endocrinology
  76. Anti-inflammatory and Anti-infectious Dietary Paradigms May Be Crucial for Visceral Weight Reduction
    Dongmei Chen, Meng-Le Zhang, Zhuqing Shi, Changqing Li, Qi Wang, Jianping Song, Qin Xu, He Li, Qing-Ping Zeng · 2019 · Frontiers in Immunology
  77. Integration of immune-metabolic signals to preserve healthy aging
    Emily L. Goldberg · 2020 · Translational Medicine of Aging
  78. Bridging the Gap: A Geroscience Primer for Neuroscientists With Potential Collaborative Applications
    Jessica M. Hoffman, Caesar M. Hernandez, Abbi R. Hernandez, Jennifer L. Bizon, Sara N. Burke, Christy S. Carter, Thomas W. Buford · 2021 · The Journals of Gerontology Series A
  79. Metabolomics Study of Isocaloric Different Dietary Patterns on the Life Span in Healthy Population
    Cong Zhang, Qingna Yan, Qiushuang Zhu, Jinxiao Liu, Yuanjie Dong, Yuqiao Li, Ruohua Wang, Xuanfeng Tang, Xinyi Lv, Xiaoqing Li et al. · 2021 · Clinical Interventions in Aging
  80. Rapamycin and rapalogs
    Dudley W. Lamming · 2023 · Elsevier eBooks
  81. Dietary ingredients inducing cellular senescence in animals and humans: A systematic review
    Lihuan Guan, Kristina Zdantsevich, Elena Sandalova, Karen Crasta, Andrea Britta Maier · 2025 · Mechanisms of Ageing and Development
  82. Nutritional strategies against skeletal muscle wasting in cancer-associated cachexia: the role of β-hydroxybutyrate and polyunsaturated fatty acids
    Benjamin Hay, Aurélien Brun, Anne Fougerat, Vera Christine Mazurak, Olivier Le Bacquer, Jérémie Talvas, Frédéric Capel · 2025 · Translational Oncology
  83. Changing chronomics of clock, immune and Parkinson’s disease-associated genes in SCN and SN with aging in male Wistar rats: ketogenic diet intervention
    Sushree Abhidhatri Sharma, Anita Jagota · 2025 · Biogerontology
  84. Leveraging cancer metabolism to translate into effective therapeutics
    Jie Xu, Linlin Guo, Yi Wang, Xiaoping Li, Ping Yi, Chunming Cheng · 2025 · Seminars in Cancer Biology
  85. Dietary Walnuts Preserve Aspects of Health Span and Alter the Hippocampal Lipidome in Aged High-Fat Diet-Fed Mice
    Ardijana Novaj, Matthew G. Engel, Ruixuan Wang, Kai Mao, Xiaonan Xue, Yam Amir, Gil Atzmon, Derek M. Huffman · 2023 · International Journal of Molecular Sciences
  86. Genetics and diet shape the relationship between islet function and whole body metabolism
    Belinda Yau, Søren Madsen, Marin E. Nelson, Kristen C. Cooke, Andreas Mæchel Fritzen, Ida Holte Thorius, Jacqueline Stöckli, David Ernest James, Melkam Alamerew Kebede · 2024 · American Journal of Physiology-Endocrinology and Metabolism
  87. The genetic advantage of healthy centenarians: unraveling the central role of NLRP3 in exceptional healthspan
    Stefan F. F. Verlinden · 2024 · Frontiers in Aging
  88. Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms
    Brianna J. Stubbs, Gabriela Alvarez Azañedo, Sawyer Peralta, Stephanie Roa Diaz, Wyatt Gray, Laura E. Crotty Alexander, Wendie Silverman-Martin, Thelma Y. Garcia, Traci M. Blonquist, Vaibhav Upadhyay et al. · 2024 · PLoS ONE
  89. Metabolic Changes and Their Characterization
    Noor-ul Ain, Hira Gull · 2020 · Springer eBooks
  90. Modestly Increased Incidence of Ketosis in Caloric Restriction Does not Significantly Alter the Effects of Caloric Restriction
    Bradley S. Ferguson, P. Sahoo, Erin McGrail, A. Francois, Matthew S. Stratton · 2022 · The journal of nutrition health & aging
  91. dNAGLU Extends Life Span and Promotes Fitness and Stress Resistance in Drosophila
    Rubing Xue, Ke Yang, Fu‐Hui Xiao, Liping Yang, Guijun Chen, Yongxuan Li, Yunshuang Ye, Kangning Chen, Sheryl T. Smith, Gong‐Hua Li et al. · 2022 · International Journal of Molecular Sciences
  92. Evaluating the efficacy of a ketogenic diet in managing drug resistant paediatric DEDPC5-related epilepsy.
    A. Winczewska-Wiktor, Małgorzata Braszka, Mia Harada-Laszlo, M. Badura-Stronka, I. Kaczmarek, Monika Starczewska, Agnieszka Wencel-Warot, Barbara Steinborn, Aleksander Jamsheer · 2023 · Epilepsy & Behavior
  93. Nutritional strategies cause memory damage and alter biochemical parameters without causing neuroinflammation
    Keila Rufatto de Souza, Nicole Alessandra Engel, Hevylin Jacinto Soares, Catarina Barbosa Chaves Bressan, Larissa Marques Dela Vedova, Larissa Espindola da Silva, Talita Farias Mendes, Mariella Reinol da Silva, Mariana Pacheco de Oliveira, Amanda Indalécio Goulart et al. · 2024 · Metabolic Brain Disease
  94. Possible Involvement of Hippocampal miR‐539‐3p/Lrp6/Igf1r Axis for Diminished Working Memory in Mice Fed a Low‐Carbohydrate and High‐Protein Diet
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  95. Sirtuins, healthspan, and longevity in mammals
    Surinder Kumar, William Giblin, David B. Lombard · 2021 · Elsevier eBooks
  96. A mechanistic perspective on the health promoting effects of alcohol – A focus on epigenetics modification
    Shou Ping Guan, Shermila N. Kumar, David Yang‐Wei Fann, Brian Keith Kennedy · 2022 · Alcohol
  97. Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms
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  98. The dietary exposome: a brief history of diet, longevity, and age-related health in rodents
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    Yongpan An, Qian Wang, Panshuang Qiao, Jihan Liu, Ang Ma, Yutong Chen, Daqian Yang, Ying Yi, Nannan Li, Feng Lu et al. · 2025 · Nutrients
  100. Sex-dependent effects of a gestational ketogenic diet on offspring birth and lifespan
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