Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States

Cites (352)

Items 201–352 of 352

1. BDNF and exercise enhance neuronal DNA repair by stimulating CREB-mediated production of apurinic/apyrimidinic endonuclease 1
   Yang, Jenq-Lin, Lin, Yu-Ting, Chuang, Pei-Chin, Bohr, Vilhelm A., Mattson, Mark P. · 2014 · NeuroMolecular Medicine
2. Unravelling the mechanisms regulating muscle mitochondrial biogenesis
   Hood, David A., Tryon, Liam D., Carter, Heather N., Kim, Yuho, Chen, Chris C.W. · 2016 · Biochemical Journal
3. Aging and motor inhibition: A converging perspective provided by brain stimulation and imaging approaches
   Oron Levin, Hakuei Fujiyama, Matthieu P. Boisgontier, Stephan Patrick Swinnen, Jeffery J. Summers · 2014 · Neuroscience & Biobehavioral Reviews
4. More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
   Lane-Donovan, Courtney, Philips, Gary T., Herz, Joachim · 2014 · Neuron
5. The Aging Motor System as a Model for Plastic Changes of GABA-Mediated Intracortical Inhibition and Their Behavioral Relevance
   Kirstin-Friederike Heise, Máximo Zimerman, Julia Hoppe, Christian P Gerloff, Karl Wegscheider, Friedhelm Christoph Hummel · 2013 · Journal of Neuroscience
6. N‐Methyl‐D‐Aspartate antagonist reduces stroke size and regional glucose metabolism
   Roger Pancoast Simon, Kazuya Shiraishi · 1990 · Annals of Neurology
7. Age-Related Changes in Axonal and Mitochondrial Ultrastructure and Function in White Matter
   Katharine E. Stahon, Chinthasagar Bastian, Shelby Griffith, Grahame J. Kidd, Sylvain Brunet, Selva Baltan · 2016 · Journal of Neuroscience
8. Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence
   Jia Yao, Ryan T. Hamilton, Enrique Cadenas, Roberta Díaz Brinton · 2010 · Biochimica et Biophysica Acta (BBA) - General Subjects
9. Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration
   Weidenheim, Karen M., Dickson, Dennis W., Rapin, Isabelle · 2009 · Mechanisms of Ageing and Development
10. Compromised white matter integrity in obesity
    Stephanie Kullmann, F. Schweizer, Ralf Veit, Andreas Fritsche, Hubert T. Preissl · 2015 · Obesity Reviews
11. Diagnosis of acute stroke
    Matthias König · 2007 · CRC Press eBooks
12. Omega-3 fatty acids and brain resistance to ageing and stress: body of evidence and possible mechanisms
    Denis, I., Potier, B., Vancassel, S., Heberden, C., Lavialle, M. · 2013 · Ageing Research Reviews
13. Intermittent fasting attenuates inflammasome activity in ischemic stroke
    David Yang‐Wei Fann, Tomislav Santro, Silvia Manzanero, Alexander Widiapradja, Yi‐Lin Cheng, Seung-Yoon Lee, Prasad Chunduri, Dong‐Gyu Jo, Alexis M. Stranahan, Mark P. Mattson et al. · 2014 · Experimental Neurology
14. Oxidative and nitrative alpha‐synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies
    Schildknecht, Stefan, Gerding, Hanne R., Karreman, Christiaan, Drescher, Malte, Lashuel, Hilal A., Outeiro, Tiago F., Di Monte, Donato A., Leist, Marcel · 2013 · Journal of Neurochemistry
15. Networks mediating the clinical effects of pallidal brain stimulation for Parkinson's disease: A PET study of resting-state glucose metabolism
    Masafumi Fukuda · 2001 · Brain
16. Characterizing cognitive aging in humans with links to animal models
    Gene E. Alexander, Lee Ryan, Dawn Bowers, Thomas C. Foster, Jennifer L. Bizon, David Geldmacher, Elizabeth Louise Glisky · 2012 · Frontiers in Aging Neuroscience
17. DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes
    Peter Sýkora, Magdalena Misiak, Yue Wang, Somnath Ghosh, Giovana da Silva Leandro, Dong Liu, Jane Y. Tian, Beverly A. Baptiste, Wei‐na Cong, Boris M. Brenerman et al. · 2014 · Nucleic Acids Research
18. Caloric Restriction in Older Adults—Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function
    Kristin Prehn, Reiner Jumpertz von Schwartzenberg, Knut Mai, Ulrike Zeitz, A. Veronica Witte, Dierk J. Hampel, Anna-Maria Szela, Sonja Fabian, Ulrike Grittner, Joachim Spranger et al. · 2016 · Cerebral Cortex
19. Evidence for a Developmental Role for TLR4 in Learning and Memory
    Eitan Okun, Boaz Barak, Ravit Madar, Sarah M. Rothman, Kathleen J. S. Griffioen, Nicholas Jason Roberts, Kamilah Castro, Mohamed R. Mughal, Mario A. Pita, Alexis M. Stranahan et al. · 2012 · PLoS ONE
20. Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes
    Shimabukuro, Marilia Kimie, Langhi, Larissa Gutman Paranhos, Cordeiro, Ingrid, Brito, José M., Batista, Claudia Maria de Castro, Mattson, Mark P., de Mello Coelho, Valeria · 2016 · Scientific Reports
21. Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro
    Lynda S. Wright, Karen R. Prowse, Kyle Wallace, Maarten H.K. Linskens, Clive N. Svendsen · 2006 · Experimental Cell Research
22. Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline
    Diane Cress Cabelof · 2003 · DNA repair
23. Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability
    Naoko Ikematsu, Mark L. Dallas, Fiona A. Ross, Ryan W. Lewis, J. Nicole Rafferty, Jonathan A. David, Rakesh Suman, Chris Peers, David Grahame Hardie, A. Mark Evans · 2011 · Proceedings of the National Academy of Sciences
24. Mitochondrial Quality Control via the PGC1α-TFEB Signaling Pathway Is Compromised by Parkin Q311X Mutation But Independently Restored by Rapamycin
    Almas Siddiqui, Dipa Bhaumik, Shankar J. Chinta, Anand Rane, Subramanian Rajagopalan, Christopher A. Lieu, Gordon J. Lithgow, Julie Kay Andersen · 2015 · Journal of Neuroscience
25. Post-Injury Administration of Mitochondrial Uncouplers Increases Tissue Sparing and Improves Behavioral Outcome following Traumatic Brain Injury in Rodents
    Pandya, Jignesh D., Pauly, James R., Nukala, Vidya N., Sebastian, Andrea H., Day, Kristen M., Korde, Amit S., Maragos, William F., Hall, Edward D., Sullivan, Patrick G. · 2007 · Journal of Neurotrauma
26. A Mechanism for the Neuroprotective Effect of Apolipoprotein E
    Ward A. Pedersen, Sic L. Chan, Mark P. Mattson · 2000 · Journal of Neurochemistry
27. Aging and large-scale functional networks: White matter integrity, gray matter volume, and functional connectivity in the resting state
    Lars Marstaller, Mark Williams, Anina N. Rich, Greg R. Savage, Hana Burianová · 2015 · Neuroscience
28. Extracellular vesicle-associated Aβ mediates trans-neuronal bioenergetic and Ca2+-handling deficits in Alzheimer’s disease models
    Eitan, Erez, Hutchison, Emmette R, Marosi, Krisztina, Comotto, James, Mustapic, Maja, Nigam, Saket M, Suire, Caitlin, Maharana, Chinmoyee, Jicha, Gregory A, Liu, Dong et al. · 2016 · npj Aging and Mechanisms of Disease
29. Hypercholesterolaemia and vascular dementia
    Jason P. Appleton, Polly Scutt, Nikola Sprigg, Philip M. Bath · 2017 · Clinical Science
30. Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease
    Simonetta Camandola, Mark P. Mattson · 2010 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
31. Reduced calcium uptake by rat brain mitochondria and synaptosomes in response to aging
    Steven W. Leslie, L. Judson Chandler, Edward M. Barr · 1985 · Brain Research
32. Upregulation of Calcium/Calmodulin-Dependent Protein Kinase IV Improves Memory Formation and Rescues Memory Loss with Aging
    Hotaka Fukushima, Ryouta Maeda, Ryousuke Suzuki, Akinobu Z. Suzuki, Masanori Nomoto, Hiroki Toyoda, Long‐Jun Wu, Hui Xu, Ming Zhao, Kenji Ueda et al. · 2008 · Journal of Neuroscience
33. Physical activity over a decade modifies age-related decline in perfusion, gray matter volume, and functional connectivity of the posterior default-mode network—A multimodal approach
    Carl‐Johan Boraxbekk, Alireza Salami, Anders Wåhlin, Lars H Nyberg · 2015 · NeuroImage
34. Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease
    Sara Sepe, Chiara Milanese, Sylvia Gabriels, Kasper Derks, César Payán‐Gómez, Wilfred F. J. van IJcken, Yvonne Rijksen, Alex L. Nigg, Sandra Moreno, Silvia Cerri et al. · 2016 · Cell Reports
35. Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress
    Han Shi, Han‐Xiang Deng, David R. Gius, Paul T. Schumacker, Dalton James Surmeier, Yongchao C. Ma · 2017 · Human Molecular Genetics
36. Neuroprotection in stroke by complement inhibition and immunoglobulin therapy
    Thiruma Valavan Arumugam, Trent M. Woodruff, Justin Durla Lathia, P.K. Selvaraj, Mark P. Mattson, Stephen M. Taylor · 2008 · Neuroscience
37. Molecular Identification of the Ischemic Penumbra
    Philip R. Weinstein, Shwuhuey M. Hong, Frank R. Sharp · 2004 · Stroke
38. A Reversible Early Oxidized Redox State That Precedes Macromolecular ROS Damage in Aging Nontransgenic and 3xTg-AD Mouse Neurons
    Debolina Ghosh, Kelsey R. LeVault, Aaron Barnett, Gregory J. Brewer · 2012 · Journal of Neuroscience
39. Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques
    Nikolaos G. Papaioannou, Peter C.J. Tooten, Anne Marie van Ederen, J. Böhl, Jaime Rofina, Thomas Tsangaris, Erik Gruys · 2001 · Amyloid
40. A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction
    Ana López, Suzee E. Lee, Kevin J. Wojta, Eliana Marisa Ramos, Eric Klein, Jason Chen, Adam L. Boxer, Maria Luisa Gorno‐Tempini, Daniel H. Geschwind, Lars Schlotawa et al. · 2017 · Brain
41. Being overweight is associated with hippocampal atrophy: the PATH Through Life Study
    Nicolas Cherbuin, Kerry A. Sargent‐Cox, Mark A. Fraser, Perminder Singh Sachdev, Kaarin Jane Anstey · 2015 · International Journal of Obesity
42. The KATP Channel Activator Diazoxide Ameliorates Amyloid-β and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease
    Dong Liu, M. G. R. PITTA, Jong-Hwan Lee, Balmiki Ray, Debomoy K. Lahiri, Katsutoshi Furukawa, Mohamed R. Mughal, Haiyang Jiang, Julissa S. Villarreal, Roy G. Cutler et al. · 2010 · Journal of Alzheimer s Disease
43. Regional cerebral glucose transport and utilization in Alzheimer's disease
    Robert Paul Friedland, William J. Jagust, R.H. Huesman, E. Koss, B Knittel, Chester A. Mathis, Beth A. Ober, Bernard M. Mazoyer, Thomas F. Budinger · 1989 · Neurology
44. Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila
    Teresa Niccoli, Melissa Cabecinha, Anna Tillmann, Fiona Kerr, Chi Tung Wong, Dalia Cardenes, Alec J. Vincent, Lucia Bettedi, Li Li, Sebastian Grönke et al. · 2016 · Current Biology
45. Perturbations of neural circuitry in aging, mild cognitive impairment, and Alzheimer's disease
    Stephanie L. Leal, Michael A. Yassa · 2013 · Ageing Research Reviews
46. Emerging Roles of CREB-Regulated Transcription Coactivators in Brain Physiology and Pathology
    Carlos A. Saura, Jean‐René Cardinaux · 2017 · Trends in Neurosciences
47. Association between waist circumference and gray matter volume in 2344 individuals from two adult community-based samples
    Deborah Janowitz, Katharina Wittfeld, Jan Terock, Harald Jürgen Freyberger, Katrin Hegenscheid, Henry Völzke, Mohamad Habes, Norbert Hosten, Nele Friedrich, Matthias A. Nauck et al. · 2015 · NeuroImage
48. Mitochondrial Metabolic Reprogramming Induced by Calorie Restriction
    Alejandro Martín‐Montalvo, Rafael de Cabo · 2012 · Antioxidants and Redox Signaling
49. Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, β-amyloid accumulation and cognitive decline in the APP/PSEN1 mouse model of Alzheimer's disease
    Jennifer M. Walker, Shilpy Dixit, Anjelica Christina Saulsberry, James Michael May, Fiona Edith Harrison · 2017 · Neurobiology of Disease
50. Regulating protein breakdown through proteasome phosphorylation
    Jordan J. S. VerPlank, Alfred Lewis Goldberg · 2017 · Biochemical Journal
51. DNA damage in the oligodendrocyte lineage and its role in brain aging
    Tse, Kai-Hei, Herrup, Karl · 2017 · Mechanisms of Ageing and Development
52. Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia
    Yazi Li, Yuying Zhang, Lei Wang, Ping Wang, Yanhong Xue, Xiaopeng Li, Xinhua Qiao, Xu Zhang, Tao Xu, Guang‐Hui Liu et al. · 2017 · Autophagy
53. Telomere shortening reduces Alzheimer’s disease amyloid pathology in mice
    Rolyan, Harshvardhan, Scheffold, Annika, Heinrich, Annette, Begus-Nahrmann, Yvonne, Langkopf, Britta Heike, Hölter, Sabine M., Vogt-Weisenhorn, Daniela M., Liss, Birgit, Wurst, Wolfgang, Lie, Dieter Chichung et al. · 2011 · Brain
54. Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging
    Anirban Paul, Amy Belton, Sanjay Nag, Ian Martin, Michael S. Grotewiel, Atanu Duttaroy · 2007 · Mechanisms of Ageing and Development
55. Oxidative Stress and Lysosomes: CNS-Related Consequences and Implications for Lysosomal Enhancement Strategies and Induction of Autophagy
    David Butler, Ben A. Bahr · 2006 · Antioxidants and Redox Signaling
56. DNP, mitochondrial uncoupling, and neuroprotection: A little dab'll do ya
    John G. Geisler, Krisztina Marosi, Joshua Halpern, Mark P. Mattson · 2016 · Alzheimer s & Dementia
57. Considerations on pig models for appetite, metabolic syndrome and obese type 2 diabetes: From food intake to metabolic disease
    S.J. Koopmans, Teun Schuurman · 2015 · European Journal of Pharmacology
58. Hippocampal Adult Neurogenesis Is Maintained by Neil3-Dependent Repair of Oxidative DNA Lesions in Neural Progenitor Cells
    Christine Elisabeth Regnell, Gunn A. Hildrestrand, Yngve Sejersted, Tirill Medin, Olve Moldestad, Veslemøy Rolseth, Silje Zandstra Krokeide, Rajikala Suganthan, Luisa Luna, Magnar Bjørås et al. · 2012 · Cell Reports
59. Nutrition, the brain and cognitive decline: insights from epigenetics
    M. J. Dauncey · 2014 · European Journal of Clinical Nutrition
60. Oxidative lipid modification of nicastrin enhances amyloidogenic γ‐secretase activity in Alzheimer’s disease
    A‐Ryeong Gwon, Jong‐Sung Park, Thiruma Valavan Arumugam, Yong‐Kook Kwon, Sic L. Chan, Seol-Hee Kim, Sang‐Ha Baik, Sung-Hee Yang, Young‐Kwang Yun, Yuri Choi et al. · 2012 · Aging Cell
61. High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task
    Alison D. McNeilly, Ritchie Williamson, Calum D. Sutherland, David J.K. Balfour, Caroline A. Stewart · 2010 · Behavioural Brain Research
62. Comparison of neuropathologic criteria for the diagnosis of Alzheimer's disease
    Geddes, J.W, Tekirian, T.L, Soultanian, N.S, Ashford, J.W, Davis, D.G, Markesbery, W.R · 1997 · Neurobiology of Aging
63. Mitochondrial biogenesis is required for axonal growth
    Annika Vaarmann, Merle Mandel, Akbar Zeb, Przemyslaw Warȩski, Joanna Liiv, Malle Kuum, Eva Antsov, Mailis Liiv, Michal Cagalinec, Vinay Choubey et al. · 2016 · Development
64. Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia
    Steven H. Graham, Hao Liu · 2016 · Ageing Research Reviews
65. Brain functional alterations in Type 2 Diabetes – A systematic review of fMRI studies
    Helen Macpherson, Melissa Formica, Elizabeth Harris, Robin M. Daly · 2017 · Frontiers in Neuroendocrinology
66. Obesity Weighs down Memory through a Mechanism Involving the Neuroepigenetic Dysregulation of Sirt1
    Frankie D. Heyward, Daniel Gilliam, Mark A. Coleman, Cristin F. Gavin, Jing Wang, Garrett A. Kaas, Richard J. Trieu, John Lewis, Jerome Moulden, J. David Sweatt · 2016 · Journal of Neuroscience
67. Ablation of TNF-RI/RII Expression in Alzheimer's Disease Mice Leads to an Unexpected Enhancement of Pathology
    Montgomery, Sara L., Mastrangelo, Michael A., Habib, Diala, Narrow, Wade C., Knowlden, Sara A., Wright, Terry W., Bowers, William J. · 2011 · The American Journal of Pathology
68. Aging-InducedNrf2-AREPathway Disruption in the Subventricular Zone Drives Neurogenic Impairment in Parkinsonian Mice viaPI3K-Wnt/β-CateninDysregulation
    Francesca L’Episcopo, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Maria C. Morale, Francesco Impagnatiello, Stefano Pluchino, Bianca Marchetti · 2013 · Journal of Neuroscience
69. Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity
    Amigo, Ignacio, Menezes‐Filho, Sergio Luiz, Luévano‐Martínez, Luis Alberto, Chausse, Bruno, Kowaltowski, Alicia J. · 2017 · Aging Cell
70. Neurons Efficiently Repair Glutamate-induced Oxidative DNA Damage by a Process Involving CREB-mediated Up-regulation of Apurinic Endonuclease 1
    Jenq‐Lin Yang, Takashi Tadokoro, Guido Keijzers, Mark P. Mattson, Vilhelm A. Bohr · 2010 · Journal of Biological Chemistry
71. Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice
    Yves Porte, Marie-Christine Buhot, Nicole E. Mons · 2007 · Neurobiology of Aging
72. Mitochondrial Complex 1 Activity Measured by Spectrophotometry Is Reduced across All Brain Regions in Ageing and More Specifically in Neurodegeneration
    Pollard, Amelia Kate, Craig, Emma Louise, Chakrabarti, Lisa · 2016 · PLOS ONE
73. Rapamycin up-regulation of autophagy reduces infarct size and improves outcomes in both permanent MCAL, and embolic MCAO, murine models of stroke
    Kathleen M Buckley, Daniel L. Hess, Irina Y. Sazonova, Sudharsan Periyasamy‐Thandavan, John R Barrett, Russell C. Kirks, Harrison E. Grace, Galina Kondrikova, Maribeth H. Johnson, David Charles Hess et al. · 2014 · Experimental & Translational Stroke Medicine
74. Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development
    Yan Hou, Xin Ouyang, Ruiqian Wan, Heping Cheng, Mark P. Mattson, Aiwu Cheng · 2012 · Stem Cells
75. Roles for NF-κB and Gene Targets of NF-κB in Synaptic Plasticity, Memory, and Navigation
    Wanda M. Snow, Brenda M. Stoesz, Debbie M. Kelly, Benedict C. Albensi · 2013 · Molecular Neurobiology
76. Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair
    Eric P. Knott, Mazen Assi, Sudheendra N.R. Rao, Mousumi Ghosh, Damien Daniel Pearse · 2017 · International Journal of Molecular Sciences
77. Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions
    Ishita J. Parikh, Janet Guo, Kai‐Hsiang Chuang, Yu Zhong, Ralf G. Rempe, Jared D. Hoffman, Rachel Armstrong, Björn Bauer, Anika M. S. Hartz, Ai‐Ling Lin · 2016 · Aging
78. Abdominal obesity and lower gray matter volume: a Mendelian randomization study
    Stéphanie Debette, Christiane Wolf, Jean‐Charles Lambert, Fabrice Crivello, Aïcha Soumaré, Yi‐Cheng Zhu, Sabrina Schilling, Carole Dufouil, Bernard M. Mazoyer, Philippe Amouyel et al. · 2013 · Neurobiology of Aging
79. Brain Region-Specific, Age-Related, Alterations in Mitochondrial Responses to Elevated Calcium
    Maile R. Brown, James W. Geddes, Patrick G. Sullivan · 2004 · Journal of Bioenergetics and Biomembranes
80. Functional Role of Soluble Receptor for Advanced Glycation End Products in Stroke
    Sung‐Chun Tang, Yu-Chi Wang, Yu‐I Li, Hsiao-Ching Lin, Silvia Manzanero, Yu-Hsuan Hsieh, Simon Phipps, Chaur‐Jong Hu, Hung‐Yi Chiou, Yi‐Shuian Huang et al. · 2013 · Arteriosclerosis Thrombosis and Vascular Biology
81. Functional connectivity with the retrosplenial cortex predicts cognitive aging in rats
    Jessica A. Ash, Hanbing Lu, Lisa R. Taxier, Jeffrey M. Long, Yihong Yang, Elliot A. Stein, Peter R. Rapp · 2016 · Proceedings of the National Academy of Sciences
82. Diet-induced obesity and low testosterone increase neuroinflammation and impair neural function
    Anusha Jayaraman, Daniella Lent-Schochet, Christian J. Pike · 2014 · Journal of Neuroinflammation
83. Glucocorticoid receptor activation impairs hippocampal plasticity by suppressing BDNF expression in obese mice
    Marlena Wosiski‐Kuhn, Joanna Erion, Elise P. Gómez-Sánchez, Celso E. Gómez-Sánchez, Alexis M. Stranahan · 2014 · Psychoneuroendocrinology
84. Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology
    Dick Jaarsma, Ingrid van der Pluijm, Monique C. de Waard, Elize D. Haasdijk, Renata M. C. Brandt, Marcel Vermeij, Yvonne Rijksen, Alex Maas, Harry VAN STEEG, Jan H.J. Hoeijmakers et al. · 2011 · PLoS Genetics
85. Age-related decrease in brain synaptic membrane Ca2+-ATPase in F344/BNF1 rats
    Asma Zaidi, Jun Gao, Thomas C. Squier · 1998 · Neurobiology of Aging
86. Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging
    Silvia Lores‐Arnaiz, Paulina Lombardi, Analía G. Karadayian, Federico Orgambide, Daniela Cicerchia, Juanita Bustamante · 2016 · Neurochemical Research
87. Telomere Protection Mechanisms Change during Neurogenesis and Neuronal Maturation: Newly Generated Neurons Are Hypersensitive to Telomere and DNA Damage
    Aiwu Cheng, Kazuo Shin‐ya, Ruiqian Wan, Sung‐Chun Tang, Takumi Miura, Hongyang Tang, Rina G. Khatri, Marc Gleichman, Xin Ouyang, Dong Liu et al. · 2007 · Journal of Neuroscience
88. Impact of Aging on Endurance and Neuromuscular Physical Performance: The Role of Vascular Senescence
    Gonçalo V. Mendonça, Pedro Pezarat‐Correia, João Rocha Vaz, Luís Silva, Kevin S. Heffernan · 2016 · Sports Medicine
89. Neural activity and CaMKII protect mitochondria from fragmentation in aging Caenorhabditis elegans neurons
    Hao-Ching Jiang, Jiun-Min Hsu, Chien-Ping Yen, Chi‐Chao Chao, Ruey‐Hwa Chen, Chun‐Liang Pan · 2015 · Proceedings of the National Academy of Sciences
90. Aging and Caloric Restriction Affect Mitochondrial Respiration and Lipid Membrane Status: An Electron Paramagnetic Resonance Investigation
    S. Prasad Gabbita, David Allan Butterfield, Kenneth Hensley, Wendy Shaw, John M. Carney · 1997 · Free Radical Biology and Medicine
91. Reduced GABAAReceptor-Mediated Tonic Inhibition in Aged Rat Auditory Thalamus
    Ben D. Richardson, Lynne L. Ling, Victor V. Uteshev, Donald M. Caspary · 2013 · Journal of Neuroscience
92. Late-Life Environmental Enrichment Induces Acetylation Events and Nuclear Factor κB-Dependent Regulations in the Hippocampus of Aged Rats Showing Improved Plasticity and Learning
    Romain Neidl, Anne Schneider‐Anthony, Olivier Bousiges, Mark J. Majchrzak, Alexandra Barbelivien, Anne Pereira de Vasconcelos, Kevin Dorgans, Frédéric Doussau, Jean‐Philippe Loeffler, Jean‐Christophe Cassel et al. · 2016 · Journal of Neuroscience
93. Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons
    Jacqueline A. Bayliss, Moyra B. Lemus, Vanessa Valgas dos Santos, Minh Deo, Jeffrey S. Davies, Bruce E. Kemp, John D. Elsworth, Zane Bruce Andrews · 2016 · PLoS ONE
94. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits
    Hongjie Wang, Ruizhi Wang, Iván Carrera, Shaohua Xu, Madepalli Krishnappa Lakshmana · 2016 · eNeuro
95. Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal
    Shi Zhang, Erez Eitan, Tsung-Yu Wu, Mark P. Mattson · 2017 · Neurobiology of Aging
96. Ca2+ signaling, mitochondria and sensitivity to oxidative stress in aging astrocytes
    Da‐Ting Lin, Jun Wu, Deborah M. Holstein, Geeta Upadhyay, Wendy Rourk, Elizabeth Muller, James Donald Lechleiter · 2005 · Neurobiology of Aging
97. Aging Neural Progenitor Cells Have Decreased Mitochondrial Content and Lower Oxidative Metabolism
    Elizabeth Ann Stoll, Willy Cheung, Andrei M. Mikheev, Ian R. Sweet, Jason H. Bielas, Jing Zhang, Robert Rostomily, Philip J. Horner · 2011 · Journal of Biological Chemistry
98. Higher body mass index is associated with reduced posterior default mode connectivity in older adults
    Frauke Beyer, Sharzhad Kharabian Masouleh, Julia M. Huntenburg, Leonie Lampe, Tobias Luck, Steffi Gerlinde Riedel-Heller, Markus Loeffler, Matthias Leopold Schroeter, Michael Stümvoll, Arno Villringer et al. · 2017 · Human Brain Mapping
99. The impact of base excision DNA repair in age-related neurodegenerative diseases
    Leandro, Giovana S., Sykora, Peter, Bohr, Vilhelm A. · 2015 · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
100. Adapting the concepts of brain and cognitive reserve to post-stroke cognitive deficits: Implications for understanding neglect
     Roza M. Umarova · 2016 · Cortex
101. Elevated Body Mass Index is Associated with Increased Integration and Reduced Cohesion of Sensory-Driven and Internally Guided Resting-State Functional Brain Networks
     Gaelle Eve Doucet, Natalie Rasgon, Bruce S. McEwen, Nadia Micali, Sophia Frangou · 2017 · Cerebral Cortex
102. Decreased mitochondrial bioenergetics and calcium buffering capacity in the basal ganglia correlates with motor deficits in a nonhuman primate model of aging
     Pandya, Jignesh D., Grondin, Richard, Yonutas, Heather M., Haghnazar, Hamed, Gash, Don M., Zhang, Zhiming, Sullivan, Patrick G. · 2015 · Neurobiology of Aging
103. Body–Brain Connections: The Effects of Obesity and Behavioral Interventions on Neurocognitive Aging
     Chelsea M. Stillman, Andrea M. Weinstein, Anna L. Marsland, Peter J. Gianaros, Kirk I. Erickson · 2017 · Frontiers in Aging Neuroscience
104. Mitochondrial DNA and Parkinson's disease
     Donato A. Di Monte · 1991 · Neurology
105. The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up‐regulation
     Liu, Dong, Zhang, Yongqing, Gharavi, Robert, Park, Hee Ra, Lee, Jaewon, Siddiqui, Sana, Telljohann, Richard, Nassar, Matthew R., Cutler, Roy G., Becker, Kevin G. et al. · 2015 · Journal of Neurochemistry
106. Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein
     Kathleen J. S. Griffioen, Sarah M. Rothman, Bruce Ladenheim, Ruiqian Wan, Neil M. Vranis, Emmette R. Hutchison, Eitan Okun, Jean Lud Cadet, Mark P. Mattson · 2012 · Neurobiology of Aging
107. Age-related loss of calcium binding proteins in rabbit hippocampus
     G.I. de Jong, Pieterke A. Naber, Eddy A. van der Zee, Lucien T. Thompson, John F. Disterhoft, Paul G.M. Luiten · 1996 · Neurobiology of Aging
108. Trophic factors for Parkinson's disease: To live or let die
     C. Warren Olanow, Raymond T. Bartus, Laura A. Volpicelli‐Daley, Jeffrey H. Kordower · 2015 · Movement Disorders
109. Chaperone mediated autophagy in aging: Starve to prosper
     Maria Xilouri, Leonidas Stefanis · 2016 · Ageing Research Reviews
110. Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus
     John C. Gant, Kuey-Chu Chen, Inga Kadish, Eric M. Blalock, Olivier Thibault, Nada M. Porter, Philip W. Landfield · 2015 · Journal of Neuroscience
111. Redox proteomics and the dynamic molecular landscape of the aging brain
     Marzia Perluigi A, Aaron M. Swomley, David Allan Butterfield · 2013 · Ageing Research Reviews
112. A 3-Month Aerobic Training Program Improves Brain Energy Metabolism in Mild Alzheimer’s Disease: Preliminary Results from a Neuroimaging Study
     Christian‐Alexandre Castellano, Nancy Paquet, Isabelle J. Dionne, Hélène Imbeault, Francis Langlois, Étienne Croteau, Sébastien Tremblay, Mélanie Fortier, J. J. Matte, Guy Lacombe et al. · 2017 · Journal of Alzheimer s Disease
113. Serotinin, Aging and Cognitive Functions of the Hippocampus
     Gal Richter‐Levin, Menahem Segal · 1996 · Reviews in the Neurosciences
114. Inhibitory dysfunction contributes to some of the motor and non-motor symptoms of movement disorders and psychiatric disorders
     Marjan Jahanshahi, John C. Rothwell · 2017 · Philosophical Transactions of the Royal Society B Biological Sciences
115. Ultrastructural evidence for impaired mitochondrial fission in the aged rhesus monkey dorsolateral prefrontal cortex
     Yury M. Morozov, Dibyadeep Datta, Constantinos D. Paspalas, Amy F.T. Arnsten · 2016 · Neurobiology of Aging
116. Oxidative Stress and Neuronal DNA Fragmentation Mediate Age-Dependent Vulnerability to the Mitochondrial Toxin, 3-Nitropropionic Acid, in the Mouse Striatum
     Gyung Whan Kim, Pak Hoo Chan · 2001 · Neurobiology of Disease
117. Impaired Adaptive Cellular Responses to Oxidative Stress and the Pathogenesis of Alzheimer's Disease
     Sarah J. Texel, Mark P. Mattson · 2010 · Antioxidants and Redox Signaling
118. Evolutionary and functional perspectives on signaling from neuronal surface to nucleus
     Samuel M. Cohen, Boxing Li, Richard W. Tsien, Huan Ma · 2015 · Biochemical and Biophysical Research Communications
119. Individual differences in neurocognitive aging of the medial temporal lobe
     Michela Gallagher, Carlo Colantuoni, Howard Eichenbaum, Rebecca P. Haberman, Peter R. Rapp, Heikki Tanila, Iain A. Wilson · 2006 · AGE
120. An atypical role for the myeloid receptor Mincle in central nervous system injury
     Thiruma Valavan Arumugam, Silvia Manzanero, Milena Bastos Furtado, Patrick J. Biggins, Yu-Hsuan Hsieh, Mathias Gelderblom, Kelli P. A. MacDonald, Ekaterina Salimova, Yu‐I Li, Othmar Korn et al. · 2016 · Journal of Cerebral Blood Flow & Metabolism
121. Age-related changes in neural volume and microstructure associated with interleukin-6 are ameliorated by a calorie-restricted diet in old rhesus monkeys
     Willette, A.A., Bendlin, B.B., McLaren, D.G., Canu, E., Kastman, E.K., Kosmatka, K.J., Xu, G., Field, A.S., Alexander, A.L., Colman, R.J. et al. · 2010 · NeuroImage
122. Role of the AMPK pathway in promoting autophagic flux via modulating mitochondrial dynamics in neurodegenerative diseases: Insight into prion diseases
     Shah, Syed Zahid Ali, Zhao, Deming, Hussain, Tariq, Yang, Lifeng · 2017 · Ageing Research Reviews
123. Dendritic mRNA Targeting and Translation
     Stefan Kindler, Hans‐Jürgen Kreienkamp · 2012 · Advances in experimental medicine and biology
124. Caloric Restriction Impedes Age-Related Decline of Mitochondrial Function and Neuronal Activity
     Ai‐Ling Lin, Daniel Coman, Lihong Jiang, Douglas L. Rothman, Fahmeed Hyder · 2014 · Journal of Cerebral Blood Flow & Metabolism
125. Impaired glucose tolerance in midlife and longitudinal changes in brain function during aging
     Thambisetty, Madhav, Beason-Held, Lori L., An, Yang, Kraut, Michael, Metter, Jeffrey, Egan, Josephine, Ferrucci, Luigi, O'Brien, Richard, Resnick, Susan M. · 2013 · Neurobiology of Aging
126. Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism
     Eitan Okun, Kathleen J. S. Griffioen, Sarah M. Rothman, Ruiqian Wan, Wei-Na Cong, Rafael de Cabo, Alejandro Martín‐Montalvo, Andrew Levette, Stuart R. Maudsley, Bronwen Martin et al. · 2013 · Brain Behavior and Immunity
127. Cellular functions of LRRK2 implicate vesicular trafficking pathways in Parkinson's disease
     Mark Cookson · 2016 · Biochemical Society Transactions
128. Age- and brain region-specific differences in mitochondrial bioenergetics in Brown Norway rats
     Pandya, Jignesh D., Royland, Joyce E., MacPhail, Robert C., Sullivan, Patrick G., Kodavanti, Prasada Rao S. · 2016 · Neurobiology of Aging
129. Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice
     Montasir Elahi, Zafrul Hasan, Yumiko Motoi, Shin‐ei Matsumoto, Koichi Ishiguro, Nobutaka Hattori · 2016 · Journal of Alzheimer s Disease
130. Hippocampal calcium dysregulation at the nexus of diabetes and brain aging
     Olivier Thibault, Katie L. Anderson, Chris DeMoll, Lawrence D. Brewer, Philip W. Landfield, Nada M. Porter · 2013 · European Journal of Pharmacology
131. CSF phosporylated TAU protein levels correlate with cerebral glucose metabolism assessed with PET in Alzheimer's disease
     Roberto Ceravolo, Davide Borghetti, Lorenzo Kiferle, Gloria Tognoni, Assuero Giorgetti, Danilo Neglia, N. Sassi, Daniela Frosini, Carlo Alfonso Rossi, Lucia Petrozzi et al. · 2008 · Brain Research Bulletin
132. Systematic administration of iptakalim, an ATP‐sensitive potassium channel opener, prevents rotenone‐induced motor and neurochemical alterations in rats
     Yong Yang, Xing Liu, Yan Long, Fang Wang, Jianhua Ding, Suyi Liu, Ye‐Hong Sun, Honghong Yao, Hai Wang, Jie Wu et al. · 2005 · Journal of Neuroscience Research
133. Quantification of in vivo oxidative damage in Caenorhabditis elegans during aging by endogenous F3‐isoprostane measurement
     Christiaan F. Labuschagne, Edwin C.A. Stigter, Margriet M. W. B. Hendriks, Ruud Berger, Joshua Rokach, Hendrik C. Korswagen, Arjan B. Brenkman · 2012 · Aging Cell
134. Early involvement of lysosome dysfunction in the degeneration of cerebral cortical neurons caused by the lipid peroxidation product 4‐hydroxynonenal
     Shi Zhang, Erez Eitan, Mark P. Mattson · 2017 · Journal of Neurochemistry
135. Age and the metabolic syndrome as risk factors for ischemic stroke: improving preclinical models of ischemic stroke.
     Brandon Peter Lucke-Wold, Ryan Coddington Turner, Noelle Lucke-Wold, Charles Lee Rosen, Jason Delwyn Huber · 2012 · Europe PMC (PubMed Central)
136. Bioenergetics and metabolism: a bench to bedside perspective
     Russell Howard Swerdlow · 2016 · Journal of Neurochemistry
137. Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle
     Mark P. Mattson · 2015 · npj Aging and Mechanisms of Disease
138. Glucose-dependent insulinotropic polypeptide: effects on insulin and glucagon secretion in humans.
     Mikkel Christensen · 2016 · PubMed
139. Neuroprotective effects of 2,4-dinitrophenol in an acute model of Parkinson’s disease
     Yujeong Lee, Gwangbeom Heo, Kyung Moon Lee, Ah Hyun Kim, Ki Wung Chung, Eunok Im, Hae Young Chung, Jaewon Lee · 2017 · Brain Research
140. Hippocampal slices from long-term streptozotocin-injected rats are prone to epileptiform responses
     Doru Georg Margineanu, Isabelle Niespodziany, Ernst Wülfert · 1998 · Neuroscience Letters
141. Aging-associated neuropathology in Werner syndrome
     James B. Leverenz, Chang‐en Yu, Gerard D. Schellenberg · 1998 · Acta Neuropathologica
142. Cockayne Syndrome Group B (Csb) and Group A (Csa) Deficiencies Predispose to Hearing Loss and Cochlear Hair Cell Degeneration in Mice
     Nagtegaal, A. Paul, Rainey, Robert N., van der Pluijm, Ingrid, Brandt, Renata M.C., van der Horst, Gijsbertus T.J., Borst, J. Gerard G., Segil, Neil · 2015 · The Journal of Neuroscience
143. Combination Therapy with Low-Dose IVIG and a C1-esterase Inhibitor Ameliorates Brain Damage and Functional Deficits in Experimental Ischemic Stroke
     Xinzhi Chen, Thiruma Valavan Arumugam, Yi‐Lin Cheng · 2018 · NeuroMolecular Medicine
144. Clinical Advances in Geriatric Psychiatry
     Harris A. Eyre, Bernhard Theodor Baune, Helen Lavretsky · 2015 · Psychiatric Clinics of North America
145. Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus
     Kirsten Thomsen, Takashi Yokota, Md Mahdi Hasan‐Olive, Niloofar Sherazi Dreyer, Nima Borhan Fakouri, Claus Desler, Christine Elisabeth Regnell, Steen Larsen, Lene Juel Rasmussen, Flemming Dela et al. · 2017 · Neurobiology of Aging
146. Neurodegeneration in accelerated aging.
     Moren Scheibye-Knudsen · 2016 · PubMed
147. Modulation of Effective Connectivity in the Default Mode Network at Rest and During a Memory Task
     Xingfeng Li, Elizabeth G. Kehoe, T.M. McGinnity, Damien Coyle, Arun L.W. Bokde · 2014 · Brain Connectivity
148. Cognitive differences between Sprague-Dawley rats selectively bred for sensitivity or resistance to diet induced obesity
     Sunam Gurung, Martin‐Paul Agbaga, Dean A. Myers · 2016 · Behavioural Brain Research
149. Cognitive deficit in hippocampal-dependent tasks in Werner syndrome mouse model
     Khaoula Rekik, Bernard Francès, Philippe Valet, Cédric Dray, Cédrick Florian · 2017 · Behavioural Brain Research
150. Increased activity of surviving locus ceruleus neurons in Alzheimer's disease
     Moser · 1999 · Pure Amsterdam UMC
151. Untitled work
     1999 · 10.1002/(sici)1097-4547(19990915)57:6
152. Untitled work
     1999 · 10.1002/(sici)1097-4547(19990715)57:2