Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590

Microenvironmental regulation of tumor progression and metastasis

Quail, D. F., & Joyce, J. A. (2013) · Nature Medicine · doi:10.1038/nm.3394 · Cited by 7,994

Role of YAP/TAZ in mechanotransduction

Dupont, S., Morsut, L., Aragona, M., Enzo, E., Giulitti, S., Cordenonsi, M., Zanconato, F., Le Digabel, J., Forcato, M., Bicciato, S., et al. (2011) · Nature · doi:10.1038/nature10137 · Cited by 5,979

The biology and function of fibroblasts in cancer

Kalluri, R. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2016.73 · Cited by 4,366

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., et al. (2009) · Cell · doi:10.1016/j.cell.2009.10.027 · Cited by 4,101

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., & Thompson, C. B. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2007.10.002 · Cited by 4,088

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

Yang, J., Mani, S. A., Donaher, J. L., Ramaswamy, S., Itzykson, R., Côme, C., Savagner, P., Gitelman, I., Richardson, A. L., & Weinberg, R. A. (2004) · Cell · doi:10.1016/j.cell.2004.06.006 · Cited by 3,917

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Sancak, Y., Peterson, T. R., Shaul, Y. D., Lindquist, R. A., Thoreen, C. C., Bar-Peled, L., & Sabatini, D. M. (2008) · Science · doi:10.1126/science.1157535 · Cited by 2,773

Understanding the Intersections between Metabolism and Cancer Biology

Heiden, M. G. V., & DeBerardinis, R. J. (2017) · Cell · doi:10.1016/j.cell.2016.12.039 · Cited by 2,369

Hippo pathway in organ size control, tissue homeostasis, and cancer

Yu, F.-X., Zhao, B., & Guan, K.-L. (2015) · Cell · doi:10.1016/j.cell.2015.10.044 · Cited by 2,206

Research progress on the role of biomechanical clues in the progression of lung cancer

Gong, F., Zhang, Q., Qin, F., Qu, R., Wang, C., Yang, T., Fan, T., Lv, Y., & Dai, J. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1581831 · Cited by 3

Evaluation of LC/MS Methods for Hydrophilic Metabolites to Enable Integration of Human Blood Metabolome Data

Imado, Y., Takahashi, M., Soma, Y., Aburaya, S., Nakatani, K., Hanai, T., Bamba, T., & Izumi, Y. (2026) · Mass Spectrometry · doi:10.5702/massspectrometry.a0188 · Cited by 3

Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies

Xie, W., Fang, J., Wang, Z., Li, X., Du, J., & Ling, C. (2026) · Cancer Gene Therapy · doi:10.1038/s41417-026-01007-w · Cited by 3

Hydrostatic pressure regulates glutamine metabolism to promote bladder fibroblast activation via the Piezo1/YAP1/GLS1 axis

Li, K., Wei, P., Li, Z., Kuang, W., Zhang, M., Luo, C., Cui, K., Lin, D., & Chen, Z. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07855-2 · Cited by 5

Cellular mechanometabolism: stimuli and implications

Ortiz, I., Lopez, S., Kondapaneni, R. V., Hernández, J. A., Boone, K., & Reinhart‐King, C. A. (2026) · EMBO Reports · doi:10.1038/s44319-026-00795-4 · Cited by 3

[A cervical cancer tissue-derived decellularized extracellular matrix scaffold for cervical cancer tissue reconstruction in vitro].

Mao, J., Wenjing, Y., Guo, H., Dong, R., Ren, L., & Li, S. (2023) · PubMed Central · doi:10.12122/j.issn.1673-4254.2023.02.01 · Cited by 3

Untangling the web of glioblastoma treatment resistance using a multi-omic and multidisciplinary approach

Miller, D. M., Yadanapudi, K., Rai, V., Rai, S. N., Chen, J., Frieboes, H. B., Masters, A. H., McCallum, A. P., & Williams, B. J. (2023) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2023.06.010 · Cited by 3

The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications

Gerardo, H., Oliveira, P. J., Cavadas, C., Grãos, M., & Teixeira, J. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167678 · Cited by 4

Mechanically Tunable Hydrogel Microfibers for Biomimetic Tumor Drug Testing

Song, T., Shen, Q., Cheng, Y., Zhi, Y., Liu, G., Ren, H., & Wang, J. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202502840 · Cited by 3

Surface Avidity of Anionic Polypeptide Coatings on Layer‐by‐Layer Nanoparticles Target Cancer‐Associated Amino Acid Transporters

Pires, I. S., Billingsley, M. M., Gordon, E., Pickering, A. J., Cai, E., Esparza, G. J., Pryor, M. L., Stoneman, A. D., Kindopp, A., Irvine, D. J., et al. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202519203 · Cited by 4

Probiotic Lactobacillus brevis CLB3 prevents azoxymethane/dextran sulfate sodium-induced colon carcinogenesis in mice by reducing amino acid transport and IL-17A levels and repressing the IL-6/AKT/p-STAT3 signaling pathway

Qian, W., Zhang, Y., Long, Y., Yang, W., Hu, R., Li, J., Leng, Y., Liu, X., Li, Q. X., Wan, X., et al. (2022) · Food Quality and Safety · doi:10.1093/fqsafe/fyac038 · Cited by 3

Dysregulated microRNAs and long non-coding RNAs associated with extracellular matrix stiffness

Qiu, H., Fu, Y., Guo, Z., Zhang, X., Wang, X., & Wu, H. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.114014 · Cited by 3

Mechanical network motifs as targets for mechanomedicine

Lu, M., Zhao, X., Xu, F., Yin, C., Guo, H., & Cheng, B. (2024) · Drug Discovery Today · doi:10.1016/j.drudis.2024.104145 · Cited by 3

Metabolic Pathways of Eukaryotes and Connection to Cell Mechanics

Mierke, C. T. (2020) · Biological and medical physics, biomedical engineering · doi:10.1007/978-3-030-58532-7_17 · Cited by 2

Constructing Voronoi Diagram of a Point Set on Mesh of Trees.

Lee, F., & Zheng, S.-Q. (1992) · Proceedings of the International Conference on Parallel Processing · Cited by 3

The combined inhibition of SLC1A3 and glutaminase in osimertinib-resistant EGFR mutant cells

Ochi, N., Miyake, N., Takeyama, M., Yamane, H., Fukazawa, T., Nagasaki, Y., Kawahara, T., Ichiyama, N., Kosaka, Y., Mimura, A., et al. (2024) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2024.130675 · Cited by 2

Overview of glutamine metabolism in stromal components of the tumor microenvironment and potential anti-tumor therapies

Li, Z., Deng, J., Wang, H., Liu, T., Zhou, Y., Ouyang, P., Liang, X., Zhang, X., Qi, S., & Li, Y. (2025) · Genes & Diseases · doi:10.1016/j.gendis.2025.101834 · Cited by 3

Myosin-actin pattern links matrix stiffness to GFAT2-hyaluronan metabolism

Zhou, Y., Zheng, Y., Sheng, B., Wang, J., Ding, K., Ji, B., & Wu, Y. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102305 · Cited by 2

The paradox of nuclear miRNAs: Mechanisms, therapeutic potential, and future directions

Yang, K., Zhang, C., Zhao, Z., Feng, M., Song, L., & Xu, Z. (2026) · Non-coding RNA Research · doi:10.1016/j.ncrna.2026.01.010 · Cited by 2

Research progress on tumor extracellular matrix stiffness and immunosuppression

Wu, F., Zhang, P., Wu, W., Tian, H., Jiang, X., & Huang, T. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1852616 · Cited by 2

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

He, X., Zhao, G., Hu, Y., Bai, W., Tan, H., Yuan, S., Yang, S., Zhu, Y., Xu, X., & Zheng, L. (2026) · Advanced Science · doi:10.1002/advs.76518 · Cited by 2

Bioinformatics analysis and experimental validation of the oncogenic role of COL11A1 in pan-cancer

Wan, X., Deng, Q., Chen, A., Zhang, X., & Yang, W. (2024) · 3 Biotech · doi:10.1007/s13205-024-04133-0 · Cited by 2

In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging

Duré, C., Ghoshdastider, U., Weber, R., Khandekar, A., Valdivia-Francia, F., Renz, P. F., Sella, F., Hyams, K., Taborsky, D., Yiğit, M., et al. (2026) · Molecular Cell · doi:10.1016/j.molcel.2026.04.017 · Cited by 3

Mechanical mechanics-reclaiming a new battlefield for chronic liver disease

Zhang, Y., Ma, T., Lu, X., Hua, H., Wu, L., & Chen, Z. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.05.028 · Cited by 3

Targeting cancer-associated fibroblasts in immunotherapy

Kim, D., Wu, Y., & Oh, Y. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85781-9.00007-5 · Cited by 2

Current Model Systems for Investigating Epithelioid Haemangioendothelioma

Neil, E., & Kouskoff, V. (2023) · Cancers · doi:10.3390/cancers15113005 · Cited by 2

Effect of preserved eggs on the health of SD rats, and anti‐tumor action of HT‐29 cells

Wu, Y., Mao, C., Hu, G., Ma, L., Li, S., & Ma, M. (2023) · Food Science & Nutrition · doi:10.1002/fsn3.3558 · Cited by 2

Targeting tumor intrinsic metabolic node in pancreatic cancer causes tumor regression,remodels extracellular matrix and sensitizes to anti-PD1 therapy

Sharma, N., Gupta, V. K., Garrido, V. T., Hadad, R., Durden, B. C., Kesh, K., Ferrantella, A. R., Giri, B., Dudeja, V., Banerjee, S., et al. (2019) · Pancreatology · doi:10.1016/j.pan.2019.05.430 · Cited by 2

Biophysical forces rewire cell metabolism to guide microtubule-dependent cell mechanicsPreprint

Torrino, S., Audebert, S., Belhadj, I., Lacoux, C., Pisano, S., Abélanet, S., Brau, F., Chan, S. Y., Mari, B. P., Oldham, W. M., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.10.985036 · Cited by 2

Reconstructing cell interactions and state trajectories in pancreatic cancer stromal tumoroidsPreprint

Okuda, R., Gjeta, B., Popovic, D., Maynard, A., Yu, Q., He, Z., Santel, M., Seimiya, M., Morinaga, S., Miyagi, Y., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.14.480334 · Cited by 2

Metabolic Atlas of Human Eyelid Infiltrative Basal Cell Carcinoma

Huang, Y., He, C., Hu, Q., Liu, Z., Li, X., Gao, W., Liang, X., Chen, R., Mao, Z., & Lin, X. (2025) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.66.1.11 · Cited by 1

VPS45 promotes the progression of hepatocellular carcinoma by recycling β1 integrin to the cell membrane via the endocytic pathway

Ofuchi, T., Otsu, H., Hosoda, K., Ikehara, T., Tsujimoto, A., Higuchi, S., Shibuta, S., Ono, Y., Hirose, K., Tsuda, Y., et al. (2025) · Journal of Gastroenterology · doi:10.1007/s00535-025-02278-0 · Cited by 1

Fuel, form, and memory: The motility-driven journey of cancer cells

Trenado-Yuste, C., & Nelson, C. M. (2025) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2025.100624 · Cited by 1

Identification and validation of a refined CAF-Associated diagnostic signature in breast cancer

Zhou, X., Wang, N., Shi, L., Wei, D., Sun, X., Shao, M., Tian, L., Guo, X., Zhang, F., & Lyu, H. (2026) · Scientific Reports · doi:10.1038/s41598-025-34923-2 · Cited by 1

Cancer-Associated Fibroblasts in the Treatment of Intrahepatic Cholangiocarcinoma: Present and Prospects

Yuan, Y., Zhang, R., Qu, C., Huang, N., Wang, L., & Liu, M. (2026) · Journal of Hepatocellular Carcinoma · doi:10.2147/jhc.s581943 · Cited by 1

Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast peritumor microenvironment

Najera, J., Chen, H., Batista, B., Ketchum, F., Ali, A., Zorlutuna, P., Howard, S. S., & Datta, M. (2026) · iScience · doi:10.1016/j.isci.2026.115931 · Cited by 1

Bioengineered systems to exploit tumor microenvironment metabolism

Sanganoo, C., Caturegli, I., Mattes, Z. F., Ryan, J., Wong, W. W., & Grinstaff, M. W. (2026) · Trends in cancer · doi:10.1016/j.trecan.2026.04.003 · Cited by 1

The role of cancer-associated fibroblasts in various cancer drug resistance

Dang, F., Na, J., Xiao, L., Tian, X., Shao, J., Zhong, L., & Zhao, Y. (2026) · Cancer Letters · doi:10.1016/j.canlet.2026.218584 · Cited by 1

Metabolic reprogramming of cancer associated fibroblasts informs stromal heterogeneity and therapeutic targeting

Ma, H., Lu, H., Zhang, Z., Wang, J., Zhao, Q., Ding, Y., Wang, X., Zhang, W., Li, N., & Wang, S. (2026) · Discover Oncology · doi:10.1007/s12672-026-05562-4 · Cited by 1

Extracellular matrix stiffness and mechanotransduction in cancer drug resistance

Song, Y., Huang, C., Han, J., Wang, S., Liu, H., Li, Y., Jiang, Z., Tan, X., Wu, T., & Jiang, F. (2026) · Drug Resistance Updates · doi:10.1016/j.drup.2026.101470 · Cited by 1

Cancer Metabolism and Aggressive Tumor Behavior

Chaudhary, S., Shah, A., Pothuraju, R., Lakshmanan, I., Ganti, A. K., & Batra, S. K. (2022) · Springer eBooks · doi:10.1007/978-981-16-6226-3_2 · Cited by 1

Autophagy in cancer-associated fibroblasts: biology and targeting

Ly, T., Gaur, G., & Thomas, S. M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-99879-6.00004-3 · Cited by 1

[Advances in Research on Cell Metabolic Interactions in the Tumor Microenvironment].

Wu, P., Yang, Z., Li, Q., & Wang, D. (2024) · PubMed Central · doi:10.12182/20240360606 · Cited by 1

A novel cancer-associated fibroblasts risk score model predict survival and immunotherapy in lung adenocarcinoma

Kong, F., Lu, Z., Xiong, Y., Zhou, L., & Ye, Q. (2024) · Molecular Genetics and Genomics · doi:10.1007/s00438-024-02156-z · Cited by 1

Secretome analysis of cancer-associated fibroblasts from prostate cancer to identify potential therapeutic targetsPreprint

Abikar, A., Mohammad, M. M. S., Athalye, R. R., Nadig, N., Tamboli, N., Babu, V., Keshavamurthy, R., & Ranganathan, P. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.09.627457 · Cited by 1

Tumor starvation by deprivation of glutamine and aspartate

Fried, R., Carlton, R. M., & Fried, D. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-824013-7.00008-0

Faculty Opinions recommendation of A framework for advancing our understanding of cancer-associated fibroblasts.

Timpson, P. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.737260944.793580089

Role of cancer-associated fibroblasts in colorectal cancer

Liang, Q., & Zhou, X.-H. (2023) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v31.i4.129

Role of cancer-associated fibroblasts in colorectal cancer

Liang, Q., & Zhou, X.-H. (2023) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v31.i4.134

A new prognostic signature based on cancer associated fibroblast-driven genes in breast cancerPreprint

Wu, Z., Wei, Y., Liu, Y., Zheng, J., Yan, W., Liu, J., Han, M., & Li, T. (2023) · Research Square · doi:10.21203/rs.3.rs-2740940/v1

Amino Acids and Their Derivatives in Oncology: A Review

Нефёдов, Л. И. (2023) · Лабораторная диагностика Восточная Европа · doi:10.34883/pi.2023.12.1.008

The identification of cancer-associated fibroblasts signature for prognosis and drug response in renal papillary cell carcinoma

Liu, X., Yang, L., & Dong, Q. G. (2023) · Asian Journal of Surgery · doi:10.1016/j.asjsur.2023.05.073

COL5A2-Dependent Cancer-associated Fibroblasts (CAF) Reveals Regulation of the Tumor Microenvironment and Response to Immunotherapy in Lung Adenocarcinoma

Shi, X., Wang, X., Chang, X., Li, K., & Cai, Y. (2023) · Journal of Oncology Research and Therapy · doi:10.29011/2574-710x.10186

Biomechanical imaging biomarker during chemoradiotherapy predicts treatment response in head and neck squamous cell carcinoma

Fujimoto, K., Shiinoki, T., Kawazoe, Y., Yuasa, Y., Mukaidani, W., Manabe, Y., Kajima, M., & Tanaka, H. (2024) · Physics in Medicine and Biology · doi:10.1088/1361-6560/ad29b9

Extracellular Matrix Remodeling in Physiological and Pathological Conditions: Insight into Extracellular Vesicles Contribution

Poppa, G., Giusti, I., & Dolo, V. (2024) · Biology of extracellular matrix · doi:10.1007/978-3-031-68811-9_2

Instant fluorescence lifetime imaging microscopy reveals mechano-metabolic reprogramming of stromal cells in breast cancer peritumoral microenvironmentsPreprint

Najera, J., Chen, H., Batista, B., Ketchum, F., Ali, A., Zorlutuna, P., Howard, S. S., & Datta, M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.28.656717

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

Liao, M., Rao, Y., Li, M., Guo, J., Guo, K., Li, K., Zheng, R., Liu, Y., Wang, Q., Wang, M., et al. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2025.1658299

The differential effect of glutamine supplementation on the orthotopic and subcutaneous growth of two syngeneic murine models of glioma

Maurer, J., Mukherjee, P., Ta, N. L., Lee, D. C., Duraj, T., Henao, J., Kiebish, M., Cura, D. V., Herdocia, M., & Seyfried, T. N. (2025) · ONCOLOGIE · doi:10.1515/oncologie-2025-0238

Progressively exploring and assessing the prognosis of bladder urothelial cancer based on the microenvironment through the integration of multiple databases

Zou, X., 李彦锋, Peng, X., Gu, C., & Wang, Q. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1702311

Surface Avidity of Anionic Polypeptide Coatings on Layer‐by‐Layer Nanoparticles Target Cancer‐Associated Amino Acid Transporters

Pires, I. S., Billingsley, M. M., Gordon, E., Pickering, A. J., Cai, E., Esparza, G. J., Pryor, M. L., Stoneman, A. D., Kindopp, A., Irvine, D. J., et al. (2025) · Angewandte Chemie · doi:10.1002/ange.202519203

Comprehensive analysis of glycolysis and glycolysis-related mRNA signature associated with survival and immune response in bladder cancer

Wang, N., Xue, S., Li, Z., Cui, J., Dong, B., Liu, Y., Tao, J., Zhu, Z., Fan, Y.-H., Yu, S., et al. (2026) · Asian journal of urology · doi:10.1016/j.ajur.2025.07.003

<?A3B2 tlsb=-.02w?>Research progress on amino acid metabolic reprogramming in hepatocellular carcinoma <?A3B2 tlsb?>

You-Mei, L. I., Xin-Ru, Z. H. O. U., Jia-Jia, X. I. A., Liu, W., & Chun-Yu, W. A. N. G. (2026) · Shengming kexue · doi:10.3724/cbls.2026007

Amino Acids as Targets for Immunotherapy against Solid Tumors

da Costa, K. V. V., Passos, G. A., Botelho, R. J. S., Ruza, M. S. V., Dias-Lopes, G., & Silva, R. C. M. C. (2026) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-026-02050-y

The role of chemotherapy in fibroblast heterogeneity and immune infiltration in high-grade serous ovarian cancer

Licaj, M. (2021) · theses.fr (ABES) · doi:10.70675/1fec630ez02e2z4a03z92bbze061df7c86cc

Rôle de la matrice extracellulaire et des récepteurs à domaine discoïdine, DDR1 et DDR2, dans la résistance des cellules de mélanome aux thérapies ciblées

Berestjuk, I. (2019) · theses.fr (ABES) · doi:10.70675/9e2ac6eczf91cz4121za391z89c897cdc4a0

Étude des propriétés contractiles des fibroblastes du ganglion lymphatique au cours de la mise en place de la niche pré-métastatique du mélanome

Rovera, C. (2020) · theses.fr (ABES) · doi:10.70675/af78d3ecz2f22z4fe3zaafaz822245a1f598

The anti-tumoral effects of a low protein diet and of the IRE1α signaling

Turtos, A. M. (2022) · theses.fr (ABES) · doi:10.70675/fd90a3e8ze35az42fdzbd0ez966f12ddad22

Computational modeling of metabolic reprogramming in rheumatoid arthritis synovial fibroblasts and cancer- associated fibroblasts

Aghakhani, S. (2023) · theses.fr (ABES) · doi:10.70675/93acdc1azc8ccz4e31z912bz2470bed06094

Rôle du remodelage de la matrice extracellulaire dans la reprogrammation des cellules vasculaires pulmonaires au cours de l'hypertension artérielle pulmonaire

Rachedi, N. (2024) · doi:10.70675/ce19657cz09dez41d0z9ffezca0d3b10b914

Cellular death and division events at tissue interfaces: a chicken-or-the-egg situation

Karabay, E. T., & Katira, P. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-30048-6.00005-x

Dynamic mechanical three-way crosstalk at the interfaces of cancer cells, immune cells, like macrophages and stromal cells

Mierke, C. T. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-30048-6.00002-4

Cholesterol Reprograms Oxysterol Metabolism via the LOX1/CH25H/CYP7B1 Signaling Axis to Drive Multidrug Resistance in Colorectal Cancer

Cheng, H., Huang, L., Huang, J., Feng, J., Huang, K., Liu, M., & Ji, L. (2026) · Human Mutation · doi:10.1155/humu/3675889

Co-conditioning and parallel cell homing-driven pre-metastatic niche engineering: TGF-β-fuelled 3D microphysiological model for epithelial-mesenchymal transition in breast cancer

Vaishnavi, M., Kumari, M., Pal, S., Kaur, K., Kaity, S., Mandal, C., & Roy, S. (2026) · In vitro models · doi:10.1007/s44164-026-00119-9

Urinary proteome and metabolome uncover tumor microenvironment and cellular metabolism changes of renal clear cell carcinoma

Liu, X., Zhang, M., Zhao, Y., Dai, Y., Han, C., Chen, J., Sun, H. S., Guo, Z., Qi, F., Zhang, Y., et al. (2026) · British Journal of Cancer · doi:10.1038/s41416-026-03434-w

SQ-KFP: A Framework for Spatially Quantitative Metabolic Flux Analysis Enables Imaging the In Vivo Absolute Metabolic Enzymatic Reaction Rate

Liu, L., Xu, Y., Meng, X., Zhang, Z., Xu, Y., Wang, X., Lv, N., Wen, Z., Wang, F., Shao, W., et al. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.6c00605

Integrated multi-omics and single-cell analyses identify metabolic heterogeneity and therapeutic vulnerabilities in medullary thyroid cancer

Liu, C., Shen, C., Hou, Y., Du, Y., Liu, Y., Liu, D., Zhang, Y., Mao, X., Song, Y., Li, Z., et al. (2026) · British Journal of Cancer · doi:10.1038/s41416-026-03467-1

The Influence of Metabolism on the Autonomic Nerves on Tumor Occurrence and Development

王, 亭. (2026) · Advances in Clinical Medicine · doi:10.12677/acm.2026.1651986

CAF enhances pancreatic cancer EMT and chemo-resistance

Zhang, S., Ceng, Q., & Liu, M. (2026) · Scientia Sinica Vitae · doi:10.1360/ssv-2026-0104

MITF-Driven melanoma plasticity as a core mechanism of therapy resistance: integrating microenvironmental signaling, mechanotransduction, and metabolic reprogramming

Kisielewska, M., Suwała, S., Drąg‐Zalesińska, M., & Rembiałkowska, N. (2026) · Cell Cycle · doi:10.1080/15384101.2026.2684937

Engineered multivalent VCAM1–Fc decoys remodel ECM mechanosensing to suppress H3K18la–driven epigenetic programs and stemness in recurrent glioblastoma

Wang, Y., Ali, A., Zhu, J., Geng, Y., & Ma, C. (2026) · Cancer Letters · doi:10.1016/j.canlet.2026.218698

Crosstalk between m6A modification and metabolic reprogramming in colorectal cancer: from the immune microenvironment to clinical applications

Zhao, L., Yin, Z., Ji, C., Wu, Y., Gao, H., & Yuan, H. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1911067

Metabolic crosstalk between extracellular matrix, cancer-associated fibroblasts and tumor cells: drivers of tumor progression and therapeutic resistance

Wei, C., Sun, H., Long, J., Liu, X., Li, Q., & Cao, B. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.117308

The Crosstalk Between YAP/TAZ and Cancer Metabolism: From Mechanistic Insights to Drug Discovery

Gao, Y., Chen, M., Lin, S., Huang, M., & Jin, J. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27177537

Using Fluorescence Lifetime Imaging Microscopy to Probe the Metabolic Peritumor Microenvironment and Beyond

Najera, J., Chen, H., Howard, S. S., & Datta, M. (2026) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-026-00937-7

HGF/c-MET signaling induces glutamine metabolism in MET-amplified head and neck squamous cell carcinoma via MAPK/ERK-dependent induction of GLS-1

Hörner, M., Mersdorf, F., Burkard, N., Vollmer, A., Saravi, B., Renner, T., Volland, J., Kuebler, A. C., Schlegel, N., & Hartmann, S. (2026) · Medical Oncology · doi:10.1007/s12032-026-03409-0

Decoding the role of cancer-associated fibroblasts in cisplatin resistance of head and neck squamous cell carcinoma

Liu, D., Yu, D., Chen, M., Dai, T., Li, X., Su, D., 郑菊艳, & Zhang, Y. (2026) · iScience · doi:10.1016/j.isci.2026.117696

The HTRA1–Extracellular Matrix Axis in Health and Disease: From Pathological Remodeling to Therapeutic Opportunities in Fibrosis, Osteoarticular Disorders, and Cancer

Zong, L., Xiong, L., Wang, Y., Zhu, M., Li, J., Xu, J., 李虎年, & Li, Y. (2026) · Current Issues in Molecular Biology · doi:10.3390/cimb48100991

Cell jamming transition is regulated by mitochondrial pyruvate transport and endocytosis

Bermúdez, A., Latham, Z. D., Diaz, J., Yan, W., Chen, J., Bi, D., Goldstein, A. S., Hu, J. K., & Lin, N. Y. C. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2617216123

Same organ, divergent immunity: T-cell exhaustion versus stromal exclusion in hepatocellular carcinoma and intrahepatic cholangiocarcinoma

Chen, Y., Peng, T., Nie, H., & Hu, Y. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1944650

Mechano-metabolic control of multicellular morphogenesis

Bodineau, C., Bubna-Litic, M., Eicher, A. K., Pourquié, O., & Mongera, A. (2026) · Development · doi:10.1242/dev.204876

Mechano-metabolic coupling in the tumor microenvironment: from mechanotransduction to protein lactylation and metastatic cascades

Zhang, W., Chen, H., Fan, J., He, Y., & Liu, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1991810

Investigating a Potential Link Between Metabolic-Neurotrophic Coupling in Breast Tumor Innervation in Bioengineered Models

Ala-Kokko, N., Gregory, E., Woessner, A. E., Guan, B., Middleton, W., Johann, D. J., Rajaram, N., Muldoon, T. J., & Song, Y. H. (2026) · Cells · doi:10.3390/cells15211959

Metabolic crosstalk between extracellular matrix, cancer-associated fibroblasts and tumor cells: drivers of tumor progression and therapeutic resistance

Wei, C., Sun, H., Long, J., Liu, X., Li, Q., & Cao, B. (2026) · International Immunopharmacology · doi:10.1016/j.intimp.2026.117308

Tumor mechanics and metabolic dysfunction

Tung, J. C., Barnes, J. M., Desai, S. R., Sistrunk, C., Conklin, M. W., Schedin, P. S., Eliceiri, K. W., Keely, P. J., Seewaldt, V. L., & Weaver, V. M. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.11.020 · Cited by 126

Mechanical forces rewire metabolism in the tumor niche

Bertero, T., & Gaggioli, C. (2019) · Molecular & Cellular Oncology · doi:10.1080/23723556.2019.1592945 · Cited by 18

Dynamic links between mechanical forces and metabolism shape the tumor milieu

Bertolio, R., Napoletano, F., & Sal, G. D. (2023) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2023.102218 · Cited by 28

Metabolism Modulation of Cancer Cells on Varying Substrate Stiffnesses

Mah, E. J., Yee, A. F., & Digman, M. A. (2018) · Biophysical Journal · doi:10.1016/j.bpj.2017.11.147 · Cited by 1