The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.
Medicine in the Fourth Dimension
Open accessAbstract
The importance of circadian biology has rarely been considered in pre-clinical studies, and even more when translating to the bedside. Circadian biology is becoming a critical factor for improving drug efficacy and diminishing drug toxicity. Indeed, there is emerging evidence showing that some drugs are more effective at nighttime than daytime, whereas for others it is the opposite. This suggests that the biology of the target cell will determine how an organ will respond to a drug at a specific time of the day, thus modulating pharmacodynamics. Thus, it is now time that circadian factors become an integral part of translational research.
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Cites
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Self-citationCentral and Peripheral Circadian Clocks in Mammals
Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265
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Cited by
Wilkinson, M. J., Manoogian, E. N. C., Zadourian, A., Lo, H., Fakhouri, S., Shoghi, A., Wang, X., Fleischer, J. G., Navlakha, S., Panda, S., et al. (2020) · Cell Metabolism · doi:10.1016/j.cmet.2019.11.004 · Cited by 927
López-Otín, C., & Kroemer, G. (2021) · Cell · doi:10.1016/j.cell.2020.11.034 · Cited by 499
Circadian rhythms and disorders of the timing of sleep
Meyer, N., Harvey, A. G., Lockley, S. W., & Dijk, D.-J. (2022) · The Lancet · doi:10.1016/s0140-6736(22)00877-7 · Cited by 346
Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology
Martini, T., Naef, F., & Tchorz, J. S. (2023) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-031521-024831 · Cited by 113
Foundations of circadian medicine
Kramer, A., Lange, T., Spies, C., Finger, A.-M., Berg, D., & Oster, H. (2022) · PLOS Biology · doi:10.1371/journal.pbio.3001567 · Cited by 99
“This variation is explained by daily rhythms in pharmacokinetics and pharmacodynamics of most short-lived drugs [2,50,54].”
Background
Metadata
- Authors
- Cederroth, C. R., Albrecht, U., Bass, J., Brown, S. A., Dyhrfjeld-Johnsen, J., Gachon, F., Green, C. B., Hastings, M. H., Helfrich-Förster, C., Hogenesch, J. B., Lévi, F., Loudon, A., Lundkvist, G. B., Meijer, J. H., Rosbash, M., Takahashi, J. S., Young, M., & Canlon, B.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 30
- Issue
- 2
- Pages
- 238-250
- ISSN
- 1550-4131 (ISSN-L)
- OpenAlex
- W2965281435
- Cited by
- 359
- References
- 158
- FWCI
- 21.50
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Medicine in the Fourth Dimension. https://app.cochat.ai/papers/10.1016/j.cmet.2019.06.019
- The paper
- Cederroth, C. R., Albrecht, U., Bass, J., Brown, S. A., Dyhrfjeld-Johnsen, J., Gachon, F., Green, C. B., Hastings, M. H., Helfrich-Förster, C., Hogenesch, J. B., Lévi, F., Loudon, A., Lundkvist, G. B., Meijer, J. H., Rosbash, M., Takahashi, J. S., Young, M., & Canlon, B. (2019). Medicine in the Fourth Dimension. Cell Metabolism. https://doi.org/10.1016/j.cmet.2019.06.019
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
