The DOI matches its Crossref record; 121 of the 121 references it cites were found in a registry or an index.
Neuromodulation of neurons and synapses
Open accessAbstract
Neuromodulation underlies the flexibility of neural circuit operation and behavior. Individual neuromodulators can have divergent actions in a neuron by targeting multiple physiological mechanisms. Conversely, multiple neuromodulators may have convergent actions through overlapping targets. Additionally, the divergent and convergent neuromodulator actions can be unambiguously synergistic or antagonistic. Neuromodulation often entails balanced adjustment of nonlinear membrane and synaptic properties by targeting ion channel and synaptic dynamics rather than just excitability or synaptic strength. In addition, neuromodulators can exert effects at multiple timescales, from short-term adjustments of neuron and synapse function to persistent long-term regulation. This short review summarizes some highlights of the diverse actions of neuromodulators on ion channel and synaptic properties.
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Cites
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Cited by
Tang, J., Yuan, F., Shen, X., Wang, Z., Rao, M., He, Y., Sun, Y., Li, X., Zhang, W., Li, Y., et al. (2019) · Advanced Materials · doi:10.1002/adma.201902761 · Cited by 834
Synaptic Plasticity Forms and Functions
Magee, J. C., & Grienberger, C. (2020) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-090919-022842 · Cited by 806
Neuromodulation by the immune system: a focus on cytokines
Salvador, A. F., de Lima, K. A., & Kipnis, J. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-021-00508-z · Cited by 389
Single-cell transcriptomic evidence for dense intracortical neuropeptide networks
Smith, S. J., Sümbül, U., Graybuck, L. T., Collman, F., Seshamani, S., Gala, R., Gliko, O., Elabbady, L., Miller, J. A., Bakken, T. E., et al. (2019) · eLife · doi:10.7554/elife.47889 · Cited by 156
Dong, C., Zheng, Y., Long-Iyer, K., Wright, E. C., Li, Y., & Tian, L. (2022) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-110520-031137 · Cited by 99
Metadata
- Authors
- Nadim, F., & Bucher, D.
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 29
- Pages
- 48-56
- ISSN
- 0959-4388 (ISSN-L)
- OpenAlex
- W2001947879
- Cited by
- 338
- References
- 121
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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