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Cited by 108Reproductive Health and ContraceptionBlood Pressure and Hypertension StudiesMenopause: Health Impacts and Treatments

Combined oral contraceptive use among women with hypertension: a systematic review

Curtis, Kathryn M., Mohllajee, Anshu P., Martins, Summer L., Peterson, Herbert B.·2006·Contraception
DOI 10.1016/j.contraception.2005.08.005
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Abstract

Women with hypertension are at increased risk for cardiovascular events. Combined oral contraceptive (COC) use, even among low-dose users, has been associated with a small excess risk for cardiovascular events among healthy women. In this systematic review, we examined cardiovascular risks among COC users with hypertension. After searching MEDLINE for all articles published from 1966 through February 2005 relevant to COC use, hypertension and cardiovascular disease, we identified 25 articles for this review. Overall, these studies showed that hypertensive COC users were at higher risk for stroke and acute myocardial infarction (AMI) than hypertensive non-COC users, but that they were not at higher risk for venous thromboembolism (VTE). Women who did not have their blood pressure measured before initiating COC use were at higher risk for ischemic stroke and AMI, but not for hemorrhagic stroke or VTE, than COC users who did not have their blood pressure measured.

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Crossref · 10.1016/j.contraception.2005.08.005

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41 of 41 references verified0 citation errors · 0 not checkable

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  • Use of combined oral contraceptives in women with hypertension is associated with a much higher risk of ischaemic stroke (odds ratio 3.1 to 14.5) than in women with normal blood pressure taking non-combined oral contraceptives.

    “Use of combined oral contraceptives in women with hypertension women was associated with a much higher risk of myocardial infarction (odds ratio 6 to 68) and ischaemic stroke (odds ratio 3.1 to 14.5) than women with normal blood pressure taking non-combined oral contraceptives.84”

    From Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review (2020) · cites this paper as [84]

  • Use of combined oral contraceptives in women with hypertension is associated with a much higher risk of myocardial infarction (odds ratio 6 to 68) than in women with normal blood pressure taking non-combined oral contraceptives.

    “Use of combined oral contraceptives in women with hypertension women was associated with a much higher risk of myocardial infarction (odds ratio 6 to 68) and ischaemic stroke (odds ratio 3.1 to 14.5) than women with normal blood pressure taking non-combined oral contraceptives.84”

    From Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review (2020) · cites this paper as [84]

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Authors
Curtis, K. M., Mohllajee, A. P., Martins, S. L., & Peterson, H. B.
Affiliations
  • Centers for Disease Control and Prevention (US)
  • University of North Carolina at Chapel Hill (US)
Corresponding author
Curtis, Kathryn M.
ORCID
Venue
Contraception
Publisher
Elsevier BV
Published
2006-02
Volume
73
Issue
2
Pages
179-188
ISSN
0010-7824 (ISSN-L)
DOI
10.1016/j.contraception.2005.08.005
OpenAlex
W2163849500
Cited by
108
References
41
Citations by year
2026: 2 · 2025: 5 · 2024: 8 · 2023: 6 · 2022: 8 · 2021: 8 · 2020: 6 · 2019: 8 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 5 · 2013: 7 · 2012: 8
FWCI
0.63
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Contraception (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health
  • Centers for Disease Control and Prevention
  • National Institute of Child Health and Human Development
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords
combined oral contraceptives, hypertension, cardiovascular risk, stroke, myocardial infarction, venous thromboembolism, blood pressure measurement, hemorrhagic stroke, ischemic stroke
MeSH terms
Cardiovascular Diseases, Contraceptives, Oral, Combined, Female, Humans, Hypertension, Myocardial Infarction, Risk Factors, Venous Thrombosis, Stroke

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