The DOI matches its Crossref record; 50 of the 51 references it cites were found in a registry or an index.
Yeast metabolic engineering for hemicellulosic ethanol production
Abstract
Efficient fermentation of hemicellulosic sugars is critical for the bioconversion of lignocellulosics to ethanol. Efficient sugar uptake through the heterologous expression of yeast and fungal xylose/glucose transporters can improve fermentation if other metabolic steps are not rate limiting. Rectification of cofactor imbalances through heterologous expression of fungal xylose isomerase or modification of cofactor requirements in the yeast oxidoreductase pathway can reduce xylitol production while increasing ethanol yields, but these changes often occur at the expense of xylose utilization rates. Genetic engineering and evolutionary adaptation to increase glycolytic flux coupled with transcriptomic and proteomic studies have identified targets for further modification, as have genomic and metabolic engineering studies in native xylose fermenting yeasts.
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“Brennan et al. have devised an extraction method for glucose and xylose recovery from [C 2 C 1 im][MeCO 2 ] using boronates such as naphthalene-2-boronate.”
From Deconstruction of lignocellulosic biomass with ionic liquids (2013) · cites this paper as [182]
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Items 201–239 of 239
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Metadata
- Authors
- Van Vleet, J., & Jeffries, T.
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2009-06
- Volume
- 20
- Issue
- 3
- Pages
- 300-306
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W2068003115
- Cited by
- 241
- References
- 51
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 6 · 2020: 15 · 2019: 6 · 2018: 15 · 2017: 15 · 2016: 21 · 2015: 9 · 2014: 26 · 2013: 25 · 2012: 34
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Energy
- U.S. Department of Agriculture
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Keywords
- yeast metabolic engineering, xylose fermentation, xylose transporters, xylose isomerase, xylitol production, lignocellulosic biomass, glycolytic flux, xylose-fermenting yeast, heterologous expression
- MeSH terms
- Ethanol, Aldehyde Reductase, Pichia, Polysaccharides, Xylose, Yeasts, Protein Engineering, Aldose-Ketose Isomerases, D-Xylulose Reductase
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