An Updated Systematic Review on the Effects of Aerobic Exercise on Human Blood Lipid Profile
Abstract
Sedentary lifestyle and dyslipidemia are well-recognized risk factors for cardiovascular diseases (CVD). Changes in blood lipid profile (total cholesterol (TC), triglycerides, high-density lipoprotein [HDL], and low-density lipoprotein [LDL]) due to the exercise may be beneficial for decreasing CVD-related events. In this review we aimed to investigate the effect of different types of exercise on lipid profile components in people with different health conditions and age ranges. A systematic search was performed covering PubMed, Web of Science, and Google Scholar for English articles from 2010 until November 2021. Finally, 31 studies were included in our study. Results showed that exercise in younger individuals sometimes resulted in no significant changes of any of the variables or some of them; however, efficient improvement was observed in all studies of older and middle-age groups. In terms of health condition and gender; healthy individuals, overweight people, subjects with type 2 diabetes and obesity, and male participants found to have benefited more from the exercise. In patients with chronic kidney diseases lipid profile improvement was not significant. The cardiac rehabilitation program, particularly comprehensive cardiac rehabilitation, proved to be more beneficial than exercise alone in the case of cardiovascular patients and those at elevated risk of CVD. In conclusion exercise is beneficial in terms of improving lipid profile but for younger population, and thos…
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“This study employs a systematic literature review (SLR) (Doewes et al., 2023; Zadeh et al., 2023) to find, analyze, and combine findings from related studies.”
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- Authors
- Doewes, R. I., Gharibian, G., zadeh, F. A., Zaman, B. A., vahdat, S., & Akhavan-Sigari, R.
- Affiliations
- Sebelas Maret University (ID)
- Isfahan University of Medical Sciences (IR)
- Kerman University of Medical Sciences (IR)
- University of Duhok (IQ)
- Corresponding author
- Gharibian, Ghazal
- Venue
- Current Problems in Cardiology
- Publisher
- Elsevier BV
- Published
- 2023-05
- Volume
- 48
- Issue
- 5
- Pages
- 101108
- ISSN
- 0146-2806 (ISSN-L)
- OpenAlex
- W4206059524
- Cited by
- 85
- References
- 4
- Citations by year
- 2026: 12 · 2025: 12 · 2024: 17 · 2023: 27 · 2022: 17
- FWCI
- 4.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Problems in Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Isfahan University of Medical Sciences
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Keywords
- aerobic exercise, lipid profile, dyslipidemia, cardiovascular risk, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, cardiac rehabilitation, chronic kidney disease, type 2 diabetes, obesity, overweight, age differences, sex differences
- MeSH terms
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Humans, Lipids, Male, Middle Aged, Triglycerides, Exercise
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