Effects of Aerobic Exercise Alone on Lipids in Healthy East Asians: A Systematic Review and Meta-Analysis
Open accessAbstract
AIM: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. METHODS: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group-mean value at baseline in the exercise group)-(mean value at post-intervention in the control group-mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. RESULTS: =56.2%). When trials were limited to those involving moderate-intensity exercise (55%-69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity. CONCLUSIONS: The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week.
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Igarishi et al. conducted a pooled analysis reporting AT exhibits the largest participant numbers to date, but even this work has insufficient data to meet statistical futility.
“Igarishi et al. [18] conducted a pooled analysis, reporting AT exhibits the largest participant numbers to date, but even this work has insufficient data to meet statistical futility.”
From The Effect of Exercise Training on Blood Lipids: A Systematic Review and Meta-analysis (2025) · cites this paper as [18]
The Results (Study Selection; page unavailable) report that the authors pooled 25 studies of aerobic exercise in healthy East Asian adults. Neither the Results nor the Methods (Statistical Analyses; page unavailable) establish that this analysis had the largest participant numbers to date or assess whether its data met a statistical futility threshold. (LLM, conf=0.87)
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- Authors
- Igarashi, Y., Akazawa, N., & Maeda, S.
- Affiliations
- Osaka University of Health and Sport Sciences (JP)
- University of Tsukuba (JP)
- Corresponding author
- Igarashi, Yutaka
- Venue
- Journal of Atherosclerosis and Thrombosis
- Publisher
- Japan Atherosclerosis Society
- Published
- 2019-05-01
- Volume
- 26
- Issue
- 5
- Pages
- 488-503
- ISSN
- 1340-3478 (ISSN-L)
- 1880-3873
- PMC
- PMC6514176
- OpenAlex
- W2898740764
- Cited by
- 38
- References
- 60
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 3 · 2022: 7 · 2021: 9 · 2020: 5 · 2019: 1
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Journal of Atherosclerosis and Thrombosis (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Keywords
- aerobic exercise, serum lipids, lipoproteins, HDL cholesterol, LDL cholesterol, total cholesterol, triglycerides, East Asians, moderate-intensity exercise, exercise volume, healthy adults
- MeSH terms
- Heart Diseases, Humans, Lipids, Exercise, Asian People
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