Cited by 38Physical Activity and HealthCardiovascular and exercise physiologyLipoproteins and Cardiovascular Health

Effects of Aerobic Exercise Alone on Lipids in Healthy East Asians: A Systematic Review and Meta-Analysis

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Igarashi, Yutaka, Akazawa, Nobuhiko, Maeda, Seiji·2019·Journal of Atherosclerosis and Thrombosis

Abstract

AIM: The purpose of the current work was to review the effects of regular aerobic exercise on serum lipid and lipoprotein levels in East Asians using meta-analysis. METHODS: The randomized controlled trials analyzed involved healthy adults who were East Asians with a mean age ≥40 years, an exercise group that only performed regular aerobic exercise, and a control group that did not carry out exercise-related intervention; the trials indicated mean high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), or triglyceride (TG). The mean difference (MD) was defined as the difference (mean value at post-intervention in the exercise group-mean value at baseline in the exercise group)-(mean value at post-intervention in the control group-mean value at baseline in the control group) in HDL-C, LDL-C, TC, and TG and was calculated for each trial. The weighted MD was calculated with a random-effects model. RESULTS: =56.2%). When trials were limited to those involving moderate-intensity exercise (55%-69% of the maximum heart rate) or an exercise volume ≥150 min/week, the weighted MD in HDL-C, LDL-C, TC, and TG improved significantly and did not contain significant heterogeneity. CONCLUSIONS: The findings suggest that the ideal form of exercise to improve lipid and lipoprotein levels in East Asians is exercise of moderate-intensity and in a volume ≥150 min/week.

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  • Igarishi et al. conducted a pooled analysis reporting AT exhibits the largest participant numbers to date, but even this work has insufficient data to meet statistical futility.

    “Igarishi et al. [18] conducted a pooled analysis, reporting AT exhibits the largest participant numbers to date, but even this work has insufficient data to meet statistical futility.”

    From The Effect of Exercise Training on Blood Lipids: A Systematic Review and Meta-analysis (2025) · cites this paper as [18]

    The Results (Study Selection; page unavailable) report that the authors pooled 25 studies of aerobic exercise in healthy East Asian adults. Neither the Results nor the Methods (Statistical Analyses; page unavailable) establish that this analysis had the largest participant numbers to date or assess whether its data met a statistical futility threshold. (LLM, conf=0.87)

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1 of the 60 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

  1. [42]Uchikawa Y Miyai N Ito K Yabu M Ishii A Shiba M Utsumi M Arita M: Effects of walking exercise on cardiovascular risk parameters and arterial stiffness in middle-aged and elder subjects. Jpn J Appl physiol, 2010; 40: 185- 192 (Japanese)
  2. [50]Sugawara J Maeda S: Effect of aerobic exercise training central arterial hemodynamics in postmenopausal women. Research-aid Report, 2012; 27: 108- 117 (Japanese)
  3. [51]Uchikawa Y Nakamura C Miyai N Ito K Ishii A Utsumi M Arita M: Effects of walking in sand-beach on novel risk factors of cardiovascular disease in metabolic syndrome - randomized control design. Heart, 2012; 44: 799- 804 (Japanese)

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Authors
Igarashi, Y., Akazawa, N., & Maeda, S.
Affiliations
  • Osaka University of Health and Sport Sciences (JP)
  • University of Tsukuba (JP)
Corresponding author
Igarashi, Yutaka
Venue
Journal of Atherosclerosis and Thrombosis
Published
2019-05-01
Volume
26
Issue
5
Pages
488-503
ISSN
  • 1340-3478 (ISSN-L)
  • 1880-3873
OpenAlex
W2898740764
Cited by
38
References
60
Citations by year
2026: 3 · 2025: 2 · 2024: 8 · 2023: 3 · 2022: 7 · 2021: 9 · 2020: 5 · 2019: 1
FWCI
0.49
Type
journal article
Language
en
Open access
Licence
cc-by-nc-sa
Locations
  • Journal of Atherosclerosis and Thrombosis (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
Keywords
aerobic exercise, serum lipids, lipoproteins, HDL cholesterol, LDL cholesterol, total cholesterol, triglycerides, East Asians, moderate-intensity exercise, exercise volume, healthy adults
MeSH terms
Heart Diseases, Humans, Lipids, Exercise, Asian People

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