The DOI matches its Crossref record; 124 of the 130 references it cites were found in a registry or an index.
A review of opioid dependence treatment: Pharmacological and psychosocial interventions to treat opioid addiction
Abstract
Opioid dependence is a problem of national concern, especially with dramatically increased rates of abuse and dependence of prescription opioids. The current article provides an up-to-date review of the literature on opioid dependence treatment, with a focus on conclusions drawn by experts in the field (e.g., Cochrane reviews and meta-analyses) and methodologically rigorous studies (e.g., randomized controlled trials). We describe the major classes of drug treatments available, including opioid agonist (e.g., methadone, buprenorphine, LAAM), antagonist (e.g., naltrexone) and non-opioid pharmacotherapies (e.g., alpha2 adrenergic agonists). These treatments are discussed in the context of detoxification and long term treatment options such as abstinence-based and maintenance strategies. We review the state of the literature as to prevention of opioid overdose and discuss the widespread problem of comorbidity among opioid-dependent populations. We also focus prominently on evidence for inclusion of psychosocial approaches in treatment regimens, either as stand-alone or in conjunction with psychopharmacological options.
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“There is a dearth of research investigating the efficacy of psychosocial treatments in reducing opioid use among people living with chronic pain.42,43”
Citations
Cites
2 retracted
Psychosocial treatment for opiate abuse and dependence
Mayet, S., Farrell, M., Ferri, M., Amato, L., & Davoli, M. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004330.pub2 · Cited by 106
RetractedPsychosocial treatment for opiate abuse and dependence
Mayet, S., Farrell, M., Ferri, M., Davoli, M., & Amato, L. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004330 · Cited by 12
RetractedMonitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings
Johnston, L. D., O’Malley, P. M., Bachman, J. G., & Schulenberg, J. E. (2003) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1037/e560352009-001 · Cited by 6,930
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Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors
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Mattick, R. P., Breen, C. L., Kimber, J., & Davoli, M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002207.pub4 · Cited by 2,312
Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence
Mattick, R. P., Breen, C., Kimber, J., & Davoli, M. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002209.pub2 · Cited by 1,654
Volume, I. I. (2017) · Institute for Social Research eBooks · doi:10.3998/2027.42/139710 · Cited by 1,369
A Meta-Analytic Review of Psychosocial Interventions for Substance Use Disorders
Dutra, L., Stathopoulou, G., Basden, S. L., Leyro, T. M., Powers, M. B., & Otto, M. W. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06111851 · Cited by 1,287
Results from the 2003 National Survey on Drug Use and Health: National Findings
(2004) · PsycEXTRA Dataset · doi:10.1037/e400442005-001 · Cited by 1,245
Research works printed but not linked: 2
- Johnston, 2008, Monitoring the future national survey results on drug use, 1975–2007, Vol. 1.
- Maremmani, 2003, Dual diagnosis heroin addicts. The clinical and therapeutic aspects, Heroin Addiction and Related Clinical Problems, 5, 7
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Williams, D. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316275047.031 · Cited by 1
Williams, D. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316275047.006
Williams, D. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316275047.014
Darwinian Hedonism and Unhealthy Behavior
Williams, D. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316275047.023
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Williams, D. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316275047.005
Harm Reduction for Injection Drug Users
Kuo, I. C., & Phillips, G. (2018) · Springer eBooks · doi:10.1007/978-1-4939-7101-5_110
Feit, J., Gorzelańczyk, E. J., Mrówczyńska, E., Nowińska, E., & Pasgreta, K. (2012) · Medical and Biological Sciences · doi:10.2478/v10251-012-0028-4
Williams, D. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781316275047.034
Yunusoğlu, O., KÖSE, Ç., Shahzadi, A., Demir, B., Önal, B., Özyazgan, S., & Akkan, A. G. (2022) · Archives of Current Medical Research · doi:10.47482/acmr.1159319
A Grounded Theory of the Process of Healing From Opioid Addiction
McDonald, J. E., Cook, J. M., & Tocci, B. A. (2023) · Journal of Humanistic Psychology · doi:10.1177/00221678221143546
Şibar, S., Karasu, O., DENİZ, E., DEMİRBAŞ, B., & Küçükkarapınar, M. (2023) · Turkiye Klinikleri Journal of Medical Sciences · doi:10.5336/medsci.2022-93637
Long-Term Treatment of Opioid Use Disorder with Medications
Wolfgang, A. S., Weimer, M. B., Na, P. J., Fiellin, D. A., & Muvvala, S. B. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197618431.013.23
Psychosocially-Assisted Pharmacological Treatment of Opioid Dependent Adults: A Systematic Review
Wayah, S. B., Waziri, P. M., Onyebuchi, C. M., Yahaya, G., & Chindo, B. A. (2022) · Ibom Medical Journal · doi:10.61386/imj.v15i3.264
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Opioid Addiction Following Surgery
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Laurenz, L. J., & Thomasius, R. (2023) · Springer eBooks · doi:10.1007/978-3-662-65267-1_25
Liu, L., Tang, Z., Li, X., & Wing, H.-C. (2024) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2024.2315316
Madde Kullanan Bireylerin Sokaktan İlaç Alma Davranışının İncelenmesi
Aktürk, İ., Karaman, H., Altıntaş, F., & Yaman, Ö. M. (2024) · Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi · doi:10.37989/gumussagbil.1366988
Nayan, N. F. S., Kadri, R., Bakar, N. I. N. A., & Sabri, S. H. (2024) · International Journal of Education Psychology and Counseling · doi:10.35631/ijepc.954037
Santaella-Tenorio, J., Rivera‐Aguirre, A., Hepler, S. A., Kline, D., Cantor, J., DeYoreo, M., Martins, S. S., Krawczyk, N., & Cerdá, M. (2023) · Epidemiology · doi:10.1097/ede.0000000000001816
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Spinal Mechanisms of Hyperalgesic Priming
Kim, J. (2015) · UA Campus Repository (The University of Arizona)
Treatment Outcomes for Opiate Addicted Pregnant Women
Parr, R., & Jennifer, L. (2015) · UKnowledge (University of Kentucky)
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Assessment of Cognitive Impairment Between Natural and Synthetic Opioid Users
Aluna, A., Kumar, P., Mahajan, N. S., Mahajan, R., & Miglani, M. (2026) · Journal of Pharmacy And Bioallied Sciences · doi:10.4103/jpbs.jpbs_984_25
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BindingDB Entry 50047841: Combined Interactions with I
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Metadata
- Authors
- Veilleux, J. C., Colvin, P. J., Anderson, J., York, C., & Heinz, A. J.
- Affiliations
- University of Illinois Chicago (US)
- Corresponding author
- Veilleux, Jennifer C.
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 30
- Issue
- 2
- Pages
- 155-166
- ISSN
- 0272-7358 (ISSN-L)
- OpenAlex
- W2038833041
- Cited by
- 336
- References
- 130
- Citations by year
- 2026: 2 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 21 · 2021: 12 · 2020: 24 · 2019: 62 · 2018: 24 · 2017: 22 · 2016: 18 · 2015: 24 · 2014: 29 · 2013: 22 · 2012: 20
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- opioid use disorder, opioid dependence treatment, pharmacological interventions, psychosocial interventions, methadone, buprenorphine, LAAM, naltrexone, alpha-2 adrenergic agonists, opioid agonists, opioid antagonists, opioid detoxification, abstinence-based treatment, maintenance therapy, opioid overdose prevention, comorbidities, prescription opioid abuse
- MeSH terms
- Biofeedback, Psychology, Humans, Narcotic Antagonists, Opioid-Related Disorders, Narcotics, Self-Help Groups, Cognitive Behavioral Therapy, Prevalence, Adrenergic Agents
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