The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index.
The Hypermetabolic Response to Burn Injury and Interventions to Modify this Response
Open accessAbstract
SYNOPSIS Severe burn injury is followed by a profound hypermetabolic response that persists up to 24 months after injury. It is mediated by up to 50-fold elevations in plasma catecholamines, cortisol and inflammatory cells that lead to whole body catabolism, elevated resting energy expenditures and multi-organ dysfunction. All of these metabolic and physiologic derangements prevent full rehabilitation and acclimatization of burn survivors back into society. Modulation of the response by early excision and grafting of burn wounds, thermoregulation, early and continuous enteral feeding with high protein–high carbohydrate feedings and pharmacologic treatments have markedly decreased morbidity.
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Cites
Intensive insulin therapy in critically ill patients.
Van den Berghe, G., Wouters, P., Weekers, F., Verwaest, C., Bruyninckx, F., Schetz, M., Vlasselaers, D., Ferdinande, P., Lauwers, P., & Bouillon, R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011300 · Cited by 9,977
Martin, R. (1986) · Medical Entomology and Zoology · Cited by 8,752
Effect of Atenolol on Mortality and Cardiovascular Morbidity after Noncardiac Surgery
Mangano, D. T., Layug, E. L., Wallace, A., & Tateo, I. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612053352301 · Cited by 1,694
Stress and the General Adaptation Syndrome
Selye, H. (1950) · BMJ · doi:10.1136/bmj.1.4667.1383 · Cited by 1,481
Increased mortality associated with growth hormone treatment in critically ill adults
Takala, J., Ruokonen, E., Webster, N. R., Nielsen, M. S., Zandstra, D. F., Vundelinckx, G., & Hinds, C. J. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909093411102 · Cited by 1,023
INCREASED MORTALITY ASSOCIATED WITH GROWTH HORMONE TREATMENT IN CRITICALLY ILL ADULTS
Akala, J. U. T., Uokonen, E. S. R., Igel, N., Ebster, R. W., Ielsen, M. I. S. N., Andstra, D. U. F. Z., Undelinckx, G. U. V., & Inds, H. J. H. (1999) · Cited by 889
Catecholamines: Znediator of the Hypermetabolic Response to Thermal Injury
WILMORE, D. W., LONG, J. M., MASON, A. D., SKREEN, R. W., & PRUITT, B. A. (1974) · Annals of Surgery · doi:10.1097/00000658-197410000-00031 · Cited by 753
Pathophysiologic Response to Severe Burn Injury
Jeschke, M. G., Chinkes, D. L., Finnerty, C. C., Kulp, G., Suman, O. E., Norbury, W. B., Branski, L. K., Gauglitz, G. G., Mlcak, R. P., & Herndon, D. N. (2008) · Annals of Surgery · doi:10.1097/sla.0b013e3181856241 · Cited by 695
Self-citationAmerican Burn Association Consensus Conference to Define Sepsis and Infection in Burns
Greenhalgh, D. G., Saffle, J. R., Holmes, J. H., Gamelli, R. L., Palmieri, T. L., Horton, J. W., Tompkins, R. G., Traber, D. L., Mozingo, D. W., Deitch, E. A., et al. (2007) · Journal of Burn Care & Research · doi:10.1097/bcr.0b013e3181599bc9 · Cited by 695
Self-citationReversal of Catabolism by Beta-Blockade after Severe Burns
Herndon, D. N., Hart, D. W., Wolf, S. E., Chinkes, D. L., & Wolfe, R. R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa010342 · Cited by 639
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Cited by
Burn wound healing and treatment: review and advancements
Rowan, M. P., Cancio, L. C., Elster, E. A., Burmeister, D. M., Rose, L. F., Natesan, S., Chan, R. K., Christy, R. J., & Chung, K. K. (2015) · Critical Care · doi:10.1186/s13054-015-0961-2 · Cited by 1,015
Burns: Pathophysiology of Systemic Complications and Current Management
Nielson, C. B., Duethman, N. C., Howard, J. M., Moncure, M., & Wood, J. G. (2017) · Journal of Burn Care & Research · doi:10.1097/bcr.0000000000000355 · Cited by 367
Starke, J., Schneider, H., Alteheld, B., Stehle, P., & Meier, R. (2011) · Clinical Nutrition · doi:10.1016/j.clnu.2010.07.021 · Cited by 156
Metadata
- Authors
- Williams, F. N., Herndon, D. N., & Jeschke, M. G.
- Venue
- Clinics in Plastic Surgery
- Publisher
- Elsevier BV
- Published
- 2009-10
- Volume
- 36
- Issue
- 4
- Pages
- 583-596
- ISSN
- 0094-1298 (ISSN-L)
- OpenAlex
- W1986937268
- Cited by
- 258
- References
- 119
- FWCI
- 2.88
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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