Unmasking Transcriptional Heterogeneity in Senescent Cells
Hernandez-Segura, Alejandra, de Jong, Tristan V., Melov, Simon, Guryev, Victor, Campisi, Judith, Demaria, Marco·2017·Current Biology
Cited by (921)
Items 101–200 of 921
- Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancerMartina Troiani, Manuel Colucci, Mariantonietta D’Ambrosio, Ilaria Guccini, Emiliano Pasquini, Angelica Varesi, Aurora Valdata, Simone Mosole, Ajinkya Revandkar, Giuseppe Attanasio et al. · 2022 · Nature Communications
- Senescent cell population with ZEB1 transcription factor as its main regulator promotes osteoarthritis in cartilage and meniscusHannah Swahn, Kun Li, Tomas Duffy, Merissa Olmer, Darryl D. DʼLima, Tony S. Mondala, Padmaja Natarajan, Steven Robert Head, Martin Lotz · 2022 · Annals of the Rheumatic Diseases
- Senolytics and Senostatics: A Two-Pronged Approach to Target Cellular Senescence for Delaying Aging and Age-Related Diseases.Chanhee Kang · 2019 · Europe PMC (PubMed Central)
- Lipids as Regulators of Cellular SenescenceShruthi Hamsanathan, Aditi U. Gurkar · 2022 · Frontiers in Physiology
- Cellular senescence and cardiovascular diseases: moving to the “heart” of the problemKonstantinos Evangelou, Panagiotis V. S. Vasileiou, Angelos Papaspyropoulos, Orsalia Georgia Hazapis, Russell Petty, Marco Demaria, Vassilis G. Gorgoulis · 2022 · Physiological Reviews
- Pharmacological CDK4/6 inhibition reveals a p53‐dependent senescent state with restricted toxicityWang, Boshi, Varela‐Eirin, Marta, Brandenburg, Simone M, Hernandez‐Segura, Alejandra, van Vliet, Thijmen, Jongbloed, Elisabeth M, Wilting, Saskia M, Ohtani, Naoko, Jager, Agnes, Demaria, Marco · 2022 · The EMBO Journal
- Cellular senescence in lung cancer: Molecular mechanisms and therapeutic interventionsSaurav Kumar Jha, Gabriele De Rubis, Shankar Raj Devkota, Yali Zhang, Radhika Adhikari, Laxmi Akhileshwar Jha, Kunal Bhattacharya, Samir Mehndiratta, Gaurav Gupta, Sachin Kumar Singh et al. · 2024 · Ageing Research Reviews
- Mechanisms and significance of therapy-induced and spontaneous senescence of cancer cellsJustyna Mikuła‐Pietrasik, Arkadiusz Andrzej Niklas, Paweł Uruski, Andrzej Tykarski, Krzysztof Książek · 2019 · Cellular and Molecular Life Sciences
- Asynchronous, contagious and digital agingRando, Thomas A., Wyss-Coray, Tony · 2021 · Nature Aging
- A common signature of cellular senescence; does it exist?Ewa Sikora, Anna Bielak-Żmijewska, Grażyna Mosieniak · 2021 · Ageing Research Reviews
- Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic CancerJad I. Belle, Devashish Sen, John M. Baer, Xiuting Liu, Varintra E. Lander, Jiayu Ye, Blake E. Sells, Brett L. Knolhoff, Faiz F. Ahmad, Liang‐I Kang et al. · 2024 · Cancer Discovery
- Decoding the Transcriptional Response to Ischemic Stroke in Young and Aged Mouse BrainAndrovic, Peter, Kirdajova, Denisa, Tureckova, Jana, Zucha, Daniel, Rohlova, Eva, Abaffy, Pavel, Kriska, Jan, Valny, Martin, Anderova, Miroslava, Kubista, Mikael et al. · 2020 · Cell Reports
- The right time for senescenceParamos-de-Carvalho, Diogo, Jacinto, Antonio, Saúde, Leonor · 2021 · eLife
- The landscape of human tissue and cell type specific expression and co-regulation of senescence genesXu, Peng, Wang, Minghui, Song, Won-min, Wang, Qian, Yuan, Guo-Cheng, Sudmant, Peter H., Zare, Habil, Tu, Zhidong, Orr, Miranda E., Zhang, Bin · 2022 · Molecular Neurodegeneration
- Systemic induction of senescence in young mice after single heterochronic blood exchangeJeon, Ok Hee, Mehdipour, Melod, Gil, Tae-Hwan, Kang, Minha, Aguirre, Nicholas W., Robinson, Zachery R., Kato, Cameron, Etienne, Jessy, Lee, Hyo Gyeong, Alimirah, Fatouma et al. · 2022 · Nature Metabolism
- Cell senescence in liver diseases: pathological mechanism and theranostic opportunitySanfeliu-Redondo, David, Gibert-Ramos, Albert, Gracia-Sancho, Jordi · 2024 · Nature Reviews Gastroenterology & Hepatology
- Senescent Cells: A Therapeutic Target in Cardiovascular DiseasesMasayoshi Suda, Karl H Paul, Tohru Minamino, Jordan D. Miller, Amir Lerman, Georgina M. Ellison, Tamar Tchkonia, James L. Kirkland · 2023 · Cells
- A Proteomic Atlas of Senescence-Associated Secretomes for Aging Biomarker Development2019
- Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapiesMariantonietta D’Ambrosio, Jesús Gil · 2023 · Developmental Cell
- Cellular Senescence and Ageing: Mechanisms and InterventionsAndreas Mylonas, Ana O’Loghlen · 2022 · Frontiers in Aging
- Regulation of senescence and the SASP by the transcription factor C/EBPβSalotti, Jacqueline, Johnson, Peter F. · 2019 · Experimental Gerontology
- Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticityWouter A. J. Vints, Oron Levin, Hakuei Fujiyama, Jeanine Verbunt, Nerijus Masiulis · 2022 · Frontiers in Neuroendocrinology
- Skin-Aging Pigmentation: Who Is the Real Enemy?Jin Cheol Kim, Tae Jun Park, Hee Young Kang · 2022 · Cells
- Targeting senescent cells for a healthier longevity: the roadmap for an era of global agingSun, Yu, Li, Qingfeng, Kirkland, James L · 2022 · Life Medicine
- Caloric restriction and cellular senescenceFontana, Luigi, Nehme, Jamil, Demaria, Marco · 2018 · Mechanisms of Ageing and Development
- Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitorsMeharena, Hiruy S., Marco, Asaf, Dileep, Vishnu, Lockshin, Elana R., Akatsu, Grace Y., Mullahoo, James, Watson, L. Ashley, Ko, Tak, Guerin, Lindsey N., Abdurrob, Fatema et al. · 2022 · Cell Stem Cell
- Cellular hallmarks of aging emerge in the ovary prior to primordial follicle depletionAnsere, Victor A., Ali-Mondal, Samim, Sathiaseelan, Roshini, Garcia, Driele N., Isola, José V.V., Henseb, Jéssica D., Saccon, Tatiana D., Ocañas, Sarah R., Tooley, Kyla B., Stout, Michael B. et al. · 2021 · Mechanisms of Ageing and Development
- Radiation-induced senescence: therapeutic opportunitiesJae Ho Kim, Stephen L. Brown, Marcia N. Gordon · 2023 · Radiation Oncology
- Send in the senolyticsElie Dolgin · 2020 · Nature Biotechnology
- Premature cell senescence in human skin: Dual face in chronic acquired pigmentary disordersBarbara Bellei, Mauro Picardo · 2019 · Ageing Research Reviews
- Tumor microenvironment and cellular senescence: Understanding therapeutic resistance and harnessing strategiesHanxin Liu, Huifang Zhao, Yu Sun · 2021 · Seminars in Cancer Biology
- Novel insights from a multiomics dissection of the Hayflick limitChan, Michelle, Yuan, Han, Soifer, Ilya, Maile, Tobias M, Wang, Rebecca Y, Ireland, Andrea, O'Brien, Jonathon J, Goudeau, Jérôme, Chan, Leanne JG, Vijay, Twaritha et al. · 2022 · eLife
- Cellular senescence in cancer: clinical detection and prognostic implicationsDomen, Andreas, Deben, Christophe, Verswyvel, Jasper, Flieswasser, Tal, Prenen, Hans, Peeters, Marc, Lardon, Filip, Wouters, An · 2022 · Journal of Experimental & Clinical Cancer Research
- Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell populationDaryle J. DePianto, Jason A. Vander Heiden, Katrina B. Morshead, Kai-Hui Sun, Zora D. Modrusan, Grace Teng, Paul J. Wolters, Joseph R. Arron · 2021 · JCI Insight
- Senescence-associated secretory phenotype and its impact on oral immune homeostasisZiqi Yue, Lulingxiao Nie, Pengfei Zhao, Ning Ji, Ga Liao, Qi Wang · 2022 · Frontiers in Immunology
- Cellular senescence of renal tubular epithelial cells in acute kidney injuryJuan Chen, Huhai Zhang, Xiangling Yi, Qian Dou, Xin Yang, Jia Chen, Jia Chen, Kehong Chen · 2024 · Cell Death Discovery
- Dissecting primary and secondary senescence to enable new senotherapeutic strategiesTesfahun Dessale Admasu, Michael J. Rae, Alexandra Stolzing · 2021 · Ageing Research Reviews
- Fisetin as a senotherapeutic agent: Evidence and perspectives for age-related diseasesJuliette Tavenier, Jan Olof Nehlin, Morten Baltzer Houlind, Lene Juel Rasmussen, Tamar Tchkonia, James L. Kirkland, Ove Andersen, Line Jee Hartmann Rasmussen · 2024 · Mechanisms of Ageing and Development
- Senescent Tumor Cells Build a Cytokine Shield in Colorectal CancerYong Won Choi, Young Hwa Kim, Seung Yeop Oh, Kwang Wook Suh, Young‐Sam Kim, Ga‐Yeon Lee, Jung Eun Yoon, Soon Sang Park, Young‐Kyoung Lee, Yoo Jung Park et al. · 2021 · Advanced Science
- Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron contentFábio Papes, Antônio Pedro Camargo, Janaína Sena de Souza, Vinicius Miessler de Andrade Carvalho, Ryan A. Szeto, Erin LaMontagne, José Ricardo Teixeira Júnior, Simoni Helena Avansini, Sandra M. Sánchez-Sánchez, Thiago Seike Nakahara et al. · 2022 · Nature Communications
- Suppression of p16 alleviates the senescence-associated secretory phenotype2021
- Aging Biomarkers: From Functional Tests to Multi‐Omics ApproachesKseniya S. Kudryashova, Ksenia Burka, Anton Y. Kulaga, Nataliya S. Vorobyeva, Brian Keith Kennedy · 2020 · PROTEOMICS
- A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganizationChristos Zampetidis, Panagiotis Galanos, Andriani Angelopoulou, Yajie Zhu, Aikaterini Polyzou, Timokratis Karamitros, Athanassios Kotsinas, Nefeli Lаgopati, Ioanna Mourkioti, Reza Mirzazadeh et al. · 2021 · Molecular Cell
- Short-term gain, long-term pain: the senescence life cycle and cancerChan, Adelyne Sue Li, Narita, Masashi · 2019 · Genes & Development
- Non-cell autonomous effects of the senescence-associated secretory phenotype in cancer therapy.Saleh, Tareq, Tyutynuk-Massey, Liliya, Cudjoe, Emmanuel K., Idowu, Michael O., Landry, Joseph W., Gewirtz, David A. · 2018 · Frontiers in Oncology
- Potential Regulators of the Senescence-Associated Secretory Phenotype During Senescence and AgingXiaojuan Han, Qing Lei, Jiamei Xie, Huanhuan Liu, Jing Li, Xiaohua Zhang, Tianying Zhang, Xingchun Gou · 2022 · The Journals of Gerontology Series A
- ATF3 drives senescence by reconstructing accessible chromatin profilesZhang, Chao, Zhang, Xuebin, Huang, Li, Guan, Yiting, Huang, Xiaoke, Tian, Xiao‐Li, Zhang, Lijun, Tao, Wei · 2021 · Aging Cell
- Cellular Senescence and the Kidney: Potential Therapeutic Targets and ToolsSebastian N. Knoppert, Floris A. Valentijn, Tri Q. Nguyen, Roel Goldschmeding, Lucas L. Falke · 2019 · Frontiers in Pharmacology
- Senescent Microglia: The Key to the Ageing Brain?Greenwood, Eleanor K., Brown, David R. · 2021 · International Journal of Molecular Sciences
- Transcriptome signature of cellular senescenceCasella, Gabriel, Munk, Rachel, Kim, Kyoung Mi, Piao, Yulan, De, Supriyo, Abdelmohsen, Kotb, Gorospe, Myriam · 2019 · Nucleic Acids Research
- Local senolysis in aged mice only partially replicates the benefits of systemic senolysisFarr, Joshua N., Saul, Dominik, Doolittle, Madison L., Kaur, Japneet, Rowsey, Jennifer L., Vos, Stephanie J., Froemming, Mitchell N., Lagnado, Anthony B., Zhu, Yi, Weivoda, Megan et al. · 2023 · Journal of Clinical Investigation
- Emerging insights in senescence: pathways from preclinical models to therapeutic innovationsLuke Mansfield, Valentina Ramponi, Kavya Gupta, Thomas Stevenson, Abraham Binoy Mathew, Agian Jeffilano Barinda, Florencia Herbstein, Samir Morsli · 2024 · npj Aging
- Targeting dual signalling pathways in concert with immune checkpoints for the treatment of pancreatic cancerErik S. Knudsen, Vishnu Muthuraj Kumarasamy, Sejin Chung, Amanda Ruiz, Paris J. Vail, Stephanie L. Tzetzo, Jin Wu, Ram Nambiar, Jared Sivinski, Shailender Singh Chauhan et al. · 2020 · Gut
- Ranking Biomarkers of Aging by Citation Profiling and Effort ScoringAlexander Hartmann, Christiane Hartmann, Riccardo Secci, Andreas Hermann, Georg Fuellen, Michael Walter · 2021 · Frontiers in Genetics
- The hallmarks of aging as a conceptual framework for health and longevity researchAntonio G. Tartiere, José M.P. Freije, Carlos López-Otı́n · 2024 · Frontiers in Aging
- Cellular senescence and the host immune system in aging and age-related disordersYvonne Giannoula, Guido Kroemer, Federico Pietrocola · 2023 · Biomedical Journal
- Strategies for senolytic drug discoveryHelen Power, Peter Valtchev, Fariba Dehghani, Aaron Schindeler · 2023 · Aging Cell
- The connection between aging, cellular senescence and gut microbiome alterations: A comprehensive reviewD.S. Jang, Ji‐Won Shin, Eunha Shim, Naoko Ohtani, Ok Hee Jeon · 2024 · Aging Cell
- Dormant cancer cells: programmed quiescence, senescence, or both?Kevin Truskowski, Sarah R. Amend, Kenneth J. Pienta · 2023 · Cancer and Metastasis Reviews
- Coordinate regulation of the senescent state by selective autophagyYeonghyeon Lee, Jae‐Jin Kim, Mi-Sung Kim, Kwon Yoojin, Sanghee Shin, Hyerim Yi, Hyeonkyeong Kim, Moon Jong Chang, Chong Bum Chang, Seung‐Baik Kang et al. · 2021 · Developmental Cell
- Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19Jan Brábek, Milan Jakubek, F.M.D. Vellieux, Jiří Novotný, Michal Kolář, Lukáš Lacina, Pavol Szabó, Karolína Strnadová, Daniel Rösel, Barbora Dvořánková et al. · 2020 · International Journal of Molecular Sciences
- Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancerAnna J. Wiecek, Stephen J. Cutty, Daniel Kornai, Mario Parreno-Centeno, Lucie E. Gourmet, Guidantonio Malagoli Tagliazucchi, Daniel H. Jacobson, Ping Zhang, Lingyun Xiong, Gareth L. Bond et al. · 2023 · Genome biology
- Cellular senescence and kidney agingNikolai Rex, Anette Melk, Roland Schmitt · 2023 · Clinical Science
- Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine DysfunctionMasayoshi Suda, Karl H Paul, Utkarsh Tripathi, Tohru Minamino, Tamar Tchkonia, James L. Kirkland · 2024 · Endocrine Reviews
- Unveiling the cell-type-specific landscape of cellular senescence through single-cell transcriptomics using SenePySanborn, Mark A., Wang, Xinge, Gao, Shang, Dai, Yang, Rehman, Jalees · 2025 · Nature Communications
- Cell senescence in neuropathology: A focus on neurodegeneration and tumoursGabriela Carreno, Romain Guiho, Juan Pedro Martı́nez-Barberá · 2020 · Neuropathology and Applied Neurobiology
- The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotypeMarta Montes, Michał Lubas, Frederic Schrøder Arendrup, Bettina Mentz, Neha Rohatgi, Sarunas Tumas, Lea Mørch Harder, Anders J. Skanderup, Jens Andersen, Anders Henrik Lund · 2021 · Nature Communications
- A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolismKhaled Tighanimine, José Américo Nabuco Leva Ferreira de Freitas, Ivan Nemazanyy, Alexia Bankolé, Delphine Benarroch, Susanne Brodesser, Grégory R G Doré, Lucas J. Robinson, Paule Bénit, Sophia Ladraa et al. · 2024 · Nature Metabolism
- The power of proteomics to monitor senescence-associated secretory phenotypes and beyond: toward clinical applicationsBasisty, Nathan, Kale, Abhijit, Patel, Sandip, Campisi, Judith, Schilling, Birgit · 2020 · Expert Review of Proteomics
- Feed-forward regulation between cellular senescence and immunosuppression promotes the aging process and age-related diseasesAntero Salminen · 2021 · Ageing Research Reviews
- Senescent macrophages in the human adipose tissue as a source of inflammagingGiulia Matacchione, Jessica Perugini, Eleonora Di Mercurio, Jacopo Sabbatinelli, Francesco Prattichizzo, Martina Senzacqua, Gianluca Storci, Christian Dani, Giovanni Lezoche, Mario Guerrieri et al. · 2022 · GeroScience
- Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in miceScarlett Acklin, Manchao Zhang, Wuying Du, Xin Zhao, Matthew D. Plotkin, Jianhui Chang, Judith Campisi, Daohong Zhou, Fen Xia · 2020 · Scientific Reports
- In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspanRui Ribeiro, Joana Catarina Macedo, Madalena M Costa, Vladimir Ustiyan, Anastasia V. Shindyapina, Alexander Tyshkovskiy, Rita N. Gomes, José Pedro Castro, Tanya V. Kalin, Francisco Vasques‐Nóvoa et al. · 2022 · Nature Aging
- Targeting tumor cell senescence and polyploidy as potential therapeutic strategiesTareq Saleh, Valerie J. Carpenter, Sarah Bloukh, David A. Gewirtz · 2020 · Seminars in Cancer Biology
- Exploring the Communication of the SASP: Dynamic, Interactive, and Adaptive Effects on the MicroenvironmentJoëlle Giroud, Inès Bouriez, Hugo Paulus, Albin Pourtier, Florence Debacq‐Chainiaux, Olivier Pluquet · 2023 · International Journal of Molecular Sciences
- Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologiesCherry, Christopher, Andorko, James I., Krishnan, Kavita, Mejías, Joscelyn C., Nguyen, Helen Hieu, Stivers, Katlin B., Gray-Gaillard, Elise F., Ruta, Anna, Han, Jin, Hamada, Naomi et al. · 2023 · GeroScience
- SETD1A protects from senescence through regulation of the mitotic gene expression programKen Tajima, Satoru Matsuda, Toshifumi Yae, Benjamin Jacob Drapkin, Robert Tyler Morris, Myriam Boukhali, Kira Niederhoffer, Valentine Comaills, Taronish D. Dubash, Linda T. Nieman et al. · 2019 · Nature Communications
- Cellular senescenceMarta Varela-Eirín, Marco Demaria · 2022 · Current Biology
- Pro- and anti-tumorigenic functions of the senescence-associated secretory phenotypeLena Lau, Gregory David · 2019 · Expert Opinion on Therapeutic Targets
- Role of Senescence and Aging in SARS-CoV-2 Infection and COVID-19 DiseaseSeodhna M. Lynch, Guangran Guo, David S. Gibson, Anthony J. Bjourson, Taranjit Singh · 2021 · Cells
- mRNA methylation in cell senescenceGabriel Casella, Dimitrios Tsitsipatis, Kotb Abdelmohsen, Myriam Gorospe · 2019 · Wiley Interdisciplinary Reviews - RNA
- Targeting senescent cells with NKG2D-CAR T cellsYushuang Deng, Avadh Kumar, Kan Xie, Kristina Schaaf, Enzo Scifo, Sarah Morsy, Tao Li, Armin Ehninger, Daniele Bano, Dan Ehninger · 2024 · Cell Death Discovery
- Aging of the Retina: Molecular and Metabolic Turbulences and Potential InterventionsLaura Campello, Nivedita Singh, Jayshree Advani, Anupam K. Mondal, Ximena Corso‐Díaz, Anand Swaroop · 2021 · Annual Review of Vision Science
- Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brainKiss, Tamas, Nyúl-Tóth, Ádám, DelFavero, Jordan, Balasubramanian, Priya, Tarantini, Stefano, Faakye, Janet, Gulej, Rafal, Ahire, Chetan, Ungvari, Anna, Yabluchanskiy, Andriy et al. · 2022 · GeroScience
- The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosisZirun Jin, Yuzhuo Yang, Yalei Cao, Qi Wen, Yu Xi, Jianxing Cheng, Qiancheng Zhao, Jiaming Weng, Kai Hong, Hui Jiang et al. · 2023 · Microbiome
- Targeting aging and age-related diseases with vaccinesWu, Ruochen, Sun, Fei, Zhang, Weiqi, Ren, Jie, Liu, Guang-Hui · 2024 · Nature Aging
- Senescence as an Amyloid Cascade: The Amyloid Senescence HypothesisChaska C. Walton, David V Begelman, Wynnie Nguyen, Julie Kay Andersen · 2020 · Frontiers in Cellular Neuroscience
- Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosisPrathibha Reddy Gajjala, Rajesh K. Kasam, Divyalakshmi Soundararajan, Debora I. Sinner, Steven Kenneth Huang, Anil Goud Jegga, Satish Kumar Madala · 2021 · JCI Insight
- Senescence in chronic wounds and potential targeted therapiesXuerong Wei, Minxiong Li, Zijun Zheng, Jun Ma, Yanbin Gao, Lianglong Chen, Yujie Peng, Shengxiang Yu, Lei Yang · 2021 · Burns & Trauma
- Senescence and the Aging Immune System as Major Drivers of Chronic Kidney DiseaseSchroth, Johannes, Thiemermann, Christoph, Henson, Siân M. · 2020 · Frontiers in Cell and Developmental Biology
- cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysisLiqin Wang, Haojie Jin, Fleur Jochems, Siying Wang, Cor Lieftink, Isabel Mora Martinez, Giulia De Conti, Finn Edwards, Rodrigo Leite de Oliveira, Arnout G. Schepers et al. · 2022 · Nature Cancer
- Senescent-like microglia limit remyelination through the senescence associated secretory phenotypeGross, Phillip S., Durán-Laforet, Violeta, Ho, Lana T., Melchor, George S., Zia, Sameera, Manavi, Zeeba, Barclay, William E., Lee, Sung Hyun, Shults, Nataliia, Selva, Sean et al. · 2025 · Nature Communications
- Senolytic targets and new strategies for clearing senescent cellsMing‐Xia Ge, Li Hu, Hong-Shun Ao, Meiting Zi, Qing‐Peng Kong, Yonghan He · 2021 · Mechanisms of Ageing and Development
- Targeting pancreatic β cells for diabetes treatmentChirag Jain, Md Ansarullah, Sara Bilekova, Heiko Lickert · 2022 · Nature Metabolism
- Cellular senescence in ionizing radiation (Review)Zhengting Chen, Ke Cao, Yaoxiong Xia, Yunfen Li, Yu Hou, Li Wang, Lan Li, Li Chang, Wenhui Li · 2019 · Oncology Reports
- The Emerging Role of Senescence in Ocular DiseaseParameswaran Gangadharan Sreekumar, David R. Hinton, Ram Kannan · 2020 · Oxidative Medicine and Cellular Longevity
- Cellular Senescence and Senotherapies in the Kidney: Current Evidence and Future DirectionsMarie Helena Docherty, David Baird, Jeremy Hughes, David A. Ferenbach · 2020 · Frontiers in Pharmacology
- Senescence in the Development and Response to Cancer with Immunotherapy: A Double-Edged SwordAnthony M. Battram, Mireia Bachiller, Beatriz Martín-Antonio · 2020 · International Journal of Molecular Sciences
- Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cellsYi-Deun Jung, Seul-Ki Park, Dayeon Kang, Supyong Hwang, Myoung-Hee Kang, Seungwoo Hong, Jai-Hee Moon, Jae-Sik Shin, Dong‐Hoon Jin, Dalsan You et al. · 2020 · Redox Biology
- Transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell statesLauren D. Walter, Jessica L. Orton, Ioannis Ntekas, Ern Hwei Hannah Fong, Viviana I. Maymí, Brian D. Rudd, Iwijn De Vlaminck, Jennifer H. Elisseeff, Benjamin D. Cosgrove · 2024 · Nature Aging