Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 385

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Chlorhexidine stabilizes the adhesive interface: A 2-year in vitro study

Open access
Breschi, Lorenzo, Mazzoni, Annalisa, Nato, Fernando, Carrilho, Marcela, Visintini, Erika, Tjäderhane, Leo, Ruggeri, Alessandra, Tay, Franklin R., Dorigo, Elettra De Stefano, Pashley, David H.·2010·Dental Materials

Abstract

Objectives This study evaluated the role of endogenous dentin MMPs in auto-degradation of collagen fibrils within adhesive-bonded interfaces. The null hypotheses tested were that adhesive blends or chlorhexidine digluconate (CHX) application does not modify dentin MMPs activity and that CHX used as therapeutic primer does not improve the stability of adhesive interfaces over time. Methods Zymograms of protein extracts from human dentin powder incubated with Adper Scotchbond 1XT (SB1XT) on untreated or 0.2–2% CHX treated dentin were obtained to assay dentin MMPs activity. Microtensile bond strength and interfacial nanoleakage expression of SB1XT bonded interfaces (with or without CHX pre-treatment for 30s on the etched surface) were analyzed immediately and after 2 yr of storage in artificial saliva at 37°C. Results Zymograms showed that application of SB1XT to human dentin powder increases MMP-2 activity, while CHX pre-treatment inhibited all dentin gelatinolytic activity, irrespective from the tested concentration. CHX significantly lowered the loss of bond strength and nanoleakage seen in acid-etched resin-bonded dentin artificially aged for 2 yr. Significance The study demonstrates the active role of SB1XT in dentin MMP-2 activation and the efficacy of CHX inhibition of MMPs even if used at low concentration (0.2%).

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.dental.2009.11.153

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 26 references

Cited by

See all 385

Metadata

Authors
Breschi, L., Mazzoni, A., Nato, F., Carrilho, M., Visintini, E., Tjäderhane, L., Ruggeri, A., Tay, F. R., Dorigo, E. D. S., & Pashley, D. H.
Venue
Dental Materials
Publisher
Elsevier BV
Published
2010-04
Volume
26
Issue
4
Pages
320-325
ISSN
0109-5641 (ISSN-L)
OpenAlex
W2065356947
Cited by
385
References
26
FWCI
44.21
Type
journal article
Language
en
Open access
green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Chlorhexidine stabilizes the adhesive interface: A 2-year in vitro study. https://app.cochat.ai/papers/10.1016/j.dental.2009.11.153
The paper
Breschi, L., Mazzoni, A., Nato, F., Carrilho, M., Visintini, E., Tjäderhane, L., Ruggeri, A., Tay, F. R., Dorigo, E. D. S., & Pashley, D. H. (2010). Chlorhexidine stabilizes the adhesive interface: A 2-year in vitro study. Dental Materials. https://doi.org/10.1016/j.dental.2009.11.153

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.