A “community-friendly” version of integrated group therapy for patients with bipolar disorder and substance dependence: A randomized controlled trial
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Background Integrated group therapy, a new treatment for patients with bipolar disorder and substance use disorder, has previously been found to be efficacious in reducing substance use, but its length (20 sessions) and need for highly trained therapists may limit its adoption in substance use disorder community treatment programs. This paper compares a briefer (12 session) version of integrated group therapy, led by substance use disorder counselors without previous cognitive-behavioral training or bipolar disorder experience, to group drug counseling.Methods Sixty-one patients with bipolar disorder and substance dependence, taking mood stabilizers, were randomized to 12 sessions of integrated group therapy (n=31) or group drug counseling (n=30).Results Analyses of primary outcomes showed trends favoring integrated group therapy, with greater reduction in substance use during follow-up and a greater decline in risk of mood episodes during treatment. Secondary analyses favored integrated group therapy, with a significantly greater likelihood of achieving total abstinence, a significantly shorter time to the first abstinent month, and a significantly greater likelihood of achieving a "good clinical outcome" (a composite measure encompassing both substance use and mood simultaneously).Conclusions A shortened version of integrated group therapy can be delivered successfully by substance use disorder counselors, with better overall outcomes than those achieved with group drug counseling.
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From The substance use disorder treatment gap among US college students: Findings from the 2021 National Survey on Drug Use and Health (2024) · cites this paper as Weiss et al., 2009
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- Authors
- Weiss, R. D., Griffin, M. L., Jaffee, W. B., Bender, R. E., Graff, F. S., Gallop, R. J., & Fitzmaurice, G. M.
- Affiliations
- Harvard University (US)
- McLean Hospital (US)
- West Chester University (US)
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2009-10
- Volume
- 104
- Issue
- 3
- Pages
- 212-219
- ISSN
- 0376-8716 (ISSN-L)
- PMC
- PMC2735139
- OpenAlex
- W2085202814
- Cited by
- 106
- References
- 41
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 6 · 2022: 2 · 2021: 5 · 2020: 3 · 2019: 6 · 2018: 8 · 2017: 10 · 2016: 7 · 2015: 11 · 2014: 9 · 2013: 9 · 2012: 11
- FWCI
- 4.74
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (R01 DA15968, K24DA022288, R01DA015968)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Keywords
- bipolar disorder, substance dependence, substance use disorders, brief psychotherapy, community-based treatment, substance use abstinence, mood stabilizers
- MeSH terms
- Assessment of Medication Adherence, Adult, Antidepressive Agents, Bipolar Disorder, Community Mental Health Services, Counseling, Female, Humans, Male, Psychotherapy, Group, Time Factors, Cognitive Behavioral Therapy, Drug Monitoring, Diagnosis, Dual (Psychiatry), Antimanic Agents, Substance-Related Disorders, Medication Adherence
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