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Cited by 86

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes

Chu, Uyen B., Mavlyutov, Timur A., Chu, Ming-Liang, Yang, Huan, Schulman, Amanda, Mesangeau, Christophe, McCurdy, Christopher R., Guo, Lian-Wang, Ruoho, Arnold E.·2015·EBioMedicine
DOI 10.1016/j.ebiom.2015.10.017PMC PMC4740303
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Crossref · 10.1016/j.ebiom.2015.10.017

Cites

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  • Subsequent studies using cancer cells with stable knockdown or overexpression of PGRMC1 challenged the conclusion of an association because neither condition changed [3H]DTG binding.

    “Subsequent studies using cancer cells having a stable knockdown or overexpression of PGRMC1 challenged these conclusions since neither condition resulted in a change in binding of the σ2R radioligand, [3H]DTG17,18.”

    From Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex (2018) · cites this paper as [18]

  • Later studies by two independent groups found that S2R binding activity was not altered irrespective of the level of PGRMC1 expressed, and full activity persisted even in the absence of PGRMC1.

    “In later studies by two independent groups, however, in which PGRMC1 levels were genetically manipulated through overexpression or depletion, S2R binding activity was not altered irrespective of the level of PGRMC1 expressed, as assessed using the canonical S2R ligand tritiated di-o-tolylguanidine binding in the presence of saturating (+)-pentazocine, in a human epithelial cell line or a mouse mot”

    From Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases (2023) · cites this paper as [56]

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Citations

Cites

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Research works printed but not linked: 33

  1. Abate, 2015, Elements in support of the 'non-identity' of the PGRMC1 protein with the sigma2 receptor, Eur. J. Pharmacol., 758, 16, 10.1016/j.ejphar.2015.03.067 · DOI · Paper page
  2. Bali, 2013, Progesterone antagonism of neurite outgrowth depends on microglial activation via Pgrmc1/S2R, Endocrinology, 154, 2468, 10.1210/en.2012-2109 · DOI
  3. Bowen, 1989, Evidence for a multi-site model of the rat brain sigma receptor, Eur. J. Pharmacol., 163, 309, 10.1016/0014-2999(89)90200-8 · DOI
  4. Cassano, 2006, The sigma-2 receptor agonist PB28 inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells, Cell Calcium, 40, 23, 10.1016/j.ceca.2006.03.004 · DOI
  5. Colabufo, 2006, Is the sigma2 receptor a histone binding protein?, J. Med. Chem., 49, 4153, 10.1021/jm0600592 · DOI
  6. Cong, 2013, Multiplex genome engineering using CRISPR/Cas systems, Science, 339, 819, 10.1126/science.1231143 · DOI · Paper page
  7. Crawford, 2002, Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines, Cancer Res., 62, 313
  8. Fontanilla, 2008, Probing the steroid binding domain-like I (SBDLI) of the sigma-1 receptor binding site using N-substituted photoaffinity labels, Biochemistry, 47, 7205, 10.1021/bi800564j · DOI
  9. Gebreselassie, 2004, Sigma-2 receptors are specifically localized to lipid rafts in rat liver membranes, Eur. J. Pharmacol., 493, 19, 10.1016/j.ejphar.2004.04.005 · DOI
  10. Guo, 2012, Development of benzophenone-alkyne bifunctional sigma receptor ligands, Chembiochem, 13, 2277, 10.1002/cbic.201200427 · DOI
  11. Hanner, 1996, Purification, molecular cloning, and expression of the mammalian sigma1-binding site, Proc. Natl. Acad. Sci. U. S. A., 93, 8072, 10.1073/pnas.93.15.8072 · DOI
  12. Hellewell, 1990, A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain, Brain Res., 527, 244, 10.1016/0006-8993(90)91143-5 · DOI · Paper page
  13. Hellewell, 1994, Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling, Eur. J. Pharmacol., 268, 9, 10.1016/0922-4106(94)90115-5 · DOI · Paper page
  14. Hornick, 2010, The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine, Mol. Cancer, 9, 298, 10.1186/1476-4598-9-298 · DOI
  15. Itzhak, 1987, [3H]PCP-3-OH and (+)[3H]SKF 10047 binding sites in rat brain membranes: evidence of multiplicity, Eur. J. Pharmacol., 136, 231, 10.1016/0014-2999(87)90715-1 · DOI
  16. Itzhak, 1990, Clorgyline displays high affinity for sigma binding sites in C57BL/6 mouse brain, Eur. J. Pharmacol., 176, 107, 10.1016/0014-2999(90)90139-W · DOI
  17. Izzo, 2014, Alzheimer's therapeutics targeting amyloid beta 1–42 oligomers II: sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity, PLoS One, 9
  18. Kashiwagi, 2009, Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma, J. Transl. Med., 7, 24, 10.1186/1479-5876-7-24 · DOI
  19. Matsumoto, 2014, Sigma (sigma) receptors as potential therapeutic targets to mitigate psychostimulant effects, Adv. Pharmacol., 69, 323, 10.1016/B978-0-12-420118-7.00009-3 · DOI
  20. Mir, 2013, Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy, Autophagy, 9, 1566, 10.4161/auto.25889 · DOI · Paper page
  21. Morris, 1991, Interaction of forskolin with the P-glycoprotein multidrug transporter, Biochemistry, 30, 8371, 10.1021/bi00098a014 · DOI
  22. Nicholson, 2015, Characterization of CM572, a selective irreversible partial agonist of the Sigma-2 receptor with antitumor activity, J. Pharmacol. Exp. Ther., 10.1124/jpet.115.224105 · DOI
  23. Pal, 2007, Identification of regions of the sigma-1 receptor ligand binding site using a novel photoprobe, Mol. Pharmacol., 72, 921, 10.1124/mol.107.038307 · DOI
  24. Peluso, 2008, Endocrinology, 149, 534, 10.1210/en.2007-1050 · DOI
  25. Quirion, 1992, A proposal for the classification of sigma binding sites, Trends Pharmacol. Sci., 13, 85, 10.1016/0165-6147(92)90030-A · DOI
  26. Sanjana, 2014, Improved vectors and genome-wide libraries for CRISPR screening, Nat. Methods, 11, 783, 10.1038/nmeth.3047 · DOI · Paper page
  27. Vilner, 1993, Sigma receptor-active neuroleptics are cytotoxic to C6 glioma Cells in culture, Eur. J. Pharmacol., 244, 199, 10.1016/0922-4106(93)90029-9 · DOI
  28. Vilner, 2000, Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells, J. Pharmacol. Exp. Ther., 292, 900, 10.1016/S0022-3565(24)35369-8 · DOI · Paper page
  29. Vilner, 1995, Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines, Cancer Res., 55, 408
  30. Weber, 1986, 1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs, Proc. Natl. Acad. Sci. U. S. A., 83, 8784, 10.1073/pnas.83.22.8784 · DOI
  31. Wheeler, 2000, Sigma-2 receptors as a biomarker of proliferation in solid tumours, Br. J. Cancer, 82, 1223, 10.1054/bjoc.1999.1067 · DOI · Paper page
  32. Xu, 2011, Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site, Nat. Commun., 2, 380, 10.1038/ncomms1386 · DOI · Paper page
  33. Zufferey, 1998, Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery, J. Virol., 72, 9873, 10.1128/JVI.72.12.9873-9880.1998 · DOI · Paper page

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Metadata

Authors
Chu, U. B., Mavlyutov, T. A., Chu, M.-L., Yang, H., Schulman, A., Mesangeau, C., McCurdy, C. R., Guo, L.-W., & Ruoho, A. E.
Venue
EBioMedicine
Publisher
Elsevier BV
Published
2015-11
Volume
2
Issue
11
Pages
1806-1813
ISSN
2352-3964
DOI
10.1016/j.ebiom.2015.10.017
PMC
PMC4740303
Cited by
86
References
3
Language
en
Licence

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