The DOI matches its Crossref record; 167 of the 172 references it cites were found in a registry or an index, and 1 are not checked yet.
The central corticotropin releasing factor system during development and adulthood
Open accessAbstract
Corticotropin releasing factor (CRH) has been shown to contribute critically to molecular and neuroendocrine responses to stress during both adulthood and development. This peptide and its receptors are expressed in the hypothalamus, as well as in limbic brain areas including amygdala and hippocampus. This is consistent with roles for CRH in mediating the influence of stress on emotional behavior and cognitive function. The expression of CRH and of its receptors in hypothalamus, amygdala and hippocampus is age-dependent, and is modulated by stress throughout life (including the first postnatal weeks). Uniquely during development, the cardinal influence of maternal care on the central stress response governs the levels of central CRH expression, and may alter the 'set-point' of CRH-gene sensitivity to stress in a lasting manner.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The CEA is rich in stress hormones and their receptors,98, 99, 100, 101 and contributes to processing of stress signals.102, 103, 104”
From Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress (2014) · cites this paper as [100]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Handbook of Chemical Neuroanatomy
Stern, C. D. (1986) · Neurochemistry International · doi:10.1016/0197-0186(86)90021-5 · Cited by 4,160
Vale, W., Spiess, J., Rivier, C., & Rivier, J. (1981) · Science · doi:10.1126/science.6267699 · Cited by 3,965
Vale, W., Spiess, J., RIVIER, C. L., & Rivier, J. (1982) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-198205000-00013 · Cited by 3,904
Liu, D., Diorio, J., Tannenbaum, B., Caldji, C., Francis, D., Freedman, A., Sharma, S., Pearson, D., Plotsky, P. M., & Meaney, M. J. (1997) · Science · doi:10.1126/science.277.5332.1659 · Cited by 3,170
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
Gonzalez, G. A., & Montminy, M. (1989) · Cell · doi:10.1016/0092-8674(89)90013-5 · Cited by 2,464
Neurocircuitry of stress: central control of the hypothalamo–pituitary–adrenocortical axis
Herman, J. P., & Cullinan, W. E. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)10069-2 · Cited by 2,270
Swanson, L. W., Sawchenko, P. E., Rivier, J., & Vale, W. W. (2008) · Neuroendocrinology · doi:10.1159/000123454 · Cited by 1,953
Plotsky, P. M., & Meaney, M. J. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90189-v · Cited by 1,638 · cited 9×
“, 1998) or induced experimentally by handling (Plotsky and Meaney, 1993) has been shown to lower CRH expression in the hypothalamic paraventricular nucleus, reduce hormonal responses to stress, and increase hippocampal glucocorticoid receptor levels (Avishai-Eliner et al.”
BackgroundInfluentialVaughan, J. M., Donaldson, C. J., Bittencourt, J. C., Perrin, M. H., Lewis, K., Sutton, S. W., Chan, R. K. W., Turnbull, A. V., Lovejoy, D. A., RIVIER, C. L., et al. (1995) · Nature · doi:10.1038/378287a0 · Cited by 1,479
Caldji, C., Tannenbaum, B., Sharma, S., Francis, D., Plotsky, P. M., & Meaney, M. J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.9.5335 · Cited by 1,437
Flagged first, then by citations
4 of the 172 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 101–101 of 101
Demaestri, C., Delevich, K. M., Gourley, S. L., & Tseng, K. Y. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.107038
Metadata
- Authors
- Korosi, A., & Baram, T. Z.
- Affiliations
- University of California, Irvine (US)
- Corresponding author
- Baram, Tallie Z.
- ORCID
- Baram, Tallie Z.
- Venue
- European Journal of Pharmacology
- Publisher
- Elsevier BV
- Published
- 2008-04
- Volume
- 583
- Issue
- 2-3
- Pages
- 204-214
- ISSN
- 0014-2999 (ISSN-L)
- PMC
- PMC2329668
- OpenAlex
- W2031394080
- Cited by
- 102
- References
- 172
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 2 · 2022: 4 · 2021: 3 · 2020: 9 · 2019: 3 · 2018: 6 · 2017: 5 · 2016: 6 · 2015: 5 · 2014: 6 · 2013: 8 · 2012: 7
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- European Journal of Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Funders
- National Institutes of Health
- National Institute of Mental Health (MH73136, R01MH073136)
- National Institute of Neurological Disorders and Stroke (NS 28912, R01NS028912, R01NS039307)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- corticotropin-releasing factor, CRH receptors, hypothalamus, amygdala, hippocampus, stress response, neuroendocrine stress response, developmental programming, maternal care, age-related gene expression, emotional behavior, cognitive function
- MeSH terms
- Adult, Age Factors, Animals, Brain, Corticotropin-Releasing Hormone, Humans, Rodentia, Stress, Physiological, Gene Expression, Receptors, Corticotropin-Releasing Hormone
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
