The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Neuropeptides from concept to online database www.neuropeptides.nl
Abstract
In the early 1970's the term "neuropeptide" was used for the first time by David de Wied for peptides related to peptide hormones but with non-endocrine biological activity in the brain. This early notion appreciated neuropeptides as a specific class of chemical signals produced by neurons, released in a regulated fashion and acting on other neural cells. As we define them today, neuropeptides are encoded by over 70 genes in mammalian genomes. Neuropeptides can be clustered in at least 10 subfamilies according to structural features, for which often shared or related receptors exist. A complete overview is provided through hyperlinks to bioinformatic databases on genome and transcripts, protein structure and brain expression. Other proteineous signaling molecules in the nervous system which originally were discovered in other biological systems, particularly chemokines, growth factors and peptide hormones, share the hallmarks of classical neuropeptides and may be considered as neuropeptides as well.
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“For the purposes of the present work, we have relied therefore on the reasonably exhaustive list of 96 classical and candidate human and mouse NPP genes put forth in a widely cited publication (Burbach, 2010) and related website (http://neuropeptides.nl/, last accessed 10 October 2019).”
From Single-cell transcriptomic evidence for dense intracortical neuropeptide networks (2019) · cites this paper as Burbach, 2010
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Cites
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Peltonen, I. (2012) · Työväentutkimus Vuosikirja
Akhtar, M. N. (2015) · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
Wong, B. C. (2015) · TSpace (University of Toronto)
The Genetic Basis of Human Cognition: Intelligence, Learning and Memory
Avgan, N. (2018) · Queensland University of Technology · doi:10.5204/thesis.eprints.122903
A molecular characterization of inflammation in the bicipital tunnel
Campbell, A. L., Taylor, S. A., O’Dea, E. M., Shorey, M. E., Warren, R. F., & O’Brien, S. J. (2020) · Translational Sports Medicine · doi:10.1002/tsm2.224
The Nervous System and the Affective Neural Systems
Nogueira-Vale, E. (2024) · Springer eBooks · doi:10.1007/978-3-031-59038-2_3
Crosstalk between gut-brain axis and brain components along with associated neurological disorders
Bindal, P., Kaushal, S., Singh, C., & Singh, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-21680-0.00005-5
A comprehensive review on neuropeptides: databases and computational tools
Xu, W. H., Wang, L., Wang, M., Jiang, J., Xue, Z., & Wang, Y. (2025) · Computational Biomedicine · doi:10.70401/cbm.2025.0001
Takács, S., Skrapits, K., Göcz, B., Rumpler, É., Sárvári, M., Póliska, S., Rácz, G., Matolcsy, A., & Hrabovszky, E. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.19.671088
Anxiety-Like Behaviors and Neuropeptide Y, Tachykinins, and Beyond
Salluzzo, M., & Carboni, L. (2025) · Springer eBooks · doi:10.1007/978-3-031-73368-0_122
Tai, K. Y., KokSheik, W., Aghakhanian, F. F., Parhar, I. S., Dhaliwal, J., & Ayub, Q. (2020) · Figshare · doi:10.6084/m9.figshare.11986401
Tai, K. Y., KokSheik, W., Aghakhanian, F. F., Parhar, I. S., Dhaliwal, J., & Ayub, Q. (2020) · Figshare · doi:10.6084/m9.figshare.11986407
Tai, K. Y., KokSheik, W., Aghakhanian, F. F., Parhar, I. S., Dhaliwal, J., & Ayub, Q. (2020) · Figshare · doi:10.6084/m9.figshare.11986419
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Tai, K. Y., KokSheik, W., Aghakhanian, F. F., Parhar, I. S., Dhaliwal, J., & Ayub, Q. (2020) · Figshare · doi:10.6084/m9.figshare.11986380
Tai, K. Y., KokSheik, W., Aghakhanian, F. F., Parhar, I. S., Dhaliwal, J., & Ayub, Q. (2020) · Figshare · doi:10.6084/m9.figshare.11986413
Tai, K. Y., KokSheik, W., Aghakhanian, F. F., Parhar, I. S., Dhaliwal, J., & Ayub, Q. (2020) · Figshare · doi:10.6084/m9.figshare.11986350
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Coexistence of Peptides with Classical Neurotransmitters
Merighi, A. (2026) · Oxford University Press eBooks · doi:10.1093/9780197851494.003.0594
Takács, S., Skrapits, K., Göcz, B., Rumpler, É., Sárvári, M., Göblyös, B., Biri, D., Póliska, S., Rácz, G., Matolcsy, A., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-76688-w
Neuropeptides and Their Role in Brain Function
Gupta, S., Sharma, R., & Singh, S. (2026) · Royal Society of Chemistry eBooks · doi:10.1039/9781837071395-00082
Metadata
- Authors
- Burbach, J. P. H.
- Affiliations
- University Medical Center Utrecht (NL)
- Corresponding author
- Burbach, J. Peter H.
- ORCID
- Burbach, J. Peter H.
- Venue
- European Journal of Pharmacology
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 626
- Issue
- 1
- Pages
- 27-48
- ISSN
- 0014-2999 (ISSN-L)
- OpenAlex
- W2140412940
- Cited by
- 123
- References
- 31
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 7 · 2023: 9 · 2022: 13 · 2021: 7 · 2020: 14 · 2019: 7 · 2018: 10 · 2017: 2 · 2016: 7 · 2015: 6 · 2014: 5 · 2013: 4 · 2012: 5
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
- Keywords
- neuropeptides, neuropeptide genes, neuropeptide receptors, neuropeptide signaling, chemokines, growth factors, peptide hormones, brain expression
- MeSH terms
- Animals, Gene Expression Regulation, Humans, Neurons, Neuropeptides, Terminology as Topic, Internet, Databases, Protein
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