The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Neuropeptides from concept to online database www.neuropeptides.nl
Abstract
In the early 1970's the term "neuropeptide" was used for the first time by David de Wied for peptides related to peptide hormones but with non-endocrine biological activity in the brain. This early notion appreciated neuropeptides as a specific class of chemical signals produced by neurons, released in a regulated fashion and acting on other neural cells. As we define them today, neuropeptides are encoded by over 70 genes in mammalian genomes. Neuropeptides can be clustered in at least 10 subfamilies according to structural features, for which often shared or related receptors exist. A complete overview is provided through hyperlinks to bioinformatic databases on genome and transcripts, protein structure and brain expression. Other proteineous signaling molecules in the nervous system which originally were discovered in other biological systems, particularly chemokines, growth factors and peptide hormones, share the hallmarks of classical neuropeptides and may be considered as neuropeptides as well.
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“For the purposes of the present work, we have relied therefore on the reasonably exhaustive list of 96 classical and candidate human and mouse NPP genes put forth in a widely cited publication (Burbach, 2010) and related website (http://neuropeptides.nl/, last accessed 10 October 2019).”
From Single-cell transcriptomic evidence for dense intracortical neuropeptide networks (2019) · cites this paper as Burbach, 2010
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Cites
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Hughes, J., Smith, T. W., Kosterlitz, H. W., Fothergill, L. A., Morgan, B. A., & Morris, H. R. (1975) · Nature · doi:10.1038/258577a0 · Cited by 3,806
Amara, S. G., Jonas, V., Rosenfeld, M. G., Ong, E. S., & Evans, R. M. (1982) · Nature · doi:10.1038/298240a0 · Cited by 2,105
Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor
Nakanishi, S., Inoue, A., Kita, T., Inoue, A., Nakamura, M., Chang, A. C. Y., Cohen, S. N., & Numa, S. (1979) · Nature · doi:10.1038/278423a0 · Cited by 1,760
Hökfelt, T. G. M., Johansson, O., Ljungdahl, Å., Lundberg, J. M., & Schultzberg, M. (1980) · Nature · doi:10.1038/284515a0 · Cited by 1,552
Frontiers in Neuroendocrinology, 1969.
(1970) · Annals of Internal Medicine · doi:10.7326/0003-4819-72-1-153_3 · Cited by 1,119
Common precursor to corticotropins and endorphins
Mains, R. E., Eipper, B. A., & LING, N. C. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.7.3014 · Cited by 1,106
ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTRand Sortilin
Teng, H. K., Teng, K. K., Lee, R., Wright, S., Tevar, S., Almeida, R. D., Kermani, P., Torkin, R., Chen, Z.-Y., Lee, F. S., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5123-04.2005 · Cited by 1,013
Synthesis, transport, and release of posterior pituitary hormones
Brownstein, M. J., Russell, J. T., & Gainer, H. (1980) · Science · doi:10.1126/science.6153132 · Cited by 838
Tatemoto, K., & Mutt, V. (1980) · Nature · doi:10.1038/285417a0 · Cited by 663
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing
Nawa, H., Kotani, H., & Nakanishi, S. (1984) · Nature · doi:10.1038/312729a0 · Cited by 572
Long Term Effect of Vasopressin on the Maintenance of a Conditioned Avoidance Response in Rats
de Wied, D. (1971) · Nature · doi:10.1038/232058a0 · Cited by 468
Yang, J., Siao, C.-J., Nagappan, G., Marinic, T., Jing, D., McGrath, K., Chen, Z.-Y., Mark, W., Tessarollo, L., Lee, F. S., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2244 · Cited by 449
On the Physiological Action of Extracts of Pituitary Body and certain other Glandular Organs
Oliver, G. D., & Schäfer, E. A. (1895) · The Journal of Physiology · doi:10.1113/jphysiol.1895.sp000565 · Cited by 371
The expression and function of chemokines involved in CNS inflammation
Ubogu, E. E., Cossoy, M. B., & Ransohoff, R. M. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.11.002 · Cited by 281
du Vigneaud, V., Lawler, H. C., & Popenoe, E. A. (1953) · Journal of the American Chemical Society · doi:10.1021/ja01115a554 · Cited by 272
A Major Metabolite of Arginine Vasopressin in the Brain Is a Highly Potent Neuropeptide
Burbach, J. P. H., Kovács, G. L., de Wied, D., Nispen, J. W. V., & Greven, H. M. (1983) · Science · doi:10.1126/science.6351252 · Cited by 262
Self-citationde Wied, D., & Bohus, B. (1966) · Nature · doi:10.1038/2121484a0 · Cited by 254
LING, N. C., Burgus, R. C., & Guillemin, R. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.11.3942 · Cited by 219
Greven, H. M., & de Wied, D. (1973) · Progress in brain research · doi:10.1016/s0079-6123(08)64098-4 · Cited by 162
Inhibitory and Facilitatory Effect of Two Related Peptides on Extinction of Avoidance Behavior
Bohus, B., & de Wied, D. (1966) · Science · doi:10.1126/science.153.3733.318 · Cited by 157
Selective conversion of β-endorphin into peptides related to γ- and α-endorphin
Burbach, J. P. H., Loeber, J. G., Verhoef, J., Wiegant, V. M., de Kloet, E. R., & de Wied, D. (1980) · Nature · doi:10.1038/283096a0 · Cited by 130
Self-citationPeptidergic neurons: Facts and trends
Scharrer, B. (1978) · General and Comparative Endocrinology · doi:10.1016/0016-6480(78)90243-5 · Cited by 126
Salio, C., Averill, S., Priestley, J. V., & Merighi, A. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20358 · Cited by 89
Lande, S., Witter, A., & de Wied, D. (1971) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)77188-9 · Cited by 78
Central Actions of Neurohypophysial Hormones
de Wied, D. (1983) · Progress in brain research · doi:10.1016/s0079-6123(08)64383-6 · Cited by 75
Chapter 9 The neuropeptide concept
de Wied, D. (1987) · Progress in brain research · doi:10.1016/s0079-6123(08)60199-5 · Cited by 48
Wade, N. (1981) · Cited by 27
Biochemistry of vasopressin fragments
Burbach, J. P. H., Schoots, O., & Hernando, F. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)61566-6 · Cited by 15
Self-citationPeptides other than the neurotrophins that can be cleaved from proneurotrophins: A neglected story
Dicou, E. (2007) · Archives of Physiology and Biochemistry · doi:10.1080/13813450701531250 · Cited by 13
Studies of the Distribution of Biologically Active Peptides in the Brain
Brownstein, M. (1977) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-8849-8_3 · Cited by 4
VASOPRESSIN IN AFFECTIVE ILLNESS
de Wied, D. (1978) · The Lancet · doi:10.1016/s0140-6736(78)91794-4 · Cited by 4
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Neuropeptides and the Microbiota-Gut-Brain Axis
Holzer, P., & Farzi, A. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-0897-4_9 · Cited by 451
A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH
Fenselau, H., Campbell, J. N., Verstegen, A. M. J., Madara, J. C., Xu, J., Shah, B. P., Resch, J. M., Yang, Z., Mandelblat-Cerf, Y., Livneh, Y., et al. (2017) · Nature Neuroscience · doi:10.1038/nn.4442 · Cited by 233
Hypothalamic neuropeptides and the regulation of appetite
Parker, J., & Bloom, S. R. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.02.004 · Cited by 242
NeuroPep: a comprehensive resource of neuropeptides
Wang, Y., Wang, M., Yin, S., Jang, R., Wang, J., Xue, Z., & Xu, T. (2015) · Database · doi:10.1093/database/bav038 · Cited by 163
Single-cell transcriptomic evidence for dense intracortical neuropeptide networks
Smith, S. J., Sümbül, U., Graybuck, L. T., Collman, F., Seshamani, S., Gala, R., Gliko, O., Elabbady, L., Miller, J. A., Bakken, T. E., et al. (2019) · eLife · doi:10.7554/elife.47889 · Cited by 156
Metadata
- Authors
- Burbach, J. P. H.
- Affiliations
- University Medical Center Utrecht (NL)
- Corresponding author
- Burbach, J. Peter H.
- ORCID
- Burbach, J. Peter H.
- Venue
- European Journal of Pharmacology
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 626
- Issue
- 1
- Pages
- 27-48
- ISSN
- 0014-2999 (ISSN-L)
- OpenAlex
- W2140412940
- Cited by
- 123
- References
- 31
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 7 · 2023: 9 · 2022: 13 · 2021: 7 · 2020: 14 · 2019: 7 · 2018: 10 · 2017: 2 · 2016: 7 · 2015: 6 · 2014: 5 · 2013: 4 · 2012: 5
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
- Keywords
- neuropeptides, neuropeptide genes, neuropeptide receptors, neuropeptide signaling, chemokines, growth factors, peptide hormones, brain expression
- MeSH terms
- Animals, Gene Expression Regulation, Humans, Neurons, Neuropeptides, Terminology as Topic, Internet, Databases, Protein
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