Cited by 123Neuropeptides and Animal PhysiologyNeuroendocrine regulation and behaviorChemical Synthesis and Analysis

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Neuropeptides from concept to online database www.neuropeptides.nl

Burbach, J. Peter H.·2010·European Journal of Pharmacology

DOI 10.1016/j.ejphar.2009.10.015

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Abstract

In the early 1970's the term "neuropeptide" was used for the first time by David de Wied for peptides related to peptide hormones but with non-endocrine biological activity in the brain. This early notion appreciated neuropeptides as a specific class of chemical signals produced by neurons, released in a regulated fashion and acting on other neural cells. As we define them today, neuropeptides are encoded by over 70 genes in mammalian genomes. Neuropeptides can be clustered in at least 10 subfamilies according to structural features, for which often shared or related receptors exist. A complete overview is provided through hyperlinks to bioinformatic databases on genome and transcripts, protein structure and brain expression. Other proteineous signaling molecules in the nervous system which originally were discovered in other biological systems, particularly chemokines, growth factors and peptide hormones, share the hallmarks of classical neuropeptides and may be considered as neuropeptides as well.

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Identification of two related pentapeptides from the brain with potent opiate agonist activity
Hughes, J., Smith, T. W., Kosterlitz, H. W., Fothergill, L. A., Morgan, B. A., & Morris, H. R. (1975) · Nature · doi:10.1038/258577a0 · Cited by 3,806
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products
Amara, S. G., Jonas, V., Rosenfeld, M. G., Ong, E. S., & Evans, R. M. (1982) · Nature · doi:10.1038/298240a0 · Cited by 2,105
Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor
Nakanishi, S., Inoue, A., Kita, T., Inoue, A., Nakamura, M., Chang, A. C. Y., Cohen, S. N., & Numa, S. (1979) · Nature · doi:10.1038/278423a0 · Cited by 1,760
Peptidergic neurones
Hökfelt, T. G. M., Johansson, O., Ljungdahl, Å., Lundberg, J. M., & Schultzberg, M. (1980) · Nature · doi:10.1038/284515a0 · Cited by 1,552
Frontiers in Neuroendocrinology, 1969.
(1970) · Annals of Internal Medicine · doi:10.7326/0003-4819-72-1-153_3 · Cited by 1,119
Common precursor to corticotropins and endorphins
Mains, R. E., Eipper, B. A., & LING, N. C. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.7.3014 · Cited by 1,106
ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTRand Sortilin
Teng, H. K., Teng, K. K., Lee, R., Wright, S., Tevar, S., Almeida, R. D., Kermani, P., Torkin, R., Chen, Z.-Y., Lee, F. S., et al. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.5123-04.2005 · Cited by 1,013
Synthesis, transport, and release of posterior pituitary hormones
Brownstein, M. J., Russell, J. T., & Gainer, H. (1980) · Science · doi:10.1126/science.6153132 · Cited by 838
Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides
Tatemoto, K., & Mutt, V. (1980) · Nature · doi:10.1038/285417a0 · Cited by 663
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing
Nawa, H., Kotani, H., & Nakanishi, S. (1984) · Nature · doi:10.1038/312729a0 · Cited by 572

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Authors: Burbach, J. P. H.
Affiliations: University Medical Center Utrecht (NL)
Corresponding author: Burbach, J. Peter H.
ORCID: Burbach, J. Peter H.
Venue: European Journal of Pharmacology
Publisher: Elsevier BV
Published: 2010-01
Volume: 626
Issue: 1
Pages: 27-48
ISSN: 0014-2999 (ISSN-L)
DOI: 10.1016/j.ejphar.2009.10.015
OpenAlex: W2140412940
Cited by: 123
References: 31
Citations by year: 2026: 7 · 2025: 12 · 2024: 7 · 2023: 9 · 2022: 13 · 2021: 7 · 2020: 14 · 2019: 7 · 2018: 10 · 2017: 2 · 2016: 7 · 2015: 6 · 2014: 5 · 2013: 4 · 2012: 5
FWCI: 0.37
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: European Journal of Pharmacology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Physical Sciences › Chemistry › Organic Chemistry › Chemical Synthesis and Analysis
Keywords: neuropeptides, neuropeptide genes, neuropeptide receptors, neuropeptide signaling, chemokines, growth factors, peptide hormones, brain expression
MeSH terms: Animals, Gene Expression Regulation, Humans, Neurons, Neuropeptides, Terminology as Topic, Internet, Databases, Protein

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