Cited by 75Toxic Organic Pollutants ImpactSperm and Testicular FunctionEffects and risks of endocrine disrupting chemicals

Investigation of polycyclic aromatic hydrocarbon level in blood and semen quality for residents in Pearl River Delta Region in China

Song, Xiao Fei, Chen, Zhi Yuan, Zang, Zhi Jun, Zhang, Ya Nan, Zeng, Feng, Peng, Yen Ping, Yang, Chen·2013·Environment International

Abstract

This study is the first one investigating the correlation between the concentration of polycyclic aromatic hydrocarbon (PAHs) in blood and semen qualities for residents in the Pearl River Delta (PRD) region in China. Blood samples from 53 infertile volunteers were studied for measures of semen quality and 16 PAHs. Information on the study subjects' living habits (such as smoking, drinking and preference of consumption for food) and general information (age, body-mass-index (BMI) and educational background) were also collected. Statistical results showed that age and BMI were significantly and negatively related to semen motilities. The total concentrations of PAHs (∑16 PAHs) in the blood were 12,010, 7493, 9105 and 8647ng/g for factory workers, office workers, technicians and salespersons, respectively. In addition, ∑16 PAHs in the blood of smokers, drinkers and heavy-taste food consumers were 11,950, 11,266 and 12,141ng/g, which were higher than those observed in nonsmokers (10,457ng/g), nondrinkers (10,920ng/g) and light-taste food consumers (9202ng/g), individually. Furthermore, the Pearson correlation analysis results showed significant positive correlations between BMI and ∑16 PAHs in the blood. Statistically significant correlations were observed between semen motilities and ∑16 PAHs in the blood as well. Logistic regression results showed that for each 1ng/g increase in ∑16 PAHs in blood samples, the log odds of experiencing a pregnancy decrease by 0.039 on average. However, more evidences are needed to clarify the impact of PAHs in the blood to male infertility.

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Crossref · 10.1016/j.envint.2013.08.003

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  • PAHs and their metabolites can be found in the blood of adults, children and neonates, as well as in urine and maternal milk.

    “Advances in bioanalytical methods have now revealed that PAHs and their metabolites can be found in the blood of adults,24, 25, 26, 27 children28, 29 and neonates,26, 30 as well as in urine18, 31, 32, 33 and maternal milk.26”

    From The impact of airborne pollution on skin (2019) · cites this paper as [25]

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Authors
Song, X. F., Chen, Z. Y., Zang, Z. J., Zhang, Y. N., Zeng, F., Peng, Y. P., & Yang, C.
Affiliations
  • South China University of Technology (CN)
  • Third Affiliated Hospital of Sun Yat-sen University (CN)
  • Sun Yat-sen University (CN)
  • Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution Control (CN)
Corresponding author
  • Zeng, Feng
  • Peng, Yen Ping
Venue
Environment International
Publisher
Elsevier BV
Published
2013-10
Volume
60
Pages
97-105
ISSN
0160-4120 (ISSN-L)
OpenAlex
W2094942573
Cited by
75
References
53
Citations by year
2025: 2 · 2024: 8 · 2023: 7 · 2022: 16 · 2021: 8 · 2020: 5 · 2019: 5 · 2018: 4 · 2017: 7 · 2016: 5 · 2015: 6 · 2014: 2
FWCI
3.18
Type
journal article
Language
en
Open access
closed
Locations
  • Environment International (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • 2011 Education Department breeding project of Guangdong, China (LYM11011)
  • National Science Foundation, China (41173104, 21077138)
  • fund of Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution Control
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
Keywords
polycyclic aromatic hydrocarbons, semen quality, male infertility, sperm motility, body mass index, smoking, alcohol consumption, dietary habits, occupational exposure, Pearl River Delta
MeSH terms
Adult, Age Factors, Alcohol Drinking, China, Educational Status, Environmental Monitoring, Female, Humans, Infertility, Male, Male, Occupations, Polycyclic Aromatic Hydrocarbons, Pregnancy, Semen, Smoking, Sperm Motility, Body Mass Index, Logistic Models, Rivers, Semen Analysis, Young Adult

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