Towards a fuller assessment of benefits to children's health of reducing air pollution and mitigating climate change due to fossil fuel combustion
Abstract
Background Fossil fuel combustion by-products, including particulate matter (PM 2.5), polycyclic aromatic hydrocarbons (PAH), nitrogen dioxide (NO 2) and carbon dioxide (CO 2), are a significant threat to children's health and equality. Various policies to reduce emissions have been implemented to reduce air pollution and mitigate climate change, with sizeable estimated health and economic benefits. However, only a few adverse outcomes in children have been considered, resulting in an undercounting of the benefits to this vulnerable population.Objectives Our goal was to expand the suite of child health outcomes addressed by programs to assess health and economic benefits, such as the Environmental Protection Agency (EPA) Benefits Mapping and Analysis Program (BenMAP), by identifying concentration-response (C-R) functions for six outcomes related to PM 2.5, NO 2, PAH, and/or PM 10: preterm birth (PTB), low birthweight (LBW), autism, attention deficit hyperactivity disorder, IQ reduction, and the development of childhood asthma.Methods We conducted a systematic review of the literature published between January 1, 2000 and April 30, 2018 to identify relevant peer-reviewed case-control and cohort studies and meta-analyses. In some cases meta-analyses were available that provided reliable C-R functions and we assessed their consistency with subsequent studies. Otherwise, we reviewed all eligible studies published between our search dates.Results For each pollutant and health outcome, we present the characteristics of each selected study. We distinguish between C-R functions for endpoints having a causal or likely relationship (PTB, LBW, autism, asthma development) with the pollutants for incorporation into primary analyses and endpoints having a suggestive causal relationship with the pollutants (IQ reduction, ADHD) for secondary analyses.Conclusion We have identified C-R functions for a number of adverse health outcomes in children associated with air pollutants largely from fossil fuel combustion. Their incorporation into expanded assessments of health benefits of clean air and climate mitigation policies will provide an important incentive for preventive action.
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Increased in-utero exposure to particular matter and other air pollutants could have physical, cognitive, and behavioural effects on the child later on in life.
“There are also some indications that increased in-utero exposure to particular matter and other air pollutants could have physical, cognitive, and behavioural effects on the child later on in life.86”
From Climate change and child health: A scoping review and an expanded conceptual framework (2021) · cites this paper as [86]
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“Another systematic literature review found compelling evidence that exposure to PM 2.5 , PM with an aerodynamic diameter of ≤ 10 mm (PM 10 ), and NO 2 contributes to the risk of asthma development in childhood (88).”
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“Exposure to PM during pregnancy has also been associated with adverse to birth outcomes, such as preterm births and low birthweights [7].”
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Polycyclic aromatic compounds (PACs) in the Canadian environment: Ambient air and deposition
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“…the direct impacts of climate change on human development can have lifetime consequences, as when, for example, childhood exposure to climate-fueled air pollution increases the likelihood of respiratory disease, differential brain development, and mental illness (Perera et al., 2019).”
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“Cancer and neurodevelopmental effects of gestational air pollution are also documented in human studies [9, 62].”
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“Eighty % of air pollutants are produced by coal combustion, oil, gasoline, and diesel fuel, which are used primarily for electricity generation, transport, heat, and industry [7].”
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“Children are more vulnerable to the health effects of emissions because of their physiology, growth, and higher respiratory rates (Perera et al., 2019). f. National defence The impact of dependence on fuel oil on national security is related to the cost of imports, the cost of military operations…”
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“, 2014), adverse birth outcomes (Stieb et al., 2012; Perera et al., 2019), childhood asthma (Khreis et al.”
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“One of the main contributors to air pollution event is the burning of fossil fuels (e.g., coal, petrol, and diesel), which produces numerous airborne toxic emissions, particularly pollutants like particulate matters (e.g., PM 10 and PM 2.5 ) (Perera et al. 2019; Shindell and Smith 2019).”
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“Furthermore, the effect of greenhouse gases and subsequently the threat of global warming due to the combustion of massive petro-fuels is one of the most important motivations to search for alternate fuels (Perera et al. 2019; Pandey et al. 2022).”
- Authors
- Perera, F., Ashrafi, A., Kinney, P., & Mills, D.
- Affiliations
- Columbia University (US)
- Boston University (US)
- Schulman, Ronca & Bucuvalas (US)
- Corresponding author
- Perera, F.
- Venue
- Environmental Research
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 172
- Pages
- 55-72
- ISSN
- 0013-9351 (ISSN-L)
- OpenAlex
- W2905351498
- Cited by
- 163
- References
- 112
- Citations by year
- 2026: 7 · 2025: 22 · 2024: 24 · 2023: 30 · 2022: 30 · 2021: 22 · 2020: 21 · 2019: 7
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Environmental Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Environmental Health Sciences (2P50ES09600)
- Foundation for the National Institutes of Health (UG3OD023290-02)
- Blanchette Hooker Rockefeller Fund
- John Merck Fund
- U.S. Environmental Protection Agency (RD83615401)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
- Social Sciences › Sociology and Political Science › Environmental Justice and Health Disparities
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
- Keywords
- air pollution, fossil fuel combustion, child health, concentration-response functions, particulate matter, nitrogen dioxide, polycyclic aromatic hydrocarbons, PM10, preterm birth, low birth weight, autism spectrum disorder, attention deficit hyperactivity disorder, childhood asthma, BenMAP, climate change mitigation, air quality policy, health equity
- MeSH terms
- Child Health, Air Pollution, Environmental Exposure, Female, Fossil Fuels, Humans, Pregnancy, Risk Assessment, Climate Change
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