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Cited by 316Cancer survivorship and careMental Health Treatment and AccessAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

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Anxiety and depression in adult cancer patients: ESMO Clinical Practice Guideline

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Grassi, L., Caruso, R., Riba, M.B., Lloyd-Williams, M., Kissane, D., Rodin, G., McFarland, D., Campos-Ródenas, R., Zachariae, R., Santini, D., Ripamonti, C.I.·2023·ESMO Open
DOI 10.1016/j.esmoop.2023.101155PMC PMC10163167
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Abstract

•Anxiety and depressive disorders are common in patients with cancer.•A higher prevalence seen in patients with cancer than the general population is often underrecognised.•Psychotherapy, cognitive behavioural therapy and mindfulness-based therapies are effective treatments.•Psychopharmacological treatments have been shown to be effective treatments of anxiety and depressive disorders.

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Figure 1 Screening and management of anxiety symptoms/disorders. Purple: general categories or stratification; white: other aspects of management; turquoise: systemic therapy. AD, antidepressant; CBT, cognitive behavioural therapy; GAD, generalised anxiety disorder; MBT, mindfulness-based therapy; SNRI, serotonin and norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor. aAt diagnosis, treatment, conclusion of treatment, recurrence and when relevant. bAnxious mood (feeling tense, worried), rumination about recurrence is disabling, sleep disturbance, agitation, difficulty in concentration. cAs appropriate.
Figure 1 Screening and management of anxiety symptoms/disorders. Purple: general categories or stratification; white: other aspects of management; turquoise: systemic therapy. AD, antidepressant; CBT, cognitive behavioural therapy; GAD, generalised anxiety disorder; MBT, mindfulness-based therapy; SNRI, serotonin and norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor. aAt diagnosis, treatment, conclusion of treatment, recurrence and when relevant. bAnxious mood (feeling tense, worried), rumination about recurrence is disabling, sleep disturbance, agitation, difficulty in concentration. cAs appropriate.CC BY-NC-ND · PubMed Central
Figure 2 Screening and management of depressive symptoms. Purple: general categories or stratification; white: other aspects of management; turquoise: systemic therapy. ACT, acceptance and commitment therapy; AD, antidepressant; BDI-II, Beck Depression Inventory, second edition; CALM, Managing Cancer and Living Meaningfully; CBSR, cognitive behavioural stress reduction; CBT, cognitive behavioural therapy; MBT, mindfulness-based therapy; PHQ-9, Patient Health Questionnaire-9; SNRI, serotonin and norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor. aAt diagnosis, treatment, conclusion of treatment, recurrence and when relevant. bDepressed mood (feeling down, depressed, helpless/hopeless); anhedonia (little interest or pleasure in doing things). cAs appropriate.
Figure 2 Screening and management of depressive symptoms. Purple: general categories or stratification; white: other aspects of management; turquoise: systemic therapy. ACT, acceptance and commitment therapy; AD, antidepressant; BDI-II, Beck Depression Inventory, second edition; CALM, Managing Cancer and Living Meaningfully; CBSR, cognitive behavioural stress reduction; CBT, cognitive behavioural therapy; MBT, mindfulness-based therapy; PHQ-9, Patient Health Questionnaire-9; SNRI, serotonin and norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor. aAt diagnosis, treatment, conclusion of treatment, recurrence and when relevant. bDepressed mood (feeling down, depressed, helpless/hopeless); anhedonia (little interest or pleasure in doing things). cAs appropriate.CC BY-NC-ND · PubMed Central

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Metadata

Authors
Grassi, L., Caruso, R., Riba, M. B., Lloyd-Williams, M., Kissane, D., Rodin, G., McFarland, D., Campos-Ródenas, R., Zachariae, R., Santini, D., & Ripamonti, C. I.
Affiliations
  • University of Ferrara (IT)
  • University of Michigan (US)
  • Monash Medical Centre (AU)
  • Princess Margaret Cancer Centre (CA)
  • University of Rochester Medicine (US)
  • Aarhus University (DK)
  • Sapienza University of Rome (IT)
  • Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
ORCID
Venue
ESMO Open
Publisher
Elsevier BV
Published
2023-04
Volume
8
Issue
2
Pages
101155
ISSN
2059-7029 (ISSN-L)
DOI
10.1016/j.esmoop.2023.101155
PMC
PMC10163167
OpenAlex
W4324143593
Cited by
316
References
125
Citations by year
2026: 128 · 2025: 106 · 2024: 76 · 2023: 6
FWCI
38.54
Type
journal article
Language
en
Open access
Licence
Locations
  • ESMO Open (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion, other-oa)
  • Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, cc-by-nc-nd)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, cc-by-nc-nd)
  • Liverpool John Moores University (submittedVersion)
  • Zaguan (Universidad de Zaragoza) (submittedVersion, cc-by-nc-nd)
  • Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, other-oa)
Funders
European Society for Medical Oncology
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
anxiety, depression, cancer patients, psycho-oncology, cognitive behavioral therapy, mindfulness-based interventions, psychopharmacological treatment, prevalence of mental disorders
MeSH terms
Adult, Anxiety, Depression, Humans, Neoplasms

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