Essential oil composition and antioxidant and antimicrobial properties of the aerial parts of Salvia eremophila Boiss. from Iran
Abstract
The essential oil composition and in vitro antioxidant and antimicrobial activity of the essential oil and methanol extract of Salvia eremophila were evaluated in this research. GC and GC/MS analysis of the plant essential oil resulted in the identification of 28 compounds representing 99.24% of the oil. Borneol (21.83%), alpha-pinene (18.80%), bornyl acetate (18.68%) and camphene (6.54%) were detected as the major components consisting 65.85% of the oil. The plant essential oil and methanol extract were also subjected to screenings for the evaluation of their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and beta-carotene-linoleic acid tests. While the plant essential oil showed only weak antioxidant activities, its methanol extract was considerably active in both DPPH (IC(50)=35.19 microg/ml) and beta-carotene-linoleic acid (inhibition percentage: 72.42%) tests. Appreciable total phenolic content (101.25 microg/mg) was also detected for the plant methanol extract as gallic acid equivalent in the Folin-Ciocalteu test. The plant was also screened for its antimicrobial activity and good to moderate inhibitions were recorded for its essential oil and methanol extract against most of the tested microorganisms.
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Salvia eremophila essential oil had an inhibition percentage about one third of BHT, while methanolic extracts of the same plant had activities comparable to BHT.
“The percentage inhibition of Salvia eremophila Boiss. oil was of about one third of that of BHT, in contrast to the methanolic extracts of the same plant, which presented activities comparable to that of BHT.”
From Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review (2010) · cites this paper as [48]
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“Among the wide variety of plants and their constituents, those with a long history of consumption in food and medicine via traditional medicine possess great importance for analytical and biological studies [1,2].”
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Khaleel, S., Jaran, A., & Haddadin, M. S. Y. (2016) · Journal of Advances in Medicine and Medical Research · doi:10.9734/bjmmr/2016/24935 · Cited by 33 · see citing works
“Natural products, particularly those present in medicinal plants, have gained more interest as food ingredients because of their safety, accessibility, and positive impact on health [5].”
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“[34] was performed (with a few modifications) to determine the DPPH free-radical–scavenging activity.”
MethodThe mutagenic, antimutagenic and antioxidant properties of Hypericum lydium
Boran, R., & Uğur, A. (2016) · Pharmaceutical Biology · doi:10.1080/13880209.2016.1242146 · Cited by 22 · see citing works
“DPPH radical scavenging activity The free radical-scavenging activity of the ethanol extract of H. lydium was determined using the stable DPPH according to Ebrahimabadi et al. (2010) with a little modification.”
MethodUlukanlı, Z., Karabörklü, S., Öztürk, B., Çenet, M., & Balcılar, M. (2012) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.12035 · Cited by 22 · see citing works
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Components, Antioxidant and Antibacterial Activity of Tomato Seed Oil
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“Finding natural plant materials with both antioxidation and antibacterial effects becomes an ideal goal in the research field of food additives research (Ebrahimabadi et al., 2010).”
BackgroundChemical Compositions and Biological Activities of Essential Oils of Beilschmiedia glabra
Salleh, W. M. N. H. W., Ahmad, F., Yen, K. H., & Zulkifli, R. M. (2015) · Natural Product Communications · doi:10.1177/1934578x1501000740 · Cited by 20 · see citing works
“The βcarotene/linoleic acid test is usually used for the estimation of the antioxidant potential ability to delay lipid peroxidation by reacting with the chain propagating peroxyl radicals faster than the reaction of these radicals with proteins or fatty acid side chains [11].”
MethodKsouri, A., Dob, T., Belkebir, A., Dahmane, D., & Nouasri, A. (2017) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v16i1.7 · Cited by 19 · see citing works
“The minimum inhibitory concentration (MIC) determination of the plant material was carried out by agar dilution method [13].”
MethodAlemu, B., Molla, M. D., Endale, H. T., Dekebo, A., & Dejenie, T. A. (2024) · Scientific Reports · doi:10.1038/s41598-024-56659-1 · Cited by 20 · see citing works
Karamian, R., Asadbegy, M., & Pakazad, R. (2014) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2014.895156 · Cited by 18 · see citing works
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“The minimum inhibitory concentration (MIC) was determined by the agar dilution method as described by Ebrahimabadi et al. (2010).”
MethodAntifungal Plants of Iran: An Insight into Ecology, Chemistry, and Molecular Biology
Razzaghi‐Abyaneh, M., Shams‐Ghahfarokhi, M., & Rai, M. (2013) · Springer eBooks · doi:10.1007/978-3-642-38076-1_2 · Cited by 13 · see citing works
“Methanolic extract of plant aerial parts was shown to effectively inhibit the growth of Candida albicans, while the plant essential oil did not affect fungal growth even at a concentration of 1,000 lg/ml (Ebrahimabadi et al. 2010a).”
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“The colour changes from deep violet to yellow within 30 min (Ebrahimabadi et al. 2010).”
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“This value is comparable to the MICs of the commercial antibacterial agents rifampin and gentamicin against S. epidermidis [8], which are 0.25 and 0.5 mg/mL, respectively.”
InfluentialIn vitro Bioactivity of Essential Oils and Methanol Extracts of Salvia reuterana from Iran
Safaei‐Ghomi, J., Masoomi, R., Kashi, F. J., & Batooli, H. (2012) · Natural Product Communications · doi:10.1177/1934578x1200700527 · Cited by 11 · see citing works
“Contrary to the earlier report that β-caryophyllene, linalool, linalyl acetate, viridiflorol, manool, α-humulene, borneol, α-pinene, 1,8-cineole, camphor, α-bisabolol, bornyl acetate, α-thujone, (E)-β-ocimene and α-gurjunene were predominately present in the oil, we did not find these compounds in the present study [9…”
ResultEvaluation of Antioxidant , Antimicrobial and Cytotoxicity of Alcea Kurdica Alef
Qader, S. W., & Awad, H. M. (2014) · Jordan Journal of Biological Sciences · doi:10.12816/0008240 · Cited by 11 · see citing works
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“The EO of S. eremophila was almost inactive in DPPH and acting weakly in BCB test (Ebrahimabadi et al ., 2010).”
Boran, R., Uğur, A., & Saraç, N. (2018) · Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi · doi:10.19113/sdufenbed.471994 · Cited by 11 · see citing works
Preparation of phytoncide-emitting nylon/PP sheath/core fiber and the release profile of phytoncide
Lee, J. Y., Oh, S. J., Lee, M. S., Park, J. Y., Ryu, J. J., & Lee, K. H. (2012) · Fibers and Polymers · doi:10.1007/s12221-012-1209-2 · Cited by 10 · see citing works
Review on extraction methods, antioxidant and antimicrobial properties of volatile oils
Fahim, M., Shrivastava, B., Shrivastava, A. K., Ibrahim, M. M., Parveen, R., & Ahmad, S. (2017) · Annals of Phytomedicine An International Journal · doi:10.21276/ap.2017.6.2.2 · Cited by 9 · see citing works
Safaei‐Ghomi, J., Masoomi, R., Kashi, F. J., & Batooli, H. (2016) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2016.1195292 · Cited by 9 · see citing works
Nouasri, A., Dob, T., Toumi, M., Dahmane, D., Krimat, S., Lamari, L., & Chelgoume, C. (2015) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2014.981591 · Cited by 8 · see citing works
A new approach for prevention the oxidations and mutations: zinc borate
Uğur, A., Ceylan, Ö., Boran, R., Ayrıkçil, S., Saraç, N., & Yilmaz, D. (2019) · Journal of Boron · doi:10.30728/boron.573718 · Cited by 8 · see citing works
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“Several studies have reported that phenolic compounds mediate the antimicrobial activities of various plant extracts (6,14, 29).”
BackgroundKrimat, S., Dob, T., Toumi, M., Lamari, L., & Dahmane, D. (2015) · Journal of Essential Oil Research · doi:10.1080/10412905.2015.1025921 · Cited by 8 · see citing works
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“In recent years, numerous studies have been conducted on antimicrobial activities of essential oils (Sarikurkcu et al. 2010, Eryiğit et al. 2013, Meng et al. 2016, Ebrahimabadi et al. 2010).”
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Sarhadi, E., Ebrahimi, S. N., Hadjiakhoondi, A., & Manayi, A. (2021) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2021.1921622 · Cited by 6 · see citing works
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Khalid, K. A., El-Sayed, A., El-Gohary, A. E., El-Garf, I. A., & Sabry, R. M. (2021) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2022.2026255 · Cited by 5 · see citing works
Rather, G. A., Nanda, A., Raj, E., Mathivanan, N., Thiruvengadam, K., Sofi, M. A., & Nayak, B. K. (2023) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2023.00193 · Cited by 7 · see citing works
IN VITRO - IN VIVO CORRELATION OF THE ANTIOXIDANT CAPACITY OF SALVIAE AETHEROLEUM ESSENTIAL OIL
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“It has antibacterial [16], antioxidant [17], anti-inflammatory [18], antitumor and antidiabetic [19], hepatoprotective [14], immune protection [20], antihepatitis [21], and disinfectant [13] properties.”
BackgroundIn vitro antibacterial and antioxidant activity of Rosmarinus officinalis
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Comparison of Essential Oil Components of Salvia forskahlei L. Collected from Nature and Cultivated
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- Authors
- Ebrahimabadi, A. H., Mazoochi, A., Kashi, F. J., Djafari-Bidgoli, Z., & Batooli, H.
- Affiliations
- University of Kashan (IR)
- Corresponding author
- Ebrahimabadi, Abdolrasoul H.
- Venue
- Food and Chemical Toxicology
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 48
- Issue
- 5
- Pages
- 1371-1376
- ISSN
- 0278-6915 (ISSN-L)
- OpenAlex
- W1974210773
- Cited by
- 120
- References
- 58
- Citations by year
- 2025: 3 · 2024: 6 · 2023: 4 · 2022: 4 · 2021: 8 · 2020: 8 · 2019: 5 · 2018: 10 · 2017: 10 · 2016: 9 · 2015: 15 · 2014: 12 · 2013: 6 · 2012: 8
- FWCI
- 12.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food and Chemical Toxicology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
- Keywords
- essential oil composition, borneol, α-pinene, bornyl acetate, camphene, methanol extract, antioxidant activity, antimicrobial activity, total phenolic content, DPPH radical scavenging, β-carotene/linoleic acid assay, medicinal plants
- MeSH terms
- Anti-Infective Agents, Antioxidants, Bacteria, Fungi, Iran, Gas Chromatography-Mass Spectrometry, Microbial Sensitivity Tests, Oils, Volatile, Phenols, Plant Oils, Salvia, Plant Components, Aerial, In Vitro Techniques
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