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Solution Structure of the Ras Binding Domain of the Protein Kinase Byr2 from Schizosaccharomyces pombe

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Observation of slow dynamic exchange processes in RAS protein crystals by 31P solid state NMR spectroscopy

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Indirect Referencing of ³¹P and ¹⁹F NMR Spectra

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Ras Conformational Ensembles, Allostery, and Signaling

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Small-molecule modulation of Ras signaling

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Conformational states of human rat sarcoma (RAS) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis

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Structural Basis for Conformational Dynamics of GTP-bound Ras Protein

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Recent advances in biosensory and medicinal therapeutic applications of zinc(II) and copper(II) coordination complexes

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Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes

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Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

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Direct Modulation of Small GTPase Activity and Function

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Metal–Bis(2‐picolyl)amine Complexes as State 1(T) Inhibitors of Activated Ras Protein

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Solid state NMR: new tools for insight into enzyme function

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Lessons from computer simulations of Ras proteins in solution and in membrane

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A novel mechanism for the modulation of the Ras-effector interaction by small molecules

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Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal

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Improved Binding of Raf to Ras·GDP Is Correlated with Biological Activity

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Exceptionally high-affinity Ras binders that remodel its effector domain

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Delineating the RAS Conformational Landscape

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E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form

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Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics

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How Anionic Lipids Affect Spatiotemporal Properties of KRAS4B on Model Membranes.

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Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography

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Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR

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Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells

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High Pressure NMR Methods for Characterizing Functional Substates of Proteins

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Elucidating the Mode of Action of a Typical Ras State 1(T) Inhibitor

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Conformations and binding pockets of HRas and its guanine nucleotide exchange factors complexes in the guanosine triphosphate exchange process

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Cu2+-cyclen as Probe to Identify Conformational States in Guanine Nucleotide Binding Proteins

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State 1(T) Inhibitors of Activated Ras

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Identification of functional substates of KRas during GTP hydrolysis with enhanced sampling simulations

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Stabilisierung eines niederaffinen Zustands für Effektoren im menschlichen Ras‐Protein durch Cyclenkomplexe

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High pressure 31P NMR spectroscopy on guanine nucleotides

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NMR in integrated biophysical drug discovery for RAS: past, present, and future

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Critical Roles of Interactions among Switch I-preceding Residues and between Switch II and Its Neighboring α-Helix in Conformational Dynamics of the GTP-bound Ras Family Small GTPases

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Metall‐Bis(2‐picolyl)amin‐Komplexe als Zustand‐1(T)‐Inhibitoren für aktiviertes Ras‐Protein

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Conformational states of human H-Ras detected by high-field EPR, ENDOR, and31P NMR spectroscopy

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Interconversion of Two GDP-Bound Conformations and Their Selection in an Arf-Family Small G Protein

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Direkte Modulation von Aktivität und Funktion kleiner GTPasen

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Solid-State 31P NMR Spectroscopy of Precipitated Guanine Nucleotide-Binding Protein Ras in Complexes with Its Effector Molecules Raf Kinase and RalGDS

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Impact of KRAS-G12 Mutations on the KRAS-GTP Bound Conformational Dynamics: Structure, Free Energy Barriers and Drugging Pockets

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