The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction
Open accessAbstract
Simple sphingolipids such as ceramide and sphingomyelin (SM) as well as more complex glycosphingolipids play very important roles in cell function under physiological conditions and during disease development and progression. Sphingolipids are particularly abundant in the nervous system. Due to their amphiphilic nature they localize to cellular membranes and many of their roles in health and disease result from membrane reorganization and from lipid interaction with proteins within cellular membranes. In this review we discuss some of the functions of sphingolipids in processes that entail cellular membranes and their role in neurodegenerative diseases, with an emphasis on SM, ceramide and gangliosides.
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Cites
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Cited by
Linking lipids to Alzheimer's disease: cholesterol and beyond
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Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications
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Self-citationGangliosides: glycosphingolipids essential for normal neural development and function
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APP Function and Lipids: A Bidirectional Link
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Metadata
- Authors
- Posse de Chaves, E., & Sipione, S.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2009-12-16
- Volume
- 584
- Issue
- 9
- Pages
- 1748-1759
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W1989089334
- Cited by
- 274
- References
- 109
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Posse de Chaves, E., & Sipione, S. (2010). Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction. FEBS Letters. https://doi.org/10.1016/j.febslet.2009.12.010
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