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Soy protein isolates of varying isoflavone content do not adversely affect semen quality in healthy young men
Open accessAbstract
Objective To determine the effects of consumption of soy protein of varying isoflavone content on parameters of semen quality in healthy young men.Design Randomized crossover intervention.Setting University campus.Patient(s) Healthy adult men (age 27.5 ± 5.67 years, body mass index 25.4 ± 3.14 kg/m(2)).Intervention(s) Milk protein isolate (MPI), low-isoflavone soy protein isolate (low-iso SPI; 1.64 ± 0.19 mg isoflavones/day, expressed as aglycone equivalents), and high-isoflavone soy protein isolate (high-iso SPI; 61.7 ± 7.35 mg isoflavones/day, expressed as aglycone equivalents) for 57 days each separated by 28-day washout periods.Main outcome measure(s) Urinary isoflavones were measured from 24-hour urine samples collected on days 54-56 of each treatment period. Semen quality parameters (semen volume, sperm concentration, sperm count, sperm percent motility, total motile sperm count, sperm morphology) were measured from semen samples collected on days 1 and 57 of each treatment period.Result(s) Urinary isoflavones were significantly higher after consumption of high-iso SPI compared with the low-iso SPI and MPI. Semen parameters, including semen volume, sperm concentration, sperm count, sperm percent motility, total motile sperm count, and sperm morphology, were not significantly affected by consumption of either low- or high-iso SPI compared with MPI.Conclusion(s) Consumption of soy protein of low or high isoflavone content does not adversely affect semen quality in a sample of healthy adult men.
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Protein supplementation, regardless of isoflavone content, did not influence semen quality parameters in healthy young men.
“the protein supplementation, regardless of isoflavone content, did not influence semen quality parameters (semen volume, sperm concentration, sperm count, sperm mobility, sperm percent motility, total motile sperm count, or sperm morphology) in healthy young men [138].”
From Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function (2020) · cites this paper as [138]
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Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function
Hertzler, S. R., Lieblein-Boff, J. C., Weiler, M., & Allgeier, C. (2020) · Nutrients · doi:10.3390/nu12123704 · Cited by 594
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Metadata
- Authors
- Beaton, L. K., McVeigh, B. L., Dillingham, B. L., Lampe, J. W., & Duncan, A. M.
- Affiliations
- University of Guelph (CA)
- Fred Hutch Cancer Center (US)
- Corresponding author
- Duncan, Alison M.
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 94
- Issue
- 5
- Pages
- 1717-1722
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2060528866
- Cited by
- 49
- References
- 34
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 2 · 2023: 5 · 2022: 4 · 2021: 4 · 2020: 6 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 5 · 2015: 1 · 2014: 2 · 2013: 6
- FWCI
- 0.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Institute for Cancer Research
- University of Guelph
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Phytoestrogen effects and research
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
- Keywords
- soy protein isolate, isoflavones, semen quality, sperm motility, sperm morphology, milk protein isolate, male fertility
- MeSH terms
- Adult, Humans, Isoflavones, Male, Sperm Count, Sperm Motility, Spermatozoa, Time Factors, Cross-Over Studies, Soybean Proteins, Semen Analysis
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