Cited by 190Reproductive Health and TechnologiesStress Responses and CortisolReproductive Biology and Fertility

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Stress reduces conception probabilities across the fertile window: evidence in support of relaxation

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Buck Louis, Germaine M., Lum, Kirsten J., Sundaram, Rajeshwari, Chen, Zhen, Kim, Sungduk, Lynch, Courtney D., Schisterman, Enrique F., Pyper, Cecilia·2011·Fertility and Sterility

DOI 10.1016/j.fertnstert.2010.06.078PMC PMC2975045

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Abstract

Objective To assess salivary stress biomarkers (cortisol and α-amylase) and female fecundity. Design Prospective cohort design. Setting United Kingdom. Patient(s) 274 women aged 18 to 40 years who were attempting pregnancy. Intervention(s) Observation for six cycles or until pregnancy: women collected basal saliva samples on day 6 of each cycle, and used fertility monitors to identify ovulation and pregnancy test kits for pregnancy detection. Main outcome measure(s) Salivary cortisol (μg/dL) and α-amylase (U/mL) concentration measurements; fecundity measured by time-to-pregnancy and the probability of pregnancy during the fertile window as estimated from discrete-time survival and Bayesian modeling techniques, respectively. Result(s) Alpha-amylase but not cortisol concentrations were negatively associated with fecundity in the first cycle (fecundity odds ratio=0.85; 95% confidence interval 0.67, 1.09) after adjusting for the couples' ages, intercourse frequency, and alcohol consumption. Statistically significant reductions in the probability of conception across the fertile window during the first cycle attempting pregnancy were observed for women whose salivary concentrations of α-amylase were in the upper quartiles in comparison with women in the lower quartiles (highest posterior density: -0.284; 95% interval -0.540, -0.029). Conclusion(s) Stress significantly reduced the probability of conception each day during the fertile window, possibly exerting its effect through the sympathetic medullar pathway.

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Handbook of Physiology.
Plum, F. (1960) · Archives of Neurology · doi:10.1001/archneur.1960.03840090124020 · Cited by 10,388
Salivary cortisol in psychoneuroendocrine research: recent developments and applications
Kirschbaum, C., & Hellhammer, D. H. (1994) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)90013-2 · Cited by 2,107
Monte Carlo Estimation of Bayesian Credible and HPD Intervals
Chen, M.-H., & Shao, Q.-M. (1999) · Journal of Computational and Graphical Statistics · doi:10.1080/10618600.1999.10474802 · Cited by 1,251
Maternal Stress and Preterm Birth
Dole, N. (2003) · American Journal of Epidemiology · doi:10.1093/aje/kwf176 · Cited by 848
The preterm prediction study: maternal stress is associated with spontaneous preterm birth at less than thirty-five weeks gestation
Copper, R. L., Goldenberg, R. L., Das, A., Elder, N., Swain, M., Norman, G., Ramsey, R., Cotroneo, P., Collins, B. A., Johnson, F., et al. (1996) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(96)70042-x · Cited by 683
Determinants of the diurnal course of salivary alpha-amylase
Nater, U. M., Rohleder, N., Schlotz, W., Ehlert, U., & Kirschbaum, C. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.02.007 · Cited by 631 · cited 4×
“(33) observed 76 participants who contributed 857 a-amylase measurements during the course of the day and reported a marked diurnal profile that was unrelated to perceived stress.”
BackgroundInfluential
Human salivary alpha-amylase reactivity in a psychosocial stress paradigm
Nater, U. M., Rohleder, N., Gaab, J., Berger, S., Jud, A., Kirschbaum, C., & Ehlert, U. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2004.09.009 · Cited by 618
Changes with age in the level and duration of fertility in the menstrual cycle
Dunson, D. B. (2002) · Human Reproduction · doi:10.1093/humrep/17.5.1399 · Cited by 577
Salivary α‐Amylase in Biobehavioral Research: Recent Developments and Applications
GRANGER, D. A., KIVLIGHAN, K. T., El‐SHEIKH, M., GORDIS, E. B., & STROUD, L. R. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1384.008 · Cited by 572
Effect of psychological stress on the salivary cortisol and amylase levels in healthy young adults
Takai, N., Yamaguchi, M., Aragaki, T., Eto, K., Uchihashi, K., & Nishikawa, Y. (2004) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2004.06.007 · Cited by 568 · cited 1×
“Both cortisol and a-amylase have been demonstrated to be valid markers of perceived psychosocial stress (14, 15), and the lack of correlation between these markers is indicative of their separate pathways (16).”
Background

Flagged first, then by citations

Show all 35 references

Research works printed but not linked: 3

Knaus, 1929, Eine neue Methods zur Bestimmung des Ovulationstermines, Zentralbl F Gynak, 53, 2193
Ogino, 1930, Ovulationstermin und Konzeptionstermin, Zentralbl F Gynak, 54, 464
Moran, 1975, Adrenergic receptors, Vol. 6, 117

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Authors: Buck Louis, G. M., Lum, K. J., Sundaram, R., Chen, Z., Kim, S., Lynch, C. D., Schisterman, E. F., & Pyper, C.
Affiliations: National Institutes of Health (US)
The Ohio State University (US)
University of Oxford (GB)
ORCID: Sundaram, Rajeshwari
Chen, Zhen
Kim, Sungduk
Lynch, Courtney D.
Schisterman, Enrique F.
Venue: Fertility and Sterility
Publisher: Elsevier BV
Published: 2011-06
Volume: 95
Issue: 7
Pages: 2184-2189
ISSN: 0015-0282 (ISSN-L)
DOI: 10.1016/j.fertnstert.2010.06.078
PMC: PMC2975045
OpenAlex: W2001105792
Cited by: 189
References: 35
Citations by year: 2026: 5 · 2025: 11 · 2024: 9 · 2023: 8 · 2022: 14 · 2021: 14 · 2020: 17 · 2019: 11 · 2018: 17 · 2017: 15 · 2016: 11 · 2015: 10 · 2014: 17 · 2013: 11 · 2012: 14
FWCI: 11.81
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 4013 d)
Locations: Fertility and Sterility (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development
Topics: Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Keywords: stress, fecundity, salivary cortisol, salivary amylase, time to pregnancy, fertile window, ovulation, sympathetic nervous system, female fertility
MeSH terms: Adult, alpha-Amylases, Bayes Theorem, Female, Fertility, United Kingdom, Humans, Hydrocortisone, Infertility, Female, Ovarian Function Tests, Ovulation, Pregnancy, Pregnancy Tests, Prospective Studies, Risk Factors, Saliva, Stress, Psychological, Biomarkers, Chi-Square Distribution, Proportional Hazards Models, Odds Ratio, Risk Assessment, Pregnancy Rate, Young Adult

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Stress reduces conception probabilities across the fertile window: evidence in support of relaxation

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