Cited by 344Endometriosis Research and TreatmentUterine Myomas and TreatmentsGynecological conditions and treatments

The DOI matches its Crossref record; 98 of the 100 references it cites were found in a registry or an index.

Pathogenesis of uterine adenomyosis, invagination or metaplasia?

Open access

García-Solares, Javier, Donnez, Jacques, Donnez, Olivier, Dolmans, Marie-Madeleine·2018·Fertility and Sterility

DOI 10.1016/j.fertnstert.2017.12.030

Open this paper in CoChat — free account

Abstract

Adenomyosis is a commonly diagnosed estrogen-dependent gynecological disorder that causes pelvic pain, abnormal uterine bleeding, and infertility. Despite its prevalence and severity of symptoms, its pathogenesis and etiology have not yet been elucidated. The aim of this manuscript is to review the different hypotheses on the origin of adenomyotic lesions and the mechanisms involved in the evolution and progression of the disease. Two main theories have been proposed to explain the origin of adenomyosis. The most common suggests involvement of tissue injury and the repair mechanism and claims that adenomyosis results from invagination of the endometrial basalis into the myometrium. An alternative theory maintains that adenomyotic lesions result from metaplasia of displaced embryonic pluripotent Müllerian remnants or differentiation of adult stem cells. Previous investigations performed in human adenomyotic lesions and corroborated by studies in mice supported the involvement of the epithelial-mesenchymal transition process in the early stages of progression and spread of adenomyosis. However, studies conducted in a recently developed baboon model indicate that collective cell migration may be implicated in the later events of invasion. This suggests that the invasiveness of this complex uterine disorder is not driven by a single mechanism of migration but by a time-dependent combination of two processes.

Integrity signals

Registry

Crossref · 10.1016/j.fertnstert.2017.12.030

Cites

98 of 98 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Polyak, K., & Weinberg, R. A. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2620 · Cited by 3,302
Collective cell migration in morphogenesis, regeneration and cancer
Friedl, P., & Gilmour, D. T. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2720 · Cited by 2,804
Linking DNA methylation and histone modification: patterns and paradigms
Cedar, H., & Bergman, Y. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2540 · Cited by 2,267
The snail superfamily of zinc-finger transcription factors
Nieto, M. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm757 · Cited by 1,719
Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.
Acloque, H., Adams, M. S., Fishwick, K., Bronner-Fraser, M., & Nieto, M. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38019 · Cited by 1,350
Peritoneal endometriosis, ovarian endometriosis, and adenomyotic nodules of the rectovaginal septum are three different entities
Nisolle, M., & Donnez, J. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00191-x · Cited by 1,279
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
Bolós, V., Peinado, H., Pérez‐Moreno, M., Fraga, M. F., Esteller, M., & Cano, A. (2002) · Journal of Cell Science · doi:10.1242/jcs.00224 · Cited by 1,100
Classifying collective cancer cell invasion
Friedl, P., Locker, J. D., Sahai, E. A., & Segall, J. E. (2012) · Nature Cell Biology · doi:10.1038/ncb2548 · Cited by 966
Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the Morphological Uterus Sonographic Assessment (MUSA) group
den Bosch, T. V., Dueholm, M., Leone, F. P., Valentin, L., Rasmussen, C. K., Votino, A., Schoubroeck, D. V., Landolfo, C., Installé, A., Guerriero, S., et al. (2015) · Ultrasound in Obstetrics and Gynecology · doi:10.1002/uog.14806 · Cited by 776
Epithelial–mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic
Voulgari, A., & Pintzas, A. (2009) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2009.03.002 · Cited by 683

Flagged first, then by citations

Show all 100 references

2 of the 100 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

Siegler, 1994, Adenomyosis, J Reprod Med, 39, 841

Sorted by citations

Items 101–200 of 344

Molecular Targets for Nonhormonal Treatment Based on a Multistep Process of Adenomyosis Development
Kobayashi, H. (2022) · Reproductive Sciences · doi:10.1007/s43032-022-01036-4 · Cited by 17
Anemia-Associated Platelets and Plasma Prothrombin Time Increase in Patients with Adenomyosis
Lin, Q., Li, T., Ding, S., Yu, Q., & Zhang, X. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11154382 · Cited by 17
The Role of Platelets in the Pathogenesis and Pathophysiology of Adenomyosis
Guo, S. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12030842 · Cited by 17
Concurrent Diagnosis of Adenomyosis and Congenital Uterine Anomalies: A Review
Feghali, E., Etrusco, A., Haydamous, J., Ayed, A., Laganà, A. S., Chiàntera, V., Vitale, S. G., Angioni, S. L., Stabile, G., & Sleiman, Z. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13050716 · Cited by 17
Advances in Adenomyosis Treatment: High-Intensity Focused Ultrasound, Percutaneous Microwave Therapy, and Radiofrequency Ablation
Athanasiou, A., Fruscalzo, A., Dedes, I., Mueller, M. D., Londero, A. P., Marti, C., Guani, B., & Féki, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13195828 · Cited by 18
Adenomyosis: Disease, uterine aging process leading to symptoms, or both?
Πρωτόπαπας, Α., Grimbizis, G., Athanasiou, S., & Loutradis, D. (2020) · PubMed Central · Cited by 17
Clinical Characteristics of Patients with Endometrial Cancer and Adenomyosis
Casadio, P., Raffone, A., Maletta, M., Travaglino, A., Raimondo, D., Raimondo, I., Santoro, A., Paradisi, R., Zannoni, G. F., Mollo, A., et al. (2021) · Cancers · doi:10.3390/cancers13194918 · Cited by 16
The effect of adenomyosis types on clinical outcomes of IVF embryo transfer after ultra-long GnRH agonist protocol
Han, B., Liang, T., Zhang, W., Ma, C., & Qiao, J. (2022) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.09.021 · Cited by 16
Are lower levels of apoptosis and autophagy behind adenomyotic lesion survival?
d'Argent, M., Stratopoulou, C. A., Cussac, S., Camboni, A., Jadoul, P., Donnez, J., & Dolmans, M. (2023) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2023.06.003 · Cited by 16
Anti-Inflammatory Activity of Sanjie Zhentong Capsule Assessed By Network Pharmacology Analysis of Adenomyosis Treatment
Du, L. Y., Du, D., Chen, B., Ding, Y., Zhang, T., & Xiao, W. L. (2020) · Drug Design Development and Therapy · doi:10.2147/dddt.s228721 · Cited by 16
Investigation of the role of platelets in the aetiopathogenesis of adenomyosis
Mosele, S., Stratopoulou, C. A., Camboni, A., Donnez, J., & Dolmans, M. (2021) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2021.01.009 · Cited by 16
Pregnancy outcomes of infertile women with ultrasound-diagnosed adenomyosis for in vitro fertilization and frozen–thawed embryo transfer
Zhang, X., Zhang, Y., Shi, R., Zhang, Y., Zhang, X.-L., Hu, X., Hu, X., & Hu, Y. (2021) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-021-06011-z · Cited by 16
The Impact of Adenomyosis on Pregnancy
Tsikouras, P. N., Kritsotaki, N., Nikolettos, K., Kotanidou, S., Oikonomou, E., Bothou, Α., Andreou, S., Nalmpanti, T., Chalkia, K., Spanakis, V., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12081925 · Cited by 15
The inconsistent pathogenesis of endometriosis and adenomyosis: insights from endometrial metabolome and microbiome
Li, C., Xu, X., Zhao, X., & Du, B. (2025) · mSystems · doi:10.1128/msystems.00202-25 · Cited by 15
Osteopontin Splicing Isoforms Contribute to Endometriotic Proliferation, Migration, and Epithelial-Mesenchymal Transition in Endometrial Epithelial Cells
Ho, N.-T., Lin, S.-W., Lee, Y.-R., Tzeng, C., & Kao, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315328 · Cited by 16
Increased NKG2A+CD8+ T-cell exhaustion in patients with adenomyosis
Liu, W., Sheng, S., Zhu, C., Li, C., Zou, Y., Yang, C., Chen, Z., Wang, F., & Jiao, X. (2023) · Mucosal Immunology · doi:10.1016/j.mucimm.2023.02.003 · Cited by 15
Mapping Human Uterine Disorders Through Single-Cell Transcriptomics
Boldu-Fernández, S., Lliberos, C., Simón, C., & Mas, A. (2025) · Cells · doi:10.3390/cells14030156 · Cited by 18
Elevated Circular RNA PVT1 Promotes Eutopic Endometrial Cell Proliferation and Invasion of Adenomyosis via miR‐145/Talin1 Axis
Wang, Y., Duan, H., Wang, S., Quan, Y., Huang, J., & Guo, Z. (2021) · BioMed Research International · doi:10.1155/2021/8868700 · Cited by 15
Attenuated monoamine oxidase a impairs endometrial receptivity in women with adenomyosis via downregulation of FOXO1
Tian, J., Zhang, C., Kang, N., Wang, J., Kong, N., Zhou, J., Wu, M., Ding, L., Sun, H., Yan, G., et al. (2021) · Biology of Reproduction · doi:10.1093/biolre/ioab182 · Cited by 15
Celecoxib, a selective COX‑2 inhibitor, markedly reduced the severity of tamoxifen‑induced adenomyosis in a murine model
Jin, Z., Wu, X., Liu, H., & Xu, C. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8580 · Cited by 15
Adjustment of progesterone administration after endometrial transcriptomic analysis does not improve reproductive outcomes in women with adenomyosis
Juárez-Barber, E., Cozzolino, M., Corachán, A., Alecsandru, D., Pellicer, N., Pellicer, A., & Ferrero, H. (2023) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.09.007 · Cited by 16
Overview of crosstalk between stromal and epithelial cells in the pathogenesis of adenomyosis and shared features with deep endometriotic nodules
Zipponi, M., Cacciottola, L., & Dolmans, M. (2024) · Human Reproduction · doi:10.1093/humrep/deae116 · Cited by 14
Adenomyosis-associated infertility: an update of the immunological perspective
Cao, Y., Yang, D., Cai, S., Yang, L., Yu, S., Geng, Q., Mo, M., Li, W., Wei, Y., Li, Y., et al. (2024) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2024.104703 · Cited by 20
Rapid reduction of adenomyosis coexisting with leiomyoma volume during treatment with Relugolix
Yamanaka, K., Washio, K., Uchida, A., Sasagawa, Y., Nishimoto, M., Yamasaki, Y., Nagamata, S., & Terai, Y. (2023) · Gynecological Endocrinology · doi:10.1080/09513590.2023.2237121 · Cited by 13
Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis
Qin, X., Sun, W., Wang, C., Li, M., Ζhao, X., Li, C., & Zhang, H. (2021) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-021-00800-6 · Cited by 13
Evolution of uterine adenomyosis volume during and after GnRH antagonist (linzagolix) treatment: lessons for further clinical trials
Donnez, J., Donnez, O., & Dolmans, M. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.07.012 · Cited by 14
A novel technique for myometrial defect closure after robot-assisted laparoscopic adenomyomectomy: A retrospective cohort study
Hijazi, A., Chung, Y., Sinan, N. A., Kang, H.-J., Ko, M., Lee, S., Song, J. Y., & Kim, M.-R. (2022) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2021.11.014 · Cited by 13
Genetic aspects of endometriosis and adenomyosis: a modern view on the problem
Adamyan, L. V., Kuznetsova, M. V., Pivazyan, L. G., Davydova, Y. D., & Trofimov, D. Y. (2023) · Russian Journal of Human Reproduction · doi:10.17116/repro20232904214 · Cited by 12
Levonorgestrel Ameliorates Adenomyosis via lncRNA H19/miR-17/TLR4 Pathway
Liang, N., Zhang, W., Wang, H.-J., Shi, W., Wang, L., & Ma, L. (2020) · Drug Design Development and Therapy · doi:10.2147/dddt.s248095 · Cited by 12
Establishment of a novel mouse model of adenomyosis suitable for longitudinal and quantitative analysis and perinatal outcome studies
Elsherbini, M., Koga, K., Hiraoka, T., Kumasawa, K., Maki, E., Satake, E., Taguchi, A., Makabe, T., Takeuchi, A., Izumi, G., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-22413-8 · Cited by 11
Endometrial stromal cell signaling and microRNA exosome content in women with adenomyosis
Zipponi, M., Cacciottola, L., Camboni, A., Stratopoulou, C. A., Taylor, H. S., & Dolmans, M. (2024) · Molecular Human Reproduction · doi:10.1093/molehr/gaae044 · Cited by 11
Hormone receptor profile of ectopic and eutopic endometrium in adenomyosis: a systematic review
Maclean, A., Tipple, L., Newton, E., & Hapangama, D. K. (2025) · Human Reproduction Open · doi:10.1093/hropen/hoaf002 · Cited by 12
Applying contrast-enhanced ultrasound model to distinguish atypical focal adenomyosis from uterine leiomyomas
Zhang, Y., Chen, J., Zhu, T., Zhao, A.-X., Zhuang, L.-T., Lu, C.-Y., & Huang, Y. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-4460 · Cited by 11
Exosomes: potential diagnostic markers and drug carriers for adenomyosis
Cheng, W.-X., Wei, S., Zhou, Y., Shao, Y., & Li, M.-Y. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1216149 · Cited by 11
Estrogen 17β‑estradiol accelerates the proliferation of uterine junctional zone smooth muscle cells via the let‑7a/Lin28B axis in adenomyosis
Huang, J., Duan, H., Wang, S., & Wang, Y. (2021) · Molecular Medicine Reports · doi:10.3892/mmr.2021.11976 · Cited by 11
In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis
Philibert, P., Déjardin, S., Pirot, N., Pruvost, A., Nguyen, A. L., Bernex, F., Poulat, F., & Boizet‐Bonhoure, B. (2021) · Molecular Human Reproduction · doi:10.1093/molehr/gaab029 · Cited by 11
Bioinformatic analysis and machine learning to identify the diagnostic biomarkers and immune infiltration in adenomyosis
Liu, D., Yin, X., Guan, X., & Li, K. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2022.1082709 · Cited by 11
Coexistence of uterine adenomyosis is not associated with a better prognosis in endometrioid-type endometrial cancer
Aslan, K., Sarı, M. E., Yalçın, H. R., Yalçın, İ., Cüylan, Z. F., & Özdal, B. (2020) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-020-02172-z · Cited by 11
Individualized conservative therapeutic strategies for adenomyosis with the aim of preserving fertility
Han, L., Liu, Y., Lao, K., Jiang, J., Zhang, C., & Wang, Y. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1133042 · Cited by 10
Non-Coding RNAs (microRNAs, lncRNAs, circRNAs) in Adenomyosis: A Systematic Review of Mechanistic and Translational Evidence
Watrowski, R., Kostov, S. G., Palumbo, M., Rosati, A., Sparić, R., Alkatout, İ., Juhasz‐Böss, I., Vitale, S. G., & Mereu, L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110713 · Cited by 10
Comparing gene expression in deep infiltrating endometriosis with adenomyosis uteri: evidence for dysregulation of oncogene pathways
Marshall, A., Kommoss, K. S., Ortmann, H., Kirchner, M., Jauckus, J., Sinn, H., Strowitzki, T., & Germeyer, A. (2023) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-023-01083-9 · Cited by 10
Association between the occurrence of adenomyosis and the clinical outcomes of vaginal repair of cesarean section scar defects: an observational study
Chen, H., Wang, W., Wang, H., & Wang, X. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04529-x · Cited by 10
Abnormal activation of the Wnt3a/β-catenin signaling pathway promotes the expression of T-box transcription factor 3(TBX3) and the epithelial-mesenchymal transition pathway to mediate the occurrence of adenomyosis
Li, M., Li, T., Jin, T., Chen, Y., Cheng, L., Liang, Q., Yan, S., Li, T., Ran, Q., & Chen, W. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08870-y · Cited by 9
From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis
Li, B., Qi, J., Cao, Y., Long, Y., Wei, Z., Wang, W., Hu, S., Wang, Y., Zhu, Q., Hu, X. J., et al. (2025) · Advanced Science · doi:10.1002/advs.202411752 · Cited by 10
RNA-seq reveals co-dysregulated circular RNAs in the adenomyosis eutopic endometrium and endometrial–myometrial interface
Guo, Z., Duan, H., Wang, S., Wang, S., Lin, Q., & Li, Y. (2022) · BMC Women s Health · doi:10.1186/s12905-022-01871-2 · Cited by 9
Shorter Anogenital Distance in Women with Ovarian Endometriomas and Adenomyosis, but Not Uterine Leiomyomas
Liu, X., Ding, D., Shen, M., Yan, D., & Guo, S. (2023) · Biomedicines · doi:10.3390/biomedicines11102618 · Cited by 9
Adjuvant therapy of Chinese herbal medicine for the treatment of adenomyosis
Huang, L. T., Ji, X., Wang, X., Wu, Y., Luo, M., Hao, X., & Wei, S. (2020) · Medicine · doi:10.1097/md.0000000000020560 · Cited by 9
Sonographic and clinical features of adenomyosis in women in "early" (18-35) and "advanced" (>35) reproductive ages
Piccioni, M. G., Rosato, E., Muzii, L., Perniola, G., & Porpora, M. G. (2021) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.21.04755-2 · Cited by 9
Diagnostic gene biomarkers for predicting immune infiltration in endometriosis
Xie, C., Lu, C., Liu, Y., & Liu, Z. (2022) · BMC Women s Health · doi:10.1186/s12905-022-01765-3 · Cited by 9
Perioperative Suppression of Schwann Cell Dedifferentiation Reduces the Risk of Adenomyosis Resulting from Endometrial–Myometrial Interface Disruption in Mice
Wang, X., Liu, X., & Guo, S. (2022) · Biomedicines · doi:10.3390/biomedicines10061218 · Cited by 9
Claudin-10 Expression Is Increased in Endometriosis and Adenomyosis and Mislocalized in Ectopic Endometriosis
Löffelmann, A., Hoerscher, A., Riaz, M. A., Zeppernick, F. A., Meinhold-Heerlein, I. M., & Konrad, L. (2022) · Diagnostics · doi:10.3390/diagnostics12112848 · Cited by 9
Progression of adenomyosis magnetic resonance imaging features under ulipristal acetate for symptomatic fibroids
Calderon, L., Netter, A., Grob, A., Mancini, J., Siles, P., Vidal, V., & Agostini, A. (2020) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2020.11.012 · Cited by 9
Human Endometrial Pericytes: A Comprehensive Overview of Their Physiological Functions and Implications in Uterine Disorders
Tang, Y., Frisendahl, C., Piltonen, T., Arffman, R. K., Lalitkumar, P. G., & Gemzell‐Danielsson, K. (2024) · Cells · doi:10.3390/cells13171510 · Cited by 8
Effects of pretreatment strategies on fertility outcomes in patients with adenomyosis
Moawad, G., Youssef, Y., Fruscalzo, A., Khedhri, S., Faysal, H., Pirtea, P., Guani, B., Vallée, A., Ayoubi, J. M., & Féki, A. (2024) · Frontiers in Reproductive Health · doi:10.3389/frph.2024.1484202 · Cited by 10
Differences in the Sonographic Features of Adenomyosis and Concurrent Endometriosis Compared to Isolated Adenomyosis
Matot, R., Blickstein, O., Leibner, G., Bar-Peled, U., Borovich, A., Geron, Y., Gilboa, Y., Krissi, H., & Perlman, S. (2025) · Journal of Ultrasound in Medicine · doi:10.1002/jum.16667 · Cited by 8
Clinical efficacy of myometrial and endometrial microwave ablation in the treatment of patients with adenomyosis who had anemia
Li, Z., Li, X., Lin, M., Qiu, S., Wang, L., Lai, L., Luo, X., Mo, Z., Dong, G., Lyu, G., et al. (2022) · International Journal of Hyperthermia · doi:10.1080/02656736.2022.2131001 · Cited by 8
RETRACTED: Dye diffusion during laparoscopic tubal patency tests may suggest a lymphatic contribution to dissemination in endometriosis: A prospective, observational study
Scioscia, M., Pesci, A., Scardapane, A., Noventa, M., Bonaccorsi, G., Greco, P., & Zamboni, G. (2019) · PLoS ONE · doi:10.1371/journal.pone.0226264 · Cited by 8
Retracted
Mutation profile and chromosomal abnormality in adenomyosis
Suda, K., Takahashi, K., Tamura, R., Saito, K., Yamaguchi, M., Yachida, N., Adachi, S., Kase, H., Okuda, S., Yoshihara, K., et al. (2025) · Reproduction · doi:10.1530/rep-25-0132 · Cited by 7
Exploring the Endocrine Mechanisms in Adenomyosis: From Pathogenesis to Therapies
d’Otreppe, J., Patiño-García, D., Piekos, P., de Codt, M., Manavella, D. D., Courtoy, G. E., & Orellana, R. (2024) · Endocrines · doi:10.3390/endocrines5010004 · Cited by 8
Neonatal feeding of an estrogen receptor β agonist induces external adenomyosis-like lesions in ICR mouse
Cao, Y., Wang, X., Liu, X., Harada, T., & Guo, S. (2022) · Reproductive and Developmental Medicine · doi:10.1097/rd9.0000000000000012 · Cited by 7
Adenomyosis in Pregnancy—Should It Be Managed in High-Risk Obstetric Units?
Orozco, R., Jiménez, J. C. V., Garcia, I. B., Lozano, M., Hernández, G., Pérez-Rey, D., Meloni, L., & Alcázar, J. L. (2023) · Diagnostics · doi:10.3390/diagnostics13061184 · Cited by 7
Evaluation of Association Between Adenomyosis and Cesarean Scar Defect
Katouli, F. S., Zebardast, J., Tavoli, Z., Bayani, L., Azizinik, F., Moradpour, M., Mardani, R., Meimani, N., & Fathi, S. (2023) · Journal of Ultrasound in Medicine · doi:10.1002/jum.16388 · Cited by 7
Performing laparoscopic adenomyomectomy with the four-petal method
Kuo, H.-H., Weng, C. H., Jaiswal, A., Wu, K., Wang, C., Lee, C., & Yen, C. (2020) · Fertility and Sterility · doi:10.1016/j.fertnstert.2020.07.032 · Cited by 7
ITRAQ-based proteomics analysis of tanshinone IIA on human ectopic endometrial stromal cells of adenomyosis
Luo, Y., Li, Z.-M., Li, L., Zou, Y., Xu, X., Zhang, Z., Liu, F., Xiong, Y., & Wan, L. (2021) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-020-05936-1 · Cited by 7
Adenomyosis in Pregnancy: Diagnostic Pearls and Pitfalls
Jensen, K. K., Pyle, C., Foster, B. R., Sohaey, R., & Oh, K. Y. (2021) · Radiographics · doi:10.1148/rg.2021200120 · Cited by 7
Causal association between telomere length and female reproductive endocrine diseases: a univariable and multivariable Mendelian randomization analysis
Yang, Q., Zhang, J., & Fan, Z. (2024) · Journal of Ovarian Research · doi:10.1186/s13048-024-01466-5 · Cited by 7
Inhibition of lysine-specific histone demethylase 1A suppresses adenomyosis through reduction in ectopic endometrial stromal cell proliferation, migration, and invasion
Cui, L., Sang, C., Li, R., & Zhao, S. (2024) · CytoJournal · doi:10.25259/cytojournal_48_2024 · Cited by 6
Diagnostic Accuracy of Ultrasound for Adenomyosis—A Blinded, Retrospective, Single-Expert Validation Study of the 2022 MUSA Guidelines
Maghsoudlou, P., Chatroux, L. R., Ajao, M. O., King, L. P., & Groszmann, Y. S. (2025) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2025.07.024 · Cited by 6
Proliferative characteristics of eutopic and ectopic endometrium in adenomyosis using AgNOR technology
Metreveli, B., Gagua, D., Burkadze, G., & Kepuladze, S. (2023) · GEORGIAN SCIENTISTS · doi:10.52340/gs.2023.05.01.04 · Cited by 6
miR-141-3p Regulates the Proliferation and Apoptosis of Endometrial-Myometrial Interface Smooth Muscle Cells in Adenomyosis Via JAK2/STAT3 Pathway
Wang, S., Duan, H., Wang, S., Guo, Z., & Lin, Q. (2023) · Biochemical Genetics · doi:10.1007/s10528-023-10508-4 · Cited by 6
Estrogen attenuates stiffness-driven fibrotic signaling via transcriptional regulation
Zhu, H., Wang, J., Liu, Y., Wang, X., Lu, T. J., Feng, X., & Lin, M. (2025) · Biophysical Journal · doi:10.1016/j.bpj.2025.05.007 · Cited by 6
Successful conservative treatment for massive uterine bleeding with non-septic disseminated intravascular coagulation after termination of early pregnancy in a woman with huge adenomyosis: case report
Kimura, F., Takahashi, A., Kitazawa, J., Yoshino, F., Katsura, D., Amano, T., & Murakami, T. (2020) · BMC Women s Health · doi:10.1186/s12905-020-00924-8 · Cited by 6
Endométriose et adénomyose
Just, P., Moret, S., Borghese, B., & Chapron, C. (2021) · Annales de Pathologie · doi:10.1016/j.annpat.2021.03.012 · Cited by 7
Impact of Uterine Adenomyosis on Pregnancy Outcomes in Women Undergoing In Vitro Fertilization Treated With a Long-Term Pituitary Downregulation Protocol
Zhang, J., Hu, L., Bu, Z., & Sun, Y. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.655803 · Cited by 6
SKP2 regulates ZEB1 expression and stimulates eutopic endometrial stromal cell invasion and proliferation of adenomyosis
Guo, Y., Wang, J., Jia, C., & Liao, Y. (2021) · Reproductive Biology · doi:10.1016/j.repbio.2021.100578 · Cited by 6
Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice
Heinosalo, T., Rytkönen, K. T., Saarinen, N., Järvensivu, P., Damdimopoulou, P., Strauss, L., Orasniemi, S., Horshauge, P., Gabriel, M., Koskimies, P., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23094815 · Cited by 6
Analysis of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP, MMP14) in Eutopic and Ectopic Endometrium and in Serum and Endocervical Mucus of Endometriosis
Maoga, J. B., Riaz, M. A., Mwaura, A. N., Mecha, E. O., Omwandho, C. O. A., Scheiner‐Bobis, G., Meinhold-Heerlein, I. M., & Konrad, L. (2023) · Biomedicines · doi:10.3390/biomedicines11102730 · Cited by 6
Macrophage polarization in adenomyosis: A review
Qiu, Y., Cao, J., Li, S., Liu, Y., Wan, G., & Gui, T. (2024) · American Journal of Reproductive Immunology · doi:10.1111/aji.13841 · Cited by 7
Adenomyosis associated with endometrial cancer: Possible correlation with pathological, immunohistochemical and molecular characteristics
Torre, F. L., Hurni, Y., Farsi, E., Nardi, E., Castiglione, F., Sorbi, F., Petrella, M. C., Fambrini, M., & Petraglia, F. (2025) · Gynecologic Oncology · doi:10.1016/j.ygyno.2025.02.017 · Cited by 5
Proteomic detection of COX-2 pathway-related factors in patients with adenomyosis
Zhang, J., Shi, L., Duan, J., Li, M., & Li, C. (2024) · PeerJ · doi:10.7717/peerj.16784 · Cited by 6
Endometriosis, a Familiar Companion of Isthmocele: A Systematic Review and Meta-Analysis
Gulz, M., Vidal, À., Kalaitzopoulos, D. R., Karrer, T., & Mueller, M. D. (2025) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2025.06.012 · Cited by 6
Adenomyosis: clinical aspects, impact on fertility and pregnancy outcome
Gabidullina, R. I., Игоревна, К. А., Артуровна, К. Е., NUHBALA, F. R., Bagirli, R. R., Mingaleva, E. R., & Айратовна, Х. Э. (2020) · GYNECOLOGY · doi:10.26442/20795696.2020.4.200264 · Cited by 5
Diverticulum-like Adenomyosis on the Cesarean Scars of the Uterus: A Rare Type of Cystic Adenomyosis
Yang, X., Zhu, L., Zhao, R., Shen, T., Huang, X., & Chen, Z. (2022) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2022.02.008 · Cited by 5
Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis
Maoga, J. B., Riaz, M. A., Mwaura, A. N., Scheiner‐Bobis, G., Mecha, E. O., Omwandho, C. O. A., Meinhold-Heerlein, I. M., & Konrad, L. (2022) · Diagnostics · doi:10.3390/diagnostics12040779 · Cited by 5
Methods of diagnostics of adenomyosis: a systematic review
Adamyan, L. V., Sokolov, A. D., Avetisyan, J. S., & Shapovalenko, R. (2023) · Russian Journal of Human Reproduction · doi:10.17116/repro20232903181 · Cited by 5
Adenomyotic glands are highly related to endometrial glands
Maier, V., Höll, M., Dietze, R., Mecha, E. O., Omwandho, C. O. A., Tinneberg, H., Meinhold-Heerlein, I. M., & Konrad, L. (2019) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2019.11.007 · Cited by 5
Integrating Network Pharmacology and Experimental Validation Deciphers the Mechanism of Guizhi Fuling Wan against Adenomyosis
Wang, H., Zhang, J., Zhu, Q., Fu, X., & Li, C. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/6034147 · Cited by 5
Transitional Lesions, One More Step Towards Understanding the Pathogenesis of Adenomyosis
Wacheul, E., Dolmans, M., Ambroise, J., Donnez, J., & Camboni, A. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14134578 · Cited by 4
Pathogenesis of Adenomyosis: An Integrated Review of Cellular Origins, Molecular Mechanisms, and Intersecting Diseases
Yang, J., Li, X., Yu, P. E. N. G., Sun, Z., Zhang, L., Duan, J., & Zhong, N. A. (2026) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.71129 · Cited by 4
Myometrial wall thickness ratio—A nomogram reference for diagnosing myometrial wall asymmetry
Garcia, D., Ivañez-Muñoz, M., Salazar, B., Ramirez, B., Olaso, F., & Alcázar, J. L. (2022) · Journal of Clinical Ultrasound · doi:10.1002/jcu.23189 · Cited by 4
The Value of Adenomyosis Type in Clinical Assessment: A Single-center Experience of 755 Nodular and Diffuse Adenomyosis Cases
Demirtaş, G. S., & Uyar, İ. (2021) · Archives of Iranian Medicine · doi:10.34172/aim.2021.54 · Cited by 4
Breastfeeding history and adenomyosis risk using a novel case-control study design
Hall, M. S., Holt, V. L., Holzman, C., Vazquez, A. I., Harris, H. R., As‐Sanie, S., & Upson, K. (2022) · Fertility and Sterility · doi:10.1016/j.fertnstert.2022.12.028 · Cited by 4
Adenomyosis and uterine stiffness: what is the chicken? Which is the egg?
Munro, M. G. (2023) · Human Reproduction · doi:10.1093/humrep/dead046 · Cited by 4
Magnetic resonance imaging presentation of diffuse and focal adenomyosis before and after pregnancy
Marcellin, L., LEGAY, L., Santulli, P., Millischer, A., Bordonné, C., Maitrot‐Mantelet, L., Maignien, C., Bourdon, M., Gaudet-Chardonnet, A., Borghese, B., et al. (2023) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2023.02.008 · Cited by 3
Updates on adenomyosis and fertility
Shats, M., Zajicek, M., Siedhoff, M. T., & Meyer, R. (2025) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000001039 · Cited by 3
Phenotypic heterogeneity in adenomyosis: internal and external subtypes
Liang, Y., Zhu, M., Sun, F., Liu, X., Liu, J., & Zhang, J. (2025) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-025-08166-5 · Cited by 3
Aortic mural thrombosis with bilateral renal infarction in a woman taking dienogest for adenomyosis: A case report and literature review
Lee, K.-Y., Cheng, C., & Chiang, Y. (2025) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2024.08.015 · Cited by 3
Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b + CD146 + Fibroblast Differentiation
Ye, Z., Zhao, A., Li, X., Hao, Y., Huang, D., Chen, J., Li, T., Dai, Y., Sun, W., Ma, L., et al. (2025) · Advanced Science · doi:10.1002/advs.202507128 · Cited by 6
The ADELIN analysis: the presence of ADenomyosis and its effects on matErnal, neonataL, and obstetrIc outcomes: a systematic review and meta-aNalysis
Etrusco, A., Agrifoglio, V., D’Amato, A., Nigris, A. D., Maggiore, U. L. R., Donna, M. C. D., Riemma, G., & Cozzolino, M. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.11.008 · Cited by 5
Deciphering the relationship between adenomyosis and the microbiota: a systematic review
Ateş, Ç., Dilbaz, B., & Saçıntı, K. G. (2025) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2025.114823 · Cited by 4

Authors: García-Solares, J., Donnez, J., Donnez, O., & Dolmans, M.-M.
Affiliations: UCLouvain (BE)
Cliniques Universitaires Saint-Luc (BE)
Corresponding author: Dolmans, Marie-Madeleine
ORCID: Donnez, Jacques
Donnez, Olivier
Dolmans, Marie-Madeleine
Venue: Fertility and Sterility
Publisher: Elsevier BV
Published: 2018-03
Volume: 109
Issue: 3
Pages: 371-379
ISSN: 0015-0282 (ISSN-L)
DOI: 10.1016/j.fertnstert.2017.12.030
OpenAlex: W2794246050
Cited by: 339
References: 100
Citations by year: 2026: 39 · 2025: 46 · 2024: 33 · 2023: 48 · 2022: 57 · 2021: 53 · 2020: 41 · 2019: 17 · 2018: 4
FWCI: 4.55
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1548 d)
Locations: Fertility and Sterility (publishedVersion)
PubMed (publishedVersion)
Digital Access to Libraries (Université catholique de Louvain (UCL), l'Université de Namur (UNamur) and the Université Saint-Louis (USL-B)) (submittedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Health Sciences › Medicine › Obstetrics and Gynecology › Uterine Myomas and Treatments
Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
Keywords: adenomyosis, pathogenesis, metaplasia, Müllerian remnants, stem cell differentiation, epithelial-mesenchymal transition, collective cell migration, baboon model, myometrium, estrogen-dependent disease
MeSH terms: Animals, Cell Movement, Estradiol, Female, Humans, Metaplasia, Mullerian Ducts, Time Factors, Uterine Diseases, Uterus, Signal Transduction, Disease Progression, Pluripotent Stem Cells, Epigenesis, Genetic, Embryonic Stem Cells, Adult Stem Cells, Epithelial-Mesenchymal Transition, Adenomyosis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Pathogenesis of uterine adenomyosis, invagination or metaplasia?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks