Toxic pelvic cavity in endometriosis, a new frontier for medical therapies
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Inflammatory conditions in the pelvic cavity, with elevated cytokines and other inflammatory markers, create a toxic environment for gametes and early-stage embryos.
“This concept outlines that inflammatory conditions prevailing in the pelvic cavity-with an elevation of a slew of cytokines and other markers of inflammation-constitute a toxic environment for gametes and early-stage embryos (31).”
From Endometrial receptivity in adenomyosis and/or endometriosis (2023) · cites this paper as [31]
The main mechanism believed to reduce natural conception in endometriosis is a pelvic toxic condition that interferes with sperm-oocyte interactions.
“Today, the primary mechanism by which endometriosis is believed to hamper the chances of natural conception is the pelvic toxic condition that interferes with sperm-oocyte interactions (31).”
From Endometrial receptivity in adenomyosis and/or endometriosis (2023) · cites this paper as [31]
Cites
Endometriosis and infertility: pathophysiology and management
de Ziegler, D., Borghese, B., & Chapron, C. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60490-4 · Cited by 836 · see citing works
Surgery for endometriosis-associated infertility: a pragmatic approach
Vercellini, P., Somigliana, E., Vigano, P., Abbiati, A., Barbara, G., & Crosignani, P. G. (2009) · Human Reproduction · doi:10.1093/humrep/den379 · Cited by 269 · see citing works
Cicinelli, E., Trojano, G., Mastromauro, M., Vimercati, A., Marinaccio, M., Mitola, P. C., Resta, L., & de Ziegler, D. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.05.016 · Cited by 147 · see citing works
Juneau, C., Kraus, E., Werner, M., Franasiak, J., Morin, S., Patounakis, G., Molinaro, T., de Ziegler, D., & Scott, R. T. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.05.038 · Cited by 93 · see citing works
Lee, Y. H., Yang, J. X., Allen, J. C., Tan, C. S., Chern, B. S. M., Tan, T. Y., Tan, H. H., Mattar, C. N. Z., & Chan, J. K. Y. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.05.003 · Cited by 30 · see citing works
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Endometrial receptivity in adenomyosis and/or endometriosis
Pirtea, P., de Ziegler, D., & Ayoubi, J. M. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.03.004 · Cited by 65 · see citing works
Self-citation
- Authors
- de Ziegler, D., Pirtea, P., Poulain, M., Carbonel, M., Even, M., & Ayoubi, J. M.
- Affiliations
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 110
- Issue
- 4
- Pages
- 644-645
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2891625516
- Cited by
- 6
- References
- 5
- Citations by year
- 2024: 1 · 2023: 2 · 2022: 2 · 2019: 1
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, pelvic cavity, medical therapy, risk factors, age at menarche, menstrual cycle length, oral contraceptives, multiparity, body mass index
- MeSH terms
- Animals, Ascitic Fluid, Ceramides, Endometriosis, Female, Humans, Infertility, Oocytes, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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