Higher prevalence of chronic endometritis in women with endometriosis: a possible etiopathogenetic link
Open accessAbstract
Objective To evaluate the association between endometriosis end chronic endometritis (CE) diagnosed by hysteroscopy, conventional histology, and immunohistochemistry.Design Case-control study.Setting University hospital.Patient(s) Women with and without endometriosis who have undergone hysterectomy.Intervention(s) Retrospective evaluation of 78 women who have undergone hysterectomy and were affected by endometriosis and 78 women without endometriosis.Main outcome measure(s) CE diagnosed based on conventional histology and immunohistochemistry with anti-syndecan-1 antibodies to identify CD138 cells.Result(s) The prevalence of CE was statistically significantly higher in the women with endometriosis as compared with the women who did not have endometriosis (33 of 78, 42.3% vs. 12 of 78, 15.4% according to hysteroscopy; and 30 of 78, 38.5% vs. 11 of 78, 14.1% according to histology). The women were divided into two groups, 115 patients without CE and 41 patients with CE. With univariate analysis, parity was associated with a lower risk for CE, and endometriosis was associated with a statistically significantly elevated risk of CE. Using multivariate analysis, parity continued to be associated with a lower incidence of CE, whereas endometriosis was associated with a 2.7 fold higher risk.Conclusion(s) The diagnosis of CE is more frequent in women with endometriosis. Although no etiologic relationships between CE and endometriosis can be established, this study suggests that CE should be considered and if necessary ruled out in women with endometriosis, particularly if they have abnormal uterine bleeding. Identification and appropriate treatment of CE may avoid unnecessary surgery.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Chronic endometritis, which is more prevalent in endometriosis, does not appear to affect implantation rates after euploid blastocyst transfers in estradiol and progesterone cycles.
“Chronic endometritis, which has an increased prevalence in endometriosis (17), does not seem to affect implantation rates after transfers of euploid blastocysts in E 2 and progesterone cycles (18).”
From Endometrial receptivity in adenomyosis and/or endometriosis (2023) · cites this paper as [17]
Endometriosis is associated with higher concentrations of Escherichia coli in menstrual blood, with vaginal infections, and with chronic endometritis.
“Endometriosis is associated with higher concentrations of Escherichia coli in menstrual blood (134, 135), with vaginal infections (136), and with chronic endometritis (137).”
From Pathogenesis of endometriosis: The genetic/epigenetic theory (2019) · cites this paper as [137]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
1 retracted
Siristatidis, C. S., Nissotakis, C., Chrelias, C., Iacovidou, H., & Salamalekis, E. (2006) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2006.00373.x · Cited by 93 · see citing works
RetractedRevised American Society for Reproductive Medicine classification of endometriosis: 1996
American Society for Reproductive Medicine (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81391-x · Cited by 3,018 · see citing works
Sampson, J. A. (1927) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(15)30003-x · Cited by 2,334 · see citing works
Immunobiology of endometriosis
Lebovic, D. I., Mueller, M. D., & Taylor, R. N. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(00)01630-7 · Cited by 857 · see citing works
Cicinelli, E., Matteo, M., Tinelli, R., Lepera, A., Alfonso, R., Indraccolo, U., Marrocchella, S., Greco, P., & Resta, L. (2014) · Human Reproduction · doi:10.1093/humrep/deu292 · Cited by 525 · see citing works
Self-citationHOX gene expression is altered in the endometrium of women with endometriosis
Taylor, H. S. (1999) · Human Reproduction · doi:10.1093/humrep/14.5.1328 · Cited by 372 · see citing works
Bouet, P.-E., El Hachem, H., Monceau, E., Gariépy, G., Kadoch, I.-J., & Sylvestre, C. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.09.025 · Cited by 335 · see citing works
The role of cytokines in endometriosis
Wu, M., & Ho, H. (2003) · American Journal of Reproductive Immunology · doi:10.1034/j.1600-0897.2003.01207.x · Cited by 317 · see citing works
Cicinelli, E., de Ziegler, D., Nicoletti, R., Colafiglio, G., Saliani, N., Resta, L., Rizzi, D., & Vito, D. D. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.03.074 · Cited by 282 · see citing works
Self-citationPregnancy outcomes in women with chronic endometritis and recurrent pregnancy loss
McQueen, D. B., Perfetto, C. O., Hazard, F. K., & Lathi, R. B. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.06.044 · Cited by 262 · see citing works
Hickey, M., Ballard, K., & Farquhar, C. M. (2014) · BMJ · doi:10.1136/bmj.g1752 · Cited by 223 · see citing works
Chronic endometritis: morphologic and clinical observations.
Greenwood, S. M., & Moran, J. J. R. (1981) · PubMed · Cited by 215 · see citing works
The impact of chronic endometritis on reproductive outcome
Kasius, J. C., Fatemi, H. M., Bourgain, C., Go, D. M. D. S., Eijkemans, M. J. C., Fauser, B. C. J. M., Devroey, P., & Broekmans, F. J. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.09.039 · Cited by 213 · see citing works
Endometrial micropolyps at fluid hysteroscopy suggest the existence of chronic endometritis
Cicinelli, E., Resta, L., Nicoletti, R., Zappimbulso, V., Tartagni, M., & Saliani, N. (2005) · Human Reproduction · doi:10.1093/humrep/deh779 · Cited by 205 · see citing works
Self-citationMacrophage expression in endometrium of women with and without endometriosis
Berbic, M., Schulke, L., Markham, R., Tokushige, N., Russell, P. J., & Fraser, I. S. (2008) · Human Reproduction · doi:10.1093/humrep/den393 · Cited by 204 · see citing works
Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis
Khan, K. N., Kitajima, M., Hiraki, K., Yamaguchi, N., Katamine, S., Matsuyama, T., Nakashima, M., Fujishita, A., Ishimaru, T., & Masuzaki, H. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.04.053 · Cited by 195 · see citing works
Endometriosis: where are we and where are we going?
Greene, A. D., Lang, S. A., Kendziorski, J. A., Sroga-Rios, J. M., Herzog, T. J., & Burns, K. A. (2016) · Reproduction · doi:10.1530/rep-16-0052 · Cited by 187 · see citing works
Senapati, S., Sammel, M. D., Morse, C. B., & Barnhart, K. T. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.03.037 · Cited by 179 · see citing works
Differential macrophage infiltration in early and advanced endometriosis and adjacent peritoneum
Khan, K. N., Masuzaki, H., Fujishita, A., Kitajima, M., Sekine, I., & Ishimaru, T. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.07.037 · Cited by 161 · see citing works
Yang, R. J., Du, X., Wang, Y., Song, X., Yang, Y., & Qiao, J. (2014) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-013-3131-2 · Cited by 155 · see citing works
Intra-uterine microbial colonization and occurrence of endometritis in women with endometriosis†
Khan, K. N., Fujishita, A., Kitajima, M., Hiraki, K., Nakashima, M., & Masuzaki, H. (2014) · Human Reproduction · doi:10.1093/humrep/deu222 · Cited by 155 · see citing works
The Association between Endometriosis and Chronic Endometritis
Takebayashi, A., Kimura, F., Kishi, Y., Ishida, M., Takahashi, A., Yamanaka, A., Takahashi, K., Suginami, H., & Murakami, T. (2014) · PLoS ONE · doi:10.1371/journal.pone.0088354 · Cited by 153 · see citing works
Pietro, C. D., Cicinelli, E., Guglielmino, M. R., Ragusa, M., Farina, M., Palumbo, M. A., & Cianci, A. (2013) · American Journal of Reproductive Immunology · doi:10.1111/aji.12076 · Cited by 143 · see citing works
Self-citationPrevalence of chronic endometritis in recurrent miscarriages
Kitaya, K. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.09.061 · Cited by 143 · see citing works
KOBAYASHI, H., HIGASHIURA, Y., SHIGETOMI, H., & KAJIHARA, H. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1755 · Cited by 133 · see citing works
Diagnosis and treatment of unexplained infertility.
Quaas, A. M., & Dokras, A. (2008) · PubMed · Cited by 126 · see citing works
Endometriosis: abnormal endometrium and dysfunctional immune response
Braun, D. P., & Dmowski, W. P. (1998) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/00001703-199810000-00003 · Cited by 123 · see citing works
Matteo, M., Cicinelli, E., Greco, P., Massenzio, F., Baldini, D., Falagario, T., Rosenberg, P., Castellana, L., Specchia, G., & Liso, A. (2009) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2009.00698.x · Cited by 120 · see citing works
Self-citationImmunological aspects of endometriosis
Vinatier, D. (1996) · Human Reproduction Update · doi:10.1093/humupd/2.5.371 · Cited by 113 · see citing works
Angiogenesis and Macrophage Activation in Endometriosis
TAYLOR, R. N., RYAN, S. P., MOORE, E. S., HORNUNG, D., SHIFREN, J. L., & TSENG, J. F. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb48540.x · Cited by 113 · see citing works
Molecular biology of endometriosis: from aromatase to genomic abnormalities
Monsivais, D., Kakinuma, T., Furukawa, Y., Bernardi, L., Pavone, M., Dyson, M., & Bulun, S. (2015) · Seminars in Reproductive Medicine · doi:10.1055/s-0035-1554053 · Cited by 112 · cited 1× · see citing works
“Recent work has added other factors, including genetics and epigenetics (16).”
Altered uterine contractility in women with chronic endometritis
Pinto, V., Matteo, M., Tinelli, R., Mitola, P. C., de Ziegler, D., & Cicinelli, E. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.01.007 · Cited by 90 · see citing works
Self-citationChronic endometritis: The role of immunohistochemistry in the detection of plasma cells
Crum, C. P., EGAWA, K., Fenoglio, C. M., & Richart, R. M. (1983) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(83)90045-5 · Cited by 77 · see citing works
Increased rate of spontaneous miscarriages in endometriosis-affected women
Santulli, P., Marcellin, L., Menard, S., Thubert, T., Khoshnood, B., Gayet, V., Goffinet, F., Ancel, P.-Y., & Chapron, C. (2016) · Human Reproduction · doi:10.1093/humrep/dew035 · Cited by 72 · see citing works
Lin, W.-C., Chang, C. Y.-Y., Hsu, Y.-A., Chiang, J.-H., & Wan, L. (2016) · Medicine · doi:10.1097/md.0000000000002773 · Cited by 70 · see citing works
Correspondence between hysteroscopic and histologic findings in women with chronic endometritis
Cicinelli, E., Tinelli, R., Lepera, A., Pinto, V., Fucci, M. R., & Resta, L. (2010) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349.2010.498496 · Cited by 67 · see citing works
Self-citationOptimal uterine anatomy and physiology necessary for normal implantation and placentation
de Ziegler, D., Pirtea, P., Galliano, D., Cicinelli, E., & Meldrum, D. R. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.02.023 · Cited by 67 · see citing works
Self-citationMiguel, R. D. V., Chivukula, M., Krishnamurti, U., Amortegui, A. J., Kant, J. A., Sweet, R. L., Wiesenfeld, H. C., Phillips, J. M., & Cherpes, T. L. (2011) · Pathology - Research and Practice · doi:10.1016/j.prp.2011.08.007 · Cited by 62 · see citing works
Apoptosis and the Pathogenesis of Endometriosis
García-Velasco, J. A., & Arici, A. M. (2003) · Seminars in Reproductive Medicine · doi:10.1055/s-2003-41323 · Cited by 62 · see citing works
Immunohistochemical characterization of leucocyte subpopulations in endometriotic lesions
Oosterlynck, D. J., Cornillie, F. J., Waer, M., & Koninckx, P. R. (1993) · Archives of Gynecology and Obstetrics · doi:10.1007/bf02766646 · Cited by 50 · see citing works
High prevalence of endometrial polyps in endometriosis-associated infertility
Shen, L., Wang, Q., Huang, W., Wang, Q., Yuan, Q., Huang, Y., & Lei, H. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.04.067 · Cited by 50 · see citing works
Histology of micro polyps in chronic endometritis
Resta, L., Palumbo, M., Rossi, R., Piscitelli, D., Fiore, M. G., & Cicinelli, E. (2012) · Histopathology · doi:10.1111/j.1365-2559.2011.04099.x · Cited by 40 · see citing works
Self-citationGazvani, R., Smith, L., & Fowler, P. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(01)02954-5 · Cited by 40 · see citing works
Endometrial polyps in infertile patients: do high concentrations of interferon-gamma play a role?
Mollo, A., Stile, A., Alviggi, C., Granata, M., Placido, G. D., Perrella, A., D'Antonio, A., & Cicinelli, E. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.08.001 · Cited by 24 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 2
- Vinatier D, Dufour P, Oosterlynck D. Immunological aspects of endometri- osis. Hum Reprod Update 1996;2:371-84.
- Siristatidis C, Nissotakis C, Chrelias C, Iacovidou H, Salamalekis E. Immuno- logical factors and their role in the genesis and development of endometri- osis. J Obstet Gynecol Res 2006;32:162-70.
Cited by
Sorted by citations
Pathogenesis of endometriosis: The genetic/epigenetic theory
Koninckx, P. R., Ussia, A., Adamyan, L., Wattiez, A., Gomel, V., & Martin, D. C. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.10.013 · Cited by 427 · see citing works
Endometritis: new time, new concepts
Kitaya, K., Takeuchi, T., Mizuta, S., Matsubayashi, H., & Ishikawa, T. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.04.012 · Cited by 308 · see citing works
Review: Chronic endometritis and its effect on reproduction
Kimura, F., Takebayashi, A., Ishida, M., Nakamura, A., Kitazawa, J., Morimune, A., Hirata, K., Takahashi, A., Tsuji, S., Takashima, A., et al. (2019) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.13937 · Cited by 300 · see citing works
Liu, Y., Chen, X., Huang, J., Wang, C.-C., Yu, M.-Y., Laird, S., & Li, T.-C. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.01.022 · Cited by 215 · see citing works
Bacterial contamination hypothesis: a new concept in endometriosis
Khan, K. N., Fujishita, A., Hiraki, K., Kitajima, M., Nakashima, M., Fushiki, S., & Kitawaki, J. (2018) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12083 · Cited by 176 · see citing works
Recurrent implantation failure: reality or a statistical mirage?
Pirtea, P., Cedars, M. I., Devine, K., Ata, B., Franasiak, J. M., Racowsky, C., Toner, J., Scott, R. T., de Ziegler, D., & Barnhart, K. T. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.02.014 · Cited by 115 · see citing works
Shih, A., Adelson, R. P., Vashistha, H., Khalili, H., Nayyar, A., Puran, R., Herrera, R., Chatterjee, P. K., Lee, A. T., Truskinovsky, A. M., et al. (2022) · BMC Medicine · doi:10.1186/s12916-022-02500-3 · Cited by 106 · see citing works
Poli‐Neto, O. B., Meola, J., Silva, J. C. R. E., & Tiezzi, D. G. (2020) · Scientific Reports · doi:10.1038/s41598-019-57207-y · Cited by 97 · see citing works
Xiong, Y., Chen, Q., Chen, C., Tan, J., Wang, Z., Gu, F., & Xu, Y. (2021) · Fertility and Sterility · doi:10.1016/j.fertnstert.2021.03.036 · Cited by 92 · see citing works
Akiyama, K., Nishioka, K., Khan, K. N., Tanaka, Y., Mori, T., Nakaya, T., & Kitawaki, J. (2019) · American Journal of Reproductive Immunology · doi:10.1111/aji.13147 · Cited by 83 · see citing works
Liu, L., Yang, H., Guo, Y., Yang, G., & Chen, Y. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2019.01.006 · Cited by 81 · see citing works
Zhang, Y., Xu, H., Liu, Y., Zheng, S., Zhao, W., Wu, D., Lei, L., & Chen, G. (2019) · American Journal of Reproductive Immunology · doi:10.1111/aji.13177 · Cited by 73 · see citing works
Endometrial receptivity in adenomyosis and/or endometriosis
Pirtea, P., de Ziegler, D., & Ayoubi, J. M. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.03.004 · Cited by 65 · see citing works
Drizi, A., Djokovic, D., Laganà, A. S., & Herendael, B. V. (2020) · Menopause Review/Przegląd Menopauzalny · doi:10.5114/pm.2020.97863 · Cited by 65 · see citing works
Challenges in Clinical Diagnosis and Management of Chronic Endometritis
Yasuo, T., & Kitaya, K. (2022) · Diagnostics · doi:10.3390/diagnostics12112711 · Cited by 59 · see citing works
Assisted reproduction in endometriosis
de Ziegler, D., Pirtea, P., Carbonnel, M., Poulain, M., Cicinelli, E., Bulletti, C., Kostaras, K., Kontopoulos, G., Keefe, D. L., & Ayoubi, J. M. (2018) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2018.10.001 · Cited by 54 · see citing works
Self-citationShi, J., Xu, Q., Yu, S., & Zhang, T. (2025) · Seminars in Immunopathology · doi:10.1007/s00281-025-01040-1 · Cited by 50 · see citing works
Freitag, N., Pour, S. J., Fehm, T. N., Tóth, B., Markert, U. R., Weber, M., Togawa, R., Krüssel, J.-S., Baston-Büst, D. M., & Bielfeld, A. P. (2020) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-020-05679-z · Cited by 50 · see citing works
Vitagliano, A., Cialdella, M., Cicinelli, R., Santarsiero, C. M., Greco, P., Buzzaccarini, G., Noventa, M., & Cicinelli, E. (2021) · Diagnostics · doi:10.3390/diagnostics11122182 · Cited by 49 · see citing works
Self-citationKitaya, K., & Yasuo, T. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032059 · Cited by 46 · see citing works
Mycoplasma genitalium can modulate the local immune response in patients with endometriosis
Campos, G. B., Marques, L. M., Rezende, I. S., Barbosa, M. S., Abrão, M. S., & Timenetsky, J. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.11.009 · Cited by 43 · see citing works
Koninckx, P., Ussia, A., Tahlak, M., Adamyan, L. V., Wattiez, A., Martin, D. C., & Gomel, V. (2019) · PubMed Central · Cited by 52 · see citing works
Menstrual Effluent Provides a Novel Diagnostic Window on the Pathogenesis of Endometriosis
Nayyar, A., Saleem, M. I., Yilmaz, M., DeFranco, M., Klein, G., Elmaliki, K., Kowalsky, E., Chatterjee, P. K., Xue, X., Viswanathan, R., et al. (2020) · Frontiers in Reproductive Health · doi:10.3389/frph.2020.00003 · Cited by 37 · see citing works
Involvement of Transcription Factor 21 in the Pathogenesis of Fibrosis in Endometriosis
Ganieva, U., Nakamura, T., Osuka, S., Bayasula, Nakanishi, N., Kasahara, Y., Takasaki, N., Muraoka, A., Hayashi, S., Nagai, T., et al. (2019) · American Journal Of Pathology · doi:10.1016/j.ajpath.2019.09.008 · Cited by 42 · see citing works
Kato, H., Yamagishi, Y., Hagihara, M., Hirai, J., Asai, N., Shibata, Y., Iwamoto, T., & Mikamo, H. (2022) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2022.01.001 · Cited by 39 · see citing works
Vomstein, K., Reider, S., Böttcher, B., Watschinger, C., Kyvelidou, C., Tilg, H., Moschen, A. R., & Tóth, B. (2022) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2022.103634 · Cited by 38 · see citing works
The pathogenesis, diagnosis, and treatment of chronic endometritis: a comprehensive review
Yan, X., Jiao, J., & Wang, X. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1603570 · Cited by 41 · see citing works
Koninckx, P. R., Ussia, A., Tahlak, M., Adamyan, L., Wattiez, A., Martin, D. C., & Gomel, V. (2019) · Lirias · Cited by 34 · see citing works
Guo, L., Gu, F., Tan, J., Luo, L., Gao, J., & Zhou, C. (2020) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.14541 · Cited by 31 · see citing works
Chronic Endometritis in Fertile and Infertile Women Who Underwent Hysteroscopic Polypectomy
Volodarsky‐Perel, A., Badeghiesh, A. M., Shrem, G., Steiner, N., & Tulandi, T. (2019) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2019.08.017 · Cited by 26 · see citing works
Chronic endometritis: screening, treatment, and pregnancy outcomes in an academic fertility center
HogenEsch, E., Hojjati, R., Komorowski, A. S., Maniar, K. P., Pavone, M. E., Bakkensen, J. B., & Bernardi, L. A. (2023) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-023-02902-z · Cited by 26 · see citing works
Zhang, Y., Li, W., Chen, T., Yang, Y., Wu, M., Jie-ying, L., Gong, Y., & Zou, L. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.578217 · Cited by 25 · see citing works
Gennaro, F. D., Guido, G., Frallonardo, L., Pennazzi, L., Bevilacqua, M., Locantore, P., Vitagliano, A., Saracino, A., & Cicinelli, E. (2025) · Microorganisms · doi:10.3390/microorganisms13010197 · Cited by 24 · see citing works
Self-citationQiao, X., Wu, L., Liu, D., Pei, T., & Huang, W. (2022) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.14326 · Cited by 24 · see citing works
Higher Prevalence of Endometrial Polyps in Infertile Patients with Endometriosis
Zhang, Y., Zhang, Y., Yu, Q., Guo, Z., Ma, J., & Yan, L. (2018) · Gynecologic and Obstetric Investigation · doi:10.1159/000487946 · Cited by 24 · see citing works
Liu, Z., Liu, X., Li, F., Sun, Y., Yu, L., Zhang, W., Zhu, P., Ma, D., Wang, X., Lai, S., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1001437 · Cited by 23 · see citing works
Xiong, Z., Zhang, W., Liu, S., Liu, K., Wang, J., Qin, P., Liu, Y., & Jiang, Q. (2022) · American Journal of Reproductive Immunology · doi:10.1111/aji.13671 · Cited by 20 · see citing works
Kuźmycz, O., & Stączek, P. (2020) · Cancer Biology & Therapy · doi:10.1080/15384047.2020.1736483 · Cited by 19 · see citing works
Keyama, K., Kato, T., Kadota, Y., Erdenebayar, O., Kasai, K., Kawakita, T., Tani, A., Matsui, S., Iwasa, T., Yoshida, K., et al. (2019) · The Journal of Medical Investigation · doi:10.2152/jmi.66.70 · Cited by 20 · see citing works
Should patients be screened for chronic endometritis before assisted reproductive technology?
Cicinelli, E., McQueen, D. B., Huepfel, B. M., Vitagliano, A., Moreno, I., Simón, C., Pirtea, P., Scott, R. T., Bellavia, M., & de Ziegler, D. (2022) · Fertility and Sterility · doi:10.1016/j.fertnstert.2022.08.846 · Cited by 19 · see citing works
Self-citationLi, L., Huang, Q., Duan, X., Han, L., & Peng, D. (2020) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2020.02.004 · Cited by 19 · see citing works
Lin, Y., Li, Y., Li, X., Liu, X., Wang, X., Yu, M., Zhu, Y. Z., & Du, M. (2021) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmab095 · Cited by 19 · see citing works
Li, J., Wei, J., Chen, S., Wang, X., Chen, J., Zeng, D., & Li, F. (2024) · BMC Women s Health · doi:10.1186/s12905-024-03245-2 · Cited by 18 · see citing works
Hiratsuka, D., Matsuo, M., & Hirota, Y. (2026) · Fertility and Sterility · doi:10.1016/j.fertnstert.2026.01.010 · Cited by 18 · see citing works
Kitaya, K., Yasuo, T., & Yamaguchi, T. (2024) · Medicina · doi:10.3390/medicina60060972 · Cited by 18 · see citing works
Chronic endometritis in women with endometriosis-associated infertility
Orazov, M. R., Radzinsky, V. E., Владимировна, В. С., Khamoshina, M. B., Михалева, Л. М., Abitova, M. Z., & Shustova, V. B. (2020) · GYNECOLOGY · doi:10.26442/20795696.2020.3.200174 · Cited by 17 · see citing works
Hiratsuka, D., Matsuo, M., Kashiwabara, K., Inoue, M., Ishizawa, C., Iida, R., Fukui, Y., Aikawa, S., Hiraoka, T., Harada, M., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-92906-9 · Cited by 16 · see citing works
Liu, W., Huang, J., Li, S., Huang, L., Zhang, Q., Nong, Y.-Q., Wei, J.-H., Wu, K., & Liu, F. (2022) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2022.07.020 · Cited by 16 · see citing works
Eutopic endometrial immune profile of infertility-patients with and without endometriosis
Freitag, N., Baston-Büst, D. M., Krüssel, J.-S., Markert, U. R., Fehm, T. N., & Bielfeld, A. P. (2022) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2022.103489 · Cited by 15 · see citing works
Yang, Q., Wang, Y., Cai, H., Zhou, Q., Zeng, L., Li, S. C., Du, H., Wei, W., Zhang, W., Dai, W., et al. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106309 · Cited by 14 · see citing works
Xie, Q., Zhao, C. L., Jiang, W., Li, X., Ni, D., Chen, Y., Li, X., Hua, X., Shen, R., & Ling, X. (2024) · BMC Women s Health · doi:10.1186/s12905-024-03274-x · Cited by 14 · see citing works
Dang, J., Xiao, X., & Li, M. (2024) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-024-03204-8 · Cited by 13 · see citing works
Chronic endometritis: pathogenesis, diagnosis, management and associated infertility
Orazov, M. R., Михалева, Л. М., & Semenov, P. A. (2020) · CLINICAL AND EXPERIMENTAL MORPHOLOGY · doi:10.31088/cem2020.9.2.16-25 · Cited by 15 · see citing works
Inflammation and uterine fibrosis: the possible role of chronic endometritis
de Ziegler, D., Pirtea, P., & Ayoubi, J. M. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2019.02.005 · Cited by 13 · see citing works
Poli‐Neto, O. B., Carlos, D., Favaretto, A. L., Silva, J. C. R. E., Meola, J., & Tiezzi, D. G. (2021) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2021.103307 · Cited by 13 · see citing works
Hysteroscopic findings in chronic endometritis
Marca, A. L., Giorgia, G. A. I. A., Renzini, M. M., Alboni, C., & Mastellari, E. (2021) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.21.04970-8 · Cited by 11 · see citing works
Cicinelli, E., de Ziegler, D., & Vitagliano, A. (2024) · Fertility and Sterility · doi:10.1016/j.fertnstert.2024.02.041 · Cited by 10 · see citing works
Self-citationSiddiqui, S. E., & Bari, V. (2021) · Cureus · doi:10.7759/cureus.20650 · Cited by 11 · see citing works
Strug, M. R., Hartup, L. A., Ryan, E. E., & Lathi, R. B. (2024) · F&S Reviews · doi:10.1016/j.xfnr.2024.100073 · Cited by 11 · see citing works
Higher Chronic Endometritis Incidences within Infertile Polycystic Ovary Syndrome Clinical Cases
Wang, S., Zhao, H., Li, F., Xu, Y., Bao, H., & Zhao, D. (2022) · Journal of Healthcare Engineering · doi:10.1155/2022/9748041 · Cited by 10 · see citing works
RetractedThe role of microbiota in female fertility and infertility
MUZII, L., Tucci, C. D., GALATI, G., MATTEI, G., PIETRANGELI, D., Donato, V. D., PERNIOLA, G., PALAIA, I., & PANICI, P. B. (2022) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.22.04915-6 · Cited by 9 · see citing works
Khan, K. N., de Ziegler, D., & Guo, S. (2024) · Human Reproduction · doi:10.1093/humrep/deae006 · Cited by 7 · see citing works
Gao, Y., Xu, G., Yang, M., Chen, K., & Wang, Y. (2024) · Scientific Reports · doi:10.1038/s41598-024-69095-y · Cited by 8 · see citing works
Radzinsky, V. E., Orazov, M. R., Токтар, Л. Р., Михалева, Л. М., Silant’eva, E. S., Евгеньевич, О. Р., Semenov, P. A., & Владимировна, Л. Е. (2021) · GYNECOLOGY · doi:10.26442/20795696.2021.1.200671 · Cited by 8 · see citing works
Endometriosis: A new perspective on epigenetics and oxidative stress
Guan, Y., Chen, Y., Lin, R., Mo, T., Li, S., Cao, Y., Yin, T., Diao, L., & Li, Y. (2025) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2025.104462 · Cited by 7 · see citing works
Feng, H., Li, C., Chen, J., Li, Z., Ye, X., Hou, L., Wang, C., Hou, C., & Liu, W. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.119861 · Cited by 7 · see citing works
Endometrial Microbiome and Implantation: From Basic Knowledge to Clinical Medicine
Hiratsuka, D., Matsuo, M., & Hirota, Y. (2026) · Reproductive Medicine and Biology · doi:10.1002/rmb2.70040 · Cited by 7 · see citing works
Ye, H., Tian, Y., Yu, X., Li, L., & Hou, M. (2023) · Journal of Women s Health · doi:10.1089/jwh.2023.0300 · Cited by 8 · see citing works
Lin, S., Xie, X., Chen, Y.-S., Wang, Z., Zhang, J., Liu, C., Lin, G. N., Wang, Y., & Guo, Y. (2024) · Reproductive Health · doi:10.1186/s12978-024-01897-9 · Cited by 7 · see citing works
Toxic pelvic cavity in endometriosis, a new frontier for medical therapies
de Ziegler, D., Pirtea, P., Poulain, M., Carbonel, M., Even, M., & Ayoubi, J. M. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.05.018 · Cited by 6 · see citing works
Kitaya, K., Kuroda, K., Jwa, S. C., Kitajima, M., Ono, M., Kikuchi, I., Nakamura, T., Yamasaki, F., Koga, K., Yasuo, T., et al. (2026) · Reproductive Medicine and Biology · doi:10.1002/rmb2.70066 · Cited by 6 · see citing works
Self-citationGawron, I. M., Derbisz, K., Jach, R., Trojnarska, D., Milian-Ciesielska, K., & Pietrus, M. (2025) · BMC Women s Health · doi:10.1186/s12905-025-03632-3 · Cited by 6 · see citing works
Doroftei, B., Ilie, O., Armeanu, T., Stoian, I. L., Anton, N., Babici, R.-G., & Ilea, C. G. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12155069 · Cited by 6 · see citing works
The scattered puzzle effect: implantation disorders in chronic endometritis
Radzinsky, V. E., Orazov, M. R., Токтар, Л. Р., Mihaleva, L. M., Semenov, P. A., Евгеньевич, О. Р., Владимировна, Л. Е., & Silantyeva, E. S. (2020) · GYNECOLOGY · doi:10.26442/20795696.2020.6.200493 · Cited by 6 · see citing works
Irving, J. A., & Clement, P. B. (2019) · Springer eBooks · doi:10.1007/978-3-319-46334-6_13 · Cited by 6 · see citing works
Endometriosis-associated Symptoms and Diagnostic Delay: An Online Survey
Moradi, M., Niazi, A., Parker, M. A., Sneddon, A., López, V., & Ellwood, D. A. (2022) · Journal of Obstetrics Gynecology and Cancer Research · doi:10.30699/jogcr.7.6.479 · Cited by 6 · see citing works
Orazov, M. R., Radzinskiy, V. E., Костин, И. Н., Gagaev, C. G., & Евгеньевич, О. Р. (2021) · Gynecological Endocrinology · doi:10.1080/09513590.2021.2006437 · Cited by 5 · see citing works
Dumančić, S., Jakovac, M. B., Mimica, M. D., Tomaš, S. Z., & Marušić, J. (2025) · Life · doi:10.3390/life15020240 · Cited by 4 · see citing works
Yilmaz, B. D., Schwartz, K. M., Chan, M., Cedars, M. I., Çakmak, H., & Huang, D. (2025) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-025-03614-2 · Cited by 4 · see citing works
Decoding the multifactorial etiology of chronic endometritis
You, G., Yu, S., Liu, M., Diao, L., Lian, R., & Li, Y. (2025) · Placenta · doi:10.1016/j.placenta.2025.09.007 · Cited by 4 · see citing works
Poli‐Neto, O. B., Meola, J., & Silva, J. C. R. E. (2020) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0040-1713807 · Cited by 4 · see citing works
A Standard Pipeline for Analyzing the Endometrial Microbiome
Torres, M. D. M. G., & Lanza, D. C. F. (2024) · Reproductive Sciences · doi:10.1007/s43032-024-01557-0 · Cited by 6 · see citing works
Current status of endometrial dysfunction in the combined pathology of uterus: a literature review
Burova, N. A., Жаркин, Н. А., Murzina, O. Y., & Shatilova, Y. A. (2021) · V F Snegirev Archives of Obstetrics and Gynecology · doi:10.17816/2313-8726-2021-8-4-191-198 · Cited by 3 · see citing works
Aslan, B., Ersöz, C. C., Şükür, Y. E., Özmen, B., Sönmezer, M., Berker, B., Aytaç, R., & Atabekoğlu, C. S. (2025) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12681 · Cited by 3 · see citing works
Analysis of the Predictive Factors for Chronic Endometritis Recurrence in Infertile Women
Shiobara, K., Kuroda, K., Ishiyama, S., Nakao, K., Moriyama, A., Horikawa, T., Takamizawa, S., Nojiri, S., Nakagawa, K., & Sugiyama, R. (2024) · American Journal of Reproductive Immunology · doi:10.1111/aji.70002 · Cited by 3 · see citing works
Analysis of the risk factors of chronic endometritis in infertile women
Zhang, C., Meng, S., Tu, X., Wang, Y., Meng, D., Zhang, W., Li, Y., & He, W. (2025) · BMC Women s Health · doi:10.1186/s12905-025-03868-z · Cited by 3 · see citing works
Surcel, M., Neamtiu, I. A., Mureșan, D., Goidescu, I. G., Staicu, A., Marta, M. M., Nemeti, G. I., Harsa, R., Doroftei, B., Căpîlna, M. E., et al. (2023) · Diagnostics · doi:10.3390/diagnostics13193048 · Cited by 3 · see citing works
Clinical Management of Infertility Associated with Endometriosis
Sean, S., Tran, C., Ou, P., Ouk, C., Pirtea, P., & de Ziegler, D. (2024) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2024.102409 · Cited by 4 · see citing works
Elevated basophil count is associated with increased odds of endometriosis
Feng, Q., Shigesi, N., Guan, J., Rahmioğlu, N., Bafadhel, M., Paddon, K., Hubbard, C., Zondervan, K. T., Becker, C. M., & Hellner, K. (2024) · Reproduction and Fertility · doi:10.1530/raf-23-0090 · Cited by 3 · see citing works
Risk of Surgical Site Infection After Clean Laparoscopy for Endometriosis
Stewart, K. A., Ubl, D. S., Habermann, E. B., Khan, Z., Burnett, T. L., & Cope, A. G. (2025) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2025.06.001 · Cited by 2 · see citing works
Millán, F. P., Campo, M. C., Arroyo, J. A. D., Roig, M. C., Bartolomé, E. M., Haimovich, S., de la Blanca, E. P., Ziarrusta, G. B., Águeda, J. M. P., Zambrano, J. L. A., et al. (2026) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2026.02.021 · Cited by 2 · see citing works
Sklyarova, V., Shatylovich, K., Filipyuk, A., Sklyarov, P., & Chajkivskyj, R. (2020) · European Journal of Medical and Health Sciences · doi:10.24018/ejmed.2020.2.6.560 · Cited by 2 · see citing works
Gürgan, T., & Bektaş, G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-89907-9.00014-4 · Cited by 2 · see citing works
Features of vaginal microflora in patients with chronic endometriti
Lyzikova, Y. A. (2023) · Medical news of the North Caucasus · doi:10.14300/mnnc.2023.18011 · Cited by 2 · see citing works
Discussion issues in the treatment of chronic endometritis
Дикке, Г. Б. (2023) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2023-086 · Cited by 2 · see citing works
Sukhanov, A. A., Дикке, Г. Б., & Ивановна, К. И. (2023) · Russian Journal of Human Reproduction · doi:10.17116/repro20232903198 · Cited by 2 · see citing works
The psychometric properties test of the Malay version of the endometriosis health profile-30
Mansor, M. B., Chong, M. C., Chui, P. L., Hamdan, M., & Basha, M. A. M. K. (2023) · Saudi Medical Journal · doi:10.15537/smj.2023.44.9.20230228 · Cited by 2 · see citing works
Michelson, A. A., Ивановна, Т. М., Lazukina, M. V., Chistyakova, G. N., Ustyuzhanin, A. V., Вараксин, А. Н., Maslakova, T. A., & Даниловна, К. Е. (2023) · GYNECOLOGY · doi:10.26442/20795696.2023.3.202353 · Cited by 2 · see citing works
Endometriosis as an Infectious Disease: Association with Chronic Endometritis
Kitaya, K., Mihara, T., & Mihara, M. (2023) · Clinical and Experimental Obstetrics & Gynecology · doi:10.31083/j.ceog5001010 · Cited by 1 · see citing works
Wu, X., Shufang, N. I. U., & Zhao, T. (2023) · Journal of Zhejiang University (Medical Sciences) · doi:10.3724/zdxbyxb-2022-0513 · Cited by 1 · see citing works
- Authors
- Cicinelli, E., Trojano, G., Mastromauro, M., Vimercati, A., Marinaccio, M., Mitola, P. C., Resta, L., & de Ziegler, D.
- Affiliations
- University of Bari Aldo Moro (IT)
- Corresponding author
- Cicinelli, Ettore
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 108
- Issue
- 2
- Pages
- 289-295.e1
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2626018945
- Cited by
- 147
- References
- 44
- Citations by year
- 2026: 16 · 2025: 19 · 2024: 17 · 2023: 22 · 2022: 19 · 2021: 15 · 2020: 17 · 2019: 12 · 2018: 10
- FWCI
- 12.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion, cc-by-nc-nd)
- INFM-OAR (INFN Catania) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Keywords
- chronic endometritis, endometriosis, CD138+ cells, syndecan-1, hysterectomy, parity, abnormal uterine bleeding, endometritis, etiopathogenesis
- MeSH terms
- Adult, Chronic Disease, Endometriosis, Endometritis, Female, Humans, Hysterectomy, Italy, Retrospective Studies, Risk Factors, Uterine Hemorrhage, Comorbidity, Causality, Prevalence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
