What if deep endometriotic nodules and uterine adenomyosis were actually two forms of the same disease?

Pathogenesis of uterine adenomyosis, invagination or metaplasia?

García-Solares, J., Donnez, J., Donnez, O., & Dolmans, M.-M. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.12.030 · Cited by 339 · see citing works

Role of transvaginal sonography and magnetic resonance imaging in the diagnosis of uterine adenomyosis

Bazot, M., & Daraï, É. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.01.024 · Cited by 332 · see citing works

Relationship between the magnetic resonance imaging appearance of adenomyosis and endometriosis phenotypes

Chapron, C., Tosti, C., Marcellin, L., Bourdon, M., Lafay-Pillet, M.-C., Millischer, A.-E., Streuli, I., Borghese, B., Petraglia, F., & Santulli, P. (2017) · Human Reproduction · doi:10.1093/humrep/dex088 · Cited by 294 · see citing works

Peritoneal endometriosis and “endometriotic” nodules of the rectovaginal septum are two different entities

Donnez, J., Nisolle, M., Smoes, P., Gillet, N., Beguin, S., & Casanas-Roux, F. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58501-x · Cited by 147 · see citing works

Gynecologic and obstetric surgery

Nichols, D. H. (1993) · Mosby eBooks · Cited by 118 · see citing works

Epidemiology of Adenomyosis

Upson, K., & Missmer, S. A. (2020) · Seminars in Reproductive Medicine · doi:10.1055/s-0040-1718920 · Cited by 254 · see citing works

Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review

Donnez, J., & Dolmans, M.-M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10051085 · Cited by 182 · see citing works

Pathology and Pathogenesis of Adenomyosis

Antero, M. F., Ayhan, A., Segars, J. H., & Shih, I. (2020) · Seminars in Reproductive Medicine · doi:10.1055/s-0040-1718922 · Cited by 85 · see citing works

Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology

Guo, S. (2022) · Reproduction · doi:10.1530/rep-22-0224 · Cited by 79 · see citing works

Androgens, oestrogens and endometrium: a fine balance between perfection and pathology

Gibson, D. A., Simitsidellis, I., Collins, F., & Saunders, P. T. K. (2020) · Journal of Endocrinology · doi:10.1530/joe-20-0106 · Cited by 76 · see citing works

Origin and Pathogenic Mechanisms of Uterine Adenomyosis: What Is Known So Far

Stratopoulou, C. A., Donnez, J., & Dolmans, M. (2020) · Reproductive Sciences · doi:10.1007/s43032-020-00361-w · Cited by 69 · see citing works

Conservative management of uterine adenomyosis: medical vs. surgical approach

Stratopoulou, C. A., Donnez, J., & Dolmans, M.-M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10214878 · Cited by 62 · see citing works

Gonadotropin-releasing hormone antagonist (linzagolix): A new therapy for uterine adenomyosis

Donnez, O., & Donnez, J. (2020) · Fertility and Sterility · doi:10.1016/j.fertnstert.2020.04.017 · Cited by 58 · see citing works

Endometriosis and adenomyosis: Similarities and differences

Donnez, J., Stratopoulou, C. A., & Dolmans, M.-M. (2024) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2023.102432 · Cited by 57 · see citing works

Uterine Adenomyosis: From Disease Pathogenesis to a New Medical Approach Using GnRH Antagonists

Donnez, J., Stratopoulou, C. A., & Dolmans, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18199941 · Cited by 55 · see citing works

Exploring the challenges for a new classification of adenomyosis

Habiba, M. A., Gordts, S., Bazot, M., Brosens, I. A., & Benagiano, G. (2020) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2020.01.017 · Cited by 45 · see citing works

Ectopic Endometrium: The Pathologist’s Perspective

Camboni, A., & Marbaix, É. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010974 · Cited by 46 · see citing works

A critical review of recent advances in the diagnosis, classification, and management of uterine adenomyosis

Tan, J., Yong, P. J., & Bedaiwy, M. A. (2019) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000555 · Cited by 42 · see citing works

Endometriosis and Adenomyosis: From Pathogenesis to Follow-Up

Martire, F. G., Costantini, E., d’Abate, C., Schettini, G., Sorrenti, G., Centini, G., Zupi, E., & Lazzeri, L. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47050298 · Cited by 42 · see citing works

Conservative Management of Rectovaginal Deep Endometriosis: Shaving Should Be Considered as the Primary Surgical Approach in a High Majority of Cases

Donnez, O. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10215183 · Cited by 29 · see citing works

Deep endometriosis: The place of laparoscopic shaving

Donnez, O., & Donnez, J. (2021) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2020.05.006 · Cited by 28 · see citing works

MRI of Adenomyosis: Where Are We Today?

Zhang, M., Bazot, M., Tsatoumas, M., Munro, M. G., & Reinhold, C. (2022) · Canadian Association of Radiologists Journal · doi:10.1177/08465371221114197 · Cited by 28 · see citing works

Efficacy of the levonorgestrel-releasing intrauterine device is associated with different subtypes of adenomyosis: a retrospective study

Chen, S., Wang, J., Sun, W., Zhu, L., He, J., & Zhang, X. (2020) · Annals of Translational Medicine · doi:10.21037/atm-20-3420 · Cited by 27 · see citing works

Uterine Adenomyosis Treated by Linzagolix, an Oral Gonadotropin-Releasing Hormone Receptor Antagonist: A Pilot Study with a New ’Hit Hard First and then Maintain’ Regimen of Administration

Donnez, J., Donnez, O., Tourniaire, J., Brethous, M., Bestel, E., Garner, E. I. O., Charpentier, S., Humberstone, A., & Loumaye, E. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10245794 · Cited by 28 · see citing works

Identifying Common Pathogenic Features in Deep Endometriotic Nodules and Uterine Adenomyosis

Stratopoulou, C. A., Camboni, A., Donnez, J., & Dolmans, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10194585 · Cited by 27 · see citing works

Characterising the immune cell phenotype of ectopic adenomyosis lesions compared with eutopic endometrium: A systematic review

Maclean, A., Barzilova, V., Patel, S., Bates, F., & Hapangama, D. K. (2023) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2023.103925 · Cited by 24 · see citing works

Are Adenomyosis and Endometriosis Phenotypes of the Same Disease Process?

Habiba, M. A., Guo, S., & Benagiano, G. (2023) · Biomolecules · doi:10.3390/biom14010032 · Cited by 23 · see citing works

Establishment of Adenomyosis Organoids as a Preclinical Model to Study Infertility

Juárez‐Barber, E., Francés‐Herrero, E., Corachán, A., Vidal, C., Gilés, J., Alamá, P., Faus, A., Pellicer, A., Cervelló, I., & Ferrero, H. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12020219 · Cited by 22 · see citing works

Unveiling the Pathogenesis of Adenomyosis through Animal Models

Wang, X., Benagiano, G., Liu, X., & Guo, S. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11061744 · Cited by 19 · see citing works

Are lower levels of apoptosis and autophagy behind adenomyotic lesion survival?

d'Argent, M., Stratopoulou, C. A., Cussac, S., Camboni, A., Jadoul, P., Donnez, J., & Dolmans, M. (2023) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2023.06.003 · Cited by 16 · see citing works

Overview of crosstalk between stromal and epithelial cells in the pathogenesis of adenomyosis and shared features with deep endometriotic nodules

Zipponi, M., Cacciottola, L., & Dolmans, M. (2024) · Human Reproduction · doi:10.1093/humrep/deae116 · Cited by 14 · see citing works

Minimally invasive adenomyomectomy via a laparoscopic-assisted approach compared to a laparoscopic or laparotomic approach

Ahn, J., You, S.-G., Go, E. B., Lee, S., Kim, J. S., Cho, H. J., & Roh, H. J. (2021) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2021.09.010 · Cited by 12 · see citing works

Deep Infiltrating Endometriosis and Adenomyosis: Implications on Pregnancy and Outcome

Gruber, T. M., Ortlieb, L., Henrich, W., & Mechsner, S. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010157 · Cited by 11 · see citing works

The role of imaging as a guide to the surgical treatment of endometriosis

Burnett, T. L., Feldman, M., & Huang, J. Q. (2020) · Abdominal Radiology · doi:10.1007/s00261-019-02399-0 · Cited by 11 · see citing works

Spatiotemporal expression pattern of Progesterone Receptor Component (PGRMC) 1 in endometrium from patients with or without endometriosis or adenomyosis

Thieffry, C., Wynendaele, M. V., Samain, L., Tyteca, D., Pierreux, C. E., Marbaix, É., & Henriet, P. (2022) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2022.106153 · Cited by 9 · see citing works

Diagnostic gene biomarkers for predicting immune infiltration in endometriosis

Xie, C., Lu, C., Liu, Y., & Liu, Z. (2022) · BMC Women s Health · doi:10.1186/s12905-022-01765-3 · Cited by 9 · see citing works

Adenomyosis Localized in Both the Anterior and Posterior Myometrium Is Associated with Deep Rectal Endometriosis: A Retrospective Study

Schawlochow, K., Samartzis, N., Burla, L., Eberhard, M., Kalaitzopoulos, D. R., & Leeners, B. (2024) · Biomedicines · doi:10.3390/biomedicines12112527 · Cited by 8 · see citing works

Laparoscopic “Shaving” for Infiltrative External Adenomyosis of Bowel Muscularis and Concomitant Deep Infiltrating Endometriosis

Wu, K.-L., Chua, P. T., & Lee, C.-L. (2021) · Gynecology and Minimally Invasive Therapy · doi:10.4103/gmit.gmit_27_20 · Cited by 5 · see citing works

Phenotypic heterogeneity in adenomyosis: internal and external subtypes

Liang, Y., Zhu, M., Sun, F., Liu, X., Liu, J., & Zhang, J. (2025) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-025-08166-5 · Cited by 3 · see citing works

Drug development for adenomyosis based on pathophysiology

Guo, S. (2025) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.16322 · Cited by 4 · see citing works

The role of mitochondrial DNA copy number in female infertility: a bidirectional two-sample Mendelian randomization study

Wan, X., Lai, X., Huang, M., Yu, M., Ding, T., Huang, Z., Zhang, Z., Wu, X., & Tan, J. (2024) · Gynecological Endocrinology · doi:10.1080/09513590.2024.2444380 · Cited by 3 · see citing works

MRI of Adenomyosis: Where Are We Today?

Zhang, M., Bazot, M., Tsatoumas, M., Munro, M. G., & Reinhold, C. (2022) · Current Obstetrics and Gynecology Reports · doi:10.1007/s13669-022-00342-7 · Cited by 2 · see citing works

Endometriosis and Adenomyosis

Vannuccini, S., Aslan, B., & Petraglia, F. (2024) · ISGE series · doi:10.1007/978-3-031-55300-4_9 · Cited by 2 · see citing works

“Call me by my true names”. The utopian search for endometriosis and adenomyosis terminology devoid of ambiguous pathogenic meaning: Just an illusion?

Vercellini, P., & Somigliana, E. (2023) · Journal of Endometriosis and Uterine Disorders · doi:10.1016/j.jeud.2023.100020 · Cited by 2 · see citing works

Pathogenesis of Endometriosis: Theories of the Cells of Origin and Methods of Dissemination

Martin, D. C. (2022) · Springer eBooks · doi:10.1007/978-3-030-97236-3_3

Differences clinical characteristics and factors in intrinsic and extrinsic adenomyosisPreprint

Liang, Y., Shi, W., Sun, F., Zhu, M., Liu, Y., & Zhang, J. (2023) · Research Square · doi:10.21203/rs.3.rs-2752816/v1

Extrauterine adenomyomas managed by laparoscopic excision: Three case reports with different theories of origin

Nagy, C., Papp, S., Eldin, N. A., & El-Maadawy, S. M. (2023) · International Journal of Case Reports and Images · doi:10.5348/101409z01cn2023cr

Society of Endometriosis and Uterine Disorders forum: adenomyosis today, Paris, France, December 12, 2023

Catherino, W. H., As‐Sanie, S., Cozzolino, M., Marcellin, L., Missmer, S. A., Stewart, E. A., den Bosch, T. V., Chapron, C., & Petraglia, F. (2024) · F&S Science · doi:10.1016/j.xfss.2024.06.006

Mediocentral Compartment: Uterus: External Adenomyosis

Forstner, R. (2025) · Springer eBooks · doi:10.1007/978-3-031-82750-1_8

MicroRNAs associated with adenomyosis promote endometrial epithelial cell migration via MMP-2 and MMP-9 upregulation

Zipponi, M., Camboni, A., Mamillapalli, R., Taylor, H. S., & Dolmans, M. (2025) · Biology of Reproduction · doi:10.1093/biolre/ioaf231

The assessment of association between endometrioma size and other endometriosis compartments according to #ENZIAN classification

Piriyev, E., Namazov, A., Magalov, I., Huseynova, F., Liberty, G., Gemer, O., Schiermeier, S., Römer, T., & Keckstein, J. (2026) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-026-08354-x

Epidemiology of endometriosis and adenomyosis

Upson, K., Missmer, S. A., Tellum, T., Harris, H. R., & As‐Sanie, S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-45863-7.00031-7

Association of immune-inflammatory indices with focal adenomyosis of the outer myometrium in deep infiltrating endometriosis

Tian, Y., Fang, X., Zhang, G., Gao, Y., Chang, L., Tian, X., & He, Y. (2026) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2026.104941

Role of oral gonadotropin-releasing hormone antagonists in the management of uterine adenomyosis: a narrative review

Donnez, J., Donnez, O., Taylor, H. S., Petraglia, F., Horne, A. W., Becker, C. M., Renner, S. P., Rius, M., Bestel, E., Stratopoulou, C. A., et al. (2026) · Reproduction and Fertility · doi:10.1530/raf-26-0075

Endometriosis and adenomyosis: Similarities and differences

Donnez, J., Stratopoulou, C. A., & Dolmans, M.-M. (2024) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2023.102432 · Cited by 57 · see citing works

Identifying Common Pathogenic Features in Deep Endometriotic Nodules and Uterine Adenomyosis

Stratopoulou, C. A., Camboni, A., Donnez, J., & Dolmans, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10194585 · Cited by 27 · see citing works

Patients with adenomyosis are more likely to have deep endometriosis

Gonzales, M., Matos, L. A., Gonçalves, M. O., Blasbalg, R., Dias, J., Podgaec, S., Baracat, E. C., & Abrão, M. S. (2012) · Gynecological Surgery · doi:10.1007/s10397-012-0746-4 · Cited by 25 · see citing works

Endometriosis and adenomyosis

Lachelin, G. C. L. (1991) · Elsevier eBooks · doi:10.1016/b978-0-7506-1171-8.50013-1

Relationship between adenomyosis and endometriosis; Different phenotypes of a single disease?

Maruyama, S., Imanaka, S., Nagayasu, M., Kimura, M., & Kobayashi, H. (2020) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2020.08.019 · Cited by 67 · see citing works