Quantification of polyphenols and ergothioneine in cultivated mushrooms and correlation to total antioxidant capacity
Abstract
Agaricus bisporus, Lentinula edodes, Pleurotus ostreatus, Pleurotus eryngii and Grifola frondosa were analyzed for antioxidant capacity, as measured by oxygen radical absorbance capacity (lipophilic and hydrophilic) (ORACtotal), hydroxyl radical averting capacity (HORAC), peroxynitrite radical averting capacity (NORAC), superoxide radical averting capacity (SORAC) assays, Folin-Ciocalteu reagent and ergothioneine (ERG) content. ORACtotalvalues ranged from 39 to 138 μmol of Trolox equivalents (TE)/g dry weight (dw). HORAC values ranged from 3.0 to 13.6 μmol of caffeic acid equivalents/g dw. NORAC values ranged from 2.0 to 9.0 μmol TE/g dw. SORAC values ranged from 0.37 to 2.6 kunit superoxide dismutate equivalents/g dw. Polyphenols ranged from 4.2 to 10.6 mg gallic acid equivalents/g dw. A. bisporus mushrooms, especially portabellas, had higher antioxidant capacity relative to the specialty mushrooms tested. ERG ranged from 0.21-2.6 mg/g dw with L. edodes, P. ostreatus, G. frondosa containing a statistically significant greater amount compared to A. bisporus. A good correlation was found between ORACtotal and polyphenols (R2 = 0.86).
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In mushrooms, ERG is typically the main antioxidant, and it may also inhibit tyrosinase.
“This also seems true of mushrooms(271,272), where ERG is typically the main antioxidant(273–275), and where it may also inhibit the oxidative enzyme tyrosinase(276).”
From The biology of ergothioneine, an antioxidant nutraceutical (2020) · cites this paper as [275]
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The biology of ergothioneine, an antioxidant nutraceutical
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BackgroundThe evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine
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- Authors
- DUBOST, N., OU, B., & BEELMAN, R.
- Affiliations
- Pennsylvania State University (US)
- Brunswick (United States) (US)
- Corresponding author
- DUBOST, N
- ORCID
- BEELMAN, R
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2007
- Volume
- 105
- Issue
- 2
- Pages
- 727-735
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W2031862180
- Cited by
- 365
- References
- 5
- Citations by year
- 2026: 13 · 2025: 23 · 2024: 24 · 2023: 20 · 2022: 24 · 2021: 36 · 2020: 21 · 2019: 13 · 2018: 16 · 2017: 22 · 2016: 27 · 2015: 20 · 2014: 17 · 2013: 26 · 2012: 21
- FWCI
- 6.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food Chemistry (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Fungal Biology and Applications
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food and Agricultural Sciences
- Keywords
- polyphenols, ergothioneine, antioxidant capacity, cultivated mushrooms, Agaricus bisporus, shiitake mushroom, Pleurotus ostreatus, Pleurotus eryngii, Grifola frondosa, ORAC, hydroxyl radical scavenging, superoxide radical scavenging, Folin-Ciocalteu assay
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