The DOI matches its Crossref record; 223 of the 223 references it cites were found in a registry or an index.
Microalgae as a Sustainable Source of Edible Proteins and Bioactive Peptides—Current Trends and Future Prospects
Abstract
The global demand for protein ingredients is continuously increasing owing to the growing population, rising incomes, increased urbanization, and aging population. Conventionally, animal-derived products (dairy, egg, and meat) satisfy the major dietary protein requirements of humans. With the global population set to reach 9.6 billion by 2050, there would be a huge deficit in meeting dietary protein requirements. Therefore, it is necessary to identify sustainable alternative protein sources that could complement high-quality animal proteins. In recent years, microalgae have been advocated as a potential industrial source of edible proteins owing to their wide and excellent ecological adaptation. Microalgae can grow in marginal areas utilizing non-potable wastewaters with high photosynthetic efficiency. Previously microalgae species such as Arthospira, and Chlorella have been used as single-cell proteins (SCP) with limited application in pharmaceutical industries. In recent years, the demand for innovative and sustainable functional ingredients for food applications has renewed the interest worldwide in microalgae proteins. The present review aims to provide a holistic view of various aspects related to the production and processing of edible proteins from microalgae biomass. A critical review of available literature on the nutritional quality, techno-functional properties, applications in food and feed sectors, and biological activities is presented. Further, challenges associated with each stage of processing are discussed. From the literature review, it can be summarized that microalgae proteins are comparable to reference proteins both in terms of amino acid (AA) quality and techno-functional properties. However recalcitrant cell wall poses a challenge in digestibility and effective utilization of the microalgae proteins. Further, poor sensory scores and palatability of microalgae biomass limit its applications in the food and feed sector. Novel applications of microalgae proteins include meat analogues, emulsifying agents, and bioactive peptides. Development of low-cost cultivation strategies, wet biomass-based downstream processing along with the bio-refinery approach of complete biomass volarization would enhance the sustainability quotient for human food applications.
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“Microalgae are a rich source of carbohydrates, proteins, fatty acids, enzymes, and dietary fibre [75].”
From Multi-Sensing Monitoring of the Microalgae Biomass Cultivation Systems for Biofuels and Added Value Products Synthesis—Challenges and Opportunities (2025) · cites this paper as [75]
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Cites
1 retracted
Koyande, A. K., Show, P.-L., Guo, R., Tang, B., Ogino, C., & Chang, J.-S. (2019) · Bioengineered · doi:10.1080/21655979.2019.1679697 · Cited by 182
RetractedChisti, Y. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.02.001 · Cited by 9,524
Brennan, L., & Owende, P. (2010) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2009.10.009 · Cited by 4,894
The State of World Fisheries and Aquaculture 2020
(2020) · doi:10.4060/ca9229en · Cited by 3,167
Micro-algae as a source of protein
Becker, E. W. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2006.11.002 · Cited by 2,311
Protein and amino acid requirements in human nutrition.
(2007) · PubMed · Cited by 2,234
Bioactive peptides: Production and functionality
Korhonen, H. J. T., & Pihlanto, A. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2005.10.012 · Cited by 1,822
Life-Cycle Assessment of Biodiesel Production from Microalgae
Lardon, L., Hélias, A., Sialve, B., Steyer, J.-P., & Bernard, O. (2009) · Environmental Science & Technology · doi:10.1021/es900705j · Cited by 1,528
‘Morphology, composition, production, processing and applications of Chlorella vulgaris: a review’.
Safi, C., Zebib, B., Merah, O., Pontalier, P.-Y., & Vaca-Garcia, C. (2014) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2014.04.007 · Cited by 1,127
Nutritional properties of microalgae for mariculture
Brown, M. R., Jeffrey, S. W., Volkman, J. K., & Dunstan, G. A. (1997) · Aquaculture · doi:10.1016/s0044-8486(96)01501-3 · Cited by 1,041
Research works printed but not linked: 10
- Aguero, 2017, Membrane processes for whey proteins separation and purification, A review. Current Organic Chemistry, 21, 1740
- Cho, 2004, Keeping quality and sensory properties of drinkable yoghurt with added Chlorella extract, Korean Journal of Food Nutrition, 17, 128
- European Food Safety Authority, Union List of Novel Food in Accordance with Regulation (EU) 2015/2283 (COMMISSION IMPLEMENTING REGULATION (EU) 2017/2470), Official Journal of European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32017R2470&qid=1638194717330&from=EN, accessed on November 2021.
- https://www.grandviewresearch.com/press-release/global-algae-protein-market.
- Jassby, A. in Algae and Human Affairs, ed(s). C.A. Lembi and J.R. Waaland, Phycological Society of America, Cambridge University Press, Cambridge, 1988, ch. 8, 181-204.
- Kulpys, 2009, Influence of cyanobacteria Arthrospira (Spirulina) platensis biomass additive towards the body condition of lactation cows and biochemical milk indexes, Agronomy Research, 7, 823
- Odum, E. P., & Barrett, G. W. (1971). Fundamentals of ecology (Vol. 3, p. 5). Philadelphia: Saunders.
- Saleh, 1987, Blue-green algae in bread manufacture. Blaugruene Algen bei der Brotherstellung), Getreide Mehl und Brot, 41, 19
- Sarker, 2020, Towards sustainable and ocean-friendly aquafeeds: Evaluating a fish-free feed for rainbow trout (Oncorhynchus mykiss) using three marine microalgae species, Elementa: Science of the Anthropocene, 8
- Vúkari, 1977, Reduction of nucleic acid content of SCP, Process biochemistry., 16, 17
Cited by
Sorted by citations
Parmar, P., Kumar, R., Neha, Y., & Srivatsan, V. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1073546 · Cited by 279
Self-citationPerez-Vazquez, A., Carpena, M., Barciela, P., Cassani, L., Simal‐Gándara, J., & Prieto, M. A. (2023) · Antioxidants · doi:10.3390/antiox12030612 · Cited by 134
Algae as a potential source of protein meat alternatives
Espinosa‐Ramírez, J., Mondragón, A. D. C., Rodríguez, J. A., Lorenzo, J. M., & Santos, E. M. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1254300 · Cited by 129
Hu, J., Meng, W., Su, Y., Qian, C., & Fu, W. (2023) · Frontiers in Marine Science · doi:10.3389/fmars.2023.1260709 · Cited by 124
Microalgae: potential novel protein for sustainable human nutrition
Williamson, E., Ross, I. L., Wall, B. T., & Hankamer, B. D. (2023) · Trends in Plant Science · doi:10.1016/j.tplants.2023.08.006 · Cited by 122
Metadata
- Authors
- Kumar, R., Hegde, A. S., Sharma, K., Parmar, P., & Srivatsan, V.
- Affiliations
- Institute of Himalayan Bioresource Technology (IN)
- Corresponding author
- Srivatsan, Vidyashankar
- Venue
- Food Research International
- Publisher
- Elsevier BV
- Published
- 2022-07
- Volume
- 157
- Pages
- 111338
- ISSN
- 0963-9969 (ISSN-L)
- OpenAlex
- W4280632959
- Cited by
- 209
- References
- 223
- Citations by year
- 2026: 53 · 2025: 63 · 2024: 54 · 2023: 34 · 2022: 5
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Food Research International (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Council of Scientific and Industrial Research, India (33/FTT/FTC/ANB/2020-TMD-IND_INT)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Keywords
- microalgal proteins, edible protein, bioactive peptides, microbial protein, alternative protein sources, Arthrospira, Chlorella, techno-functional properties, cell wall recalcitrance, digestibility, meat substitutes, emulsifiers, food and feed applications, biorefinery, downstream processing, sustainable protein production
- MeSH terms
- Animals, Chlorella, Dietary Proteins, Peptides, Biomass, Microalgae
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