Mitochondria and reactive oxygen species

“ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis”—a critical commentary

Zielonka, J., & Kalyanaraman, B. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.07.025 · Cited by 65

H2O2 generation in Saccharomyces cerevisiae respiratory pet mutants: effect of cytochrome c

de Barros, M. H. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00307-1 · Cited by 65

Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways

Milani, G., Jarmuszkiewicz, W., Sluse-Goffart, C. M., Schreiber, A. Z., Vercesi, A. E., & Sluse, F. E. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03060-5 · Cited by 65

Cytochrome c is released from coupled mitochondria of yeast en route to acetic acid‐induced programmed cell death and can work as an electron donor and a ROS scavenger

Giannattasio, S., Atlante, A., Antonacci, L., Guaragnella, N., Lattanzio, P., Passarella, S., & Marra, E. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.03.048 · Cited by 59

Activation of alternative oxidase and uncoupling protein lowers hydrogen peroxide formation in amoeba Acanthamoeba castellanii mitochondria

Czarna, M., & Jarmuszkiewicz, W. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.04.081 · Cited by 57

4-Hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production

Echtay, K. S., & Brand, M. D. (2007) · Redox Report · doi:10.1179/135100007x162158 · Cited by 55

The oxidation of phenylacetaldehyde by plant saps

Kenten, R. H. (1953) · Biochemical Journal · doi:10.1042/bj0550350 · Cited by 54

Redox properties of the adenoside triphosphate‐sensitive K+ channel in brain mitochondria

Fornazari, M., de Paula, J. G., Castilho, R. F., & Kowaltowski, A. J. (2008) · Journal of Neuroscience Research · doi:10.1002/jnr.21614 · Cited by 53

Increased aerobic metabolism is essential for the beneficial effects of caloric restriction on yeast life span

de Oliveira, G. A., Tahara, E. B., Gombert, A. K., de Barros, M. H., & Kowaltowski, A. J. (2008) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-008-9159-5 · Cited by 51

Oxidative stress in hypercholesterolemic LDL (low-density lipoprotein) receptor knockout mice is associated with low content of mitochondrial NADP-linked substrates and is partially reversed by citrate replacement

Paim, B. A., Velho, J. A., Castilho, R. F., Oliveira, H. C. F., & Vercesi, A. E. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.10.005 · Cited by 49

Effect of thyroid hormone on mitochondrial properties and oxidative stress in cells from patients with mtDNA defects

Menzies, K. J., Robinson, B. H., & Hood, D. A. (2008) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00415.2007 · Cited by 49

Respiration, oxidative phosphorylation, and uncoupling protein in Candida albicans

Cavalheiro, R. A., Fortes, F., Borecký, J., Faustinoni, V. C., & Schreiber, A. Z. (2004) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2004001000003 · Cited by 44

Plant Uncoupling Mitochondrial Protein Activity in Mitochondria Isolated from Tomatoes at Different Stages of Ripening

Costa, A. D. T., Nantes, I. L., Ježek, P., Leite, A., Arruda, P., & Vercesi, A. E. (1999) · Journal of Bioenergetics and Biomembranes · doi:10.1023/a:1005408809619 · Cited by 42

Stimulation of H2O2 generation by calcium in brain mitochondria respiring on α‐glycerophosphate

Tretter, L., Takacs, K., Kövér, K., & Ádám‐Vizi, V. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21405 · Cited by 42

Redox regulation of calcium release in skeletal and cardiac muscle

Hidalgo, C., Aracena-Parks, P., Sánchez, G., & Donoso, P. (2002) · Biological Research · doi:10.4067/s0716-97602002000200009 · Cited by 42

Repair of peroxynitrite damage to tubulin by the thioredoxin reductase system

Landino, L. M., Iwig, J. S., Kennett, K. L., & Moynihan, K. L. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.11.026 · Cited by 41

Opening of Mitochondrial K+ Channels Increases Ischemic ATP Levels by Preventing Hydrolysis

Belisle, E., & Kowaltowski, A. J. (2002) · Journal of Bioenergetics and Biomembranes · doi:10.1023/a:1020256502583 · Cited by 40

Hyperlipidemic Mice Present Enhanced Catabolism and Higher Mitochondrial ATP-Sensitive K+ Channel Activity

Alberici, L. C., Oliveira, H. C. F., Patrício, P. R., Kowaltowski, A. J., & Vercesi, A. E. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.07.021 · Cited by 40

On the formation of hydrogen peroxide and oxygen radicals in heart mitochondria.

Loschen, G., & Azzi, A. (1975) · PubMed · Cited by 40

Free radicals‐mediated damage in transmitochondrial cells harboring the T14487C mutation in the ND6 gene of mtDNA

Gonzalo, R., García‐Arumí, E., Lligé, D., Martí, R., Solano, A., Montoya, J., Arenas, J., & Andreu, A. L. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.11.034 · Cited by 38

Erratum: Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon doxide (Journal of Biological Chemistry (1999) 274 (10802-10806))

Bonini, M. G., Radí, R., Ferrer‐Sueta, G., et al. (1999) · Journal of Biological Chemistry · Cited by 37

Active oxygen species in the liver of rats submitted to chronic hypobaric hypoxia

Costa, L. E., Llesuy, S., & Boveris, A. (1993) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1993.264.6.c1395 · Cited by 36

H2O2 generation is decreased by calcium in isolated brain mitochondria

Komary, Z., Tretter, L., & Ádám‐Vizi, V. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2008.05.004 · Cited by 33

Liposome effect on the cytochrome c-catalyzed peroxidation of carbonyl substrates to triplet species

Nantes, I. L., Faljoni‐Alário, A., Vercesi, A. E., Santos, K. E., & Bechara, E. J. H. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00082-3 · Cited by 33

The Energy-Conserving and Energy-Dissipating Processes in Mitochondria Isolated from Wild Type and Nonripening Tomato Fruits During Development on the Plant

Almeida, A. M., Navet, R., Jarmuszkiewicz, W., Vercesi, A. E., Sluse‐Goffart, C. M., & Sluse, F. E. (2002) · Journal of Bioenergetics and Biomembranes · doi:10.1023/a:1022574327117 · Cited by 28

Protective Effect of Melatonin on Rotenone plus Ca 2+ -Induced Mitochondrial Oxidative Stress and PC12 Cell Death

de Sousa, S. C., & Castilho, R. F. (2005) · Antioxidants and Redox Signaling · doi:10.1089/ars.2005.7.1110 · Cited by 26

Redox Regulation of Cardiac Muscle Calcium Signaling

Morad, M., & Suzuki, Y. (2000) · Antioxidants and Redox Signaling · doi:10.1089/ars.2000.2.1-65 · Cited by 26

The relationship between the aging- and photo-dependent T414G mitochondrial DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts

Birket, M. J., Passos, J. F., von Zglinicki, T., & Birch-Machin, M. A. (2009) · Journal of Investigative Dermatology · doi:10.1038/jid.2008.373 · Cited by 24

CHEMILUMINESCENT DIPHENYLACETALDEHYDE OXIDATION BY MITOCHONDRIA IS PROMOTED BY CYTOCHROMES and LEADS TO OXIDATIVE INJURY OF THE ORGANELLE

Nantes, I. L., Cilento, G., Bechara, E. J. H., & Vercesi, A. E. (1995) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1995.tb02378.x · Cited by 23

Increased ROS generation and SOD activity in heteroplasmic tissues of transmitochondrial mice with A3243G mitochondrial DNA mutation

Li, J., Zhou, K., Meng, X., Wu, Q., Li, S., Liu, Y., & Wang, J. (2008) · Genetics and Molecular Research · doi:10.4238/vol7-4gmr480 · Cited by 22

Mitochondrial Permeability Transition Induced by Chemically Generated Singlet Oxygen

Cosso, R. G., Turim, J., Nantes, I. L., Almeida, A. M., Mascio, P. D., & Vercesi, A. E. (2002) · Journal of Bioenergetics and Biomembranes · doi:10.1023/a:1016075218162 · Cited by 17

Irradiated cationic mesoporphyrin induces larger damage to isolated rat liver mitochondria than the anionic form

Inada, N. M., Paniagua, C. E. D. S., Jorge, R. A., et al. (2006) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2006.10.025 · Cited by 13

Plant hormone ethylene is a Norrish type II product from enzymically generated triplet 1-butanal.

Knudsen, F. D. S., Čampa, A., Stefani, H. A., et al. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.410 · Cited by 12

Ischemic preconditioning enhances fatty acid-dependent mitochondrial uncoupling

Carreira, R., Miyamoto, S., Mascio, P. D., Gonçalves, L. M. M., Monteiro, P. F., Providência, L. A., & Kowaltowski, A. J. (2007) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-007-9093-y · Cited by 12

NADP redox state and mitochondrial Ca2+ efflux: a controversial issue.

Vercesi, A. E., & Pereira-da-Silva, L. (1984) · PubMed · Cited by 5

Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases

Bhattacharyya, A., Chattopadhyay, R., Mitra, S., & Crowe, S. E. (2014) · Physiological Reviews · doi:10.1152/physrev.00040.2012 · Cited by 2,484

Oxidative stress and autophagy: The clash between damage and metabolic needs

Filomeni, G., De Zio, D., & Cecconi, F. (2015) · Cell Death & Differentiation · doi:10.1038/cdd.2014.150 · Cited by 2,195

Mitochondrial dysfunction and oxidative stress in metabolic disorders - A step towards mitochondria based therapeutic strategies

Bhatti, J. S., Bhatti, G. K., & Reddy, P. H. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.11.010 · Cited by 1,655

Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement

Nolfi-Donegan, D., Braganza, A., & Shiva, S. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101674 · Cited by 1,488

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

Brand, M. D. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.04.001 · Cited by 1,063

Mitochondrial metabolism of reactive oxygen species

Andreyev, A. Y., Kushnareva, Y. E., & Starkov, A. A. (2005) · Biochemistry (Moscow) · doi:10.1007/s10541-005-0102-7 · Cited by 1,336

Reactive Oxygen Species and Oxidative Stress in Obesity—Recent Findings and Empirical Approaches

McMurray, F., Patten, D. A., & Harper, M. (2016) · Obesity · doi:10.1002/oby.21654 · Cited by 253

The role of mitochondria in reactive oxygen species metabolism and signaling

Starkov, A. A. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1427.015 · Cited by 846

Gold-induced reactive oxygen species (ROS) do not mediate suppression of monocytic mitochondrial or secretory function

Omata, Y., Lewis, J. B., Lockwood, P. E., Tseng, W., Messer, R. L. W., Bouillaguet, S., & Wataha, J. C. (2005) · Toxicology in Vitro · doi:10.1016/j.tiv.2005.11.001 · Cited by 14

Autophagy is required during cycling hypoxia to lower production of reactive oxygen species

Rouschop, K. M. A., Ramaekers, C. H. M. A., Schaaf, M. B. E., Keulers, T. G., Savelkouls, K. G. M., Lambin, P., Koritzinsky, M., & Wouters, B. G. (2009) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2009.06.029 · Cited by 145