NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., & Wang, X. (1997) · Cell · doi:10.1016/s0092-8674(00)80434-1 · Cited by 7,289

A role for mitochondria in nlrp3 inflammasome activation

Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature · doi:10.1038/nature09663 · Cited by 5,602

Microglia: a sensor for pathological events in the CNS

Kreutzberg, G. W. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10049-7 · Cited by 4,396

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Block, M. L., Zecca, L., & Hong, J.-S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2038 · Cited by 4,110

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Betarbet, R. S., Sherer, T., MacKenzie, G. M., Garcia‐Osuna, M., Panov, A. V., & Greenamyre, J. T. (2000) · Nature Neuroscience · doi:10.1038/81834 · Cited by 3,770

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

Bauernfeind, F. G., Horvath, G. L., Stutz, A., Alnemri, E. S., MacDonald, K. L., Speert, D. P., Fernandes‐Alnemri, T., Wu, J., Monks, B. G., Fitzgerald, K. A., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901363 · Cited by 3,087

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Hornung, V., Bauernfeind, F., Halle, A., Samstad, E. O., Kono, H., Rock, K. L., Fitzgerald, K. A., & Latz, E. (2008) · Nature Immunology · doi:10.1038/ni.1631 · Cited by 3,065

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Nakahira, K., Haspel, J. A., Rathinam, V. A. K., Lee, S.-J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., et al. (2011) · Nature Immunology · doi:10.1038/ni.1980 · Cited by 3,049

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

Heneka, M. T., Kummer, M. P., Stutz, A., Delekate, A., Schwartz, S., Vieira-Saecker, A., Griep, A., Axt, D., Remus, A., Tzeng, T.-C., et al. (2013) · Nature · doi:10.1038/nature11729 · Cited by 2,898

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Zhou, R., Tardivel, A., Thorens, B., Choi, I., & Tschopp, J. (2010) · Nature Immunology · doi:10.1038/ni.1831 · Cited by 2,708

Targeting Glial Mitochondrial Function for Protection from Cerebral Ischemia: Relevance, Mechanisms, and the Role of MicroRNAs

Li, L., & Stary, C. M. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/6032306 · Cited by 27

Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor

Nam, S. M., Choi, J. H., Choi, S.-H., Cho, H., Cho, Y., Rhim, H., Kim, H., Cho, I., Kim, D.-G., & Nah, S.-Y. (2020) · Journal of Ginseng Research · doi:10.1016/j.jgr.2020.04.002 · Cited by 26

Significance of protein kinase C in the neuropsychotoxicity induced by methamphetamine-like psychostimulants

Shin, E., Dang, D.-K., Hwang, Y. G., Tran, H., Sharma, N., Jeong, J. H., Jang, C., Nah, S.-Y., Nabeshima, T., Yoneda, Y., et al. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.01.014 · Cited by 26

Post-COVID-19 Parkinsonism and Parkinson’s Disease Pathogenesis: The Exosomal Cargo Hypothesis

Mysiris, D. S., Vavougios, G. D., Karamichali, E., Papoutsopoulou, S., Stavrou, V. T., Papayianni, E., Boutlas, S., Mavridis, T., Foka, P., Zarogiannis, S. G., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179739 · Cited by 25

Arterial stiffness induced by carotid calcification leads to cerebral gliosis mediated by oxidative stress

Sadekova, N., Iulita, M. F., Vallerand, D., Muhire, G., Bourmoum, M., Claing, A., & Girouard, H. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001557 · Cited by 25

Revisiting the critical roles of reactive microglia in traumatic brain injury

Zhao, J., Zhou, Y., Zhou, C.-W., Zhan, K., Yang, M., Wen, M., & Zhu, L. (2025) · International Journal of Surgery · doi:10.1097/js9.0000000000002420 · Cited by 30

Oral administration of carvacrol/β-cyclodextrin complex protects against 6-hydroxydopamine-induced dopaminergic denervation

Ribeiro, C. T., Gasparotto, J., Petiz, L. L., Brum, P. O., Peixoto, D. O., Kunzler, A., da Rosa, H. T., Bortolin, R. C., Almeida, R. F., Quintans‐Júnior, L. J., et al. (2019) · Neurochemistry International · doi:10.1016/j.neuint.2019.02.021 · Cited by 25

Repurposing of Tetracyclines for COVID-19 Neurological and Neuropsychiatric Manifestations: A Valid Option to Control SARS-CoV-2-Associated Neuroinflammation?

Filho, A. J. M. C., Gonçalves, F., Mottin, M., Andrade, C. H., Fonseca, S. N. S., & Macêdo, D. S. (2021) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-021-09986-3 · Cited by 25

Role of Oxidative Stress and Neuroinflammation in the Etiology of Alzheimer’s Disease: Therapeutic Options

Weinstock, M. (2025) · Antioxidants · doi:10.3390/antiox14070769 · Cited by 25

The Effect of C-Phycocyanin on Microglia Activation Is Mediated by Toll-like Receptor 4

Piovan, A., Filippini, R., Argentini, C., Moro, S., Giusti, P., & Zusso, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031440 · Cited by 23

Extracellular Mitochondria Activate Microglia and Contribute to Neuroinflammation in Traumatic Brain Injury

Zhang, C., Liu, C., Li, F., Zheng, M.-T., Liu, Y., Li, L., Yang, H., Zhang, S., Wang, C., Rong, H., et al. (2022) · Neurotoxicity Research · doi:10.1007/s12640-022-00566-8 · Cited by 23

Rice Germ Ameliorated Chronic Unpredictable Mild Stress-Induced Depressive-like Behavior by Reducing Neuroinflammation

Batsukh, S., Oh, S., Rheu, K.-M., Lee, B.-J., Park, C. H., Son, K. H., & Byun, K. (2022) · Nutrients · doi:10.3390/nu14245382 · Cited by 25

Role of protein kinase Cδ in dopaminergic neurotoxic events

Shin, E., Hwang, Y. G., Sharma, N., Tran, H., Dang, D.-K., Jang, C., Jeong, J. H., Nah, S.-Y., Nabeshima, T., & Kim, H. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.09.005 · Cited by 23

Disturbance of redox homeostasis as a contributing underlying pathomechanism of brain and liver alterations in 3‐hydroxy‐3‐methylglutaryl‐CoA lyase deficiency

Leipnitz, G., Vargas, C. R., & Wajner, M. (2015) · Journal of Inherited Metabolic Disease · doi:10.1007/s10545-015-9863-3 · Cited by 23

Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer’s disease

Xia, Z., Peng, W., Cheng, S., Zhong, B., Sheng, C., Zhang, C., Gong, W., Cheng, S., Li, J., & Wang, Z. (2017) · Oncotarget · doi:10.18632/oncotarget.17337 · Cited by 23

Mitochondrial immunometabolism in sepsis: orchestrating macrophage polarization and dysfunction

Yang, K., Zhao, Q., Sun, Y., Li, L., & Han, X. (2025) · European journal of medical research · doi:10.1186/s40001-025-03590-4 · Cited by 28

Total saponin of Dioscorea�collettii attenuates MSU crystal‑induced inflammation via inhibiting the activation of the NALP3 inflammasome and caspase‑1 in THP‑1 macrophages

Wang, L., Zhu, L.-R., Duan, C., Li, L., & Chen, G. (2020) · Molecular Medicine Reports · doi:10.3892/mmr.2020.11035 · Cited by 21

The P2X7 Receptor Involved in gp120-Induced Cell Injury in BV2 Microglia

Chen, Q., Wu, H., Qin, S., Liu, C., Chen, Y., Yang, Y., & Xu, C. (2016) · Inflammation · doi:10.1007/s10753-016-0417-0 · Cited by 21

Insulin treatment protects the brain against neuroinflammation by reducing cerebral cytokines and modulating mitochondrial function

Canteiro, P. B., Antero, D. C., Tramontin, N. D. S., Simon, K. U., Mendes, C., Corrêa, M. E. A. B., Silveira, P. C. L., & Muller, A. P. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.04.011 · Cited by 21

Potential of omega-3 and conjugated fatty acids to control microglia inflammatory imbalance elicited by obesogenic nutrients

Salsinha, A. S., Socodato, R., Rodrigues, A. C., Vale-Silva, R. S., Relvas, J. B., Pintado, M., & Rodríguez-Alcalá, L. M. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2023.159331 · Cited by 20

The A53T Mutation in α-Synuclein Enhances Proinflammatory Activation in Human Microglia Upon Inflammatory Stimulus

Krzisch, M., Yuan, B., Chen, W., Osaki, T., Fu, D., Garrett-Engele, C. M., Svoboda, D. S., Andrykovich, K. R., Gallagher, M. D., Sur, M., et al. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.07.011 · Cited by 20

Effects of naringin on learning and memory dysfunction induced by gp120 in rats

Qin, S., Chen, Q., Wu, H., Liu, C., Hu, J., Zhang, D., & Xu, C. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.04.020 · Cited by 20

The Interplay of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation in Autism Spectrum Disorder: Behavioral Implications and Therapeutic Strategies

Akhtar, A., & Rahaman, S. B. (2025) · Brain Sciences · doi:10.3390/brainsci15080853 · Cited by 21

Imatinib-induced hepatotoxicity via oxidative stress and activation of NLRP3 inflammasome: an in vitro and in vivo study

Huang, F., Fang, W., Cheng, Z., Shen, Y., Wang, D., Wang, Y., & Sun, L. (2022) · Archives of Toxicology · doi:10.1007/s00204-022-03245-x · Cited by 18

Hydrogen attenuates postoperative pain through Trx1/ASK1/MMP9 signaling pathway

Li, J., Ruan, S., Jia, J., Li, Q., Jia, R., Wan, L., Yang, X., Teng, P., Peng, Q., Shi, Y., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-022-02670-0 · Cited by 18

Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice

Sripetchwandee, J., Khamseekaew, J., Svasti, S., Srichairatanakool, S., Fucharoen, S., Chattipakorn, N., & Chattipakorn, S. C. (2019) · Life Sciences · doi:10.1016/j.lfs.2019.116878 · Cited by 18

The oxidatively damaged DNA and amyloid-β oligomer hypothesis of Alzheimer's disease

Sanders, O. D., Rajagopal, L., & Rajagopal, J. A. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.08.019 · Cited by 18

Prion protein N1 cleavage peptides stimulate microglial interaction with surrounding cells

Carroll, J. A., Groveman, B. R., Williams, K., Moore, R. A., Race, B., & Haigh, C. L. (2020) · Scientific Reports · doi:10.1038/s41598-020-63472-z · Cited by 19

The anti-asthmatic drug, montelukast, modifies the neurogenic potential in the young healthy and irradiated brain

Eriksson, Y., Boström, M., Sandelius, Å., Blennow, K., Zetterberg, H., Kuhn, H. G., & Kalm, M. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0783-7 · Cited by 16

The importance of controlling in vitro oxygen tension to accurately model in vivo neurophysiology

Bordt, E. A. (2017) · NeuroToxicology · doi:10.1016/j.neuro.2017.10.008 · Cited by 15

Gestational stress decreases postpartum mitochondrial respiration in the prefrontal cortex of female rats

Gorman‐Sandler, E., Robertson, B., Crawford, J., Wood, G., Ramesh, A., Arishe, O. O., Webb, R. C., & Hollis, F. (2023) · Neurobiology of Stress · doi:10.1016/j.ynstr.2023.100563 · Cited by 16

Possible Implications of Obesity-Primed Microglia that Could Contribute to Stroke-Associated Damage

Carreto, R. J. R., Rodríguez-Cortés, Y. M., Guerrero, H. T., & Chavarría, A. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01329-5 · Cited by 15

The Pathophysiological Underpinnings of Gamma-Band Alterations in Psychiatric Disorders

Palmisano, A., Pandit, S., Smeralda, C. L., Demchenko, I., Rossi, S., Battelli, L., Rivolta, D., Bhat, V., & Santarnecchi, E. (2024) · Life · doi:10.3390/life14050578 · Cited by 17

KCHO-1, a novel herbal anti-inflammatory compound, attenuates oxidative stress in an animal model of amyotrophic lateral sclerosis

Kook, M. G., Choi, S. W., Seo, Y., Kim, D. W., Song, B. K., Son, I., Kim, S., & Kang, K. (2017) · Journal of Veterinary Science · doi:10.4142/jvs.2017.18.4.487 · Cited by 15

Investigation of the Effects of a Novel NOX2 Inhibitor, GLX7013170, against Glutamate Excitotoxicity and Diabetes Insults in the Retina

Dionysopoulou, S., Wikström, P., Walum, E., Georgakis, S., & Thermos, K. (2024) · Pharmaceuticals · doi:10.3390/ph17030393 · Cited by 13

Extracellular Vesicles Cargo in Modulating Microglia Functional Responses

Torre, M. E. L., Panaro, M. A., Ruggiero, M., Polito, R., Cianciulli, A., Filannino, F. M., Lofrumento, D. D., Antonucci, L., Benameur, T., Monda, V., et al. (2022) · Biology · doi:10.3390/biology11101426 · Cited by 15

Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells

Lucotte, B., Tajhizi, M., Alkhatib, D., Samuelsson, E., Wiehager, B., Schedin‐Weiss, S., Sundström, E., Winblad, B. G., Tjernberg, L. O., & Behbahani, H. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8906-3 · Cited by 13

Effects of NADPH Oxidase Inhibitors and Mitochondria-Targeted Antioxidants on Amyloid β1-42-Induced Neuronal Deaths in Mouse Mixed Cortical Cultures

Hwang, S., & Kim, J.-K. (2018) · Chonnam Medical Journal · doi:10.4068/cmj.2018.54.3.159 · Cited by 13

Alpha-Synuclein-induced DNA Methylation and Gene Expression in Microglia

McGregor, B. A., Schommer, J., Guo, K., Raihan, M. O., Ghribi, O., Hur, J., & Porter, J. E. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.05.027 · Cited by 13

Thioredoxin-interacting protein (TXNIP) inhibition promotes retinal ganglion cell survival and facilitates M1-like microglial transformation via the PI3K/Akt pathway in glaucoma

Chen, J., Zhong, H., Shen, B., Yu, H., Zhang, Y., Han, R., Huang, P., Huang, S., & Zhong, Y. (2024) · Molecular Medicine · doi:10.1186/s10020-024-01058-5 · Cited by 12

Betulin isolated from Pyrola incarnata Fisch. inhibited lipopolysaccharide (LPS)-induced neuroinflammation with the guidance of computer-aided drug design

Liu, Q., Liu, J., Mei, J., Li, S.-J., Shi, L., Lin, Z.-H., Xie, B.-Y., Sun, W., Wang, Z., Yang, X., et al. (2020) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2020.127193 · Cited by 12

Mitophagy–NLRP3 Inflammasome Crosstalk in Parkinson’s Disease: Pathogenic Mechanisms and Emerging Therapeutic Strategies

Ahmed, S., Pasam, T., & Afreen, F. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27010486 · Cited by 12

Multi-omics analysis reveals GAPDH posttranscriptional regulation of IFN-γ and PHGDH as a metabolic checkpoint of microglia polarization

Yang, S., Yuan, Z., Zhu, Y., Liang, C., Chen, Z., Zhang, J., & Leng, L. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.01.009 · Cited by 11

TLR4 induced TRPM2 mediated neuropathic pain

Mandlem, V., Rivera, A., Khan, Z., Quazi, S. H., & Deba, F. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1472771 · Cited by 11

Plant-derived compounds and neurodegenerative diseases: Different mechanisms of action with therapeutic potential

Echeverry, C., Pazos, M., Torres‐Pérez, M., & Prunell, G. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.12.039 · Cited by 12

Propofol and α2-Agonists Attenuate Microglia Activation and Restore Mitochondrial Function in an In Vitro Model of Microglia Hypoxia/Reoxygenation

Longhitano, L., Distefano, A., Murabito, P., Astuto, M., Nicolosi, A., Buscema, G., Sanfilippo, F., Lazzarino, G., Amorini, A. M., Bruni, A., et al. (2022) · Antioxidants · doi:10.3390/antiox11091682 · Cited by 12

Microglia-Induced Maladaptive Plasticity Can Be Modulated by NeuropeptidesIn Vivo

Morara, S., Colangelo, A. M., & Provini, L. (2015) · Neural Plasticity · doi:10.1155/2015/135342 · Cited by 12

Role of SARS-CoV-2 in Modifying Neurodegenerative Processes in Parkinson’s Disease: A Narrative Review

Morowitz, J. M., Pogson, K., Roque, D., & Church, F. (2022) · Brain Sciences · doi:10.3390/brainsci12050536 · Cited by 11

Cannabinoid Receptor-2 Alleviates Sepsis-Induced Neuroinflammation by Modulating Microglia M1/M2 Subset Polarization Through Inhibiting Nogo-B Expression

Chen, S., Li, Z., Liu, Y., Xu, Z., Liu, A., He, Q., Xiao, F., & Zhan, J. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04836-2 · Cited by 11

Investigations into the Role of Metabolism in the Inflammatory Response of BV2 Microglial Cells

Maher, P. A. (2021) · Antioxidants · doi:10.3390/antiox10010109 · Cited by 10

Galectin-3 Plays a Role in Neuroinflammation in the Visual Pathway in Experimental Optic Neuritis

Funaki, M., Nio‐Kobayashi, J., Suzuki, R., & Bandô, Y. (2024) · Cells · doi:10.3390/cells13070612 · Cited by 11

Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells

Phan, C., Sabaratnam, V., Bovicelli, P., Righi, G., & Saso, L. (2016) · BioFactors · doi:10.1002/biof.1296 · Cited by 10

Mitochondrial Autophagy and NLRP3 Inflammasome in Pulmonary Tissues from Severe Combined Immunodeficient Mice after Cardiac Arrest and Cardiopulmonary Resuscitation

Lyu, J., Mehta, J. L., Li, Y., Ye, L., Sun, S., Sun, H.-S., Li, J.-C., Zhang, D., & Wei, J. (2018) · Chinese Medical Journal · doi:10.4103/0366-6999.231519 · Cited by 10

Short-Term Effects of Microglia-Specific Mitochondrial Dysfunction on Amyloidosis in Transgenic Models of Alzheimer’s Disease

Steffen, J., Stenzel, J., Ibrahim, S. M., & Pahnke, J. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180395 · Cited by 11

Blueberries and insulin protect microglial cells against high glucose-induced inflammation and restore GLUT-1

Hininger‐Favier, I., Thangthaeng, N., Bielinski, D. F., Fisher, D. R., Poulose, S. M., & Shukitt‐Hale, B. (2021) · Journal of Berry Research · doi:10.3233/jbr-200628 · Cited by 9

Specific signaling by nicotinamide adenine dinucleotide oxidases – Role of their site of action

Schröder, K. (2024) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2024.102461 · Cited by 9

Potential role of mitochondrial damage and S9 mixture including metabolic enzymes in ZnO nanoparticles-induced oxidative stress and genotoxicity in Chinese hamster lung (CHL/IU) cells

Yanagisawa, H., Seki, Y., Yogosawa, S., Takumi, S., Shimizu, H., & Suka, M. (2018) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2018.07.003 · Cited by 9

Comparison of Candesartan and Angiotensin-(1-7) Combination to Mito-TEMPO Treatment for Normalizing Blood Pressure and Sympathovagal Balance in (mREN2)27 Rats

Nautiyal, M., Shaltout, H. A., Chappell, M. C., & Diz, D. I. (2018) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000645 · Cited by 9

Oxysterols in the development of diabetes and cardiovascular diseases

Poli, G., Biasi, F., & Leoni, V. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.06.001 · Cited by 8

Chronic Oxaliplatin Treatment Induces CIPN in Mice via Activation of the TXNIP Pathway

Du, J., Sudlow, L. C., Shahverdi, K., Zhou, H., Yuede, C. M., Crock, L. W., Hunter, D. A., Golden, J. P., Mollah, S. A., Wood, M. D., et al. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05463-7 · Cited by 8

The main signaling pathways determining the microglia responses in spinal cord injury: Potential effectors among known pharmaceuticals

Akhmetzyanova, E. R., Rizvanov, A. A., & Mukhamedshina, Y. O. (2025) · Experimental Neurology · doi:10.1016/j.expneurol.2025.115523 · Cited by 8

The NADPH Oxidase Inhibitor, Mitoapocynin, Mitigates DFP-Induced Reactive Astrogliosis in a Rat Model of Organophosphate Neurotoxicity

Meyer, C., Grego, E., Vasanthi, S. S., Rao, N. S., Massey, N., Holtkamp, C., Huss, J., Showman, L. J., Narasimhan, B., & Thippeswamy, T. (2023) · Antioxidants · doi:10.3390/antiox12122061 · Cited by 7

Elucidating the Neuroprotective Effect of Tecoma stans Leaf Extract in STZ-Induced Diabetic Neuropathy

Gupta, A. K., Behl, T., Sehgal, A., Singh, S., Sharma, N., Yadav, S., Anwer, K., Vargas-De-La-Cruz, C. B., Chigurupati, S., Farasani, A. M., et al. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/3833392 · Cited by 9

Mitochondria-Targeted Human Catalase in the Mouse Longevity MCAT Model Mitigates Head-Tilt Bedrest-Induced Neuro-Inflammation in the Hippocampus

Rubinstein, L., Kiffer, F. C., Puukila, S., Lowe, M. G., Goo, B., Luthens, A., Schreurs, A., Torres, S. M., Steczina, S., Tahimic, C. G. T., et al. (2022) · Life · doi:10.3390/life12111838 · Cited by 7

Oxytocin and Neuroprotective Effects

Erbaş, O., & Altuntaş, İ. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.96527 · Cited by 6

Breaking Barriers in Alzheimer’s Disease: the Role of Advanced Drug Delivery Systems

Shekho, D., Mishra, R., Kamal, R., Bhatia, R., & Awasthi, A. (2024) · AAPS PharmSciTech · doi:10.1208/s12249-024-02923-6 · Cited by 6

Looking for CO 2 : Exploring the Novel Finding of Low Respiratory Quotient After Cardiac Arrest

Berg, K. M., Donnino, M. W., & Callaway, C. W. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.009500 · Cited by 6

The effect of intranasally administered TLR3 agonist larifan on metabolic profile of microglial cells in rat with C6 glioma

Hurmach, Y., Rudyk, M. P., Svyatetska, V., Senchylo, N., Skachkova, O., Pjanova, D., Vaivode, K., & Skivka, L. M. (2018) · The Ukrainian Biochemical Journal · doi:10.15407/ubj90.06.110 · Cited by 5

Estrogen-related receptor α (ERRα) functions in the hypoxic injury of microglial cells

Deng, C.-Y., Zhu, T., Lian, S., Wang, J., Wu, R., & Zheng, J. (2022) · Journal of Veterinary Research · doi:10.2478/jvetres-2022-0009 · Cited by 5

Deletion of NADH oxidase in Listeria monocytogenes promotes the bacterial infection of brain

Li, S., Yu, W., Guan, X., Luo, Z., Chen, G., Liu, W., & Zhang, J. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.09.003 · Cited by 5

Emerging Role of Calycosin in Inflammatory Diseases: Molecular Mechanisms and Potential Therapeutic Applications

Liu, T., Ye, Y., Hu, Y., & Jiang, M. (2025) · Biomolecules · doi:10.3390/biom15121643 · Cited by 4

Pathological Sequelae of SARS-CoV-2: A Review for Clinicians

Nyarko, J. A., Dogbe, P. M., Ativi, L. A. E., Wutsika, J., Agyenim, E. B., Awere‐Duodu, A., Botaeng, A. T., & Ntim, N. A. A. (2024) · The Yale Journal of Biology and Medicine · doi:10.59249/dqjh2274 · Cited by 4

Deacceleration of Brain Aging by Melatonin

Hardeland, R. (2016) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-319-33486-8_18 · Cited by 4

Brief pup separation during lactation confers resilience in behavioural deficits induced by chronic restraint stress in postpartum C57BL/6J dams

Zhou, L., Wu, Z., Zhao, D., Wang, G., Xiao, L., Wang, H., Xie, Y., & Sun, L. (2023) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.220079 · Cited by 3

Aruncus dioicus var. kamtschaticus extract suppresses mitochondrial apoptosis induced‐neurodegeneration in trimethyltin‐injected ICR mice

Park, S. B., Kang, J. Y., Kim, J. M., Park, S. K., Park, S. H., Kang, J. E., Lee, C. J., Kwon, B. S., Yoo, S. K., Lee, U., et al. (2018) · Journal of Food Biochemistry · doi:10.1111/jfbc.12667 · Cited by 4

Lactobacillus rhamnosus RL-H3-005 ameliorates Enterococcus faecium-induced pulmonary inflammation via gut microbiota remodeling and macrophage polarization regulation

Li, S., Tong, Y., Li, Y., Sui, D., Li, H., Zhao, S., & Ren, X. (2025) · Food Research International · doi:10.1016/j.foodres.2025.118239 · Cited by 3

Glial lactate metabolism and transport in Alzheimer’s disease

Wang, Y., Feng, B., Hong, R., Qiu, D., Zhao, J., & Zhao, L. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1731089 · Cited by 3

An introduction to innate immunity in the central nervous system

Harry, G. J., Childers, G. M., & McPherson, C. A. (2018) · Advances in neurotoxicology · doi:10.1016/bs.ant.2018.10.002 · Cited by 3

The Emerging Role of Phosphodiesterase Inhibitors in Fragile X Syndrome and Autism Spectrum Disorder

Thomas, S. D., Mohammed, H. A., Hamad, M. I. K., Öz, M., Statsenko, Y. A., & Sadek, B. S. (2025) · Pharmaceuticals · doi:10.3390/ph18101507 · Cited by 2

Molecular Networks of Redox Dysregulation in Fetal Alcohol Spectrum Disorders: Mechanisms and Therapeutic Prospects

Wang, X., & Chen, S.-Y. (2026) · Antioxidants · doi:10.3390/antiox15040470 · Cited by 2

The A53T mutation in α-synuclein enhances pro-inflammatory activation in human microgliaPreprint

Krzisch, M., Yuan, B., Chen, W., Osaki, T., Fu, D., Garrett-Engele, C. M., Svoboda, D. S., Andrykovich, K. R., Sur, M., & Jaenisch, R. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.29.555300 · Cited by 2

Fabrication and optimization of verapamil-loaded PEGylated nanoparticles for management of traumatic brain injury: a comparative evaluation

Amin, O. M., Khalifa, M. K. A., El-Fattah, M. A. A., Allam, A., Aboutaleb, A. S., & Al‐Najjar, A. H. (2025) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2025.2592102 · Cited by 1

Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration

Araújo-Rodrigues, H., Garzón‐García, L., Salsinha, A. S., Relvas, J. B., Tavaria, F. K., Santos‐Buelga, C., Gonzaléz‐Paramás, A. M., & Pintado, M. (2025) · Nutrients · doi:10.3390/nu17243867 · Cited by 2

Bifidobacterium pseudocatenulatum AL44 ameliorates Enterococcus faecium-induced lung inflammation through NLRP3 suppression along the gut-lung axis

Li, S., Zheng, W., Wang, W., Ren, X., Song, S., & Ai, C. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108395 · Cited by 1

TREM1 inhibition via LP17 alleviates secondary spinal cord injury by activating AMPKα-PINK1-parkin-dependent microglial mitophagy

Zia, B., Sun, Y., Liu, J., & Lin, J. (2026) · Neuropeptides · doi:10.1016/j.npep.2026.102619 · Cited by 1

Methylene Blue for Prevention of Perioperative Neurocognitive Disorders: Mechanisms and Recent Clinical Evidence

Wu, Y., Wang, J., & Wan, X. (2026) · Drug Design Development and Therapy · doi:10.2147/dddt.s602971 · Cited by 1

Oxidative Stress in Schizophrenia: Relation to Neurochemical Pathogenetic Hypotheses

Burbaeva, G. S., Prokhorova, T. A., Savushkina, O. K., Терешкина, Е. Б., Vorobyeva, E. A., & Бокша, И. С. (2024) · Psikhiatriya · doi:10.30629/2618-6667-2023-21-6-85-99 · Cited by 1

Implication of Galectin-3 for Neuroinflammation in the Visual Pathway of the Experimental Optic NeuritisPreprint

Funaki, M., Nio‐Kobayashi, J., Suzuki, R., & Bandô, Y. (2023) · Preprints.org · doi:10.20944/preprints202311.0095.v1 · Cited by 1

Commentary: What do comparative studies on oxidative stress biomarkers actually tell us?

Amin, A., & Zaman, W. (2026) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2026.111219 · Cited by 1

Microglia: Features of Polarization and Aging

Harry, G. J., & McPherson, C. A. (2016) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-319-33486-8_3

Immunopathology of the Nervous System

Remick, A. K., Pershing, M. L., Papenfuss, T. L., Lanigan, L. G., Beck, M. J., & Toot, J. (2017) · Molecular and integrative toxicology · doi:10.1007/978-3-319-47385-7_5 · Cited by 1

Insulin signaling and microglia in the young and aged brain

Haas, C. B. (2021) · doi:10.33612/diss.183132348

Microglia Aging

Patro, N., Kushwaha, S. S., & Patro, I. K. (2022) · Springer eBooks · doi:10.1007/978-981-16-8313-8_20

Bioresponsive Nanomaterials for CNS Disease

Kudryashev, J. A., Madias, M. I., & Kwon, E. J. (2022) · Springer eBooks · doi:10.1007/978-3-031-11409-0_5

Malonyl-CoA Decarboxylase: A Spotlight on Brain Aspects

Fonseca-Teixeira, M., Brito, E. S., Beltrao-Valente, C., Ferreira, B. K., Schuck, P. F., & Ferreira, G. C. (2026) · Brain Sciences · doi:10.3390/brainsci16020220 · Cited by 1

Biological Applications of Nanozymes in Stroke: Current Progress and Future Directions

Liu, J., Qi, J., Lin, Y., Ding, C., & Zhu, Y. (2026) · ACS Nano Medicine · doi:10.1021/acsnanomed.5c00169

Genetics, Microbial Dysbiosis, and Neurodevelopmental Syndromes

Indhu, S., Vilmasen, P., Saranraj, P., Lokeshwari, B., & Phiri, S. (2026) · IGI Global eBooks · doi:10.4018/979-8-3373-8485-6.ch010

Microglia extracellular traps (MiETs) in Neurodegeneration: Mechanisms, Evidence Gaps, and Untapped Therapeutic Promise

Sha, L., & Jha, S. (2026) · Advances in immunology · doi:10.1016/bs.ai.2026.04.008

Loss of microglial ATM drives synaptic pruning and cognitive impairment in epilepsy

Hu, Y., Zhao, J. J., Wang, Y., Tan, M., Wang, L., Qi, H., Yang, J., & Zhu, X. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.07.021

Molecular toxicology of metal exposure: Oxidative stress induction and cytotoxic mechanistic pathways

Kumar, M., Bhoi, B., & Kumar, S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44299-5.00019-5

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

Chéret, C., Gervais, A., Lelli, A., Colin, C., Amar, L., Ravassard, P., Mallet, J., Cumano, A., Krause, K.-H., & Mallat, M. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.3568-08.2008 · Cited by 225

NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease

Haslund‐Vinding, J., McBean, G., Jaquet, V, & Vilhardt, F. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13425 · Cited by 169

SOD1 overexpression alters ROS production and reduces neurotoxic inflammatory signaling in microglial cells

Dimayuga, F. O., Wang, C., Clark, J. M., Dimayuga, E. R., Smith, V. D., & Bruce‐Keller, A. J. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.10.003 · Cited by 87

Analysis of Microglial Production of Reactive Oxygen and Nitrogen Species

Neniškytė, U., & Brown, G. C. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-520-0_12 · Cited by 9

Neurobiology of Disease Neurotoxic Activation of Microglia Is Promoted by a Nox1- Dependent NADPH Oxidase

Chéret, C., Gervais, A., Lelli, A., Colin, C., Amar, L., Mallet, J. J., Cumano, A., Krause, K.-H., & Mallat, M. (2013)