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Cited by 1,069

The DOI matches its Crossref record; 152 of the 152 references it cites were found in a registry or an index.

Roles, Functions, and Mechanisms of Long Non-Coding RNAs in Cancer

Open access
Fang, Yiwen, Fullwood, Melissa J.·2016·Genomics, Proteomics & Bioinformatics

Abstract

Long non-coding RNAs (lncRNAs) play important roles in cancer. They are involved in chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through a variety of chromatin-based mechanisms and via cross-talk with other RNA species. lncRNAs can function as decoys, scaffolds, and enhancer RNAs. This review summarizes the characteristics of lncRNAs, including their roles, functions, and working mechanisms, describes methods for identifying and annotating lncRNAs, and discusses future opportunities for lncRNA-based therapies using antisense oligonucleotides.

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Crossref · 10.1016/j.gpb.2015.09.006

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Metadata

Authors
Fang, Y., & Fullwood, M. J.
Venue
Genomics, Proteomics & Bioinformatics
Published
2016-02-01
Volume
14
Issue
1
Pages
42-54
ISSN
  • 1672-0229 (ISSN-L)
  • 2210-3244
OpenAlex
W2259090596
Cited by
1,069
References
152
FWCI
22.68
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Roles, Functions, and Mechanisms of Long Non-Coding RNAs in Cancer. https://app.cochat.ai/papers/10.1016/j.gpb.2015.09.006
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Fang, Y., & Fullwood, M. J. (2016). Roles, Functions, and Mechanisms of Long Non-Coding RNAs in Cancer. Genomics, Proteomics & Bioinformatics. https://doi.org/10.1016/j.gpb.2015.09.006

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.