Automated analysis of images for molecular quantification in immunohistochemistry

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Image segmentation techniques

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Prognostic and predictive factors in breast cancer by immunohistochemical analysis.

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Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling

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Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican

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The necessity of and strategies for improving confidence in the accuracy of western blots

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Automated Quantitative Analysis (AQUA) of In Situ Protein Expression, Antibody Concentration, and Prognosis

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Progression in Cutaneous Malignant Melanoma Is Associated with Distinct Expression Profiles

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Reversal of hippocampal neuronal maturation by serotonergic antidepressants

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Image Segmentation Techniques

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Interpretation and Quantification of Immunostains

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Hierarchical Clustering Analysis of Tissue Microarray Immunostaining Data Identifies Prognostically Significant Groups of Breast Carcinoma

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Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity

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Strong Immunostaining for Myogenin in Rhabdomyosarcoma Is Significantly Associated with Tumors of the Alveolar Subclass

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A Robust Automated Measure of Average Antibody Staining in Immunohistochemistry Images

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Quantitative Immunohistochemistry by Measuring Cumulative Signal Strength Using Commercially Available Software Photoshop and Matlab

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The relevance of antibody concentration to the immunohistological quantification of cell proliferation‐associated antigens

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Sensitive Immunoassay of Tissue Cell Proteins Procured by Laser Capture Microdissection

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Structural and Functional Evidence for Discrete Exit Pathways That Connect the Canine Sinoatrial Node and Atria

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Chronic fluoxetine treatment alters the structure, connectivity and plasticity of cortical interneurons

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CREB-Dependent Regulation of GAD65 Transcription by BDNF/TrkB in Cortical Interneurons

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Chronic fluoxetine treatment increases the expression of PSA-NCAM in the medial prefrontal cortex

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Isoflurane produces antidepressant effects and induces TrkB signaling in rodents

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Quantitative neurite outgrowth measurement based on image segmentation with topological dependence

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Chronic restraint stress down-regulates amygdaloid expression of polysialylated neural cell adhesion molecule

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Chronic fluoxetine treatment in middle-aged rats induces changes in the expression of plasticity-related molecules and in neurogenesis

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Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment Induce Changes in the Structure and Neurochemistry of Inhibitory Neurons of the Adult Amygdala and Prefrontal Cortex

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Color Subtractive–Computer-assisted Image Analysis for Quantification of Cutaneous Nerves in a Diabetic Mouse Model

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Immunocytochemical detection of regional protein changes in rat brain sections using computer-assisted image analysis.

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Crowdsourcing scoring of immunohistochemistry images: Evaluating Performance of the Crowd and an Automated Computational Method

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A Quantitative Immunohistochemical Study of the Cellular Response to Crush Injury in Optic Nerve

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Semi-quantitative Determination of Protein Expression Using Immunohistochemistry Staining and Analysis: An Integrated Protocol

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Perineuronal Nets Regulate the Inhibitory Perisomatic Input onto Parvalbumin Interneurons and γ Activity in the Prefrontal Cortex

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Imaging Synaptic Density: The Next Holy Grail of Neuroscience?

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Detecting Early Cognitive Decline in Alzheimer’s Disease with Brain Synaptic Structural and Functional Evaluation

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Glioprotective Effect of Chitosan-Coated Rosmarinic Acid Nanoemulsions Against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Rat Astrocyte Primary Cultures

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QuantiMus: A Machine Learning-Based Approach for High Precision Analysis of Skeletal Muscle Morphology

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Δ-9-Tetrahydrocannabinol treatment during adolescence and alterations in the inhibitory networks of the adult prefrontal cortex in mice subjected to perinatal NMDA receptor antagonist injection and to postweaning social isolation

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The tracts, cytoarchitecture, and neurochemistry of the spinal cord

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Post-weaning social isolation in male mice leads to abnormal aggression and disrupted network organization in the prefrontal cortex: Contribution of parvalbumin interneurons with or without perineuronal nets

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Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice

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Effects of Aging on the Structure and Expression of NMDA Receptors of Somatostatin Expressing Neurons in the Mouse Hippocampus

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TAF1-gene editing alters the morphology and function of the cerebellum and cerebral cortex

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Analysis of Differential Expression of Synaptic Vesicle Protein 2A in the Adult Rat Brain

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PSA Depletion Induces the Differentiation of Immature Neurons in the Piriform Cortex of Adult Mice

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Nrg1 haploinsufficiency alters inhibitory cortical circuits

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Identification of a Suitable Untargeted Agent for the Clinical Translation of ABY-029 Paired-Agent Imaging in Fluorescence-Guided Surgery

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Long term effects of 24-h-restraint stress on the connectivity and structure of interneurons in the basolateral amygdala

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Astrocytes contribute to the neuronal recovery promoted by high‐frequency repetitive magnetic stimulation in in vitro models of ischemia

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Gene Editing to Generate Versatile Human Pluripotent Stem Cell Reporter Lines for Analysis of Differentiation and Lineage Tracing

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Adenosine mediates the amelioration of social novelty deficits during rhythmic light treatment of 16p11.2 deletion female mice

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Automatic Quantification of Cardiomyocyte Dimensions and Connexin 43 Lateralization in Fluorescence Images

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CCL2 signaling promotes skeletal muscle wasting in non-tumor and breast tumor models

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Adenosine A2A and A3 Receptors as Targets for the Treatment of Hypertensive-Diabetic Nephropathy

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Effects of the Genetic Depletion of Polysialyltransferases on the Structure and Connectivity of Interneurons in the Adult Prefrontal Cortex

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Role of C5aR1 and C5L2 Receptors in Ischemia-Reperfusion Injury

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Diabetes downregulates renal adenosine A2A receptors in an experimental model of hypertension

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Erythropoietin restrains the inhibitory potential of interneurons in the mouse hippocampus

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Impact of automated methods for quantitative evaluation of immunostaining: Towards digital pathology

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Long term effects of peripubertal stress on the thalamic reticular nucleus of female and male mice

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Implication of RAS in Postnatal Cardiac Remodeling, Fibrosis and Dysfunction Induced by Fetal Undernutrition

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Role of the CXCR4/ALK5/Smad3 Signaling Pathway in Cancer-Induced Bone Pain

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Vascular impairment of adenosinergic system in hypertension: increased adenosine bioavailability and differential distribution of adenosine receptors and nucleoside transporters

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Early chronic fasudil treatment rescues hippocampal alterations in the Ts65Dn model for down syndrome

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SPECHT: Self-tuning Plausibility based object detection Enables quantification of Conflict in Heterogeneous multi-scale microscopy

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Deafening noise down-regulates dopamine transmission in the hub of the central auditory system

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Altered expression of vesicular glutamate transporter-2 and cleaved caspase-3 in the locus coeruleus of nerve-injured rats

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Dark exposure affects plasticity‐related molecules and interneurons throughout the visual system during adulthood

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Enhancement of spatial learning by 40 Hz visual stimulation requires parvalbumin interneuron-dependent hippocampal neurogenesisPreprint

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The role of artificial intelligence and the internet of things in chitosan synthesis and electrochemical sensors applications: A brief overview

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How the variability between computer-assisted analysis procedures evaluating immune markers can influence patients’ outcome prediction

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Advancing Biological Research: New Automated Analysis of Immunofluorescence Signals

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Fabrication of microfluidic paper-based channels by inkjet printing process for analytical applications

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Cancer neuroscience: Dissecting autonomic and sensory neural regulation of tumor progression and therapeutic resistance

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Depletion of Neurocan in the Prefrontal Cortex Impairs Temporal Order Recognition, Cognitive Flexibility and Perisomatic GABAergic Innervation

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In utero exposure to anti-Caspr2 antibody disrupts parvalbumin interneuron function in the hippocampus

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Combined BRCA2 and MAGEC3 Expression Predict Outcome in Advanced Ovarian Cancers

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Development of an Automated Image Analyzer for Microvessel Density Measurement in Bone Marrow Biopsies

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Immunohistochemistry as a detection tool for ion channels involved in dental pain signaling

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Validation of a semi-quantitative scoring system and workflow for analysis of fluorescence quantification in companion animals

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Losartan alleviated synovitis in patients with metabolic osteoarthritis by down-regulating AT1R to inhibit TGF-β signaling

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Dissection and Immunohistochemistry of the Drosophila Adult Leg to Detect Changes at the Neuromuscular Junction for an Identified Motor Neuron

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A Clonogenic Assay to Quantify Melanoma Micrometastases in Pulmonary Tissue

Mattei, F., Andreone, S., & Schiavoni, G. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1205-7_28 · Cited by 2 · see citing works

Automated Quantification of CD44, c-MET, EGFR, MTOR, and GLUT1 Expression in Head and Neck Squamous Cell Carcinoma: The Impact of p16 Status and Response to Chemoradiation

Wilson, G. D., Arden, J. D., Quinn, T. J., Wilson, T. G., Hanna, A., Barker, K., Deraniyagala, R. L., Baschnagel, A. M., & Wilson, G. D. (2020) · Clinical Oncology and Research · doi:10.31487/j.cor.2020.06.03 · Cited by 1 · see citing works

Strain- and age-dependent features of the nigro-striatal circuit in three common laboratory mouse strains, C57BL/6J, A/J, and DBA/2J - Implications for Parkinson’s disease modelingPreprint

Thomas, M. H., Karout, M., Rodriguez, B. P., Gui, Y., Jaeger, C., Michelucci, A., Kollmus, H., Schughart, K., Coowar, D., Balling, R., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.30.404293 · Cited by 1 · see citing works

Dissection and Immunohistochemistry of the Drosophila Adult Leg to Detect Changes at the Neuromuscular Junction for an Identified Motor Neuron

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Neutrophil Extracellular Traps Drive a skin–kidney inflammatory axis in UVB-Irradiated Lupus-Prone MicePreprint

Lyu, X., Li, M., Li, M., Zhang, P. L., Wei, W., Werth, V. P., & Liu, M. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.12.23.572573

Regulatory T cell infiltration precedes early events associated with persistent infectious bronchitis virus (IBV) infection in the cecal tonsils of chickens

Suhail, S. M., Isham, I. M., Farooq, M., Azhar, M., Ali, A., Mahmoud, M. E., Ghaffar, A., Herath-Mudiyanselage, H., Cork, S. C., Gupta, A. V., et al. (2025) · Virology · doi:10.1016/j.virol.2025.110691

Age-Related Changes in Density, Arborization and Expression of NMDA Receptors of Somatostatin Martinotti Neurons in the Mouse mPFCPreprint

Sánchez-Moreno, B., Gramuntell, Y., Klimczak, P., Backer, E. D., Nácher, J., & Gilabert‐Juan, J. (2025) · Research Square · doi:10.21203/rs.3.rs-7657662/v1

Erythropoietin targets parvalbumin-positive inhibitory neurons and microglia to promote plasticity in the thalamic reticular nucleus

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Early-life medial pulvinar disruption drives schizophrenia-relevant prefrontal inhibitory and cognitive deficits in primatesPreprint

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DGIST: A standardized image-based spatial quantification workflow for neurogenesis in the dentate gyrus

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Age‐Related Changes in Density, Arborization, and NMDA Receptor Expression in Somatostatin Interneurons of the Mouse mPFC

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A semi-automated pipeline integrating ImageJ/Fiji and StarDist for the reproducible quantification of cellular and optical density metrics in immunofluorescence images of brain tissue

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Quantitative Immunohistochemistry for the Investigation of Regulatory Peptides in Health and Disease

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Automated Macro Approach to Quantify Synapse Density in 2D Confocal Images from Fixed Immunolabeled Neural Tissue Sections

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New automatic quantification method of immunofluorescence and histochemistry in whole histological sections

Kessel, F., Steglich, A., Tschongov, T., Gembardt, F., Ruhnke, L., Stumpf, J., Behrendt, R., Cohrs, C. M., Kopaliani, I., Todorov, V., et al. (2019) · Cellular Signalling · doi:10.1016/j.cellsig.2019.05.020 · Cited by 10 · see citing works

TissueProf: An ImageJ/Fiji Plugin for Tissue Profiling Based on Fluorescent Signals

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