The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure
Open accessAbstract
Synopsis Aging represents a convergence of declining cardioprotective systems and increasing disease processes that is fertile ground for the development of heart failure. With 50% of all heart failure diagnoses and 90% of all heart failure deaths occurring in the segment of the population over age 70, heart failure is largely a disease of the elderly. This review discusses the microscopic and macroscopic changes in cardiovascular structure, function, protective systems, and disease associated with aging. In addition to outlining important clinical considerations and conditions in older persons, the link between normal aging and the elevated risk for development of stage B heart failure is explained and potential therapeutic pathways highlighted.
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Cites
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Self-citationIrbesartan in patients with heart failure and preserved ejection fraction
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Self-citationNADPH Oxidases in Cardiovascular Health and Disease
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Self-citationAge-associated Cardiovascular Changes in Health: Impact on Cardiovascular Disease in Older Persons
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Self-citationCOL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan
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2013 ETA Guideline: Management of Subclinical Hypothyroidism
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Length-independent telomere damage drives post-mitotic cardiomyocyte senescence
Anderson, R., Lagnado, A., Maggiorani, D., Walaszczyk, A., Dookun, E., Chapman, J., Birch, J., Salmonowicz, H., Ogrodnik, M., Jurk, D., et al. (2019) · The EMBO Journal · doi:10.15252/embj.2018100492 · Cited by 532
“During ageing, the heart undergoes distinct physiological and molecular changes, including cardiomyocyte (CM) hypertrophy and increased fibrosis, which contribute to increased ventricular stiffness causing a reduction in diastolic but not systolic cardiac function (Strait & Lakatta, 2012).”
Exercise Intolerance in Patients With Heart Failure
Del Buono, M. G., Arena, R., Borlaug, B. A., Carbone, S., Canada, J. M., Kirkman, D. L., Garten, R., Rodriguez-Miguelez, P., Guazzi, M., Lavie, C. J., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.01.072 · Cited by 477
Aging human body: changes in bone, muscle and body fat with consequent changes in nutrient intake
JafariNasabian, P., Inglis, J. E., Reilly, W., Kelly, O. J., & Ilich, J. Z. (2017) · Journal of Endocrinology · doi:10.1530/joe-16-0603 · Cited by 310
Autophagy in Cardiovascular Aging
Abdellatif, M., Sedej, S., Carmona-Gutierrez, D., Madeo, F., & Kroemer, G. (2018) · Circulation Research · doi:10.1161/circresaha.118.312208 · Cited by 239
Metadata
- Authors
- Strait, J. B., & Lakatta, E. G.
- Venue
- Heart Failure Clinics
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 8
- Issue
- 1
- Pages
- 143-164
- ISSN
- 1551-7136 (ISSN-L)
- OpenAlex
- W2077686023
- Cited by
- 739
- References
- 11
- FWCI
- 7.59
- Type
- journal article
- Language
- en
- Open access
- green
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