Acidified nitrite as a potential antifungal agent
Abstract
The use of acidified nitrite as a potential antifungal agent was investigated by exposing clinical isolates of Candida albicans, Candida glabrata, Candida tropicalis, Cryptococcus neoformans, Aspergillus fumigatus and Rhodotorula to varying concentrations of acidified nitrite at different pH levels to determine the minimal fungicidal concentration after 10 min exposure.
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Acidified nitrite exhibits bactericidal action against several pathogens in other tissue compartments including the skin, dental caries, and gastric mucosa.
“Acidified nitrite also exhibits bactericidal action against several pathogens in other tissue compartments including the skin, dental caries, and gastric mucosa [201–206].”
From Inorganic nitrite therapy: historical perspective and future directions (2011) · cites this paper as [201]
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- Authors
- Anyim, M., Benjamin, N., & Wilks, M.
- Affiliations
- Queen Mary University of London (GB)
- Derriford Hospital (GB)
- St Bartholomew's Hospital (GB)
- Corresponding author
- Wilks, M.
- ORCID
- Wilks, M.
- Venue
- International Journal of Antimicrobial Agents
- Publisher
- Elsevier BV
- Published
- 2005-07
- Volume
- 26
- Issue
- 1
- Pages
- 85-87
- ISSN
- 0924-8579 (ISSN-L)
- OpenAlex
- W1998028893
- Cited by
- 18
- References
- 19
- Citations by year
- 2026: 1 · 2025: 1 · 2022: 1 · 2021: 2 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 3
- FWCI
- 0.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Antimicrobial Agents (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Department for Environment, Food and Rural Affairs, UK Government
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Keywords
- antifungal agents, Candida albicans, Candida glabrata, Candida tropicalis, Cryptococcus neoformans, Aspergillus fumigatus, Rhodotorula, minimum fungicidal concentration, pH dependence, clinical fungal isolates
- MeSH terms
- Antifungal Agents, Aspergillus fumigatus, Candida, Cryptococcus neoformans, Hydrogen-Ion Concentration, Rhodotorula, Sodium Nitrite
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