Cited by 548Bone Tissue Engineering Materialsbiodegradable polymer synthesis and propertiesNanocomposite Films for Food Packaging

Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering

Swetha, Maddela, Sahithi, Kolli, Moorthi, Ambigapathi, Srinivasan, Narasimhan, Ramasamy, Kumarasamy, Selvamurugan, Nagarajan·2010·International Journal of Biological Macromolecules

Abstract

Bone tissue engineering is an alternative strategy to generate bone utilizing a combination of biomaterials and cells. Biomaterials that mimic the structure and composition of bone tissues at nanoscale are important for the development of bone tissue engineering applications. Natural or biopolymer-based composites containing chitin, chitosan, or collagen have advantages such as biocompatibility, biodegradability that are essential for bone tissue engineering. The inclusion of nanoparticles of hydroxyapatite (one of the most widely used bioceramic materials) into the biopolymer matrix improves the mechanical properties and incorporates the nanotopographic features that mimic the nanostructure of bone. This review summarizes the recent work on the development of biocomposites containing natural polymers with hydroxyapatite particles suitable for use in bone defects/bone regeneration.

Integrity signals

Registry

Crossref · 10.1016/j.ijbiomac.2010.03.015

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Bone regenerative capacity is limited in large bone defects, requiring surgical procedures to prevent further degeneration.

    “Even though the bone can regenerate itself, its regenerative capacity is limited in the case of large bone defects and hence, requires surgical procedures to prevent it from further degeneration [3].”

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Swetha, M., Sahithi, K., Moorthi, A., Srinivasan, N., Ramasamy, K., & Selvamurugan, N.
Affiliations
  • SRM Institute of Science and Technology (IN)
  • University of Madras (IN)
Corresponding author
Selvamurugan, Nagarajan
Venue
International Journal of Biological Macromolecules
Publisher
Elsevier BV
Published
2010-07
Volume
47
Issue
1
Pages
1-4
ISSN
0141-8130 (ISSN-L)
OpenAlex
W2066518402
Cited by
548
References
43
Citations by year
2026: 13 · 2025: 18 · 2024: 37 · 2023: 33 · 2022: 36 · 2021: 47 · 2020: 42 · 2019: 57 · 2018: 47 · 2017: 30 · 2016: 44 · 2015: 37 · 2014: 35 · 2013: 21 · 2012: 28
FWCI
1.89
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Biological Macromolecules (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Physical Sciences › Materials Science › Biomaterials › Nanocomposite Films for Food Packaging
Keywords
bone tissue engineering, biocomposites, hydroxyapatite nanoparticles, natural polymers, chitosan, chitin, collagen, biodegradable biomaterials, bone regeneration, bone defects, nanotopography, mechanical properties
MeSH terms
Animals, Bone Regeneration, Chitin, Collagen, Humans, Durapatite, Bone Substitutes, Tissue Engineering, Chitosan, Nanoparticles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review