Cited by 57Bone Tissue Engineering MaterialsCollagen: Extraction and CharacterizationHydrogels: synthesis, properties, applications

Preparation and characterization of composites based on the blends of collagen, chitosan and hyaluronic acid with nano-hydroxyapatite

Sionkowska, Alina, Kaczmarek, Beata·2017·International Journal of Biological Macromolecules

Abstract

3D porous composites based on the blend of chitosan, collagen and hyaluronic acid with the addition of nano-hydroxyapatite were prepared. SEM images for the composites were made and the structure was assessed. Mechanical properties were studied using a Zwick&Roell Testing Mashine. In addition, the porosity and density of composites were measured. The concentration of calcium ions released from the material was detected by the complexometric titration method. The results showed that in 3D porous sponge based on the blend of chitosan, collagen and hyaluronic acid, inorganic particles of nanohydroxyapatite can be incorporated, as well as that the properties of 3D composites depend on the material composition. Mechanical parameters and thermal stability of ternary biopolymeric blends were improved by the addition of hydroxyapatite. Moreover, the porosity of ternary materials was higher than in materials based on pure chitosan or collagen. All composites were characterized by a porous structure with interconnected pores. Calcium ions can be released from the composite during its degradation in water.

Integrity signals

Registry

Crossref · 10.1016/j.ijbiomac.2017.03.196

Cites

41 of 41 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • A scaffold with better mechanical and thermal properties that can effectively support bone regeneration was prepared.

    “Scaffold with better mechanical and [98] | thermal properties that can | effectively support bone | regeneration was prepared.”

Cites

Flagged first, then by citations

2 of the 43 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Sionkowska, A., & Kaczmarek, B.
Affiliations
Nicolaus Copernicus University (PL)
Corresponding author
Sionkowska, Alina
Venue
International Journal of Biological Macromolecules
Publisher
Elsevier BV
Published
2017-09
Volume
102
Pages
658-666
ISSN
0141-8130 (ISSN-L)
OpenAlex
W2605320162
Cited by
57
References
43
Citations by year
2026: 3 · 2025: 3 · 2024: 3 · 2023: 5 · 2022: 3 · 2021: 12 · 2020: 12 · 2019: 5 · 2018: 9 · 2017: 2
FWCI
3.44
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Biological Macromolecules (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Science Centre (UMO-2013/11/B/ST8/04444)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
  • Physical Sciences › Materials Science › Biomaterials › Collagen: Extraction and Characterization
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
Keywords
collagen, chitosan, hyaluronic acid, hydroxyapatite nanoparticles, biopolymer blends, calcium ion release, porosity, mechanical properties, thermal stability, biodegradation, tissue engineering scaffolds
MeSH terms
Collagen, Hyaluronic Acid, Durapatite, Chitosan, Nanocomposites, Mechanical Phenomena

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review