Physicochemical Properties, Structural Characterization and Biological Activities of Polysaccharides from Quinoa (Chenopodium quinoa Willd.) Seeds
Abstract
In this paper, membrane separation technology was employed to separate polysaccharide fractions from the water extract of quinoa seeds. The chemical composition, structure characteristic and morphology were analyzed by chemical methods and instrumental analysis including HPLC-DAD, UV, FT-IR, Congo red test, SEM, AFM, XRD, TGA and NMR. Results indicated that three polysaccharide fractions named as QPs-I, QPs-II and QPs-III were successfully separated using microfiltration and ultrafiltration membrane with MWCO of 300 and 10 kDa in sequence. The Mw and polysaccharide content of three fractions were QPs-I (4609 Da, 33.75%), QPs-II (15,932 Da, 45.31%) and QPs-III (960,895 Da, 34.65%), respectively. The polysaccharide in three fractions was heteropolysaccharide that mainly consisted of glucose, galactose and arabinose, with their combined monosaccharide percentage being 91.17% in QPs-I, 87.81% in QPs-II, and 91.72% in QPs-III, respectively. All three polysaccharide fractions contained triple-helix structure. Biological experiment showed that antioxidant and antidiabetic activities in dose-dependent manners and also revealed immunoregulatory activity on RAW264.7 cells. These results indicated that QPs has the potential to be used in a natural agent in antioxidant, antidiabetic and immunoregulation functional food.
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In vitro studies reported quinoa's effects on gut microbiota and cancer cells, antioxidant and antidiabetic properties, platelet activity, and modulating collagenase activity.
“The in vitro studies presented in Table 7 reported quinoa’s effects on gut microbiota and cancer cells, antioxidant and antidiabetic properties, platelet activity, and modulating collagenase activity [201,202,203,204,205,206,207].”
From Ecdysterone and Turkesterone—Compounds with Prominent Potential in Sport and Healthy Nutrition (2024) · cites this paper as [205]
Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works
Colorimetric Method for Determination of Sugars and Related Substances
DuBois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., & Smith, F. (1956) · Analytical Chemistry · doi:10.1021/ac60111a017 · Cited by 52,269 · see citing works
A modified uronic acid carbazole reaction
Bitter, T., & Muir, H. M. (1962) · Analytical Biochemistry · doi:10.1016/0003-2697(62)90095-7 · Cited by 6,239 · see citing works
Kohen, R., & Nyska, A. (2002) · Toxicologic Pathology · doi:10.1080/01926230290166724 · Cited by 2,178 · see citing works
Yu, Y., Shen, M., Song, Q., & Xie, J. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.12.009 · Cited by 1,425 · see citing works
Macrophages in Tumor Microenvironments and the Progression of Tumors
Hao, N.-B., Lü, M.-H., Fan, Y.-H., Cao, Y.-L., Zhang, Z.-R., & Yang, S.-M. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/948098 · Cited by 1,003 · see citing works
Vega‐Gálvez, A., Miranda, M., Vergara, J., Uribe, E., Puente, L., & Martínez, E. A. (2010) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.4158 · Cited by 985 · see citing works
Advances in lentinan: Isolation, structure, chain conformation and bioactivities
Zhang, Y., Li, S., Wang, X., Zhang, L., & Cheung, P. C. K. (2010) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2010.02.001 · Cited by 449 · see citing works
Dai, J., Wu, Y., Chen, S., Zhu, S., Yin, H., Wang, M., & Tang, J. (2010) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.05.029 · Cited by 378 · see citing works
Podsędek, A., Majewska, I., Redzynia, M., Sosnowska, D., & Koziołkiewicz, M. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf5008264 · Cited by 267 · see citing works
Kim, J., Hyun, T. K., & Kim, M. J. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.08.020 · Cited by 261 · see citing works
Gao, J., Zhang, T., Jin, Z., Xu, X., Wang, J., Zha, X., & Chen, H.-Q. (2014) · Food Chemistry · doi:10.1016/j.foodchem.2014.08.016 · Cited by 223 · see citing works
Li, Q., Wang, W., Zhu, Y. J., Chen, Y., Zhang, W., Yu, P., Mao, G., Zhao, T., Feng, W., Yang, L., et al. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.12.041 · Cited by 207 · see citing works
Qian, J.-Y., Chen, W., Zhang, W., & Zhang, H. (2009) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2009.05.025 · Cited by 189 · see citing works
Hu, Y., Zhang, J., Zou, L., Fu, C., Li, P., & Zhao, G. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.03.019 · Cited by 176 · see citing works
Chen, Z., Zhao, Y., Zhang, M., Yang, X., Yue, P., Tang, D., & Wei, X. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.115362 · Cited by 172 · see citing works
Wang, Y., Yang, Z., & Wei, X. (2010) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2010.07.007 · Cited by 170 · see citing works
Ren, C., Zhang, Y., Weizheng, C., Lu, G., Wang, Y., Gao, H., Huang, L., & Mu, Z. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2014.09.060 · Cited by 167 · see citing works
Wang, K., Wang, J., Li, Q., Zhang, Q., You, R.-X., Cheng, Y., Luo, L., & Zhang, Y. (2014) · Food Research International · doi:10.1016/j.foodres.2014.02.047 · Cited by 162 · see citing works
Physicochemical characterization of quinoa (Chenopodium quinoa) flour and isolated starch
Contreras‐Jiménez, B., Vargas, O. L. T., & Rodríguez-García, M. E. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2019.124982 · Cited by 161 · see citing works
Chi, Y., Li, Y., Zhang, G., Gao, Y., Ye, H., Gao, J. F., & Wang, P. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.11.104 · Cited by 158 · see citing works
Xiao, H., Fu, X., Cao, C., Li, C., Chen, C., & Huang, Q. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.09.197 · Cited by 156 · see citing works
Composition of Atriplex hortensis , Sweet and Bitter Chenopodium quinoa Seeds
Wright, K., Pike, O. A., Fairbanks, D. J., & Huber, C. S. (2002) · Journal of Food Science · doi:10.1111/j.1365-2621.2002.tb10294.x · Cited by 154 · see citing works
Shi, M.-J., Wei, X., Xu, J., Chen, B.-J., Zhao, D., Cui, S., & Zhou, T. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.07.151 · Cited by 138 · see citing works
Ballesteros, L. F., Teixeira, J. A., & Mussatto, S. I. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.09.054 · Cited by 131 · see citing works
Liu, W., Wang, H., Yu, J., Liu, Y., Lu, W., Chai, Y., Liu, C., Pan, C. S., Yao, W., & Gao, X. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.05.011 · Cited by 122 · see citing works
Wang, L., Liu, F., Wang, A., Yu, Z., Xu, Y., & Yang, Y. (2016) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2016.12.003 · Cited by 119 · see citing works
Liang, X., Gao, Y., Pan, Y., Zou, Y., He, M., He, C.-L., Li, L., Yin, Z., & Lv, C. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.09.046 · Cited by 117 · see citing works
Zhang, L., Zhao, S., Lai, S., Chen, F., & Yang, H. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.08.013 · Cited by 109 · see citing works
Sulfation of tea polysaccharides: Synthesis, characterization and hypoglycemic activity
Wang, Y., Peng, Y., Wei, X., Yang, Z., Xiao, J., & Jin, Z. (2009) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2009.12.007 · Cited by 107 · see citing works
Isolation, structures and biological activities of polysaccharides from Chlorella: a review
Yuan, Q., Li, H., Wei, Z., Lv, K., Gao, C., Liu, Y., & Zhao, L. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.09.080 · Cited by 104 · see citing works
Ecdysteroids from Chenopodium quinoa Willd., an Ancient Andean Crop of High Nutritional Value
Kumpun, S., Maria, A., Crouzet, S., Evrard-Todeschi, N., Girault, J.-P., & Lafont, R. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2010.10.039 · Cited by 99 · see citing works
Hu, X., Pang, X., Wang, P. G., & Chen, M. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.09.069 · Cited by 99 · see citing works
Extraction and purification of pumpkin polysaccharides and their hypoglycemic effect
Wang, S., Lu, A., Zhang, L., Shen, M., Xu, T., Zhan, W., Jin, H. Z., Zhang, Y., & Wang, W. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.01.114 · Cited by 93 · see citing works
Thambiraj, S. R., Phillips, M., Koyyalamudi, S. R., & Reddy, N. (2015) · Industrial Crops and Products · doi:10.1016/j.indcrop.2015.06.028 · Cited by 90 · see citing works
Biological potential of extracts of the wild edible Basidiomycete mushroom Grifola frondosa
Klaus, A. S., Kozarski, M., Vunduk, J., Todorović, N. M., Jakovljević, D. M., Žižak, Ž. S., Pavlović, V. B., Lević, S., Nikšić, M., & Griensven, L. J. L. D. V. (2014) · Food Research International · doi:10.1016/j.foodres.2014.11.035 · Cited by 88 · see citing works
Wang, X.-T., Zhu, Z., Zhao, L., Sun, H.-Q., Meng, M., Zhang, J., & Zhang, Y. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.08.024 · Cited by 84 · see citing works
Wang, Y., & Zhang, H. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.11.208 · Cited by 83 · see citing works
Hong, P. K., Gottardi, D., Ndagijimana, M., & Betti, M. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.07.045 · Cited by 80 · see citing works
Antioxidant and Immunoregulatory Activity of Polysaccharides from Quinoa (Chenopodium quinoa Willd.)
Yao, Y., Shi, Z., & Ren, G. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms151019307 · Cited by 78 · see citing works
Zhang, Y., Xu, X., Xu, J., & Zhang, L. (2007) · Polymer · doi:10.1016/j.polymer.2007.09.005 · Cited by 77 · see citing works
Wu, J., Li, P., Tao, D., Zhao, H., Sun, R., Ma, F., & Zhang, B. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.05.191 · Cited by 77 · see citing works
Tan, M., Chang, S., Liu, J., Li, H., Xu, P., Wang, P., Wang, X. A., Zhao, M., Zhao, B., Wang, L., et al. (2020) · Molecules · doi:10.3390/molecules25173840 · Cited by 77 · see citing works
Self-citationShen, C., Li, Y., Jiang, J., Zheng, C., & Zhu, W. (2017) · Food & Function · doi:10.1039/c6fo01545j · Cited by 72 · see citing works
Satitmanwiwat, S., Ratanakhanokchai, K., Laohakunjit, N., Chao, L. K., Chen, S., Pason, P., Tachaapaikoon, C., & Kyu, K. L. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf300354x · Cited by 71 · see citing works
Studies on water soluble polysaccharides from Pithecellobium dulce (Roxb.) Benth. seeds
Bagchi, S., & Kumar, K. J. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.11.018 · Cited by 69 · see citing works
Hsu, W.-H., Qiu, W.-L., Tsao, S.-M., Tseng, A.-J., Lu, M., Hua, W.-J., Cheng, H.-C., Hsu, H.-Y., & Lin, T. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.09.227 · Cited by 69 · see citing works
Xiao, Y., Liu, S., Shen, M., Jiang, L. Z., Ren, Y., Luo, Y. F., Wen, H., & Xie, J. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.12.211 · Cited by 67 · see citing works
Zhao, S., Han, Z., Yang, L., Hong, B., & Zhu, H. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.02.015 · Cited by 47 · see citing works
Lee, Y.-K., Jung, S. K., & Chang, Y. H. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.02.307 · Cited by 43 · see citing works
Fan, S., Li, J., & Bai, B. (2019) · Bioscience Biotechnology and Biochemistry · doi:10.1080/09168451.2019.1650635 · Cited by 42 · see citing works
STRUCTURAL CHARACTERIZATION OF HEMICELLULOSES FROM BAMBOO CULMS (NEOSINOCALAMUS AFFINIS)
Sun, S., Yuan, T., Li, M. F., Cao, X., Xu, F., & Liu, Q. Y. (2012) · Cited by 38 · see citing works
Cai, M., Chen, S., Ma, Q., Yang, K., & Sun, P. (2019) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2019.04.068 · Cited by 33 · see citing works
Lin, Y., Shih, C., Cheng, P., Chin, C., Liou, A.-T., Lee, P., & Chiang, B. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.561758 · Cited by 27 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Zhao, H., Ren, S., Yang, H., Tang, S., Guo, C., Liu, M., Tao, Q., Ming, T., & Xu, H. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113559 · Cited by 242 · see citing works
Kashtoh, H., & Baek, K.-H. (2023) · Plants · doi:10.3390/plants12162944 · Cited by 213 · see citing works
Liu, C.-Y., Hu, D., Zhu, H., Zhang, Y.-Y., Qin, J., Wang, F., Zhang, Z., & Lv, G. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.06.122 · Cited by 71 · see citing works
Hu, Y., Hu, J.-L., Li, J., Wang, J., Zhang, X.-Y., Wu, X., Li, X., Guo, Z.-B., Zou, L., & Wu, D. (2022) · Food Research International · doi:10.1016/j.foodres.2022.112166 · Cited by 69 · see citing works
Huan, X., Li, L., Liu, Y., Kong, Z., Liu, Y., Wang, Q., Liu, J., Zhang, P., Guo, Y., & Qin, P. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.988861 · Cited by 58 · see citing works
Xi, X., Fan, G., Xue, H., Peng, S., Huang, W., & Zhan, J. (2024) · Antioxidants · doi:10.3390/antiox13070829 · Cited by 53 · see citing works
Hou, S.-B., Tan, M., Chang, S., Zhu, Y., Rong, G., Wei, G., Zhang, J., Zhao, B., & Zhao, Q. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125507 · Cited by 51 · see citing works
Self-citationZhang, X.-X., Ni, Z., Zhang, F., Thakur, K., Zhang, J., Khan, M. R., Busquets, R., & Wei, Z. (2022) · Food Chemistry X · doi:10.1016/j.fochx.2022.100282 · Cited by 51 · see citing works
Gao, Y., Tan, J., Sang, Y., Tang, J., Cai, X. D., & Xue, H. (2023) · Food Bioscience · doi:10.1016/j.fbio.2023.102909 · Cited by 49 · see citing works
Wang, J., Li, J., Zeng, D., Zhou, Z., Zhang, Y., Ye, G., Hu, S., Xin, N., Li, R., Cifuentes, A., et al. (2025) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2025.107477 · Cited by 40 · see citing works
Antitumor activity of Polygonatum sibiricum polysaccharides
Lai, W., Ning, Q., Wang, G., Gao, Y., Liao, S., & Tang, S. (2024) · Archives of Pharmacal Research · doi:10.1007/s12272-024-01511-3 · Cited by 38 · see citing works
Wang, H., Cheng, N., Wu, Q., Fang, D., Rahman, F., Hao, H., & Zhang, Y. (2024) · Journal of Dermatologic Science and Cosmetic Technology · doi:10.1016/j.jdsct.2024.100023 · Cited by 33 · see citing works
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Tak, Y., Kaur, M., Jain, M. C., Samota, M. K., Meena, N. K., Kaur, G., Kumar, R., Sharma, D., Lorenzo, J. M., & Amarowicz, R. (2022) · Polish Journal of Food and Nutrition Sciences · doi:10.31883/pjfns/152568 · Cited by 33 · see citing works
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Ji, X., Wang, Z., Hao, X., Zhu, Y., Lin, Y., Li, G., & Guo, X. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1012348 · Cited by 32 · see citing works
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Todorova, V., Ivanova, S., Chakarov, D., Kraev, K., & Ivanov, K. (2024) · Nutrients · doi:10.3390/nu16091382 · Cited by 31 · see citing works
“[205] The inhibition of collagenase activity of quinoa extracted ecdysteroids.”
BackgroundLiu, Y., Kan, Y., Huang, Y., Jiang, C., Zhao, L., Hu, J., & Pang, W. (2022) · Molecules · doi:10.3390/molecules27123719 · Cited by 31 · see citing works
Yu, S., Ma, R., Dong, X., Ji, H., & Liu, A.-J. (2022) · Industrial Crops and Products · doi:10.1016/j.indcrop.2022.115206 · Cited by 31 · see citing works
Zhu, H. L., Yi, X., Jia, S.-S., Liu, C.-Y., Han, Z., Han, B., Jiang, G.-C., Ding, Z., Wang, R., & Lv, G. (2023) · Molecules · doi:10.3390/molecules28248019 · Cited by 30 · see citing works
Li, J., Feng, J., Luo, X., Mo, M.-M. Q., Li, W.-B., Huang, J.-W., Wang, S., Hu, Y., Zou, L., & Wu, D. (2024) · Food Research International · doi:10.1016/j.foodres.2024.114395 · Cited by 30 · see citing works
Yang, X., Cao, D., Ji, H., Xu, H., Feng, Y., & Liu, A.-J. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124838 · Cited by 28 · see citing works
Wang, N., Chen, Z., Lv, J., Li, T., Wu, H., Wu, J., Wu, H., & Xiang, W. (2022) · Industrial Crops and Products · doi:10.1016/j.indcrop.2022.115936 · Cited by 27 · see citing works
Zhou, L., Jiao, Y., Tang, J., Zhao, Z., Zhu, H., Lu, Y., & Chen, D. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.10.027 · Cited by 26 · see citing works
Yang, H., Wang, S., Yang, L., Song, H., Zhang, G., He, Y., & Liu, H. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2023.109042 · Cited by 25 · see citing works
Wu, D., Li, J., Wang, J., Lei, J., Gan, R., Qin, P., Hu, Y., Wu, X., & Zou, L. (2024) · Food Research International · doi:10.1016/j.foodres.2024.114108 · Cited by 23 · see citing works
Casalvara, R. F. A., Ferreira, B. M. R., Gonçalves, J. E., Yamaguchi, N. U., Bracht, A., Bracht, L., Comar, J. F., de Sá‐Nakanishi, A. B., de Souza, C. G. M., Castoldi, R., et al. (2024) · Nutrients · doi:10.3390/nu16060840 · Cited by 23 · see citing works
Du, H., Lin, Y., Stanton, C., Daniloski, D., Zannini, E., Ross, R. P., & Miao, S. (2023) · Food Structure · doi:10.1016/j.foostr.2023.100342 · Cited by 22 · see citing works
Tan, M., Zhong, X., Xue, H., Cao, Y., Tan, G., & Li, K. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135192 · Cited by 22 · see citing works
Self-citationZang, Y., Ge, Y., Cao, Y., & Tang, H. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1308866 · Cited by 21 · see citing works
Wang, N., Qin, J., Chen, Z., Wu, J., & Xiang, W. (2024) · Molecules · doi:10.3390/molecules29194645 · Cited by 21 · see citing works
Jing, Y., Hu, J.-Y., Wang, Z., Tao, C., Zhang, S., Hu, B., & Li, Z. (2024) · Food & medicine homology. · doi:10.26599/fmh.2025.9420067 · Cited by 20 · see citing works
Li, H., Li, C., Yang, X., Cao, H., Wang, X., & He, J. (2025) · Journal of Cereal Science · doi:10.1016/j.jcs.2025.104108 · Cited by 20 · see citing works
Yue, X.-J., Xu, P., Zhu, Y., Hou, S.-B., Luo, X.-C., & Zhao, B. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.129076 · Cited by 20 · see citing works
Self-citationRen, T., Xiao, M., Zhou, Q., Li, H., Zhou, L., Wu, M., Gao, Z., Cao, Y., Wang, J., & Zhao, W. H. (2025) · Industrial Crops and Products · doi:10.1016/j.indcrop.2025.121111 · Cited by 17 · see citing works
Yu, D., Wang, W., Hou, S., Chang, M., Cheng, Y., Meng, J., Feng, C., Xu, L., Geng, X., Wang, S., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130777 · Cited by 17 · see citing works
Zhuansun, W., Xu, J., Liu, H., Zhao, Y., Chen, L., Shan, S., Song, S., Zhang, H., Dong, T., Zeng, H., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1032289 · Cited by 17 · see citing works
Yap, P., & Gan, C. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.136927 · Cited by 16 · see citing works
Gao, H., Shi, D., Yin, C., Fan, X., Cheng, X., Qiao, X., Liu, C., Hu, G., Yao, F., Qiu, J., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.137460 · Cited by 16 · see citing works
Wang, L., Zhang, Z., Zhao, W., Lin, C., Zhou, X., Pang, H., Qin, G., Li, H., & Ma, B. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.129034 · Cited by 15 · see citing works
Brito, I. D. L., Chantelle, L., Magnani, M., & Cordeiro, Â. M. T. D. M. (2022) · Journal of Food Processing and Preservation · doi:10.1111/jfpp.16601 · Cited by 15 · see citing works
Chen, X.-M., Dai, P.-F., Zhu, Y.-M., Jin, W.-W., Xie, Y., Yang, Z., Wang, Z.-Y., Jin, X., Lei, M.-J., Shi, L., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.124716 · Cited by 16 · see citing works
Chen, D., Kang, Z., Chen, H., & Fu, P. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130076 · Cited by 14 · see citing works
Cai, W., Wong, K., & Huang, Q. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124818 · Cited by 14 · see citing works
Dostalíková, L., Čepková, P. H., Janovská, D., Svoboda, P., Jágr, M., Dvořāček, V., & Viehmannová, I. (2023) · Foods · doi:10.3390/foods12071440 · Cited by 13 · see citing works
Song, S., Abubaker, M. A., Akhtar, M., Elimam, A. M., Zhu, X., & Zhang, J. (2024) · Foods · doi:10.3390/foods13060912 · Cited by 12 · see citing works
Kumar, R., Bhardwaj, S., Sikarwar, M., Kumar, A., Singh, B. R., Gupta, M., & Shukla, R. (2024) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2024.107133 · Cited by 12 · see citing works
Cao, Z., Wang, H., Feng, T., Yao, L., Sun, M. H., Song, S., Liu, Q., & Yu, C. (2025) · LWT · doi:10.1016/j.lwt.2025.117396 · Cited by 12 · see citing works
Zhang, Q., Huang, R., Wang, L., Ge, Y., Fang, H., & Chen, G. (2025) · Food Chemistry X · doi:10.1016/j.fochx.2025.102348 · Cited by 12 · see citing works
Zhao, C., Wang, W., Li, F. N., Sheng, J., He, R., You, L., & Tian, Y. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.147461 · Cited by 11 · see citing works
Yu, Y.-H., Liu, F., Li, L., Jin, M., Yu, X., Liu, X., Li, Y., Li, L., & Yan, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134130 · Cited by 9 · see citing works
Kim, K., Jeong, J., Park, S., Park, S.-I., & Jung, S. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.140007 · Cited by 8 · see citing works
Prompting immunostimulatory activity of curdlan with grafting methoxypolyethylene glycol
Luo, L., Zhou, Q., Hu, Y., Ding, Q., Zhou, Z., Wang, C., Wang, X., Li, H., & Tang, S. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.09.240 · Cited by 8 · see citing works
Xu, S., Shi, K., Jin, Y., Guo, Q. Q., Liu, H., Qin, Z., & Wang, X. (2024) · Journal of Food Science · doi:10.1111/1750-3841.17405 · Cited by 8 · see citing works
Xu, Z., Chen, C., Peng, C., Wang, H., He, Y., Zhang, X., He, X., Zeng, D., Li, L., & Hong, G. (2025) · LWT · doi:10.1016/j.lwt.2025.118210 · Cited by 7 · see citing works
Effects of Black Quinoa Polysaccharides on Obesity and Intestinal Flora Dysbiosis in T2DM Mice
Zang, Y., Wu, K., Liu, J., Yang, C., & Wang, C. (2024) · Journal of Food Biochemistry · doi:10.1155/2024/5473584 · Cited by 7 · see citing works
Cai, H., Yong, F., Li, R., Chen, J., Liu, X., Song, B., Wang, Z., Zhao, Q., & Zhong, S. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16101323 · Cited by 6 · see citing works
Self-citationFu, L., Ru, Y., Hong, Q., Weng, H., Zhang, Y., Chen, J., Xiao, A., & Xiao, Q. (2025) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2025.111495 · Cited by 6 · see citing works
Liu, R., Liu, R., Yan, X., Li, N., Li, M., Zhi, Z., Guo, B., & Zhang, M. (2023) · Fermentation · doi:10.3390/fermentation9030309 · Cited by 6 · see citing works
Zhang, Q., Huang, R., Chen, G., Guo, F., & Hu, Y. (2025) · Foods · doi:10.3390/foods14020238 · Cited by 5 · see citing works
Pecka‐Kiełb, E., Króliczewska, B., Król, B., Słupczyńska, M., Sowiński, J., ZACHWIEJA, A., Kaszuba, J., & Zigo, F. (2025) · Journal of Applied Animal Research · doi:10.1080/09712119.2025.2467119 · Cited by 5 · see citing works
Li, H., Li, C., Sun, Y., He, J., & Pan, D. (2025) · Plant Foods for Human Nutrition · doi:10.1007/s11130-024-01284-6 · Cited by 4 · see citing works
Wang, Y., Meng, K., Ji, Y., Hu, Q., & Zhao, L. (2025) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2025.111985 · Cited by 4 · see citing works
Quinoa and Colonic Health: A Review of Bioactive Components and Mechanistic Insights
Pan, Y., Zheng, J., Wang, Z., Lin, S.-H., Jia, H., Pei, H.-R., & Ju, R.-H. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47100815 · Cited by 5 · see citing works
Shen, F., Wu, H., Liu, Y., Wang, T., & Wu, Z. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.14299 · Cited by 4 · see citing works
Liu, L., Wang, H., Li, X., Zhang, L., Zhang, X., & Xu, X. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.139091 · Cited by 3 · see citing works
Sun, J., Wang, S., Duan, J., & Xiao, P. (2025) · Food Reviews International · doi:10.1080/87559129.2025.2553683 · Cited by 3 · see citing works
Madhumathi, R., Prashanth, K. V. H., & Inamdar, A. A. (2025) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-025-03246-1 · Cited by 2 · see citing works
Li, J., Zhang, L., Wu, D., Cao, Y., Cao, Y.-N., Feng, M.-L., Tan, M.-L., Yi-Chen, H. U., Zou, L., & Huang, J.-W. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107336 · Cited by 2 · see citing works
Self-citationKaur, S., Gadpayale, D. P., Kumari, A., Kaur, G., Kumar, A., Seem, K., Bhardwaj, R., & Riar, A. S. (2025) · Applied Food Research · doi:10.1016/j.afres.2025.101127 · Cited by 2 · see citing works
Liu, Y., Pan, Q., Bao, X., Zhang, Y., Liu, X., Liu, Y., Liu, Y., Zhang, Y., Xie, Q., Liang, Z., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.71250 · Cited by 1 · see citing works
Xiao, L., Gao, J., Jiang, S.-L., Jin, C.-R., Zhang, X., Kuang, H., Liang, J., & Xia, Y. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.154068 · Cited by 1 · see citing works
Carli, M., Guglielminetti, L., & Reyes, T. H. (2025) · Seeds · doi:10.3390/seeds4030046 · Cited by 1 · see citing works
Lin, J., Jiang, T., Zhang, X., Lu, X., Gong, Y., & Liao, W. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.71010 · Cited by 1 · see citing works
The Therapeutic Potential of TCM Polysaccharides in Neurological Disorders
Wang, H. W., Xu, X., Deng, W., He, Y., & yuan, L. (2026) · Chemistry & Biodiversity · doi:10.1002/cbdv.71105 · Cited by 1 · see citing works
Saravani, A. F., Rabiei, B., & Laki, E. S. (2026) · Scientific Reports · doi:10.1038/s41598-026-41896-3 · Cited by 1 · see citing works
Aroonkesorn, A., Sukprasirt, P., Dumidae, A., Buaking, M., Wititsuwannakul, R., & Pitakpornpreecha, T. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.153208 · Cited by 1 · see citing works
Zhang, S., Zhang, Y., Liu, H., Xing, H., Tian, Y., Lv, J., Zhang, X., & Zhang, X. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.142679 · Cited by 1 · see citing works
Food and nonfood applications of quinoa fractionated products
Zhu, F. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99909-0.00003-9
Fouda, W. A. (2024) · Journal of Animal and Poultry Production · doi:10.21608/jappmu.2024.260781.1103
Teng, C., Guo, S., Li, Y., & Ren, G. (2024) · Foods · doi:10.3390/foods13152311
Li, N., Feng, X., Xu, Y., Li, S.-Y., Zhang, Y., Fan, L., Wu, X., & Dong, L. (2026) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2026.04.005
Wang, Q., Zhao, W., Wu, Y., Liao, Y., Zhou, W., Xie, D., & Jin, Y. (2026) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2026.152203
Zhou, Y.-L., Li, X., You, X., Wang, X.-Y., Jing-shun, W., Zhang, K.-P., Shen, Y.-J., & Zhang, K.-J. (2026) · Journal of Food Processing and Preservation · doi:10.1155/jfpp/6154858
Bieogo, E. W. W., Istrati, D. I., Vizireanu, C., Dao, A., Constantin, O. E., Pricop, E. M., Garnai, M., Nikièma, P. A., & Sawadogo-Lingani, H. (2026) · Life · doi:10.3390/life16071064
Liu, Y., Wang, T., Zhang, Y., Jia, Z., An, C., Yang, Y., Su, L., & Li, Y. (2026) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.70875
Khimmaktong, W., Lorthong, N., Dumidae, A., Sukprasirt, P., Wititsuwannakul, R., Aroonkesorn, A., & Pitakpornpreecha, T. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.109819
- Authors
- Tan, M., Zhao, Q., & Zhao, B.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Zhao, Qingsheng
- Zhao, Bing
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2021-12
- Volume
- 193
- Issue
- Pt B
- Pages
- 1635-1644
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W3214112168
- Cited by
- 85
- References
- 54
- Citations by year
- 2026: 11 · 2025: 23 · 2024: 24 · 2023: 13 · 2022: 14
- FWCI
- 7.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- International Journal of Biological Macromolecules (publishedVersion)
- PubMed (publishedVersion)
- Institute of Process Engineering, CAS Institutional Repository (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Seed and Plant Biochemistry
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- quinoa, polysaccharide fractionation, membrane separation, ultrafiltration, microfiltration, heteropolysaccharide, triple helix, monosaccharide composition, antioxidant activity, antidiabetic activity, immunomodulatory activity, RAW 264.7 macrophages, functional foods
- MeSH terms
- RAW 264.7 Cells, Animals, Antioxidants, Cell Line, Glucose, Hypoglycemic Agents, Monosaccharides, Polysaccharides, Seeds, Chenopodium quinoa, Mice
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