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Citrulline Malate Fails to Improve German Volume Training Performance in Healthy Young Men and Women

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Combined L-Citrulline Supplementation and Slow Velocity Low-Intensity Resistance Training Improves Leg Endothelial Function, Lean Mass, and Strength in Hypertensive Postmenopausal Women

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Combined Citrulline and Glutathione Supplementation Improves Endothelial Function and Blood Pressure Reactivity in Postmenopausal Women

Figueroa, A., Maharaj, A., Kang, Y., Dillon, K. N., Martinez, M. A., Morita, M., Nogimura, D., & Fischer, S. M. (2023) · Nutrients · doi:10.3390/nu15071557 · Cited by 18 · see citing works

Citrulline production and protein homeostasis

Ginguay, A., & Bandt, J. P. D. (2019) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000585 · Cited by 18 · see citing works

Effect of chronic nitrate and citrulline supplementation on vascular function and exercise performance in older individuals

Roux‐Mallouf, T. L., Pelen, F., Vallejo, A., Halimaoui, I., Doutreleau, S., & Vergès, S. (2019) · Aging · doi:10.18632/aging.101984 · Cited by 18 · see citing works

What are the metabolic precursors which increase the risk of pre-eclampsia and how could these be investigated further

Myers, J. (2017) · Placenta · doi:10.1016/j.placenta.2017.08.011 · Cited by 16 · see citing works

Eight Days of L-Citrulline or L-Arginine Supplementation Did Not Improve 200-m and 100-m Swimming Time Trials

Esen, Ö., Mustafa, E. S. E. R., Abdioğlu, M., Benešová, D., Gabrys, T. T., & Karayiğit, R. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084462 · Cited by 15 · see citing works

Recent Advances in Amino Acid Production

Ikeda, M., & Takeno, S. (2020) · Microbiology monographs · doi:10.1007/978-3-030-39267-3_7 · Cited by 15 · see citing works

Effects of l -citrulline supplementation and watermelon consumption on longer-term and postprandial vascular function and cardiometabolic risk markers: a meta-analysis of randomised controlled trials in adults

Smeets, E. T. H. C., Mensink, R. P., & Joris, P. J. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521004803 · Cited by 14 · see citing works

A Critical Review on Vasoactive Nutrients for the Management of Endothelial Dysfunction and Arterial Stiffness in Individuals under Cardiovascular Risk

da Silva, D. V. T., Baião, D. D. S., de Almeida, C. C., & Paschoalin, V. M. F. (2023) · Nutrients · doi:10.3390/nu15112618 · Cited by 15 · see citing works

L-Citrulline supplementation attenuates aortic pulse pressure and wave reflection responses to cold stress in older adults

Jaime, S. J., Nagel, J., Maharaj, A., Fischer, S. M., Schwab, E., Martinson, C., Radtke, K., Mikat, R. P., & Figueroa, A. (2022) · Experimental Gerontology · doi:10.1016/j.exger.2021.111685 · Cited by 13 · see citing works

Effects of L-Citrulline Supplementation and Aerobic Training on Vascular Function in Individuals with Obesity across the Lifespan

Flores-Ramírez, A. G., Tovar-Villegas, V. I., Maharaj, A., Garay‐Sevilla, M. E., & Figueroa, A. (2021) · Nutrients · doi:10.3390/nu13092991 · Cited by 12 · see citing works

Wild Watermelon-Extracted Juice Ingestion Reduces Peripheral Arterial Stiffness with an Increase in Nitric Oxide Production: A Randomized Crossover Pilot Study

Fujie, S. J., Iemitsu, K., Inoue, K., Ogawa, T., Nakashima, A., Suzuki, K., & Iemitsu, M. (2022) · Nutrients · doi:10.3390/nu14245199 · Cited by 12 · see citing works

Effect of L-citrulline intake on intermittent short-time high-intensity exercise performance in male collegiate track athletes

Terasawa, N., & Nakada, K. (2019) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.8.147 · Cited by 12 · see citing works

Effect of oral L-citrulline on brachial and aortic blood pressure defined by resting status: evidence from randomized controlled trials

Yang, H., Li, X., Zhang, W.-G., Figueroa, A., Chen, L., & Qin, L. (2019) · Nutrition & Metabolism · doi:10.1186/s12986-019-0415-y · Cited by 12 · see citing works

Combined l-citrulline and glutathione administration prevents neuronal cell death following transient brain ischemia

Matsuo, K., Yabuki, Y., & Fukunaga, K. (2017) · Brain Research · doi:10.1016/j.brainres.2017.03.014 · Cited by 11 · see citing works

Effects of L-citrulline diet on stress-induced cold hypersensitivity in mice

Kobayashi, Y., Narita, K., Chiba, K., Morita, M., Morishita, K., & Takemoto, H. (2014) · Pharmacognosy Research · doi:10.4103/0974-8490.138269 · Cited by 9 · see citing works

Asymmetric dimethylarginine and arginine levels in patients with rheumatoid arthritis

Vatansev, H., Öztürk, B., Yi̇lmaz, S., Sivrikaya, A., Dağlı, M., Kıyıcı, A., & Ünlü, A. (2013) · Turkish Journal of Biochemistry · doi:10.5505/tjb.2013.51523 · Cited by 8 · see citing works

Association between brachial-ankle pulse wave velocity and the ratio of l-arginine to asymmetric dimethylarginine in patients undergoing coronary angiography

Masaki, N., Hakuno, D., Toya, T., Shiraishi, Y., Kujiraoka, T., Namba, T., Yada, H., Kimura, K., Miyazaki, K., & Adachi, T. K. (2014) · Journal of Cardiology · doi:10.1016/j.jjcc.2014.06.005 · Cited by 8 · see citing works

Oral administration of l-citrulline alters the vascular delivery of substances to rat skeletal muscles

Miyatake, S., Hino, K., Ebisu, G., & Fujita, S. (2021) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2021.101149 · Cited by 8 · see citing works

Inter-Individual Responses to Citrulline Malate Oral Supplementation on Post-Exercise Hypotension in Hypertensives: A 24-Hour Analysis

Casonatto, J., Enokida, D. M., & Grandolfi, K. (2019) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20190115 · Cited by 8 · see citing works

Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials

Luo, P., Chen, J., Liu, K., & Zhang, J. (2025) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2025.07.1130 · Cited by 7 · see citing works

CHronic hypERtension and L-citRulline studY (CHERRY): an Early-Phase Randomised Controlled Trial in Pregnancy

Ormesher, L., Worton, S. A., Best, A., Dodd, S. R., Dempsey, A., Cottrell, E. C., Glossop, H., Chmiel, C., Wu, T. H.-Y., Hardwick, B., et al. (2023) · Reproductive Sciences · doi:10.1007/s43032-023-01335-4 · Cited by 7 · see citing works

Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial

Rodríguez-Carrillo, A., Espinoza-Vargas, M., Vargas‐Ortiz, K., Ibarra‐Reynoso, L. D. R., Olvera-Juárez, M., Gómez-Ojeda, A., Garay‐Sevilla, M. E., & Figueroa, A. (2025) · Nutrients · doi:10.3390/nu17030402 · Cited by 7 · see citing works

Effects of L-citrulline supplementation and watermelon intake on arterial stiffness and endothelial function in middle-aged and older adults: a systematic review and meta-analysis of randomized controlled trials

Luo, P., Li, Z., Liu, K., & Gao, W. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1632952 · Cited by 6 · see citing works

Short-Term L-Citrulline Supplementation Does Not Affect Blood Pressure, Pulse Wave Reflection, or Arterial Stiffness at Rest and during Isometric Exercise in Older Males

Tryfonos, A., Christodoulou, F., Pamboris, G. M., Christodoulides, S., & Theodorou, A. A. (2023) · Sports · doi:10.3390/sports11090177 · Cited by 6 · see citing works

Untargeted metabolomic analysis uncovers metabolic variability of four Bifidobacterial strains for probiotic development

Liu, K., Yao, G., Zhan, Y., Huang, T., Kwok, L., & Zhang, H. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1522036 · Cited by 6 · see citing works

Collagen type IV as the link between arterial stiffness and dementia.

Rabkin, S. W. (2023) · PubMed Central · Cited by 6 · see citing works

“Unveiling the impacts of climatic cold events on the cardiovascular health in animal models”

Priya, A., Mol, N., Singh, A. K., Aditya, A. K., & Ray, A. K. (2025) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2025.179028 · Cited by 5 · see citing works

Effect of microencapsulated watermelon (Citrullus lanatus) intake on plasma amino acids and glycemic response in healthy adults

Volino‐Souza, M., de Oliveira, G. V., Vargas, R., Tavares, A. C., Conte‐Júnior, C. A., & Álvares, T. S. (2022) · Food Bioscience · doi:10.1016/j.fbio.2022.101553 · Cited by 5 · see citing works

Citrulline malate supplementation might potentiate post-exercise hypotension in hypertensives: A 24-hour analysis

Casonatto, J., Cavalari, J. V., Goessler, K. F., Christófaro, D. G. D., Polito, M. D., Enokida, D. M., & Grandolfi, K. (2019) · Science & Sports · doi:10.1016/j.scispo.2019.03.001 · Cited by 5 · see citing works

Mechanisms of L-citrulline on phosphodiesterase 5 in erectile dysfunction intervention

Sulyman, A. O., Aliyu, O. M., Ajani, E. O., Abdulkareem, Y. F., Afe, I. A., Abdulyakeen, F. O., Lukman, H. Y., Sabiu, S., Singh, K., & Naidoo, K. (2025) · Scientific African · doi:10.1016/j.sciaf.2025.e02572 · Cited by 4 · see citing works

Short-Term L-Citrulline Supplementation Does Not Affect Inspiratory Muscle Oxygenation and Respiratory Performance in Older Adults

Theodorou, A. A., Chatzinikolaou, P. N., Margaritelis, N. V., Christodoulou, F., Tsatalas, T., & Paschalis, V. (2023) · Nutrients · doi:10.3390/nu15081951 · Cited by 3 · see citing works

Empagliflozin increases plasma levels of citrulline, histidine, and α-aminobutyric acid in patients with type 2 diabetes: effects of a sodium-glucose co-transporter 2 inhibitor on the plasma amino acid profile

Jojima, T., Sakurai, S., Kishi, H., Kato, K., Iijima, T., Tomaru, T., Usui, I., & Aso, Y. (2024) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2024.2362265 · Cited by 4 · see citing works

SNP associations in the L-citrulline metabolic pathway and vascular aging in the Japanese population

Nogimura, D., Moriyasu, K., Ishida, S., Kohda, M., Yazawa, T., & Morita, M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0323778 · Cited by 3 · see citing works

NADPH oxidase, uncoupled endothelial nitric oxide synthase, and NF-KappaB are key mediators of the pathogenic impact of obstructive sleep apnea – Therapeutic implications

McCarty, M. F., DiNicolantonio, J. J., & O’Keefe, J. H. (2016) · Journal of Integrative Cardiology · doi:10.15761/jic.1000177 · Cited by 3 · see citing works

Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials

Karimi, E., Abaj, F., Gholizadeh, M., Asbaghi, O., Amini, M. R., Ghaedi, E., & Hadi, A. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110801 · Cited by 3 · see citing works

Improvements of Doxorubicin-Induced Antitumor Activity and Adverse Reaction by Combined Citrulline

Miyashita, M., & Sadzuka, Y. (2014) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00811 · Cited by 3 · see citing works

Effects of L-Citrulline Supplementation on Endothelial Function, Arterial Stiffness, and Blood Glucose Level in the Fasted and Acute Hyperglycemic States in Middle-Aged and Older Adults with Type 2 Diabetes

Kang, Y., Dillon, K. N., Levitt, D. E., & Figueroa, A. (2025) · Nutrients · doi:10.3390/nu17233739 · Cited by 2 · see citing works

Targeting muscle–vasculature crosstalk in aging through the integrative roles of L-citrulline, leucine, and exercise: focus on muscle metabolism, vascular function, and sarcopenia prevention

Lin, X., Zhang, Y., Pu, J., & Peng, Y. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1739173 · Cited by 2 · see citing works

Acute citrulline oral supplementation induces greater post-exercise hypotension response in hypertensive than normotensive individuals

Grandolfi, K., Cavalari, J. V., GÓES, R. C., Polito, M. D., & Casonatto, J. (2018) · Revista de Nutrição · doi:10.1590/1678-98652018000600001 · Cited by 2 · see citing works

Therapeutic potential of gasotransmitters for cold stress-related cardiovascular disease

Sun, H., Nie, X., Yu, K.-Y., & Bian, J. (2022) · Frigid Zone Medicine · doi:10.2478/fzm-2022-0002 · Cited by 2 · see citing works

The Acute Effect of Citrulline Malate Loading in Resistance Trained Males on: Anaerobic Muscular Endurance, Force Recovery and Muscle Soreness

Chappell, A., Parry, A., & Simper, T. N. (2024) · Journal of Science in Sport and Exercise · doi:10.1007/s42978-024-00288-7 · Cited by 2 · see citing works

Potential Therapeutic Effects of Empagliflozin Through Elevated Plasma Citrulline Levels in Heart Failure With Preserved Ejection Fraction

Tsuruta, Y., Kitada, S., Kawada, Y., Shintani, Y., Mizoguchi, T., Yokoi, M., Yamabe, S., Mori, K., Kikuchi, S., Ito, T., et al. (2025) · Circulation Journal · doi:10.1253/circj.cj-24-0953 · Cited by 2 · see citing works

A 4-week oral gavage toxicity study of L-citrulline in rats

Morita, M., Yamaguchi, T., Morishita, K., & Kamimura, A. (2017) · Fundamental Toxicological Sciences · doi:10.2131/fts.4.219 · Cited by 2 · see citing works

Building Muscle Mass: Physiology, Nutrition, and Supplementation

Levers, K. S., & Vargo, K. (2015) · Springer eBooks · doi:10.1007/978-3-319-18230-8_7 · Cited by 1 · see citing works

The effects of L-Citrulline on thermoregulation and vascular function

(2015) · Queen Margaret University Publications Repository (Queen Margaret University)

Short-Term L-Citrulline Supplementation Does Not Affect Blood Pressure, Pulse Wave Reflection, or Arterial Stiffness at Rest and during Isometric Exercise in Older Males

Tryfonos, A., Christodoulou, F., Pamboris, G. M., Christodoulides, S., & Theodorou, A. A. (2023) · Sports · doi:10.3390/sports11090177 · Cited by 6 · see citing works

The effect of L-citrulline ingestion on cardiovascular function

Thadathil, J. (2015) · Queen Margaret University eTheses Repository

Effect of Systemic Nitric Oxide Synthase Inhibition on Arterial Stiffness in Humans

Sugawara, J., Komine, H., Hayashi, K., Yoshizawa, M., Yokoi, T., Otsuki, T., Shimojo, N., Miyauchi, T., Maeda, S., & Tanaka, H. (2006) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-200605001-01703 · Cited by 3 · see citing works

The influence of L-arginine on vascular endothelial function at rest and during sympathetic activation

Wells, A. (2017) · California State University ScholarWorks (system-wide DSpace)