Trends in mortality after first hospitalization with Atrial Fibrillation diagnosis in Sweden 1987 to 2006
Abstract
Background To examine trends in 3-year mortality after a first hospitalization with diagnosed atrial fibrillation in a large cohort with and without important comorbidities.Methods The Swedish Hospital Discharge and Cause of Death Registries were linked to investigate trends in mortality for all patients 35 to 84 years hospitalized for the first time with a discharge diagnosis (principal or contributory) of atrial fibrillation in Sweden during 1987 to 2006.We performed an analysis of temporal trends in mortality stratified for presence or absence of co-morbidities affecting survival.Results Exactly 376,000 patients (56% male, mean age 72 years) with a first diagnosis of atrial fibrillation during 1987–2006 were identified and followed for 3 years. Patients with one or more of the prespecified comorbidities had the highest mortality and the largest absolute decline in mortality, but patients without these comorbidities had a slightly larger relative decline (absolute risk reduction in 3-year mortality (AAR) from 42.5 to 34.7%, Hazard Ratio (HR) 0.76; 95% confidence interval (95% CI) 0.74 to 0.77 versus ARR 16.2% to 11.7%, HR 0.71; 0.68 to 0.74. In patients aged below 65 years,with no comorbidities, there was minimal change inmortality, and they still had a 2 times increased mortality compared to the general population (SMR 1.95; 1.84-2.06).Conclusions Survival after a first hospitalization with a diagnosis of atrial fibrillation improved regardless comorbidities. Patients aged < 65 years old without diagnosed comorbidities still had a poor prognosis compared to the general population.
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PR interval is shorter in women compared with men.
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- Authors
- Olsson, L. G., Swedberg, K., Lappas, G., Stewart, S., & Rosengren, A.
- Affiliations
- Mora lasarett (SE)
- University of Gothenburg (SE)
- Baker Heart and Diabetes Institute (AU)
- Corresponding author
- Olsson, L.G.
- Venue
- International Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2013-12
- Volume
- 170
- Issue
- 1
- Pages
- 75-80
- ISSN
- 0167-5273 (ISSN-L)
- OpenAlex
- W2048989218
- Cited by
- 10
- References
- 34
- Citations by year
- 2022: 1 · 2020: 1 · 2019: 1 · 2016: 3 · 2015: 3 · 2014: 1
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Research Bank (Australian Catholic University) (submittedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- atrial fibrillation, mortality trends, first hospitalization, comorbidities, survival after hospital discharge, temporal trends, age differences in mortality, hospital discharge diagnoses, causes of death
- MeSH terms
- Adult, Aged, Aged, 80 and over, Atrial Fibrillation, Female, Hospitalization, Humans, Male, Middle Aged, Patient Discharge, Sweden, Cohort Studies
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